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Patent No. 6099319

Neuroimaging as a Marketing Tool

Neuroimaging as a means for validating whether a stimulus such as advertisement, communication, or product evokes a certain mental response such as emotion, preference, or memory, or to predict the consequences of the stimulus on later behavior such as consumption or purchasing.

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Class 540/531 - Chalcogen or nitrogen attached indirectly to the hetero ring by nonionic bonding


Subclass of Class 540 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which nitrogen or chalcogen (i.e., oxygen,
No. of patents: 95
Last issue date: 04/22/2008


1      
NumberTitleIssue Date
7361648Heterocyclylakylamines as muscarinic receptor antagonists
This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula I: wherein X, Y, and Z are O, S or NR5, and the other substituents are as defined...
04/22/2008
7279468Integrin ligands
The invention relates to novel compounds which bind to integrin receptors, their use as ligands of integrin receptors, in particular as ligands of the αvβ3 integrin receptor, their use, and pharmaceutical preparations comprising these compoun...
10/09/2007
7122677NK1 antagonists
A NK1 antagonist having the formula (I), wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5...
10/17/2006
7084092Shale hydration inhibition agent and method of use
A water-base fluid for use in drilling, cementing, workover, fracturing and abandonment of subterranean wells through a formation containing a shale which swells in the presence of water. In one illustrative embodiment, the drilling fluid includes, an aqueous based ...
08/01/2006
6992103Benzamide derivatives, processes for their preparation, and their pharmaceutical use
The present invention relates to novel hydroxyethylene compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevat...
01/31/2006
6977303Highly enantiomerically pure lactam-substituted propanoic acid derivatives and methods of making and using same
The present invention relates to highly enantiomerically pure lactam-substituted propanoic acid derivatives and methods of making and using therefor. The invention involves a multi-step synthesis to produce the lactam compounds. In one step of the reaction sequence,...
12/20/2005
6953789Thiol compounds, their production and use
The present invention provides a compound represented by Formula: wherein ring A and ring B may be same or different and each is an optionally substituted homocyclic or heterocyclic ring and the like, each R1
10/11/2005
6951959Low pressure process for manufacture of 3-dimethylaminopropylamine (DMAPA)
An improved process for the production of 3-dimethylaminopropylamine in high purity from N,N-dimethylaminopropionitrile utilizing a low pressure hydrogenation process is described. The basic process comprises contacting the nitrile with hydrogen at low pressure in t...
10/04/2005
6825188Vitronectin receptor antagonists
Compounds having a benzodiazepinyl core structure are disclosed which are vitronectin receptor antagonists useful in the treatment of osteoporosis, angiogenesis, tumor growth and metastasis, atherosclerosis, restenosis and inflammation. ...
11/30/2004
6803370Alpha amino acid derivatives—inhibitors of leukocyte adhesion mediated by VLA-4
Disclosed are certain alpha amino acid compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian...
10/12/2004
6727241Anti-inflammatory compositions and methods of use
The present invention is directed to pharmaceutical compositions containing active compounds, which inhibit the activity of the chemokines, MIP-1α and RANTES. It also is directed to methods of treating inflammatory and immunoregulatory disorders and diseases using ...
04/27/2004
6667301Heterocyclylalkylamines as muscarinic receptor antagonists
This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula I: ##STR1## wherein X, Y, and Z are O, S or NR5, and the other substituents are as defined in the specification; ...
12/23/2003
6660857Process for the preparation of &3xb5;-caprolactam
A process for the preparation of &3xb5;-caprolactam starting from 6-aminocaproic acid, 6-aminocaproamide, 6-aminocaproic ester, 6-aminocapronitrile, oligomers or polymers of these compounds or mixtures comprising at least two of these compounds, which pro...
12/09/2003
6521613Lactam compounds for penetration enhancement
Compounds, compositions and methods are disclosed useful for enhancing penetration of a pharmacologically active substances across skin or tissue membranes. Compounds for use in such compositions and methods are highly water-soluble N-substituted polyalky...
02/18/2003
6521614N-(amidinophenyl)cyclourea analogs as factor Xa inhibitors
The present application describes N-(amidinophenyl)cyclourea analogs of formula I: ##STR1## which are useful as inhibitors of factor Xa....
02/18/2003
6509359Pyrrolidin-2-one compounds and their use as neuraminidase inhibitors
A compound having the formula: ##STR1## wherein all variables are as defined in the specification, for use as a neuramninidase inhibitor....
01/21/2003
6495544Homoiminopiperidinyl hexanoic acid inhibitors of inducible nitric oxide synthase
Homoiminopiperidinyl Hexanoic Acid derivatives and pharmaceutically acceptable salts thereof useful in the inhibition of the inducible isoform of nitric oxide synthase are disclosed....
12/17/2002
6472529Retroviral protease inhibiting compounds
A compound of the formula: ##STR1## is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed....
10/29/2002
6420415Thiol compounds, their production and use
Compounds represented by general formula (1) or salts thereof which have a matrix metalloprotease inhibitory activity and are useful as drugs, wherein the rings A and B represent each an optionally substituted homocycle or heterocycle, etc.; R1...
07/16/2002
6355794Lactam derivatives for melamine impregnating resins, and resin mixtures containing them
N-Alkoxymethylactams are obtained by reacting lactams with formaldehyde and hydroxyl-containing compounds selected from diol monoethers. The substituted lactams are useful as an additive to melamne impregnating resings....
03/12/2002
6284755Inhibitors of prenyl-protein transferase
The present invention is directed to azepan-2-one compounds which inhibit prenyl-protein transferase, particularly farnesyl-protein transferase (Ftase), and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic...
09/04/2001
6262222Copolymers containing N-vinyllactam derivatives, preparation methods thereof and photoresists therefrom
Copolymers containing N-vinyllactam derivatives protected at 3-position are provided and represented by the following formula. The copolymers are used as a photoresist material suitable for deep uv process so that high sensitivity and resolution can be ob...
07/17/2001
6124333Metalloproteinase inhibitors
Therapeutically active hydroxamic acid derivatives, processes for their preparation, pharmaceutical compositions containing them, and the use of such compounds in medicine. The compounds are inhibitors of metalloproteinases involved in tissue degradation....
09/26/2000
6124332Metalloproteinase inhibitors
Therapeutically active hydroxamic acid derivatives, processes for their preparation, pharmaceutical compositions containing them, and the use of such compounds in medicine. The compounds are inhibitors of metalloproteinases involved in tissue degradation....
09/26/2000
6051678Copolymers containing N-vinyllactam derivatives, preparation methods thereof and photoresists therefrom
Copolymers containing N-vinyllactam derivatives protected at 3-position are provided and represented by the following formula. The copolymers are used as a photoresist material suitable for deep uv process so that high sensitivity and resolution can be ob...
04/18/2000
5939411Piperidine derivatives process for obtaining them and pharmaceutical compositions containing them
Piperidine derivatives, process for obtaining them and pharmaceutical compositions containing them, of formula ##STR1## used as neurokinin receptor antagonists, which are, in particular, useful for the treatment of all substance P- and neurokinin-dep...
08/17/1999
5912189Compositions containing reaction product of a cyclic compound containing both a nitrogen atom and a carbonyl group, an aldehyde or ketone, and an etheramine
The present invention is directed to a composition containing the reaction product of: (A) a cyclic compound containing a 5, 6, or 7-member ring, the ring containing at least one nitrogen and at least one carbonyl group, at least one carbonyl group being ...
06/15/1999
5869653Hydrogenation of nitriles to produce amines
An improved process for the catalytic hydrogenation of nitriles. The basic process comprises contacting the nitrile with hydrogen in the presence of a sponge or Raney cobalt catalyst under conditions for effecting conversion of the nitrile group to the pr...
02/09/1999
5856318Nitrogen-containing cyclohetero cyclo-heteroaminoaryl derivatives for CNS disorders
Certain nitrogen-containing cyclohetero cycloalkylaminoaryl compounds are described for treatment of CNS disorders such as cerebral ischemia, psychoses and convulsions. Compounds of particular interest are of the formula: ##STR1## wherein each o...
01/05/1999
5750680N-vinyllactam derivatives and polymer thereof
N-vinyllactam derivatives protected at the 3-position are provided and represented by the following formula (I). These are polymerized into homo- and copolymers for use in microlithography of semiconductor manufacture. The polymers are used as a photoresi...
05/12/1998
5693630Phenylethyl and phenylpropylamines
Compounds of the general formula ##STR1## or pharmaceutically acceptable salts thereof, wherein Z is a saturated or unsaturated 3 to 6 carbon chain, m is 2 or 3, R1 is a hydrogen atom, or a straight or branched C1-4 alkyl group,...
12/02/1997
5688944Carbamazepine derivatives
The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having the general formula ##STR1## The present invention also provides a novel carbamazepine acid compound s...
11/18/1997
5672615Arylsulfonamido-substituted hydrodxamic acids
Disclosed are the compounds of formula I ##STR1## wherein R and R1 together with the chain to which they are attached or R1 and R2 together with the carbon atom to which they are attached form a ring; pharmaceutically...
09/30/1997
5665882Pyridyl ethylation of lactams
The invention is a highly efficient synthesis for making compounds of formula: ##STR1## wherein n=0, 1, R is C1-4 alkyl or benzyl; and R1, when present, is C1-4 alkyl, OH, O--C1-4 alkyl or S--C1-4
09/09/1997
5656639Heterocyclic compounds, method of preparing them and pharmaceutical compositions in which they are present
The invention relates to compounds of the formula ##STR1## in which: m is 2 or 3; n is 0, 1 or 2; Am is ##STR2## R1 is a (C1 -C4)-alkyl or a benzyl; R2 is a substituted or unsubstituted phenyl; x is ze...
08/12/1997
5654421Automatic dishwashing compositions comprising quaternary substituted bleach activators
Automatic dishwashing detergent compositions, comprising particular quaternary-substituted bleach activators, are provided. More specifically, the invention relates to granular automatic dishwashing detergents which provide enhanced cleaning/bleaching ben...
08/05/1997
5631275Substituted benzenesulfonylureas and -thioureas, preparation processes and possible uses of pharmaceutical preparations based on these compounds
This invention relates to substituted benzenesulfonylureas and -thioureas, processes for their preparation, and uses of the pharmaceutical products based on these compounds. The substituted benzenesulfonylureas and -thioureas are of the formula I ##S...
05/20/1997
5610318Imidocarboxylic acid activators and sulfimidocarboxylic acid activators processes for their preparation and their use
This invention is directed to a process for preparing a compound containing a persalt activators and salts thereof which are derived from imidocarboxylic acids and sulfimidocarboxylic acids of the formula I: ##STR1## in which A is a group of the form...
03/11/1997
5591846Nonionic radiographic contrast agents
New nonionic radiographic contrast agents having the formula ##STR1## wherein Y is a single bond, ##STR2## R1, R1 ' and R2 are the same or different and are hydrogen, alkyl or hydroxyalkyl. Hydroxyalkyl refers to...
01/07/1997
5552419Arylsulfonamido-substituted hydroxamic acids
The invention relates to the compounds of formula I ##STR1## pharmaceutically acceptable prodrug derivatives and pharmaceutically acceptable salts thereof; methods for preparation thereof; pharmaceutical compositions comprising said compounds; and a ...
09/03/1996
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