Bizarre Patents
Decorative Jeweled Wheel Cover
An improved wheel is provided wherein decorative items such as gem stones are embedded in either the wheel surface, a special mounting section attached to the wheel surface, or to a spoke strap that wraps around each spoke and positions embedded gem stones on the outside surface of the spoke.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8178665 | Process for the production of ezetimibe and intermediates used in this process A process for the production of 1-(4-3(R)-[3(S)-(4-fluorophenyl)-3-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone (ezetimibe) according to the following reaction scheme: (I), (II), (III), (IV), (V), (VI), (VII), (VIII), (IX), (X), (XI) where the substances of t... | 05/15/2012 |
| 8013150 | Process for the preparation of ezetimibe The present invention relates to a cost effective and industrially advantageous process for the preparation of (3R,4S)-1-(4-fluorophenyl)-3-[3(S)-3-(4-fluorophenyl)-3-hydroxypropyl)]-4-(4-hydroxyphenyl)-2-azetidinone, referred to here as Ezetimibe and represented by... | 09/06/2011 |
| 7956182 | Process for preparing optically active alcohols This invention relates to a process for producing optically active alcohols using asymmetric reduction of aromatic ketones. This process gives optically active alcohols in high enantioselectivity in a large scale production. ... | 06/07/2011 |
| 7879997 | Compounds for the treatment of inflammatory disorders This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, wherein n, M, V, T, W, X, U, R1 and R2 are as disclosed in the present specific... | 02/01/2011 |
| 7879998 | 4-alkenyl-2-azetidinone derivatives, process for preparing 4-alkenyl-2-azetidinone derivatives and multicyclic compounds prepared using 4-alkenyl-2-azetidinone derivatives The present invention relates to 4-alkenyl-2-azetidinone derivatives, a process for preparing 4-alkenyl-2-azetidinone derivatives and multicyclic compounds prepared using 4-alkenyl-2-azetidinone derivatives. More specifically, the present invention relates to a 4-al... | 02/01/2011 |
| 7772392 | Therapeutic substituted β-lactams Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof; wherein a dashed line indicates the presence or absence of a bond; Y is an organic ... | 08/10/2010 |
| 7576200 | Diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics. | 08/18/2009 |
| 7563888 | Process for the preparation of diphenyl azetidinone derivatives The present invention is a process for the preparation of diphenylazetidinone derivatives of the formula (I) or forms thereof comprising the substituents X, R1 and/or R2 as defined herein. More specifically, the invention comprises methods for ... | 07/21/2009 |
| 7541458 | β-lactam synthesis The present invention is directed to a process for the preparation of β-lactams. Generally, an imine is cyclocondensed with a ketene acetal or enolate to form the β-lactam product in a “one pot” synthesis, this process is generally performed at a higher temper... | 06/02/2009 |
| 7538212 | Intermediate for carbapenem compound for oral administration and process for producing the same The present invention provides a novel intermediate represented by formula (1), (3), or (4) for efficiently producing a 1β-methylcarbapenem compound for oral administration, and a process for producing the intermediate. That is, the present invention provides a pro... | 05/26/2009 |
| 7524951 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof The present invention relates to compounds represented by formula (1) and a process for producing the same. The use of these compounds can realize the production of carbapenem derivatives having potent antimicrobial activity and a wide antimicrobial spectrum in a sa... | 04/28/2009 |
| 7498431 | Process for the preparation of chiral azetidinones Processes for preparing compounds of formula I are disclosed comprising the steps of: (a) forming of chiral propionic acid ester compounds of formula V. (b) reacting compounds of ... | 03/03/2009 |
| 7488818 | Method for producing 1,4-diphenyl azetidinone derivatives The present invention is directed to the preparation of novel compounds useful in the treatment of hyperlipidemia, arteriosclerosis, hypercholesterolemia, and other related metabolic disorders. More specifically, the present invention is a novel process for the prep... | 02/10/2009 |
| 7482445 | Crystalline carbapenem intermediate This invention relates to crystals of compounds of formula (I), wherein TBS represents t-butyldimethylsilyl, and Ph represents phenyl, or its salt or solvate. Compounds of formula (I) are synthesis intermediates of 2-substituted-1β-methyl carbapenem compounds usefu... | 01/27/2009 |
| 7435727 | Method for isolating an intestinal cholesterol binding protein The invention describes a method for isolating an intestinal protein which is able to bind cholesterol and/or cholesterol uptake inhibitors. Methods of identifying inhibitors of cholesterol uptake and related pharmaceuticals and methods of treatment also are describ... | 10/14/2008 |
| 7407938 | Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use One embodiment of the invention relates to compounds of the formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable... | 08/05/2008 |
| 7388004 | Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use One embodiment of the invention relates to compounds of the formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable... | 06/17/2008 |
| RE40183 | 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines The invention is drawn to 7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline compounds of the formula wherein R, X, R5 and R6 are defined in the specification. The compounds of the invention ... | 03/25/2008 |
| 7339055 | Process for the preparation of cephalosporin antibiotic A process for the preparation of cephalosporin antibiotic of the formula (I) which comprises: (i) activating the compound of formula (III) as acid halide in an organic solvent | 03/04/2008 |
| 7320972 | 4-Biarylyl-1-phenylazetidin-2-ones 4-Biarylyl-1-phenylazetidin-2-ones useful for the treatment of hypercholesterolemia are disclosed. The compounds are of the general formula in which represen... | 01/22/2008 |
| 7285674 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules The present invention provides a silane molecule which combines pre-activated and protein-resistant functionalities in one molecule; the molecule has a general formula: A-(CH2)n—(O[CH2]t)m—(CH... | 10/23/2007 |
| 7273933 | Methods for synthesis of oligonucleotides Improved methods for synthesis of oligonucleotides and other phosphorus-linked oligomers are disclosed. The methods include the use of aromatic solvents, alkyl aromatic solvents, halogenated aromatic solvents, halogenated alkyl aromatic solvents, or aromatic ether s... | 09/25/2007 |
| 7265106 | Method for isolating ()-tofisopam (R)-tofisopam, substantially free of the (S)-enantiomer of tofisopam, is obtained by separating the enantiomers of tofisopam by chromatography employing a chiral separation medium comprising (i) (2S)-2-{(1S)[(3,5-dinitrophenyl)carbonylamino]phenylmethyl}-3,3-dimethy... | 09/04/2007 |
| 7235543 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof The present invention provides compounds represented by the structural formula (I): or pharmaceutically acceptable isomers, salts, solvates or esters of the compound of Formula (I), wherein each of the substituen... | 06/26/2007 |
| 7226661 | Synthesis of quinones and phenols on solid support Generally, and in one form, the present invention is a method of making a benzene-modified compound on solid support that includes the steps of forming an (oxy)(aryl)carbene complex, esterifying the (oxy)(aryl)carbene complex to form an (ester)(aryl)carbene complex,... | 06/05/2007 |
| 7227017 | Process for the preparation of phosphorothioate oligonucleotides A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an oligonucleotide bound to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitril... | 06/05/2007 |
| 7223859 | Method for producing (R)-3-[4-(trifluoromethyl) phenylamino]-pentanoic acid amide derivative The present invention provides a method for easily producing an (R)-3-[4-(trifluoromethyl)phenylamino]-pentanoic acid amide derivative useful for an intermediate for pharmaceutical products, particularly an inhibitor of a cholesteryl ester transfer protein (CETP) fr... | 05/29/2007 |
| 7220870 | Hydrolytic kinetic resolution of cyclic substrates The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisome... | 05/22/2007 |
| 7214364 | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, ... | 05/08/2007 |
| 7208486 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof The present invention provides compounds represented by the structural formula (I): or pharmaceutically acceptable isomers, salts, solvates or esters of the compound of Formula (I), wherein each of the substituen... | 04/24/2007 |
| 7205290 | Diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic. ... | 04/17/2007 |
| 7192944 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof The present invention provides compounds represented by the structural formula (I): or pharmaceutically acceptable isomers, salts, solvates or esters of the compound of Formula (I), wherein each of the substituen... | 03/20/2007 |
| 7176193 | Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use One embodiment of the invention relates to compounds of the formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically... | 02/13/2007 |
| 7176194 | Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use One embodiment of the invention relates to compounds of the formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically... | 02/13/2007 |
| 7135556 | NPC1L1 (NPC3) and methods of use thereof We claim an isolated polypeptide having ability of binding with cholesterol. Said polypeptide is useful for investigating regulation of intestinal cholesterol absorption and cholesterol levels. Also, we claim a composition comprising said polypeptide bound to choles... | 11/14/2006 |
| 7115595 | Carbapenem compounds Carbapenem compounds having a substituted phenyl or a substituted thienyl directly attached to the 3-position of carbapenem nucleus as represented by the formula: wherein Ring E is benzene ring or thiophen... | 10/03/2006 |
| 7112670 | Crystal form The present invention involves a novel crystal form of 17β-hydroxy-7α-(5′-methyl-2′-furyl)-pregna-4,9(11)-dien-3-one-21-carboxylic acid, γ-lactone, having the formula which is an intermediate useful in pre... | 09/26/2006 |
| 7109343 | Metal catalysts and methods for making and using same Compounds having the formula: are disclosed. M1 and M2 are the same or different and are transition metal atoms or ions; Z2 and Z3, independently, are the atoms necessa... | 09/19/2006 |
| 7090775 | Separation agent for separating optical isomer and method for preparation thereof A method of producing a novel separating agent for separating enantiomeric isomers, characterized by including: a step of supporting an optically active polymer compound and a compound having an asymmetric structure of a molecular weight of 1,000 or less on a carrie... | 08/15/2006 |
| 7087548 | Preparation and use of a heterogeneous rhodium catalyst for the hydrogenation of a double bond of an α-β-unsaturated carbonyl compound A process for preparing an Rh-based catalytic system heterogenized on an organic or mineral support, characterized in that: a) a rhodium derivative with a valency state>0 is reduced in an ether or aromatic solvent and in the presence of a compound chosen from the gr... | 08/08/2006 |
