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| Number | Title | Issue Date |
| 7417140 | 7α-Hydroxyacetyl and 7α-Hydroperoxyacetyl-substituted steroid compounds The present invention involves intermediates, including a 7α-substituted steroid (II), and processes which are used to prepare eplerenone, a useful pharmaceutical agent. ... | 08/26/2008 |
| 7414127 | 7 α-Enedione-substituted steroid compounds The present invention involves intermediates, including a 7α-substituted steroid (II), and processes which are used to prepare eplerenone, a useful pharmaceutical agent. ... | 08/19/2008 |
| 7411062 | 7α-biscarbonyl-substituted steroid compounds The present invention involves intermediates, including a 7α-substituted steroid (II), and processes which are used to prepare eplerenone, a useful pharmaceutical agent. ... | 08/12/2008 |
| 7235655 | Processes to prepare eplerenone The present invention involves intermediates, including a 7α-substituted steroid (II), and processes which are used to prepare eplerenone, a useful pharmaceutical agent. ... | 06/26/2007 |
| 6262042 | 17ଲ-amino and hydroxylamino-11ଲ-arylsteroids and their derivatives having agonist or antagonist hormonal properties The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.... | 07/17/2001 |
| 5489582 | 14-deoxy-14-cardenolides 3ଲ-thioderivatives and pharmaceutical composition comprising same for treating cardiovascular disorders 14-Deoxy-14-cardenolides 3ଲ-thioderivatives and pharmaceutical compositions comprising same for treating cardiovascular disorders, such as heart failure and hypertension, are disclosed.... | 02/06/1996 |
| 5478817 | Digitoxigenin and dihydrodigitoxigenin 3ଲ-derivatives and pharmaceutical compositions comprising same for the treatment of cardiovascular disorders Digitoxigenin and dihydrodigitoxigenin 3ଲ-derivatives, a process for their preparation and pharmaceutical compositions containing same for the treatment of cardiovascular disorders such as heart failure and hypertension are disclosed.... | 12/26/1995 |
| 4550163 | Ligand analog-irreversible enzyme inhibitor conjugates The present invention encompasses a method for determining ligands in test samples comprising intermixing with the test sample a ligand analog-irreversible enzyme inhibitor conjugate and a binding protein bindable to the ligand and the ligand analog-irrev... | 10/29/1985 |
| 4495102 | Aminoalkyl steroids Compounds of Formula I and II are useful as potent antiarrythmic agents without significant effect on cardiac output and blood pressure.... | 01/22/1985 |
| 4380624 | Novel isomers of bufalin and resibufogenin and their preparation This invention relates to novel isomers of naturally occurring cardiotonic compounds, specifically novel isobufalins and novel isoresibufogenins. This invention also relates to a novel method of preparing the novel isomers.... | 04/19/1983 |
| 4331802 | Organometallic reagents and their use in the synthesis of cardenolides and isocardenolides A method for synthesizing a cardenolide or isocardenolide by subjecting an ,ଲ-unsaturated steroidal 17-ketone to a double bond shift and hydrogenation to produce a (C/D cisoid) ketone which is treated with an organometallic reagent to yield a... | 05/25/1982 |
| 4155906 | Process for preparing steroidal 3-oxo-4,6-dienes such as 17-hydroxy-3-oxo-17-pregna-4,6-diene-21-carboxylic acidγ-lactone A process for preparing 17-hydroxy-3-oxo-17-pregna-4,6-diene-21-carboxylic acid γ-lactone by contacting 17-hydroxy-3-oxy-17-pregna-3,5-diene-21-carboxylic acid γ-lactone with an appropriate halogenating agent in the presence of a... | 05/22/1979 |
| 4102884 | 14 ଲ-Hydroxy 3-deoxycardenolides Novel compounds of the formula ##STR1## useful as pharmaceutical compounds are disclosed. Processes are also disclosed for their preparation.... | 07/25/1978 |
| 4097477 | Steroid compounds and processes thereof Novel steroids of the formula ##STR1## Also there are provided processes for preparing such compounds. The new compounds are useful as intermediates in the preparation of known cardenolides; various of the compounds have other uses as blocking agents... | 06/27/1978 |
| 4082747 | Chemical process An improved process for coupling an amino acid or derivative thereof to a cardiotonic glycoside derivative.... | 04/04/1978 |
| 4062843 | 23-Hydroxy-3-oxo-24-norchola-4,17(20)-dien-21-oic acid γ-lactone and intermediates thereto 23-Hydroxy-3-oxo-24-norchola-4,17(20)-dien-21-oic acid γ-lactone, intermediates thereto, and antiviral utility thereof are disclosed.... | 12/13/1977 |
