Compounds of formula (Ia) and (Ib) wherein A is CH2, or a single bond; R2 is selected from: R, OH, OR, CO2H, CO2R, COH, COR, SO2R, CN; R6, R7 and R9 are independently selected fr...
|6906189||Catalysts and methods for catalytic oxidation|
Catalytic systems and methods for oxidizing materials in the presence of metal catalysts (preferably manganese-containing catalysts) complexed with selected macropolycyclic rigid ligands, preferably cross-bridged macropolycyclic ligands. Included are using these met...
|6686350||Cell adhesion inhibitors|
The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of us...
A compound with formula (I) ##STR1## where R10 is a therapeutically removable nitrogen protecting group; R2 and R3 are independently selected from: H, R, OH, OR, .dbd.O, .dbd.CH--R, .dbd.CH2, CH2 --CO...
|5847135||Inhibitors of interleukin-1ଲ converting enzyme|
The present invention relates to novel classes of compounds which are inhibitors of interleukin-1ଲ converting enzyme. The ICE inhibitors of this invention are characterized by specific structural and physicochemical features. This invention also rel...
|5703258||Silicon and phosphorus containing compositions|
A flame retardant organic silicon and phosphorus containing compound is produced by reacting a silicon halides compound with an organic phosphorus compound to produce an organic silicon and phosphorus halides compound which is then reacted with an organic...
|5691436||Production of silicon-phosphorus containing compositions|
A mixture of silicon and phosphorus are heated and reacted with halide to produce silicon tetrahalides, silicon-phosphorus halide and phosphorus trihalides compositions. These compositions are reacted with any suitable organic, inorganic-organic and/or in...
|5403843||Pyrrolopyrimidinyalglutaminate derivatives and their use|
A condensed pyrimidine derivative of the formula (I): ##STR1## wherein the ring A stands for an optionally substituted 5-membered ring; B stands for an optionally substituted divalent 5- or 6-membered homo- or hetero-cyclic group; X stands for, among...
|5280117||Process for the preparation of manganese bleach catalyst|
A process is described for the preparation of a manganese complex catalyst having the formula: ##STR1## wherein Mn is manganese in the +4 oxidation state; R is a C1 -C20 radical selected from the group consisting of alkyl, cyclo...
Compounds of the formula ##STR1## in which A1 and A2 independently of one another are CO--C1 -C4 alkyl, COO--C1 -C4 alkyl, CO--CF3, CO--N(R)2 or cyano; A1
The present invention relates to compounds of gallium (III) which can be given orally to achieve high serum levels of gallium (III) for the treatment of hypercalcemia of malignancy and related disorders of bone metabolism. Complexes of gallium (III) of th...
|5149699||Substituted pyridopyrimidines useful as antgiotensin II antagonists|
This invention relates to pyrrolo-, pyrido-, azepino-, and azocinopyrimidines of the general formula I ##STR1## useful for treating hypertension and congestive heart failure, to pharmaceutical compositions, and to methods for production thereof....
|4910302||Psychotropic polycyclic imides|
Compounds of the formula: ##STR1## in which Z is ##STR2## wherein X is alkylene, ethanylene or alkylidene; Q is alkylene, alkylidene, ##STR3## or Q, taken together with the carbon atoms to which it is attached forms a benzene ring...
|4886879||Process for the preparation of trifluorodichloroethyl-substituted acids and zinc compounds|
Zinc compounds of formula II CF3 CCl2 ZnCl.cndot.yL (II) wherein y is 1 or 2 and L is a solvent ligand selected from the group of the N-disubstituted acid amides, N-substituted lactams and the organic sulfoxides,...
Novel naphthyridine-, quinoline- and benzoxazine-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediate...
|4551502||Macromolecular complexes of amidocarbonylic water-soluble polymers and square platinous and equivalent organometallics|
Novel complexes are prepared from water-soluble compounds having at least one amidocarbonylic unit and a square planar organometallic compound....
|4259239||Resolution of enantiomeric complexes of nickelous chloride and alpha-aminocaprolactam|
A racemic mixture of D- and L- forms of alpha-aminocaprolactam ("ACL") dissolved in e.g. ethanol is resolved, and preferably the undesired form remaining is solution is simultaneously racemized, by forming a supersaturated solution of the D,L-(ACL)3
|4243591||Poly(vinyl phosphonomethylene amino carboxylates) and process for preparation|
Poly(vinyl phosphonomethylene amino carboxylates) having at least one N-C-P linkage and at least one carboxyl end group per molecule are prepared by reacting a polyvinyl cyclic amide, orthophosphorous acid and formaldehyde in an aqueous acidic mixture at ...
|4124584||Process of manufacturing sodium lactamoaluminates|
A process of manufacturing sodium lactamoaluminates by reacting an excess of a lactam in an aromatic hydrocarbon with at least one compound selected from sodium tetrahydridoaluminate, trisodium hexahydridoaluminate, sodium dihydrido-bis(2-methoxyethoxo)al...
|4076809||Phosphonoureide and phosphonothioureide anthelmintics|
This invention relates to novel anthelmintic compounds containing an arylene or divalent heterocyclic ring whose free valences are satisfied by 1. a disubstituted phosphoryl ureido or thioureido group and 2. an amino group or a substituted amido or thioamido group,...
|3988320||Single stage resolution/racemization of -amino-&3xb5;-caprolactam|
Resolution of -amino-&3xb5;-caprolactam with simultaneous racemization of the undesired D--amino-&3xb5;-caprolactam enantiomer is effected by forming a coordinately saturated -amino-&3xb5;-caprolactam complex with NiCl2, pr...
|3941776||Resolution/racemization of aminolactam compounds|
Resolution of -amino-&3xb5;-caprolactam with simultaneous racemization of the undesired -aminocaprolactam enantiomer is effected by preferentially crystallizing the L- (or D-) -amino-caprolactam compound in the presence of a racemizat...
|3931308||Process for conversion of lysine dihydrochloride to lysine monohydrochloride|
Lysine dihydrochloride solution, formed by the hydrolysis of .alpha.-amino-.epsilon.-caprolactam, is converted to crystalline lysine monohydrochloride by neutralization with .alpha.-amino-.epsilon.-caprolactam or a transition metal complex thereof an...