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Class 536/24.32 - Probes for detection of microbial nucleotide sequences


Subclass of Class 536 - Organic compounds -- part of the class 532-570 series
Definition: Fragments of nucleic acid which are single strands of DNA
No. of patents: 1769
Last issue date: 05/29/2012


1                      
NumberTitleIssue Date
8188256Primer and probe for detection of
The present invention discloses an oligonucleotide which comprises a part or the entire sequence of the nucleotide sequence shown in SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 or SEQ ID NO: 8, or a part or the en...
05/29/2012
8119788Compositions and methods for the detection of species
Compositions and methods for detecting and/or differentiating among Candida organisms, including C. albicans and C. dubliniensis, are disclosed. Exemplary methods involve screening a sample suspected of containing at least one or more Candida...
02/21/2012
8114598High-sensitivity assays for pathogen detection using metal enhanced fluorescence
The present invention relates to an assay including a surface having silver colloids or islands attached thereto. Attached to the surface and/or silver colloids/islands are polynucleotides which are complimentary to a target polynucleotide sequence. The assay is per...
02/14/2012
8106178Probe, probe set, probe-immobilized carrier, and genetic testing method
A nucleic acid probe for classification of pathogenic bacterial species is capable of collectively detecting bacterial strains of the same species and differentially detecting them from other bacterial species. Any one of the base sequences of SEQ ID NOS. 81 to 83 a...
01/31/2012
8071751Human parvovirus: bocavirus
Provided herein are sequences of the genomes and encoded proteins of a new human parvovirus, Bocavirus-2, and variants thereof. Also provided are methods of detecting the Bocavirus-2 and diagnosing Bocavirus-2 infection, methods of treating or preventing Bocavirus-2...
12/06/2011
8058423High-risk human papillomavirus detection
This invention provides compositions and methods for detecting HPV in a sample. This invention also provides related kits, systems, and computers. ...
11/15/2011
8049001Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
11/01/2011
8039607Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
10/18/2011
8034918Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
10/11/2011
8034919Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
10/11/2011
8021846Method for determining azole resistance in
There is disclosed a method for determining azole resistance in Candida glabrata. A biological sample containing Candida glabrata is obtained and a normalized mRNA level of CDR1 gene is determined using qRT-PCR. Using a microbroth dilution assay conduc...
09/20/2011
7960539Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
06/14/2011
7960538Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
06/14/2011
7951932Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
05/31/2011
7935809Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
05/03/2011
7935810Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
05/03/2011
7829691Detection of nucleic acids by type specific hybrid capture method
Target-specific hybrid capture (TSHC) provides a nucleic acid detection method that is not only rapid and sensitive, but is also highly specific and capable of discriminating highly homologous nucleic acid target sequences. The method produces DNA-RNA hybrids which ...
11/09/2010
7795418Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishing...
09/14/2010
7786289Method and kit for identifying antibiotic-resistant microorganisms
The invention provides a rapid sample-processing method for preparing hybridization reaction mixtures substantially depleted of RNA, and a method of identifying the methicillin-resistance status and vancomycin-resistance status of an organism. ...
08/31/2010
7728123Internal control nucleic acid molecule for nucleic acid amplification systems
The invention provides an internal control nucleic acid molecule including at least one forward primer binding site, at least one reverse primer binding site, and at least one amplifiable region, wherein the forward primer binding site, the reverse primer binding si...
06/01/2010
7601831Methods, kits and assay system for detecting drug-resistant
The present invention relates to methods, kits and assay system for detecting drug-resistant Mycobacterium tuberculosis of suspected patient. The system of the present invention largely reduces the whole process of drug-resistant M. tuberculosis detect...
10/13/2009
7579454Method for detecting gram-positive bacteria
The present invention relates to a method for detecting and/or identifying Gram-positive bacteria with high GC content, in particular mycobacteria. The method comprises a nucleic acid amplification reaction and a subsequent hybridization reaction with suitable prime...
08/25/2009
7553956Polynucleotide probe and primer for detecting beer-clouding lactic acid bacteria and method of detecting beer-clouding lactic acid bacteria
An object of the present invention is to provide probes and primers for detecting beer-spoilage lactic acid bacteria with accuracy. The probes and primers for detecting beer-spoilage lactic acid bacteria according to the present invention each comprises a nucleotide...
06/30/2009
7553957Methods and kits for detecting classical swine fever virus
The present invention provides methods and kits for detecting CSFV. The present invention also provides oligonucleotides for detecting CSFV. ...
06/30/2009
7534877Non-M, non-O HIV-1 strains, fragments and uses
Retroviral strains of the non-M, non-O HIV-1 group, in particular a strain designated YBE30, its fragments and also its uses as a diagnostic reagent and as an immunogenic agent. The HIV-1 viruses which differ both from the M group and the O group exhibit the ...
05/19/2009
7504493Characterization of the yeast transcriptome
Yeast genes which are differentially expressed during the cell cycle are described. They can be used to study, affect, and monitor the cell cycle of a eukaryotic cell. They can be used to obtain human homologs involved in cell cycle regulation. They can be used to i...
03/17/2009
7504494Multiplex PCR assay
This invention relates to a multiplex PCR assay capable of screening or detecting the relevant microbial organism specific to Mycobacterium tuberculosis, Toxoplasma gondii, pathogenically important fungii and cytomegalo virus (CMV) in a sample, comprising a r...
03/17/2009
7442523Nucleic acid and amino acid sequences relating to for diagnostics and therapeutics
The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polype...
10/28/2008
7439020Genomic markers of hepatitis B virus associated with hepatocellular carcinoma
The present invention provides methods of predicting a pre-disposition of HBV-infected individuals to develop hepatacellular carcinoma (HCC). ...
10/21/2008
7439016Detection of nucleic acids by type-specific hybrid capture method
Target-specific hybrid capture (TSHC) provides a nucleic acid detection method that is not only rapid and sensitive, but is also highly specific and capable of discriminating highly homologous nucleic acid target sequences. The method produces DNA-RNA hybrids which ...
10/21/2008
7439022Nucleic acids for detection of
Isolated nucleic acids and methods for detecting nucleic acid of Listeria in a test sample are provided. The isolated nucleic acids may be incorporated into polymerase chain reactions to provide for the rapid detection of Listeria in samples. ...
10/21/2008
7432366BASB034 polypeptides and used thereof
Provided are Moraxella catarrhalis BASB034 polypeptides and immunogenic fragments of BASB034 polypeptides. Preferably, the immunogenic fragments have at least 15 amino acids that match an aligned contiguous segment of SEQ ID NOs:2, 4, 6 or 8. The immunogenic ...
10/07/2008
7429654Cold-shock regulatory elements, constructs thereof, and method of use
Regulatory elements of the 5′UTR of cold-shock inducible genes that prolong the expression of cold-shock inducible genes under conditions that elicit the cold-shock response in a bacterium, repress the expression of the cold-shock inducible genes under physiologic...
09/30/2008
7429454DNA probes useful in detecting δ-endotoxin-encoding sequences and uses thereof
Disclosed are novel DNA probes useful in detecting a nucleic acid sequence encoding a novel Lepidopteran- and Coleopteran-active δ-endotoxin polypeptide. Also disclosed are nucleic acid detection methods and kits involving the novel DNA probes. ...
09/30/2008
7427483Utilization of nucleotide probes in ELISA procedure for the quantitative determination of DNA in malaria
The present invention is the development of a simple and specific quantitative method for the determination of P. falciparum DNA in malaria that involves the direct detection of the highly 42-kDa conserved C-terminal region of P. falciparum merozoite s...
09/23/2008
7427472Methods for the differentiation and identification of medically important endemic fungi
Methods of detecting a dimorphic fungus, including differentiating a dimorphic fungus from other fungi are disclosed. A sample suspected of containing a nucleic acid of a fungus, such as an internal transcribed spacer-2 (ITS2) nucleic acid sequence of a dimorphic fu...
09/23/2008
7419672Genes and proteins, and their use
According to the present invention, a series of genes are identified in Group B Streptococcus, the products of which may be associated with the outer surface of the organism. The genes, or functional fragments thereof, may be useful in the preparation of therapeutic...
09/02/2008
7416863Nucleotide sequences for encoding of the lysR2-gene
Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No...
08/26/2008
7417138PNA chip for determining genotypes of mycobacterial species using plastic substrate coated with epoxy group-containing polymer and method of determining genotypes of mycobacterial species using the PNA chip
Provided are a PNA chip for determining the genotypes of mycobacterial species in which probe PNAs having DNA sequences of SEQ ID NOs: 5-28 are immobilized on a plastic substrate coated with an epoxy group-containing polymer, and a method of determining the genotype...
08/26/2008
7413708Methods and reagents for combined PCR amplification
An oligonucleotide probe is disclosed, the probe including an oligonucleotide, a fluorescer molecule attached to a first end of the oligonucleotide and a quencher molecule attached to the opposite end of the oligonucleotide. The probe is rendered impervious to diges...
08/19/2008
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