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| Number | Title | Issue Date |
| 6262042 | 17ଲ-amino and hydroxylamino-11ଲ-arylsteroids and their derivatives having agonist or antagonist hormonal properties The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.... | 07/17/2001 |
| 5591734 | 17-(3-furyl)-5ଲ, 14ଲ-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same The present invention relates to a group of 17-(3-furyl)- and (4-pyridazinyl) 5ଲ,14ଲ-androstane derivatives, active on the cardiovascular system, to processes for their preparation and to pharmaceutical compositions containing same for the tre... | 01/07/1997 |
| 5478817 | Digitoxigenin and dihydrodigitoxigenin 3ଲ-derivatives and pharmaceutical compositions comprising same for the treatment of cardiovascular disorders Digitoxigenin and dihydrodigitoxigenin 3ଲ-derivatives, a process for their preparation and pharmaceutical compositions containing same for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed.... | 12/26/1995 |
| 5198537 | Digoxigenin derivatives and use thereof The present invention provides digoxigenin derivatives of the formula: ##STR1## wherein n is a whole number of from 1 to 4 and Z is a carboxyl group or a functional derivative derived therefrom. The present invention also provides digoxigenin conjuga... | 03/30/1993 |
| 4469797 | Digoxigenin immunogens, antibodies, labeled conjugates, and related derivatives Immunogen conjugates comprising N-substituted-amino-3-desoxydigoxigenin derivatives coupled to conventional immunogenic carrier materials, and antibodies raised against such conjugates. Also provided are labeled digoxigenin conjugates for use with the dig... | 09/04/1984 |
| 4323500 | Method for preparing 7-acylthio-4-en-3-oxosteroids A 7-acylthio-4-en-3-oxosteroid such as 7-acetylthio-17-hydroxy-3-oxo-17-pregn-4-ene-21-carboxylic acid γ-lactone (spironolactone) which is an antialdosteronic diuretic effective in therapy is prepared by contacting a steroidal m... | 04/06/1982 |
| 4219549 | Amino-3 cardenolides, process for preparation, and pharmaceutical compositions containing same Aminocardenolides of formula (I): ##STR1## in which R1, R2, R4, R5, and R6, which may be the same or different, each represents a hydrogen atom or a hydroxy, alkoxy or acyloxy group; R3 | 08/26/1980 |
| 4218447 | Acyl derivatives of hellebrigenin There are prepared compounds corresponding to the general formula: ##STR1## in which R represents a 2,2-dimethylethenyl; isopropyl; nonyl; a C3 -C6 -cycloalkyl radical; a phenyl group substituted by at least one nitro group, or ... | 08/19/1980 |
| 4217280 | Amino-3-cardenolide derivatives, process for their preparation, and pharmaceutical compositions containing same Amino-3-cardenolide derivatives represented by the general formula (I) ##STR1## wherein n and m, which may be the same or different, each represents an integer from 0 to 4; R1, R2, R4, R5 and R6, whic... | 08/12/1980 |
| 4175078 | Cardenolide and bufadienolide derivatives of ajmaline and process for producing same According to the invention, the novel substances are the cardenolide and adienolide derivatives of ajmaline of the general formula ##STR1## wherein R is cardenolide or bufadienolide of the general formula ##STR2## Z is an unsaturated five-membe... | 11/20/1979 |
| 4115539 | Analytical or clinical derivatives, tagged derivatives and methods of analysis using such derivatives Novel isocyanates such as, for example, blocked L-tyrosine methyl ester isocyanate, are reacted with compounds of biological, clinical interest or the like such as, for example, digoxin, to form derivatives receptive to tagging, as by radiolabeling. The t... | 09/19/1978 |
| 4102884 | 14 ଲ-Hydroxy 3-deoxycardenolides Novel compounds of the formula ##STR1## useful as pharmaceutical compounds are disclosed. Processes are also disclosed for their preparation.... | 07/25/1978 |
| 4082747 | Chemical process An improved process for coupling an amino acid or derivative thereof to a cardiotonic glycoside derivative.... | 04/04/1978 |
| 4060607 | Cardenolide derivatives Cardiotonic cardenolide derivatives of the formula ##STR1## wherein n, m, R1 to R9 are as hereinafter defined, the mineral or organic salts thereof and a process for their preparation.... | 11/29/1977 |
| 4030886 | Saturation analysis The invention provides a method and a kit for the saturation analysis of a steroid characterized by the use of a selenium-75 labelled version of the steroid to be assayed. Selenium-75 derivatives of steroids are quite simple to prepare and have practical ... | 06/21/1977 |
| 4000125 | Novel cardiotonic steroids, process for their preparation and therapeutical use The invention relates to novel steroid compounds having the formula ##STR1## and their glycoside derivatives containing a pyridazine ring, in which particularly the substituent R4 is a hydroxy group or a hexopyranoside unit or a chain of t... | 12/28/1976 |
| 3981982 | Radioimmunoassay for determining the digoxin content of a sample A competitive radioimmunoassay for the measurement of digoxin in a serum sample in which the non-radioactive digoxin competes with a constant amount of a radioactively labeled digoxin tyramine analog comprising 3-O-(4-Hydroxyphenethylcarbamoyl) digoxigeni... | 09/21/1976 |
| 3954739 | Biological reagent Compounds of formula (VIII) wherein R1, r2, r3, r4 and R5 are each selected from hydrogen and an hydroxyl group and at least four are hydrogen; B is an alkylene chain of from 1 to 4 carbon atoms; R is selected ... | 05/04/1976 |