Celebrity Inventors
Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| RE43389 | Vessel for blood sampling The present invention relates to a vessel for withdrawing blood, the vessel containing a solution which comprises a guanidinium salt, a buffer substance, a reducing agent, and/or a detergent as components. The vessel is particularly suited for withdrawing blood whic... | 05/15/2012 |
| 8148071 | Methods and compositions for isolating nucleic acid The present invention relates to compositions and methods for isolating and purifying nucleic acid. In particular, the present invention relates to methods of isolating nucleic acid from cells for use in further analysis. ... | 04/03/2012 |
| 8101744 | Isolation and purification of nucleic acids with a solid phase Disclosed are water-soluble ionic liquids suitable for promoting adsorption of nucleic acids to a solid phase. The use thereof, particularly methods for the isolation of nucleic acids from an aqueous solution, as well as kits for performing those methods are disclos... | 01/24/2012 |
| 8097717 | Compositions comprising polidocanol and derivatives This invention relates to a composition comprising a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof. The invention is further related to uses of this composition and to a kit comprising the composition according to t... | 01/17/2012 |
| 8093373 | Plasmid purification The present invention relates to a method of isolating at least one plasmid from other components of a liquid, which method comprises the steps of providing a separation matrix comprised of one or more porous carriers, which carrier(s) present anion exchange groups ... | 01/10/2012 |
| 8067579 | Nucleic acid extraction method The present invention relates to a method for isolating nucleic acids from a nucleic acid containing sample, and a kit for carrying out said method. More specifically, it relates to a novel method for extracting nucleic acids from a nucleic acid containing sample, u... | 11/29/2011 |
| 8067580 | Isolation of DNA, RNA and protein from a single sample The invention provides a method for the separation and purification of two or three cellular components selected from genomic DNA, RNA and proteins from a single biological sample. The method comprises generating an aqueous solution containing the cellular component... | 11/29/2011 |
| 8034924 | Process for production of crystal of purine nucleoside compound Crystals of a purine nucleoside compound, particularly crystals of 2′,3′-dideoxyinosine, which have excellent storage stability and have a concentration of phosphate attached to the crystal of 25 ppm or more, may be produce by: (1) preparing an aqueous solution ... | 10/11/2011 |
| 8008475 | Method for isolating and purifying nucleic acids on surfaces The present invention involves a process for the isolation of nucleic acids on surfaces by means of at least the following steps: charging of a surface from a given direction with nucleic acids; immobilization of the nucleic acids on the surface; release of the immo... | 08/30/2011 |
| 7989615 | Separation of different isoforms of plasmid DNA using ultrafiltration The invention is a method for isolating a desired plasmid DNA isoform, typically a supercoiled isoform, which includes the steps of obtaining a quantity of bioreactor produced plasmid DNA in liquid form for purification, and passing the plasmid DNA through an ultraf... | 08/02/2011 |
| 7989614 | Isolation of nucleic acid The present invention provides a method of isolating nucleic acid from a sample, said method comprising contacting said sample with a detergent and a solid support, whereby soluble nucleic acid in said sample is bound to the support, and separating said support with... | 08/02/2011 |
| 7960542 | Process for purifying oligonucleotide synthons A process for the purification of an oligonucleotide synthon is provided. The process comprises subjecting an organic solution comprising an oligonucleotide synthon and lower molecular weight impurities to nanofiltration whereby the ratio of an oligonucleotide synth... | 06/14/2011 |
| 7923551 | Method of purifying RNA using kosmotropic salt The present invention provides a method of purifying RNA, including contacting a solid support with an acidic solution having a RNA-containing sample and a kosmotropic salt having a concentration of less than 1M, thereby binding the RNA to the solid support. Accordi... | 04/12/2011 |
| 7893250 | Demethylated and/or oxidized membrane DNA A process for the preparation of oxidized and/or demethylated antigens comprising the steps of treating a cell with a stress factor selected from the group consisting of UV-radiation, oxidizing reagents, heavy metal salts, drugs, n... | 02/22/2011 |
| 7893251 | Methods for selective isolation of nucleic acids from microbial cells present in samples containing higher eukaryotic cells and/or tissues The invention relates to the use of nucleases, especially DNA-degrading nucleases, for degrading nucleic acids in the presence of one or several chaotropic agents and/or one or several surfactants. The invention further relates to a method for purifying RNA from mix... | 02/22/2011 |
| 7884201 | Method for separating and purifying RNA A method for separating and purifying RNA including the steps of passing a sample solution containing a nucleic acid, a washing solution and a recovering solution through a nucleic acid-adsorbing porous membrane to adsorb nucleic, adsorbing, washing and recovering, ... | 02/08/2011 |
| 7807822 | Methods for purifying nucleic acids Methods are provided for producing highly purified compositions of nucleic acids by using a highly streamlined and readily automated process. The methods use static mixers for lysing cells and precipitating debris, followed by centrifugation and ion exchange chromat... | 10/05/2010 |
| 7803934 | Parallel preparation of high fidelity probes in an array format The present invention provides massively parallel oligonucleotide synthesis and purification for applications that utilize large collections of defined high-fidelity oligonucleotides (e.g., from about 101 to about 105 different sequences, gener... | 09/28/2010 |
| 7786295 | Method to isolate DNA An improved method for isolating DNA from biological samples is provided. ... | 08/31/2010 |
| 7767804 | Compositions and methods for using a solid support to purify RNA Reagents, methods and kits for the purification of RNA from biological materials are provided. ... | 08/03/2010 |
| 7754873 | Isolation of nucleic acid using colored buffers The present invention describes isolation of plasmid DNA from bacteria. The addition of dyes to the alkaline lysis based purification buffers (P1, P2, and P3) allows for improved visual monitoring of the steps of preparing a bacterial lysate fil... | 07/13/2010 |
| 7737268 | Method of recovering nucleic acids and kit for recovering nucleic acids Disclosure is a method of separately recovering deoxyribonucleic acid and ribonucleic acid from a biological sample solution. They are separated and recovered from a single biological sample by controlling pH values, temperature, and/or concentration of cationic ion... | 06/15/2010 |
| 7700762 | Plasmid DNA clarification A clarification system and method of using for plasmid DNA that is centrifugation-free. The system is comprised of a coarse filter, about 50 to about 200 microns pore size, followed by a prefilter of about 1 to about 2 micron pore size and then a final filter of abo... | 04/20/2010 |
| 7659392 | Method of separation using aromatic thioether ligands The present invention is a method of separating nucleic acid molecules from contaminants, such as proteins, in a solution and isolating one or more desired nucleic acid molecules, which method comprises the following steps (a) providing an aqueous adsorption solutio... | 02/09/2010 |
| 7655792 | Nucleic acid purification method The invention provides an improved method for the purification of nucleic acid molecules, which method comprises generating a cellular lysate containing the nucleic acid; contacting the lysate with an anion exchanger bound to a solid support matrix under conditions ... | 02/02/2010 |
| 7655793 | Nucleic acid purification method Disclosed is a process for separating and/or purifying a nucleic acid by elution of the nucleic acid from anion exchange resins under conditions of high salt concentration and the presence in the eluant of an additive comprising guanidine, or a guanidine-like deriva... | 02/02/2010 |
| 7655794 | Nucleic acid purification method The invention provides an improved method for the purification of nucleic acid molecules, which method comprises generating a cellular lysate containing the nucleic acid; contacting the lysate with an anion exchanger bound to a solid support matrix under conditions ... | 02/02/2010 |
| 7655791 | DNA amplification and sequencing using DNA molecules generated by random fragmentation The present invention is directed to methods to prepare a DNA molecule or a plurality of DNA molecules by random fragmentation. In some embodiments, the present invention regards preparing a template for DNA sequencing by random fragmentation. In specific embodiment... | 02/02/2010 |
| 7598371 | Nucleic acid separation using immobilized metal affinity chromatography An immobilized metal affinity chromatography (IMAC) method for separating and/or purifying compounds containing a non-shielded purine or pyrimidine moiety or group such as nucleic acid, presumably through interaction with the abundant aromatic nitrogen atoms in the ... | 10/06/2009 |
| 7589192 | pH dependent ion exchange material capable of selectively binding to nucleic acids in comparison with proteins, solid substrate having the material immobilized on its surface, and method of isolating a nucleic acid using the material or the solid substrate Provided is a pH dependent ion exchange material. The pH dependent ion exchange material has at least one monomer selected from the group consisting of M0, M1, M2 and M3 represented by the following formulae, provided that at least one monomer having A and at least ... | 09/15/2009 |
| 7550583 | Method of isolating, labeling and profiling small RNAs Disclosed herein is a method of selectively labeling non-messenger RNA molecules by isolating total RNA from a tissue or cell, dissolving the isolated RNA, blocking the 3′ end of the RNA and adding T4 RNA ligase and a labeled nucleic acid adaptor. With the results... | 06/23/2009 |
| 7435811 | Method for preferentially removing protein over nucleic acids using physical as well as chemical means of removal of the protein Provided is a method of removing protein while not removing nucleic acids from a biological sample containing protein, the method including: adding a compound of formula I below and a protein nucleating agent to the biological sample containing protein: | 10/14/2008 |
| 7424368 | Methods for identifying DNA copy number changes Methods of estimating genomic DNA copy number are disclosed. Amplified genomic DNA is hybridized to an array of allele specific SNP probes to generate a hybridization pattern. A value, S, is calculated for individual SNPs in the experimental sample, where S is the l... | 09/09/2008 |
| 7371830 | Method for separating biological material from a fluid using magnetic particles Magnetic particles are prepared containing a magnetic core coated with a glass layer having a substantially pore-free glass surface or having pores with a diameter of less than 10 nm. The particles are used for separating biological material such as nucleic acids. A... | 05/13/2008 |
| 7371531 | Use of an extraction control in a method of extracting nucleic acids The present invention relates to a method of ensuring the effectiveness of the extraction workup from a biological sample of nucleic acid. The inventive method is able to distinguish between possible defects in the extraction of nucleic acid from a sample and possib... | 05/13/2008 |
| 7371579 | Nickel-based reagents for detecting DNA and DNA-protein contacts The invention relates to a compound comprising a labeled nickel complex (FIG. 1) that is used to detect and purify nucleic acid sequences by forming an adduct between a specific nucleic acid base and the labeled nickel complex. The adduct can also be purified... | 05/13/2008 |
| 7368547 | Use of novel virulence-specific genes as targets for diagnosis and potential control of virulent strains of A method for identifying virulent strains of L. monocytogenes that includes the use of primers or probes in a PCR assay or hybridization technique that employs primers or probes, which are specific for virulence-specific genes of L. monocytogenes. Also... | 05/06/2008 |
| 7368561 | Isolation of antisense oligonucleotides The present invention relates to a method of isolating fully thioated single stranded antisense oligonucleotides from a biological solution, which method comprises the steps of contacting the biological solution with an immobilised metal ion adsorption chromatograph... | 05/06/2008 |
| 7361260 | Methods, articles and kits for labeling polymer gels The invention provides methods, apparatus and kits for integrally labeling polymeric gels, such as polyacrylamide and agarose gels, with indicia that can serve, inter alia, unambiguously to identify the individual gel, using polymeric film labeled with detectable in... | 04/22/2008 |
| 7355038 | Phase isolation process for biomacromolecule components The present invention relates to a phase isolation process for biomacromolecule components, after pretreating the substance to be isolated: 1) adding sufficient amount of buffer (one of the compound selected from ammonium sulfate, cesium chloride, sodium sulfate, an... | 04/08/2008 |
