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| Number | Title | Issue Date |
| 8163898 | 4-sulfonylpiperidine derivatives [PROBLEMS] To provide compounds useful as preventives or remedies for circulatory diseases, nervous diseases, metabolic diseases, reproductive system diseases, and digestive diseases. [MEANS FOR SOLVING PROBLEMS] Compounds represented by the gen... | 04/24/2012 |
| 8129519 | Derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine and uses thereof Chemical agents, such as disulfonamide derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulat... | 03/06/2012 |
| 8067582 | Fused heterocyclic compounds useful as modulators of nuclear hormone receptor function Disclosed are fused heterocyclic compounds of Formula (I) or pharmaceutically-acceptable salts or stereoisomers thereof. Also disclosed are methods of using such compounds in the treatment of at least one androgen receptor-associated condition, such as, for example,... | 11/29/2011 |
| 8049005 | Substituted tetrahydropyrazolo-pyrido-azepine compounds The present invention relates to substituted tetrahydropyrazolo-pyrido-azepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted tetrahydropyrazolo-pyrido-azepine compounds... | 11/01/2011 |
| 7879995 | Tetraphenylene compounds for organic electroluminescent device An organic electroluminescent device, which has, between a pair of electrodes, at least one organic layer including a light-emitting layer, in which the organic layer contains a specific tetraphenylene compound, and in which the light-emitting layer contains a phosp... | 02/01/2011 |
| 7408058 | Regioisomerically pure oxochlorins and methods of synthesis A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydronchlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. T... | 08/05/2008 |
| 7385053 | Functionalized compositions for improved immobilization The present invention relates to improved covalent coupling of two or more entities such as biomolecules, polymer compositions, organic/inorganic molecules/materials, and the like, including their combinations, through one or more novel reactive groups attached to l... | 06/10/2008 |
| 7345301 | Mixtures of matrix materials and organic semiconductors capable of emission, use of the same and electronic components containing said mixtures The present invention describes new types of material mixtures composed of at least two substances, one serving as a matrix material and the other being an emission material capable of emission, the latter comprising at least one element of atomic number greater tha... | 03/18/2008 |
| 7314929 | Organoselenium compounds for cancer chemoprevention A compound containing an alkylene selenocyanate or an alkylene isoselenocyanate moiety effective to prevent the occurrence or progression of cancer or a precancerous condition. The compound can be provided and administered in the form of a pharmaceutical composition... | 01/01/2008 |
| 7241883 | Functionalized compositions for improved immobilization The present invention relates to improved covalent coupling of two or more entities such as biomolecules, polymer compositions, organic/inorganic molecules/materials, and the like, including their combinations, through one or more novel reactive groups attached to l... | 07/10/2007 |
| 7160732 | Fluorescein-based metal sensors, and methods of making and using the same The present invention is directed, in part, to fluorescein-based ligands for detection of metal ions, and methods of making and using the same. ... | 01/09/2007 |
| 7129233 | Mandelic acid derivatives and their use as thrombin inhibitors There is provided a compound of formula I wherein Ra, R1, R2, Y and R3 have meanings given in the description and pharmaceutically-acceptable derivatives (including pro... | 10/31/2006 |
| 7078130 | Metallic mesoporous transition metal oxide molecular sieves, room temperature activation of dinitrogen and ammonia production This invention provides novel stable metallic mesoporous transition metal oxide molecular sieves and methods for their production. The sieves have high electrical conductivity and may be used as solid electrolyte devices, e.g., in fuel cells, as sorbents, e.g. for h... | 07/18/2006 |
| 7033564 | Lithium aluminum hydride-based selenating reagent and preparation methods using same A selenating reagent obtained by reacting lithium aluminum hydride with selenium powder in an organic solvent. In addition, a method for preparing a selenating reagent includes reacting lithium aluminum hydride with selenium powder in an organic solvent. Also, a met... | 04/25/2006 |
| 6894063 | Substituted urea neuropeptide Y Y5 Receptor antagonists A novel class of compounds such as antagonists of the neuropeptide Y Y5 receptor, methods of making such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compou... | 05/17/2005 |
| 6894039 | Selenophene anti-tumor agents Novel selenophene compounds useful as anti-tumor agents are described. Preferred compounds include compounds of formula I: wherein R1 and R2 are independently selected fro... | 05/17/2005 |
| 6803447 | Preparation of supramolecular polymers by copolymerization of monomers containing quadruple hydrogen bonding units with regular monomers The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more monomers of choice. The resulting polymers show unique new characteri... | 10/12/2004 |
| 6784193 | Mutilin derivatives and their use as antibacterials A compound of formula (I) wherein R2 is arylene or heterocyclene; or R and R2 together with the nitrogen atom to which they are attached form non-aromatic heterocyclene; and the other residues have various meanings, useful as pharmaceuticals, e... | 08/31/2004 |
| 6689174 | N-benzyl-p-phenylenediamine-derivatives containing coloring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives Dyes, containing N-benzyl-p-phenylenediamine derivatives of the general formula (I) or their physiologically compatible salts, ##STR1## for keratin fibers, and new N-benzyl-p-phenylenediamine derivatives.... | 02/10/2004 |
| 6676925 | Sigma-2 receptors as biomarkers of tumor cell proliferation Detectably-labeled compounds of formula (I) wherein A,B,C,D,E,F,R,X,Y and Z have any of the meanings given in the specification, and their pharmaceutically acceptable salts, are useful in competitive assays to assay for the presence of 2 receptors. Also d... | 01/13/2004 |
| 6620804 | Selenophene anti-tumor agents Novel selenophene compounds useful as anti-tumor agents are described. Preferred compounds include compounds of formula I: ##STR1## wherein R1 and R2 are independently selected from the group consisting of; ##STR2## H, CHO, ... | 09/16/2003 |
| 6576730 | Organic initiators and their use in the polymerization of unsaturated monomers Process for the polymerization of unsaturated vinyl and/or vinylidene monomers which comprises reacting one or more monomers in the presence of heterocyclic initiators having a nitrogen atom bound to an oxygen atom at a temperature ranging from 100 to 130... | 06/10/2003 |
| 6514298 | Fuel additive and fuel composition Fuel additives comprise a compound having a group represented by the formula >C.dbd.=N-- (1). Also disclosed are fuel compositions containing such additives. The additives have a superior detergent effect to conventional gasoline detergents and an excell... | 02/04/2003 |
| 6506567 | Water-soluble flourescent intercalator compound A water-soluble fluorescent intercalator compound having the formula: F--La--X F is a fluorescent moiety, X is a divalent cyclic group, and La is a linking group, and at least one of X and La has a site imparting water solubility to the compound or a site that... | 01/14/2003 |
| 6469065 | Nitrosated and nitrosylated -adrenergic receptor antagonist, compositions and methods of use The present invention describes novel nitrosated and/or nitrosylated -adrenergic receptor antagonists, and novel compositions containing at least one nitrosated and/or nitrosylated -adrenergic receptor antagonist, and, optionally, one or mor... | 10/22/2002 |
| 6458827 | Method of locking 1-OH of vitamin D compounds in axial orientation A method of modifying or altering the structure of a 1-hydroxylated vitamin D compound to increase its biological activity by altering the conformational equilibrium of the A-ring to favor a chair conformation that presents the 1-hydroxyl in... | 10/01/2002 |
| 6455573 | Glycosidase inhibitors and methods of synthesizing same A method for synthesizing Salacinol, its stereoisomers, and non-naturally occurring selenium and nitrogen analogues thereof having the general formula (I): ##STR1## The compounds are potentially useful as glycosidase inhibitors. The synthetic schemes... | 09/24/2002 |
| 6383230 | Cationic monobenzenic dyes, their use for the oxidation-dyeing of keratin fibers, dye compositions and dyeing processes The invention relates to novel monobenzenic dyes including at least one cationic group Z, Z chosen from quaternized aliphatic chains, aliphatic chains including at least one quaternized saturated ring and aliphatic chains including at least one quaternize... | 05/07/2002 |
| 6375930 | Membrane incorporation of texaphyrins Compositions having a texaphyrin-lipophilic molecule conjugate loaded into a biological vesicle and methods for imaging, diagnosis and treatment using the loaded vesicle are provided. For example, liposomes or red blood cells loaded with a paramagnetic te... | 04/23/2002 |
| 6355631 | Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and their preparation The present invention relates to pharmaceutical compositions containing, as an active ingredient, at least one compound of formula: ##STR1## in which R1 represents a radical --N(R4)R5, --N(R4)--CO--R5... | 03/12/2002 |
| 6337394 | Compounds There is provided compounds of formula I, ##STR1## wherein R1, R2, R3, Rx, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin... | 01/08/2002 |
| 6274738 | Carboxamide derivatives having aryl and thiazole rings The invention provides DNA primase assays suitable for identifying DN primase modulating agents, methods of modulating DNA primase activity, compounds for modulating DNA primase activity, and compositions which modulate DNA primase.... | 08/14/2001 |
| 6258775 | Bi-aromatic compounds, pharmaceutical and cosmetic compositions containing same and uses The invention relates to novel biaromatic compounds having general formula I ##STR1## and their use in pharmaceutical compositions for use in human and veterinary medicine, in particular for treating dermatological, rheumatic, respiratory, cardiovasc... | 07/10/2001 |
| 6242561 | Substituted polythiophenes, processes for their preparation their use Novel polythiophene-containing structural units of the general formulae (I) and (II) ##STR1## processes for their preparation, monomers for their preparation, their use in various industrial fields, and an electrically conductive material comprising ... | 06/05/2001 |
| 6197922 | Polyselenophenes, the preparation thereof and the use thereof Novel polyselenophenes comprising one or more structural units of the formulae (I) or (II) or (I) and (II) ##STR1## processes for preparing them, monomers for their preparation, their use in various technical sectors, and an electrically conducting materi... | 03/06/2001 |
| 6187928 | Imidazolium cations and uses therefor Novel imidazolium compounds of the formula ##STR1## wherein A represents the atomic group necessary to form a heteroaromatic ring, which may be optionally substituted by one or more R substituents selected from the group consisting of aryl, heteroaryl, lo... | 02/13/2001 |
| 6166003 | Heterocyclic compounds for cancer chemoprevention A compound comprising a heterocyclic moiety, such as a thiophene, covalently attached to an alkylene isothiocyanate moiety. The compound is effective to prevent the occurrence or progression of cancer or a precancerous condition, and can be used for thera... | 12/26/2000 |
| 6132475 | Diaminobenzene derivative compounds and dye compositions containing same New p-diaminobenzene derivative compounds of the formula (I): ##STR1## and physiologically compatible water soluble salts thereof are described, wherein X represents oxygen, sulfur, selenium or N-R9. Compositions for dyeing keratin fibers including a... | 10/17/2000 |
| 6121300 | Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts The present invention relates to compositions and methods for reversing advanced glycosylation end product-mediated cross-linking and protein aging. Accordingly, compositions are described which comprise thiazolium compounds substituted with heterocyclic ... | 09/19/2000 |
| 6107345 | Benzocyclobutane compounds A compound of formula (I): ##STR1## wherein: Z1, Z2, Z3, Z4, which may be identical or different, represent a group as defined in the description, X represents oxygen, S(O)p, --(CH2)n | 08/22/2000 |
