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Class 540/104 - Nitrogen or sulfur attached directly or indirectly to the cyclopentanohydrophenanthrene ring system by nonionic bonding


Subclass of Class 540 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which nitrogen or sulfur is attached directly
No. of patents: 18
Last issue date: 07/17/2001


NumberTitleIssue Date
626204217ଲ-amino and hydroxylamino-11ଲ-arylsteroids and their derivatives having agonist or antagonist hormonal properties
The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity....
07/17/2001
559173417-(3-furyl)-5ଲ, 14ଲ-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same
The present invention relates to a group of 17-(3-furyl)- and (4-pyridazinyl) 5ଲ,14ଲ-androstane derivatives, active on the cardiovascular system, to processes for their preparation and to pharmaceutical compositions containing same for the tre...
01/07/1997
5478817Digitoxigenin and dihydrodigitoxigenin 3ଲ-derivatives and pharmaceutical compositions comprising same for the treatment of cardiovascular disorders
Digitoxigenin and dihydrodigitoxigenin 3ଲ-derivatives, a process for their preparation and pharmaceutical compositions containing same for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed....
12/26/1995
5198537Digoxigenin derivatives and use thereof
The present invention provides digoxigenin derivatives of the formula: ##STR1## wherein n is a whole number of from 1 to 4 and Z is a carboxyl group or a functional derivative derived therefrom. The present invention also provides digoxigenin conjuga...
03/30/1993
4469797Digoxigenin immunogens, antibodies, labeled conjugates, and related derivatives
Immunogen conjugates comprising N-substituted-amino-3-desoxydigoxigenin derivatives coupled to conventional immunogenic carrier materials, and antibodies raised against such conjugates. Also provided are labeled digoxigenin conjugates for use with the dig...
09/04/1984
4323500Method for preparing 7଱-acylthio-4-en-3-oxosteroids
A 7଱-acylthio-4-en-3-oxosteroid such as 7଱-acetylthio-17-hydroxy-3-oxo-17଱-pregn-4-ene-21-carboxylic acid γ-lactone (spironolactone) which is an antialdosteronic diuretic effective in therapy is prepared by contacting a steroidal m...
04/06/1982
4219549Amino-3 cardenolides, process for preparation, and pharmaceutical compositions containing same
Aminocardenolides of formula (I): ##STR1## in which R1, R2, R4, R5, and R6, which may be the same or different, each represents a hydrogen atom or a hydroxy, alkoxy or acyloxy group; R3
08/26/1980
4218447Acyl derivatives of hellebrigenin
There are prepared compounds corresponding to the general formula: ##STR1## in which R represents a 2,2-dimethylethenyl; isopropyl; nonyl; a C3 -C6 -cycloalkyl radical; a phenyl group substituted by at least one nitro group, or ...
08/19/1980
4217280Amino-3-cardenolide derivatives, process for their preparation, and pharmaceutical compositions containing same
Amino-3-cardenolide derivatives represented by the general formula (I) ##STR1## wherein n and m, which may be the same or different, each represents an integer from 0 to 4; R1, R2, R4, R5 and R6, whic...
08/12/1980
4175078Cardenolide and bufadienolide derivatives of ajmaline and process for producing same
According to the invention, the novel substances are the cardenolide and adienolide derivatives of ajmaline of the general formula ##STR1## wherein R is cardenolide or bufadienolide of the general formula ##STR2## Z is an unsaturated five-membe...
11/20/1979
4115539Analytical or clinical derivatives, tagged derivatives and methods of analysis using such derivatives
Novel isocyanates such as, for example, blocked L-tyrosine methyl ester isocyanate, are reacted with compounds of biological, clinical interest or the like such as, for example, digoxin, to form derivatives receptive to tagging, as by radiolabeling. The t...
09/19/1978
410288414 ଲ-Hydroxy 3-deoxycardenolides
Novel compounds of the formula ##STR1## useful as pharmaceutical compounds are disclosed. Processes are also disclosed for their preparation....
07/25/1978
4082747Chemical process
An improved process for coupling an amino acid or derivative thereof to a cardiotonic glycoside derivative....
04/04/1978
4060607Cardenolide derivatives
Cardiotonic cardenolide derivatives of the formula ##STR1## wherein n, m, R1 to R9 are as hereinafter defined, the mineral or organic salts thereof and a process for their preparation....
11/29/1977
4030886Saturation analysis
The invention provides a method and a kit for the saturation analysis of a steroid characterized by the use of a selenium-75 labelled version of the steroid to be assayed. Selenium-75 derivatives of steroids are quite simple to prepare and have practical ...
06/21/1977
4000125Novel cardiotonic steroids, process for their preparation and therapeutical use
The invention relates to novel steroid compounds having the formula ##STR1## and their glycoside derivatives containing a pyridazine ring, in which particularly the substituent R4 is a hydroxy group or a hexopyranoside unit or a chain of t...
12/28/1976
3981982Radioimmunoassay for determining the digoxin content of a sample
A competitive radioimmunoassay for the measurement of digoxin in a serum sample in which the non-radioactive digoxin competes with a constant amount of a radioactively labeled digoxin tyramine analog comprising 3-O-(4-Hydroxyphenethylcarbamoyl) digoxigeni...
09/21/1976
3954739Biological reagent
Compounds of formula (VIII) wherein R1, r2, r3, r4 and R5 are each selected from hydrogen and an hydroxyl group and at least four are hydrogen; B is an alkylene chain of from 1 to 4 carbon atoms; R is selected ...
05/04/1976
 
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