"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 7662958 | Anti-infective agents The present invention provides HCV polymerase inhibiting compounds having the formula (I): where R1 is cyclobutyl-N(Ra)—, n is 1, 2, 3 or 4, and at least one R5 is RaSO2 | 02/16/2010 |
| 7425552 | Pyridazinone compounds The invention is directed to pyridazinone compounds of Formula I and pharmaceutical compositions containing compounds of Formula I wherein R1 and R2 are independently H, alkyl, cycloalkyl, aryl, or het... | 09/16/2008 |
| 7196194 | Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound A yellow dye-forming coupler represented by formula (I): wherein Q represents a group of nonmetallic atoms that form a 5- to 7-membered ring in combination with the —N═C—N(R1)—; R1 and... | 03/27/2007 |
| 7105511 | Fluorescent fused-ring triazoles that inhibit cell proliferation and uses thereof Fused-ring triazole compounds which inhibit proliferation of cells and exhibit a unique and intense fluorescence are provided. Also provided are methods for synthesizing these compounds and methods for using these compounds to inhibit cell proliferation and infectio... | 09/12/2006 |
| 6562811 | Pyridine derivatives Pyridine compounds of general formula: ##STR1## wherein --R1 represents ##STR2## in which R11 is hydrogen, C1-6 alkyl, halogen, hydroxy, C1-12 alkoxy, nitro, amino, C1-6 alkylsulfonylamino, C1-6 | 05/13/2003 |
| 6525000 | Method for producing anellated triazoles and new anellated triazoles and their use A process for preparing fused triazoles of formula I ##STR1## where: X--X is C--O, C--S, C--SO, C--SO2, or C--NR1 ; V is C.dbd.W2, R1 R2 C--C(.dbd.W2)-- or C(.dbd.V2)--C(.dbd.W2 | 02/25/2003 |
| 6432945 | Dipeptide derivatives This invention is directed to compounds of the formula ##STR1## and the pharmaceutically-acceptable salts thereof, where the substituents are as defined in the Specification, which are growth hormone secretogogues and which increase the level of endogenou... | 08/13/2002 |
| 6329367 | Fused 1,2,4-thiadiazine derivatives, their preparation and use The present invention relates to 4H-thieno[3,2-e]-1,2,4-thiadiazine derivatives of the general formula: ##STR1## wherein X, Y, R1, R2 and R3 are defined in the description, compositions thereof and methods for preparing th... | 12/11/2001 |
| 6225310 | Fused 1,2,4-thiadiazine derivatives, their preparation and use 1,2,4-Thiadiazine and 1,4-thiazine derivates represented by formula (I): ##STR1## wherein A, B, D, R1, R2, R3 and R4 are defined in the description, compositions thereof and methods for preparing the compounds a... | 05/01/2001 |
| 6197766 | Insecticidal dihydrooxadiazine compounds Insecticidal dihydrooxadiazine compounds having the formula: ##STR1## wherein X is O, N or S; R is a substituted or unsubstituted phenyl or C4 -C5 heterocyclic group; R2, R3, R4, and R5 are one ... | 03/06/2001 |
| 6011034 | Insecticidal dihydrooxadiazine compounds Insecticidal dihydrooxadiazine compounds having the formula: ##STR1## wherein X is O or S; R is a substituted or unsubstituted phenyl or heterocyclic group; R1 is halogen, haloalkyl or haloalkoxy; R2, R3 , and R4... | 01/04/2000 |
| 5889002 | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use 1,2,4-Thiadiazine and 1,4-thiazine derivatives represented by the formula ##STR1## wherein A, B, D, R1, R2, R3 and R4 are defined in the description, compositions thereof and methods for preparing the compounds ... | 03/30/1999 |
| 5811545 | Dyes for use in diverse applications The synthesis and the application of new dyes is described. In particular said new dyes can be incorporated in non-migratory state in hydrophilic colloid layers of photographic materials wherefrom they can be rapidly removed after being quickly decolorise... | 09/22/1998 |
| 5811546 | Dyes for use in diverse applications The synthesis and the application of new dyes is described. In particular said new dyes can be incorporated in non-migratory state in hydrophilic colloid layers of photographic materials wherefrom they can be rapidly removed after being quickly decolorize... | 09/22/1998 |
| 5792764 | Pyrido-1,2,4-thiadiazine and pyrido-1,4-thiazine derivatives, their preparation and use Pyrido-1,2,4-thiadiazine and pyrido-1,4-thiazine derivatives represented by the formula ##STR1## wherein A, B, D, R1, R2, R3 and R4 are defined in the description, compositions thereof and methods for prepa... | 08/11/1998 |
| 5739326 | Heterobicyclic herbicides Compounds of Formula I, and their N-oxides and agriculturally-suitable salts, are disclosed which are useful for controlling undesired vegetation ##STR1## wherein: X and Y are independently N or CH; Z is O, S(O)n, NR7, C(.dbd.O), C(.... | 04/14/1998 |
| 5599815 | Antipsychotic benzoisothiazolyl piperazine derivatives Compounds represented by the formula (I) and pharmacologically acceptable salts thereof: ##STR1## These compounds have little extrapyramidal effect and thus are effective as an anti-psychotic agent having few side effects.... | 02/04/1997 |
| 5580869 | 1N substituted pyrazino[2,3-c]-1,2,6-thiadiazine 2,2-dioxides 1N substituted pyrazino[2,3-c]-1,2,6-thiadiazine 2,2-dioxides of formula I ##STR1## where: R1 and R2, which may be the same or different, are members of the group formed by hydrogen, straight or branched chain alkyl, aryl, trifl... | 12/03/1996 |
| 5571773 | (2-imidazolin-2-yl) fused heteropyridine compounds intermediates for the preparation of and use said compounds as herbicidal agents There are provided novel (2-imidazolin-2-yl) fused heteropyridine compounds, and intermediate compounds for the preparation thereof, and a method for controlling a wide variety of annual and perennial plant species therewith.... | 11/05/1996 |
| 5510347 | Thienothiadiazine sulfonamides useful as carbonic anhydrase inhibitors New thienothiadiazine sulfonamides useful as carbonic anhydrase inhibitors are disclosed. Methods for using the compounds to control IOP are also disclosed.... | 04/23/1996 |
| 5498720 | Certain triazole compounds and their pharmaceutical uses In the invention of novel nonsteroidal antiinflammatory compounds the title novel triazole compounds, were synthesized from carboxylic acids, 2,5-acetonylacetone, or isoniazid, respectively. To give 4H-1,2,4-triazol-3-thiols. Treatment of 4H-1,2,4-tri-azo... | 03/12/1996 |
| 5476943 | Dye and heat sensitive transfer material comprising the same An image forming dye and a heat sensitive transfer material comprising the same are disclosed, the dye being represented by the following Formula (1): ##STR1##... | 12/19/1995 |
| 5472960 | Nitro-substituted heterocyclic compounds Nitro-substituted heterocyclic compounds of the formula (I) ##STR1## wherein R is hydrogen or alkyl, Z is an optionally substituted aryl or optionally substituted heterocyclic group containing at least one atom selected from N, O and S, A is optionally su... | 12/05/1995 |
| 5464831 | Thienothiadiazine sulfonamides useful as carbonic anhydrase inhibitors New thienothiadiazine sulfonamides useful as carbonic anhydrase inhibitors are disclosed. Methods for using the compounds to control IOP are also disclosed.... | 11/07/1995 |
| 5459138 | Pyridothiadiazines The invention relates to a compound selected from those of formula (I): ##STR1## in which A, R1, R2 and R4 are as defined in the description, and medicinal products containing the same which is useful for treating a p... | 10/17/1995 |
| 5411955 | Thiadiazinecarboxamide derivatives, processes for their preparation and pharmaceuticals The invention relates to thiadiazinecarboxamide derivatives of the general formula I ##STR1## to processes for their preparation, and to pharmaceuticals comprising them.... | 05/02/1995 |
| 5378704 | Non-peptidic angiotensin-II-receptor-antagonists Novel compounds having the formula ##STR1## wherein R1, R2, X and Y are as defined herein. These compounds inhibit the action of angiotensin II and are useful, therefore, for example, as antihypertensive agents.... | 01/03/1995 |
| 5356862 | Herbicidal sulfonylureas The invention relates to herbicidal sulfonylurea compounds, agriculturally suitable compositions thereof and a method for their use as general or selective preemergent or postemergent herbicides or plant growth regulants.... | 10/18/1994 |
| 5166378 | Selective monoacylation of substituted hydrazines Mono-acylated hydrazines are prepared in high yield by reaction of a hydrazine salt with an azole derivative of acyl halide in the presence of a strong base. Useful hydrazine salts include those of the formula RNHNH2 .multidot.HX, where R is al... | 11/24/1992 |
| 5017212 | Sulfonylurea compounds and herbicidal use A compound of the general formula: ##STR1## wherein Q is a condensed heterocyclic group having an N atom in the bridgehead which may be substituted, W is O or S, R1 and R2 each are an alkyl group, an alkoxy group or halogen and ... | 05/21/1991 |
| 4942143 | Imidazothiadiazine derivatives, and their use as medicaments The present invention relates to 1,3,6,7-Tetrahydro-7-oxoimidazo[4,5-c][1,2,6]-thiadiazine 2-oxide derivatives of the general formula (I): ##STR1## wherein R1, R2 and R4 are the same or different and represent an... | 07/17/1990 |
| 4891374 | Imidazo- and triazolothiadiazines Novel imidazo- and triazolothiadiazines of the general formula I ##STR1## in which R1 =C1 -C4 -alkyl, R2 =H or C1 -C3 -alkyl and the structural element --A--B--=--CH2 --CH2... | 01/02/1990 |
| 4846874 | Herbicidal sulfonamides Novel N-(heterocyclicaminocarbonyl) substituted thiophene- , furan- and pyrrolesulfonamides, such as N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-6,7-dihydro-5H-thieno- [3,2-b]thiopyran-3-sulfonamide. 4,4-dioxide and N-[(4,6-dimethoxypyrimidin-... | 07/11/1989 |
| 4838929 | Herbicidal sulfonamides Sulfonamides such as N-[(4,6-dimethoxypyrimidin-2-aminocarbonyl]-1,3-dihydro-6-methyl-3-oxofuro [3,4-c]pyridine-4-sulfonamide are useful as herbicides and plant growth regulants.... | 06/13/1989 |
| 4762550 | Herbicidal pyrazolesulfonamides This invention relates to novel pyrazolesulfonamides, agricultural compositions thereof and the methods of their use as general and/or selective herbicides and/or plant growth regulants.... | 08/09/1988 |
| 4737184 | Herbicidal sulfonamides Novel N-(heterocyclicaminocarbonyl) substituted thiophene-, furan- and pyrrolesulfonamides, such as N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-6,7-dihydro-5H-thieno- [3,2-b]thiopyran-3-sulfonamide, 4,4-dioxide and N-[(4,6-dimethoxypyrimidin-2... | 04/12/1988 |
| 4723987 | Herbicidal sulfonamides Sulfonamides such as N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-1,3-dihydro-6-methyl-3-oxof uro[3,4-c]pyridine-4-sulfonamide are useful as herbicides and plant growth regulants.... | 02/09/1988 |
| 4479946 | Phosphorus esters of amidoximes, and compositions for and methods of controlling insects using them Novel phosphorus esters of amidoximes and methods of preparing same. This invention is also directed to pesticidal compositions comprising an acceptable carrier and a pesticidally effective amount of a compound of this invention, as well as to a method of... | 10/30/1984 |
| 4443445 | Imidazo- and pyrimido-1,3,5-thiadiazin-4-ones The invention relates to novel substituted imidazo- and pyrimido-1,3,5-thiadiazin-4-ones of the formula ##STR1## wherein each of R1, R2 and R3 independently of one another is hydrogen, halogen, C1 -C4 | 04/17/1984 |
| 4361700 | Pyridopyrimidinone derivatives Derivatives of pyridopyrimidinone of the following formulae: ##STR1## wherein Y is C.dbd.S, C.dbd.O, SO2, or CH2 ; Z is C--H, N, S or O; R1 is hydrogen, hydroxyl, halogen, lower alkyl or R3 ; R2 is hydroge... | 11/30/1982 |