Did You Know...
...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 6953851 | Processes for preparation of 9,11-epoxy steroids and intermediates useful therein Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone and other compounds of Formula I wherein: —A—A—, —B—B—, R1, R3 | 10/11/2005 |
| 5854235 | 17-spiromethylene steroids The invention relates to a steroid derivative which steroidal skeleton is bound at carbon atom 17 to a spiromethylene ring of the formula: ##STR1## wherein Ra and Rb are independently selected from the group consisting of hydrog... | 12/29/1998 |
| 5843933 | 11ଲ-aryl-4-estrenes, process for their production as well as their use as pharmaceutical agents Compounds of formula I ##STR1## wherein X, R1, R2, R3 and R4 have the meanings indicated in the description, are described, as well as processes for their production, pharmaceutical preparations containing ... | 12/01/1998 |
| 5741786 | Steroids with a 17-spiromethylene lactone or lactol group A steroid with a 17-spiromethylene lactone group having formula I ##STR1## wherein R1 is O, (H,H), (H,OR), or NOR, R being selected from H, (1-6C) alkyl and (1-6C) acyl; R2 is H, (1-6C) alkyl optionally substituted by a halogen,... | 04/21/1998 |
| 5712264 | 17-spiromethylene steroids The invention relates to a steroid derivative which steroidal skeleton is bound at carbon atom 17 to a spiromethylene ring of the formula: ##STR1## wherein Ra and Rb are independently selected from the group consisting of hydrog... | 01/27/1998 |
| 5426102 | 14ଲ-H-, 14-and 15-En-11ଲ-aryl-4-oestrenes Novel compounds of the general formula I ##STR1## and the pharmacologically tolerable addition salts thereof with acids are described, in which either Ia) R11 represents a hydrogen atom in the ଲ-configuration and each of R12 | 06/20/1995 |
| 5319115 | Method for making 3-hydroxy, 3ଲ-substituted-pregnanes This invention provides a simplified method for converting pregnan-3,20-dione compounds to 3-hydroxy,3ଲ-substituted-pregnanes. By selective use of reagents the unprotected dione is converted chemoselectively and diastereoselectively into... | 06/07/1994 |
| 5292878 | 17-spirofuran-3'-ylidene steroids The invention relates to an antiprogestin 17- spirofuran-3'-ylidene steroid having the formula ##STR1## p0 R1 is NR2 R3, lower acyl, OH, SH, O-lower alkyl or S(O)n -lower alkyl wherein n is 0-2; R2 | 03/08/1994 |
| 5218110 | 4-amino-Ɗ4 -steroids and their use as 5-reductase inhibitors The present invention relates to 4-azido-Ɗ4 -steroids which are useful as inhibitors of 5-reductase. The compounds are prepared by the reaction of an appropriate 4-azido steroid with triphenylphosphine in an aqueous inert solvent with h... | 06/08/1993 |
| 5189032 | 4-amino-Ɗ4,6 -steroids and their use as 5-reductase inhibitors The present invention relates to 4-amino-Ɗ4,6 -steroids which are useful as inhibitors of 5-reductase. The compounds are prepared by the reaction of an appropriate 4,5-epoxy steroid with sodium azide in an inert solvent in the presence ... | 02/23/1993 |
| 5182381 | Intermediates for 3-keto-19-nor-Ɗ4,9 -steroids Novel 3-keto-19-nor-Ɗ4,9 -steroids of the formula ##STR1## and their non-toxic, pharmaceutically acceptable acid addition salts possessing a remarkable antiglucocorticoidal activity.... | 01/26/1993 |
| 5130424 | 4-amino-delta-4,6-steroids and their use as 5 alpha-reductase inhibitors The present invention relates to 4-amino-Ɗ4,6 -steroids which are useful as inhibitors of 5-reductase. The compounds are prepared by the reaction of an appropriate 4,5-epoxy steroid with sodium azide in an inert solvent in the presence ... | 07/14/1992 |
| 5120840 | 4-amino-4-ene-steroids and their use as 5-reductase inhibitors The present invention relates to 4-amino-Ɗ4 -steroids which are useful as inhibitors of 5-reductase. The compounds are prepared by the reaction of an appropriate 4-azido steroid with triphenylphosphine in an aqueous inert solvent with h... | 06/09/1992 |
| 4987128 | Novel 10ଲ-alkynyl-steroids Novel 10ଲ-alkynyl-steroids of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, optionally substituted alkyl and alkoxy of 1 to 8 carbon atoms, optionally substituted alkenyl and alkynyl of 2 to 8 carbon atoms, o... | 01/22/1991 |
| 4954446 | Aromatic steroid 5--reductase inhibitors Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutial compositions containing the compounds, and methods of using these compounds to inhibit steroid 5--reductase including using these compounds to reduce prosta... | 09/04/1990 |
| 4891365 | 17-Substituted estradienes and estratrienes 17-Substituted estradienes and estratrienes of Formula I ##STR1## wherein ##STR2## R is alkyl, alkenyl or cycloalkyl of up to 5 carbon atoms if ##STR3## R is hydrogen, alkyl, alkenyl or cycloalkyl of up to 5 carbon atoms if ##STR4## ... | 01/02/1990 |
| 4501695 | Spironalactone process The present invention relates to processes for the conversion of a 3-protected steroidal 17-ketone to a 17-spiro-γ-lactone having the appropriate 17-stereochemistry for spironolactone. Novel intermediates (II, II', II", II'", IIa, IIb | 02/26/1985 |
| 4477445 | 3-Keto-19-nor-Ɗ4,9-steroids Novel 3-keto-19-nor-Ɗ4,9-steroids of the formula ##STR1##... | 10/16/1984 |
| 4297350 | Male contraceptive steroids and methods of use The steroids of the present invention have been found to be useful as male contraceptives when administered orally. Upon cessation of administration of the male contraceptive steroids of the present invention the male promptly regains normal fertility.... | 10/27/1981 |
| 4243586 | Steroidal-17-spiro-dihydrofuranones Steroidal-17-spiro-dihydrofuranones, i.e., steroid having in the 17-position a group having the partial structural formula ##STR1## wherein R1 is bromine, chlorine, or fluorine; R2 is alkyl, aryl, or arylalkyl; R3 is ... | 01/06/1981 |
| 4192802 | Process for the manufacture of steroid carboxylic acid lactones An advantageous method for the manufacture of steroidal lactones of the spironolactone and canrenone type involves the following reaction sequence: bromination of a 3ଲ ,17-dihydroxy-17 -pregn-5-en-21-carboxaldehyde in basic or neutral medium,... | 03/11/1980 |
| 4150127 | Novel steroid compounds having an oxygen function in the 19-position Novel 19-oxygenated steroids of the 20-spiroxane series of the formula ##STR1## in which R3 is a lower alkyl radical carrying an oxygen-containing functional group and R4 is two hydrogen atoms or an oxo group, and which carry a ... | 04/17/1979 |
| 4146538 | 17-Alkylthio (and arylthio) androsteno[17,16-b]benzopyran-3-ones and [16,17]naphthopyran-3-ones Steroids having the formula ##STR1## wherein X is -S-, ##STR2## R1 is alkyl, aryl or acyloxyalkyl; R2 is carbonyl or ଲ-hydroxymethylene; R3 is hydrogen or halogen; R4 is hydrogen, fluorine o... | 03/27/1979 |
| 4119627 | Process for the manufacture of 6ଲ,7-methylene-3-oxo-4-ene steroids The invention provides a novel general process for the manufacture of 6ଲ,7-methylene-3-oxo-4-ene-steroids by successively (a) reacting a 3.xi.,5ଲ-dihydroxy-6-ene-steroid which is optionally etherified or esterified in the 3-position with a zin... | 10/10/1978 |
| 4079054 | 7-Halogeno-3-oxo-1,4-pregnadiene-21,17ଲ-carbolactones and related compounds Described are 3-oxo-7-halogeno-17-1,4-pregnadiene-21,17ଲ-carbolactone s and compounds related thereto, i.e. 2',3'-tetrahydrofuran-2'-spiro-17(7-halogeno-1,4-androstadie ne-3-ones) and (17R)-spiro-[7-halogen... | 03/14/1978 |
| 4076708 | Process for the preparation of 7-halogeno-3-oxo-4-dehydro steroids and novel 7-halogeno derivatives produced thereby 3-Oxo-6-unsubstituted-7-halogeno-4-dehydro steroids, wherein said halogen is chlorine, bromine or iodine, are prepared by reaction of a 3-oxo-6,7-di-unsubstituted-4,6-bis-dehydro steroid with at least an equimolar quantity of the corresponding hydr... | 02/28/1978 |
| 4054563 | Process for the manufacture of spiro compounds of the steroid series Compounds of the general formula ##STR1## wherein R1 represents a hydrogen atom or a lower alkyl group, which contain a double bond in 5-position and a methyl group in 10-position, or three double bonds in the position 1,3 and 5)10), and w... | 10/18/1977 |
| 3939155 | 4',5'-Dihydrospiro[androst/estr-4-ene-17,2'(3'H)-furan]3,4'-dione and congeners, and intermediates thereto 4',5'-Dihydrospiro[androst/estr-4-ene-17,2'(3'H)-furan]-3,4'-dione and congeners; the antiviral, antiandro genic, diuretic, and/or antiestrogenic activity inherent therein; and means of preparing them via novel intermediates are disclosed.... | 02/17/1976 |
