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| Number | Title | Issue Date |
| 7270857 | Liquid crystal composition and liquid crystal element The present invention relates to a liquid crystal composition comprising a compound represented by the following formula (1) and a liquid crystal and a liquid crystal element containing the liquid crystal composition: ... | 09/18/2007 |
| 7041821 | Synthetic molecules for labeling histidine-rich proteins The invention provides Zn-chelating compounds that are molecularly engineered to bind to a specific target sequence in a protein of interest. The Zn2+ ion is far less toxic and promiscuous than nickel and therefore provides an attractive alternative to Ni... | 05/09/2006 |
| 6992092 | Anti-diabetic agents The present invention provides compounds of formula (I) the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds, stereoisomers, and prodrugs; wherein R1, R2 | 01/31/2006 |
| 6933384 | Synthetic molecules for labeling histidine-rich proteins The invention provides Zn-chelating compounds that are molecularly engineered to bind to a specific target sequence in a protein of interest. The Zn2+ ion is far less toxic and promiscuous than nickel and therefore provides an attractive alternative to Ni... | 08/23/2005 |
| 6703401 | Compounds, their preparation and use The present invention relates to compounds of the general formula (I) ##STR1## The compounds are useful in the treatment and/or prevention of conditions mediated by clear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).... | 03/09/2004 |
| 6365586 | Compounds, their preparation and use The present invention relates to compounds of the general formula (I) ##STR1## The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).... | 04/02/2002 |
| 6270695 | Compounds, compositions, and methods for generating chemiluminescence with phosphatase enzymes Novel heterocyclic compounds which generate chemiluminescence on reaction with a phosphatase enzyme are provided as well as a process for their preparation and intermediates useful therein. The compounds comprise a nitrogen, oxygen or sulfur-containing he... | 08/07/2001 |
| 6159966 | Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them A compound of formula (I) ##STR1## its tautomeric forms, its stereoisomers, its polymorphs, its pharmaceutically acceptable salts or its pharmaceutically acceptable solvates, wherein R3, R4, R5, and R6 are ... | 12/12/2000 |
| 6117869 | Compounds for and methods of inhibiting matrix metalloproteinases The present invention relates to compounds of Formula I that inhibit matrix metalloproteinases and to a method of inhibiting matrix metalloproteinases using the compounds ##STR1## More particularly, the present invention relates to a method of treati... | 09/12/2000 |
| 5792389 | Water soluble laser dyes Novel water soluble dyes of the formula I are provided ##STR1## wherein R1 and R4 are alkyl of 1 to 4 carbon atoms or hydrogen; or R1 -R2 or R2 -R4 form part of aliphatic heterocyclic ... | 08/11/1998 |
| 5714606 | Pyrrolidine-containing monomers and oligomers The invention relates to pyrrolidine monomeric units and to oligomers which are joined via phosphate linkages, including phosphorothioate, phosphodiester and phosphoramidate linkages.... | 02/03/1998 |
| 5656759 | Hydrophobic cationic dye compounds When the counter ion of hydrophilic cationic dyes is substituted with an organic anion including a sulfosuffinate anion such as diethylhexylsulfonate anion, an alkylbenzenesulfonate anion such as a dodecylbenzenesulfonate, an alkylsulfate anion such as a ... | 08/12/1997 |
| 5519134 | Pyrrolidine-containing monomers and oligomers Novel pyrrolidine monomers bearing various functional groups are used to prepare oligomeric structures. The pyrrolidine monomers can be joined via standard phosphate linkages including phosphodiester and phosphorothioate linkages. Useful functional groups... | 05/21/1996 |
| 5391482 | Method and diagnostic agent for enzyme substrate stabilization using 1-arylsemicarbazides The present invention is concerned with the use of 1-arylsemicarbazides of the general formula: Ar--NH--NH--CON2 wherein Ar is an aryl radical optionally substituted by alkyl, alkoxy or halogen, for the stabilization of an enzyme substrate from whic... | 02/21/1995 |
| 5319074 | Bifunctional reactive dyestuffs containing vinylsulphone or alkylsulphone groups and a 2,4 difluoro pyrimidine group A metal-free dyestuff of the formula ##STR1## and metal complex thereof wherein: Fb=the radical of a dyestuff selected from the group consisting of mono- or polyazo, anthraquinone, phthalocyanine, formazan, dioxazine and triphenylmethane radicals, B ... | 06/07/1994 |
| 5298607 | Reactive dyes containing fluorotriazine and vinylsulfonyl radicals The invention provides reactive dyes of the formula ##STR1## wherein D is a mono- or polyazo, metal complex azo, anthraquinone, phthalocyanine, formazane, dioxazine or stilbene dye which contains sulfo groups, R1 is hydrogen or C1 | 03/29/1994 |
| 5246989 | Photochromic compound, composition and use thereof A photochromic compound of the present invention is a spiroxazine compound represented by the following formula: ##STR1## wherein R1 to R3 represent a monovalent organic group such as alkyl group, Y represents a fused heterocycl... | 09/21/1993 |
| 5238936 | Trisubstituted triazines The compounds are trisubstituted triazines and pyrimidines useful for the suppressing the resistance of tumour cells to anti-cancer agents and for suppressing the resistance of parasites to anti-parasitic agents. A compound disclosed is 2,4-diallylamino-6... | 08/24/1993 |
| 4954630 | Resorufin derivatives The present invention provides resorufin derivatives of the general formulae: ##STR1## wherein R1, R2, R3, R4 and R5, which can be the same or different, are hydrogen, halogen, carboxyl, carboxam... | 09/04/1990 |
| 4912258 | Fluorinated aniline derivatives and their use Fluorinated aniline derivatives of the general formula I are described ##STR1## in which R1 represents H or (CH2)n -X, n is a whole number from 1 to 3, X is H, OH, NH2, CH3 CONH, CH3 SO | 03/27/1990 |
| 4900822 | New hydrolase substrates Reagents for the determination of hydrolase comprises compounds of the formula ##STR1## wherein Z is an organic or inorganic acid residue or a sugar residue, A is an organic or inorganic acid residue, and B is an organic acid residue. Each of R | 02/13/1990 |
| 4861775 | Pharmacological use of phenoxazinones Streptomyces spec. DSM 3813 produces novel compounds with a basic phenoxazinone structure, which have an antifungal and antiviral action and can be used as lipoxygenase inhibitors.... | 08/29/1989 |
| 4859667 | Pharmaceutical compositions of phenothiazone derivatives and analogs Phenothiazone derivatives and analogs thereof, pharmaceutical compositions and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for t... | 08/22/1989 |
| 4847376 | Lipase substrates The present invention provides a lipase substrate of the general formula: ##STR1## wherein A is an alkylene or alkenylene radical containing up to 16 carbon atoms, R and R1, which can be the same or different, each signify an alkyl, alkeny... | 07/11/1989 |
| 4837235 | Indole and indazole keto sulphones as leukotriene antagonists This invention provides a series of novel keto sulfones of formula I ##STR1## in which the group .dbd.A-- is selected from .dbd.C(Ra)-- and .dbd.N-- and the other radicals have the meanings defined in the following specification. The compounds of for... | 06/06/1989 |
| 4803269 | 4-monosubstituted and 4,6-disubstituted N-(-phenylethyl)phenoxazines 4-Monosubstituted and 4,6-disubstituted phenoxazines, methods of preparing them and pharmaceutical compositions containing them. These compounds are useful as anti-inflammatories.... | 02/07/1989 |
| 4741765 | Herbicidal sulfonamides Benzenesulfonamide compounds such as N-[(4,6-dimethoxy-1,3,5-triazin-2-yl)aminocarbonyl]-1,4-dihydro-3-methyl-4 -oxo-1-phenyl-indeno[1,2-C]pyrazole-5-sulfonamide and N-[(4-methoxy-6-methyl-pyrimidin-2-yl)aminocarbonyl]-1,4-dihydro-3-methyl- 4-oxo-1-phe... | 05/03/1988 |
| 4710570 | Azine redox dyes and leuco azine dyes Azine redox dyes and their corresponding dyes of the formula: ##STR1## in which: X is O, S, NR2, Z completes a fused aromatic of heterocyclic ring system, n is 0 or 1 to allow one R1 ring substituent, Q represents CR4 R5 | 12/01/1987 |
| 4707473 | 4-monosubstituted and 4,6-disubstituted phenoxazines 4-Monosubstitued and 4,6-disubstituted phenoxazines, methods of preparing them and pharmaceutical compositions containing them. These compounds are useful as anti-inflammatories.... | 11/17/1987 |
| 4668671 | Tricyclic derivatives and pharmaceutical use This invention describes tricyclic derivatives which are useful as histamine H1 -antagonists. A particular compound of this invention is 3-[3-(pyrido[3,2-b][1,4]-benzothiazin-10-yl)propylamino]-4-(pyrid-4-ylmeth ylamino)-1,2,5-thiadiazole-1-oxid... | 05/26/1987 |
| 4667032 | Phenothiazone derivatives and analogs Phenothiazone derivatives and analogs thereof, pharmaceutical compositions and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for t... | 05/19/1987 |
| 4652646 | Thiazolo[3,2-a][1,2,3]triazolo[4,5-d]pyrimidine and [1,3,4]thiadiazolo[3,2-a][1,2,3]triazolo[4,5-d]pyrimidine derivatives Novel triazolopyrimidine compounds represented by the formula (I) and physiologically acceptable salts thereof are disclosed. These compounds have an excellent anti-allergic activity in oral administration and are useful for treatment and prophylaxis of a... | 03/24/1987 |
| 4366314 | Dimethine dyestuffs, their preparation and their use for dyeing synthetic and natural materials Styryl dyestuffs of the general formula ##STR1## wherein Het represents a pyridinium radical having the structure ##STR2## R and R1 independently of one another designate lower alkyl or alkenyl groups, which can be substituted by non-... | 12/28/1982 |
| 4305874 | Aniline azo dyes from 1,2,3,4-tetrahydroquinoline and 2,3-dihydro-1,4-benzoxazine couplers containing sulfate alkyl groups Disclosed are novel dyes which comprise aniline diazo moieties and certain aromatic amine couplers having sulfate groups. These dyes are substantially water soluble and are particularly useful for dyeing polyamide, wool and the like and exhibit, for examp... | 12/15/1981 |
| 4258182 | Quaternized amino-substituted styryl dyestuffs Styryl dyestuffs of the formula ##STR1## wherein Q.sym. represents a grouping containing a quaternary nitrogen atom and A represents a bridge member, at least one of the radicals R and R1 denotes a carbocyclic or heterocyclic 5-membered or... | 03/24/1981 |
| 4246404 | Basic indoline dyestuffs Basic dyestuffs free of sulphonic acid groups contain an indoline group the 2-position of which is connected through a vinylene group to the N-atom of a 2,3-dihydro-4H-1,4-benzoxazine group. The dyestuffs are useful for the dyeing of leather, paper and pl... | 01/20/1981 |
| 4131673 | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.... | 12/26/1978 |
| 4117127 | N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.... | 09/26/1978 |
| 4093712 | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.... | 06/06/1978 |
| 4066773 | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.... | 01/03/1978 |