Quotables
"The wireless music box has no imaginable commercial value. Who would pay for a message sent to nobody in particular?"
David Sarnoff, American radio pioneer ; 1921
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7074778 | Asthma associated factors as targets for treating atopic allergies including asthma and related disorders This invention relates to methods for treating asthma or allergy in a mammal by administering a 3-aminosteroid compound to a mammal in need thereof. The 3-aminosteroid compound being capable of down regulating the IL-9 pathway and alleviating asthmatic responses to ... | 07/11/2006 |
| 6784170 | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one Syntheses of steroids such as 3-hydroxy-7α-methyl-21-[2′-methoxy-4′-(diethylaminomethyl)-phenoxy]-19-norpregna-1,3,5(10)triene citrate (“SR 16234”) and analogs thereof are provided, wherein 21-hydroxy-19-norpregna-4-en-3-one serves as a starting material or... | 08/31/2004 |
| 6670348 | Methods and compositions for destruction of selected proteins Compounds having an ansamycin anitibiotic, or other moiety which binds to hsp90, coupled to a targeting moiety which binds specifically to a protein, receptor or marker can provide effective targeted delivery of the ansamycin antibiotic leading to the deg... | 12/30/2003 |
| 6537983 | Anti-inflammatory androstane derivatives According to one aspect of the invention, there is provided a pharmaceutical formulation for administration by inhalation comprising a compound of formula (I), ##STR1## wherein R1 represents C1-6 alkyl or C1-6 haloalkyl; R... | 03/25/2003 |
| 6436917 | Non-estrogenic estradiol derivative compounds with anti-oxidative activity New non-estrogenic derivative compounds of estradiol, which have no estrogenic activity and comparatively high anti-oxidative activity, are disclosed. These new non-estrogenic derivative compounds are potentially useful as non-estrogenic antioxidants, esp... | 08/20/2002 |
| 6437157 | 20-substituted steroids A compound selected from the group consisting of a compound of the formula ##STR1## wherein R1 and R2 are individually selected from the group consisting of alkyl of 1 to 12 carbon atoms and aralkyl of 7 to 15 carbon atoms or taken t... | 08/20/2002 |
| 6281205 | Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5(10)-estratriene nucleus, and are substituted at the C-17 or C-11 position with a mol... | 08/28/2001 |
| 6180618 | Propanolamine derivatives linked to bile acids, processes for their preparation, pharmaceuticals comprising these compounds, and their use Compounds of formula (I) ##STR1## in which the radicals are as defined in the specification and claims, and physiologically tolerated and physiologically functional derivatives thereof and processes for their preparation are described. The compounds ... | 01/30/2001 |
| 6054446 | Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecul... | 04/25/2000 |
| 5792759 | 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl cyclopentaneperhydrophenanthrene derivatives active on the cardiovascular system, a process for their preparation and pharmaceutical compositions containing the same Novel 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl steroids of the general formula (I) ##STR1## where A, R1 and R2 are defined in the specification are disclosed. The compounds have cardiovascular activity. Pharmaceutic... | 08/11/1998 |
| 5760214 | Bone resorption inhibition/osteogenesis promotion compound A compound represented by the following formula (I): X--Y--Z (I) where Y is represented by the following formula (III): ##STR1## X is a monovalent group of a tetracycline type compound, and Z is a monov... | 06/02/1998 |
| 5646316 | Bile acid inhibitors of metalloproteinase enzymes The present invention relates to a bile acid derivative, which comprises a bile acid derivatized at the carboxyl group with a hydroxamic acid or hydroxamate ester. The carboxyl group in the bile acid compound can also be derivatized with an amino acid or ... | 07/08/1997 |
| 5608093 | Corticosteroid 17-alkyl carbonate 21-[0]-carboxylic and carbonic esters, and pharmaceuticals containing these compounds Corticoid 17-alkyl carbonate 21-carboxylic and carbonic esters of the formula I ##STR1## are described in which A is CHOH and CHCl, CH2, C.dbd.O or 9(11) double bond; Y is H, F or Cl; Z is H, F or CH3 ; R(1) is aryl or heta... | 03/04/1997 |
| 5599806 | Hydrazino and hydroxyamino-14-ଲ-hydroxyandrostane derivatives active on the cardiovascular system processes for their preparation and pharmaceutical compositions containing same The invention describes hydrazino and hydroxyamino-14ଲ-hydroxyandrostane derivatives having general formula (I): ##STR1## wherein the symbol means or ଲ configuration and A, B, R1, R2, R3, and... | 02/04/1997 |
| 5591733 | Methods, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, insomnia and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-aminobutyric acid receptor-chloride ionoph... | 01/07/1997 |
| 5583127 | 17-iminomethylalkenyl-5 ଲ, 14 ଲ-androstane and 17-iminoalkyl-5 ଲ, 14 ଲ-androstane derivatives active on the cardiovascular system, and pharmaceutical compositions containing same Disclosed are 17-iminomethylalkenyl and 17-iminoalkyl-14ଲ-hydroxy-5ଲ-androstane derivatives of the formula (I): ##STR1## wherein the symbol means or ଲ configuration or a Z or E configuration; A represents (CH2 | 12/10/1996 |
| 5449795 | Process for synthesis of steroidal allylic tert. alcohols A method for the preparation of a steroidal allylic tertiary alcohol is disclosed which involves the deprotonation of a sulfoxide with a strong base which is capable of deprotonating the methine proton which is to the sulfoxide, in an inert solven... | 09/12/1995 |
| 5334712 | Cyclic hydrocarbons with an aminoalkyl sidechain Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.... | 08/02/1994 |
| 5274089 | Cyclic hydrocarbons with an aminoalkyl sidechain Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.... | 12/28/1993 |
| 5232917 | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, insomnia and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-aminobutyric acid receptor-chloride ionoph... | 08/03/1993 |
| 5208227 | Method, compositions, and compounds for modulating brain excitability Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-ammobutyric acid/benzodiazepine receptor-chloride i... | 05/04/1993 |
| 5120723 | Method, compositions, and compounds for modulating brain excitability Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-ammobutyric acid/benzodiazepine receptor-chloride i... | 06/09/1992 |
| 5075434 | Antidiabetic 3-halo-ଲ-aminoestranes This invention is a compound of formula 1 and pharmaceutically acceptable salts thereof; ##STR1## wherein R1 is fluorine, chlorine or bromine; wherein R2 is hydrogen or (C1 -C3) alkyl; wherein n is one or 2... | 12/24/1991 |
| 4560557 | Silicon and sulfur steroids as irreversible inhibitors of hormone biosynthesis The compounds of the present invention are irreversible and highly selective inhibitors of the cytochrome P-450 cholesterol side chain cleavage (P-450scc) enzyme responsible for the first and rate limiting step of steroid hormone biosynthesis by the adren... | 12/24/1985 |
| 4560512 | Derivatives of steroid compounds linked to cyotoxic agents The present application is concerned with compounds useful as carriers of cytotoxic agents. More particularly it deals with derivatives of steroid compounds having a 5-androstene carbon skeleton and having an oleyl ester at the 3-position and having a 17-... | 12/24/1985 |
| 4412955 | Preparation of corticoids from 17-keto steroids Disclosed is a 20,21-dihalo steroid (VII) and a steroidal sulfoxide (VIII) as well as processes to produce them. The 20,21-dihalo steroid (VII) and sulfoxide (VIII) are intermediates useful in the preparation of pharmaceutically useful corticoids.... | 11/01/1983 |
| 4411835 | Preparation of corticoids from 17-keto steroids The present invention is a process for the transformation of a 17-keto steroid (II) to a corticoid (XI) which has pharmaceutical utility.... | 10/25/1983 |
| 4404142 | Preparation of corticoids from 17-keto steroids A process for the preparation of corticoids (XI) which comprises reacting a protected 17-keto steroid (II) with a metallated 1,2-dihaloethene (III).... | 09/13/1983 |
| 4390530 | 3-Deoxy-Ɗ15 -steroids 3-Deoxy-Ɗ15 -steroids of the formula ##STR1## wherein R1 is hydrogen or an acyl group of a C1-15 hydrocarbon carboxylic acid, and R2 is ethynyl, chloroethynyl or propynyl are valuable progestationally effe... | 06/28/1983 |
| 4360663 | Steroid hormone-antitumor derivatives A process for producing a steroid hormone-antitumor derivative which selectively affects to tumor or cancer cells comprises reacting X group of a steroid hormone derivative having the formula ##STR1## wherein ST represents a steroid moiety having a c... | 11/23/1982 |
| 4242334 | Corticoid 17-(alkyl carbonates) and processes for their preparation What is disclosed is corticoid 17-(alkyl carbonates) of the formula ##STR1## as defined in the specification, which compounds can be used in veterinary therapy and human therapy, in the form of suspensions, ointments, creams, sprays and the like, for... | 12/30/1980 |
| 4192871 | Chemical compounds Pregnanes and androstanes are described which essentially possess a 3-hydroxy group, a 5-hydrogen atom or a 4.5- or 5,6-double bond, a 17-hydrogen atom and an 11ଲ-aminoester group. Other optional substituents or double bonds may... | 03/11/1980 |
| 4181669 | Steroid esters preparation This invention relates to an improved steroid ester synthesis in which a carbodiimide, in combination with an acid catalyst, is used as condensing agent.... | 01/01/1980 |
| 4180570 | 17ଲ-Hydroxy-4-androsten-3-ones and process for the preparation thereof Compounds of the formula I ##STR1## wherein R2 is hydrogen or an organic acid residue; R3 is methyl or ethyl; R4 is hydrogen or methyl; ##STR2## wherein R1 is lower alkyl; and ##STR3## and when ... | 12/25/1979 |
| 4081537 | Ɗ15 -Steroids and pharmaceutical compositions thereof Ɗ15 -Steroids of the formula ##STR1## wherein R1 is a hydrogen atom, trialkylsilyl or acyl; R2 is ethynyl, chloroethynyl or propinyl; and X is an oxygen atom, ##STR2## or NOR4 wherein R3 is... | 03/28/1978 |
| 4041055 | Process for the preparation of 17-hydroxyprogesterones and corticoids from androstenes This invention discloses a general process for the production of corticoids from androstenes. This invention provides an economically viable alternative synthesis of 17-hydroxyprogesterones and the corticoids.... | 08/09/1977 |
| 4011314 | 7-Hydroxyestradiols 7-Hydroxyestradiols of the formula ##STR1## wherein R1 is hydrogen, acyl, alkyl, cycloalkyl, an oxygenated saturated heterocyclic group or hydrocarbylsulfonyl; R2 and R3 each are hydrogen, acyl, oxygenated saturated h... | 03/08/1977 |
| 3969345 | 20ଲ,21-Epoxy-3-hydroxy-5-pregnanes and derivatives thereof The invention provides 3-oxygenated pregnane 21-ethers possessing a hydroxy group in the 3-position; a hydrogen atom or a methyl group at the 10-position; a hydrogen atom in the 17-position; a keto group in the 20-position; and an eth... | 07/13/1976 |
