Class 536/23.5 - Encodes an animal polypeptide

Subclass of Class 536 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which are DNA fragments which encode specific
No. of patents: 6997
Last issue date: 05/29/2012

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Number	Title	Issue Date
8188046	Amyloid beta peptides and methods of use The application describes several mutant amyloid beta peptides and specific regions which are useful in the therapeutic and diagnostic of neurological diseases. The application further describes methods of using these mutant peptides as treatment and reagents for di...	05/29/2012
8173793	Nucleic acids encoding modulators of body weight The present invention relates generally to the control of body weight of animals including mammals and humans, and more particularly to nucleic acids encoding materials identified herein as modulators of weight. In its broadest aspect, the present invention relates ...	05/08/2012
8158351	Method for determining inflammatory disease It is an object of the present invention to provide a method for determining inflammatory diseases including myocardial infarction as a typical example, which involves identifying polymorphisms associated with myocardial infarction and using the gene polymorphisms, ...	04/17/2012
8158769	Members of the capsaicin/vanilloid receptor family of proteins and uses thereof The invention provides isolated nucleic acids molecules, designated hVR-1, hVR-2, and rVR-2 nucleic acid molecules, which encode novel members of the Capsaicin/Vanilloid receptor family. The invention also provides antisense nucleic acid molecules, recombinant expre...	04/17/2012
8153774	Human T1R2 taste receptor nucleic acids and cells containing these nucleic acids Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in taste signaling, and the genes and cDNA encoding the same, are described...	04/10/2012
8148507	Nucleic acid encoding TNFx protein Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.	04/03/2012
8148074	IRF-5 haplotypes in systemic lupus erythematosus Methods and materials involved in diagnosing SLE are provided herein. The methods and materials can be used to diagnose SLE and/or assess a mammal's susceptibility to develop SLE, based on the presence or absence of one or more IRF-5 variants. ...	04/03/2012
8143384	Mutation of PRPS1 gene causing CMTX5 disease and the use thereof Disclosed is a gene mutation associated with peripheral neuropathy associated with sensorineural hearing loss and optic neuropathy. More specifically, disclosed are: a polynucleotide comprising a mutation associated with peripheral neuropathy associated with sensori...	03/27/2012
8138323	Isolated cDNA encoding tumor necrosis factor binding protein II, its purification, and vectors, hosts and processes using such cDNA An isolated DNA molecule has the sequence of encoding a fragment of encoding Tumor Necrosis Factor (TNF) Binding Protein II. It has a length sufficient to serve as an immunogen for raising antibodies against a polypeptide that is a fragment of TNF Binding Protein II...	03/20/2012
8124749	Targeted cell death The present invention provides compositions and methods for studying neuropathy. The compositions and methods provided herein are particularly useful for screening agents of therapeutic and/or diagnostic potential. ...	02/28/2012
8119785	Nucleic acid sequences and homologous recombination vectors for distruption of a Fel D I gene A transgenic cat with a phenotype characterized by the substantial absence of the major cat allergen, Fel d I. The phenotype is conferred in the transgenic cat by disrupting the coding sequence of the target gene with a specialized construct. The phenotype of the tr...	02/21/2012
8119786	Nucleic acids encoding CCL27 Novel CC chemokines from human, reagents related thereto including purified proteins, specific antibodies and nucleic acids encoding these chemokines are provided. Also provided are methods of making and using said reagents and diagnostic kits. ...	02/21/2012
8114975	Protein tyrosine kinase substrate LAT and its use in the identification of (ANT) agonists of the kinase The invention generally relates to compositions and methods for identifying and testing tyrosine kinase signaling pathway agonists and antagonists, and more particularly, methods and compositions for screening compounds and identifying compounds that will modulate t...	02/14/2012
8088907	Detection of mutations in a gene associated with resistance to viral infection, OAS1 A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded ...	01/03/2012
8071745	Polynucleotides encoding rod-derived cone viability factor (rdcvf) and methods of using the same Disclosed are methods and compositions for early diagnosis, monitoring and treatment of retinal dystrophy, age-related macular degeneration, Bardet-Biedel syndrome, Bassen-kornzweig syndrome, best disease, choroidema, gyrate atrophy, congenital amourosis, refsun syn...	12/06/2011
8071746	Isolated nucleic acid molecule encoding a peptide or peptide analog comprising the SEQ ID No. 3 Disclosed herein are peptides or peptide analogs with multiple amphipathic α-helical domains that promote lipid efflux from cells via an ABCA1-dependent pathway. Also provided herein are methods of using multi-domain amphipathic α-helical peptides or peptide analo...	12/06/2011
8067563	Tumor suppressor gene, p471NG3 The invention provides isolated nucleic acid and amino acid sequences of novel human tumor suppressors, antibodies to such tumor suppressors, methods of detecting such nucleic acids and proteins, methods of screening for modulators of tumor suppressors, and methods ...	11/29/2011
8067562	Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1 The present invention provides novel activin IIB5 receptor polypeptides capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the receptor...	11/29/2011
8053189	Method for the diagnosis of colorectal cancer The object of the present invention refers to an in vitro method for diagnosing colorectal cancer based on the determination from a biological sample obtained from a subject, of promoter methylation status of at least one of the genes APC, RARB2 and p14 and, optiona...	11/08/2011
8048999	Nuclear reprogramming factor There is provided a nuclear reprogramming factor for a somatic cell, which comprises a gene product of each of the following three kinds of genes: an Oct family gene, a Klf family gene, and a Myc family gene, as a means for inducing reprogramming of a differentiated...	11/01/2011
8030468	Human T2R51 taste receptor nucleic acid sequences and polypeptides Newly identified mammalian taste-cell-specific G Protein-Coupled Receptors and the genes encoding said receptors are described. Specifically, T2R taste G Protein-Coupled Receptors that are believed to be involved in bitter taste sensation, and the genes encoding the...	10/04/2011
8026353	Nucleic acid molecules encoding human 4-1BB The human receptor H4-1BB has been isolated, sequenced and disclosed herein. The cDNA of the human receptor H4-1BB is about 65% homologous to the mouse cDNA 4-1BB and was isolated by using probes derived from cDNA 4-1BB. A fusion protein for detecting cell membrane ...	09/27/2011
8017751	hT2R54 receptor polypeptides and nucleic acid sequences Functional assays that detect the effect of a particular compound or compounds on the activation of at least one human T2R polypeptide are provided. These assays include e.g., assays which detect the effect of said compound on intracellular calcium, second messenger...	09/13/2011
8017752	Soluble epidermal growth factor receptor isoforms The present invention relates to the discovery of soluble isoforms of an Epidermal Growth Factor Receptor, or sErbB1 variants, the provision of the sequences of nucleic acids encoding these isoforms, purified recombinant proteins, novel antibodies specific for these...	09/13/2011
8008464	SSX-4 peptides presented by HLA class II molecules The invention describes HLA class II binding peptides encoded by the SSX-4 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4+ T lymphocytes....	08/30/2011
8008463	Compositions and methods for diagnostics and therapeutics for hydrocephalus The present disclosure relates to RFX4_v3 protein and nucleic acids encoding the RFX4_v3 protein. The present disclosure provides non-human transgenic animals with altered RFX4_v3 genes, and provides assays for the detection of RFX4_v3 and RFX4_v3 polymorphisms asso...	08/30/2011
7994301	Modulators of body weight, corresponding nucleic acids and proteins Modulators of weight, including, for example, two isoforms of murine and human ob polypeptides, are provided, as well as diagnostic and therapeutic uses and methods comprising such. Also provided are nucleotide sequences, degenerate variations thereof, and proteins ...	08/09/2011
7982023	Bag proteins and nucleic acid molecules encoding them The present invention provides a family of BAG-1 related proteins from humans (BAG-1L, BAG-1, BAG-2, BAG-3, BAG-4 and BAG-5), the invertebrate C. elegans (BAG-1, BAG-2) and the fission yeast S. pombe (BAG-1A, BAG-1B) and the nucleic acid molecules that...	07/19/2011
7977470	Human Ron-related gene variant associated with cancers The invention relates to the nucleic acid and polypeptide sequences of three novel human Ron-related gene variants (Ron-V1, Ron-V2, and Ron-V3). The invention also provides a process for producing the polypeptides of the variants, as well as uses for the nucleic aci...	07/12/2011
7973151	Nucleic acid encoding modified human thymic stromal lymphopoietin Modified, furin resistant human TSLP polypeptides and polynucleotides encoding the modified human TSLP polypeptides are provided. Pharmaceutical compositions, B and T cell activation agents, assays and methods of use are also described. ...	07/05/2011
7968693	Human T2R51 nucleic acid sequences and polypeptides Newly identified mammalian taste-cell-specific G Protein-Coupled Receptors and the genes encoding said receptors are described. Specifically, T2R taste G Protein-Coupled Receptors that are believed to be involved in bitter taste sensation, and the genes encoding the...	06/28/2011
7964713	Nucleic acid molecules encoding thymic stromal lympopoietin receptor proteins and a process for producing the encoded polypeptides thereof The present invention provides Thymic Stromal Lymphopoietin Receptor (TSLPR) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing TSLPR polypeptides. The inven...	06/21/2011
7960531	EG-VEGF nucleic acids and polypeptides and methods of use The present invention is directed to novel polypeptides designated herein as EG-VEGF and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules co...	06/14/2011
7960530	Fluorescent protein An object of the present invention is to provide a novel fluorescent protein derived from favia favus. The present invention provides a fluorescent protein derived from favia favus having the following properties: (1)...	06/14/2011
7956172	Fluorescent protein and chromoprotein It is an object of the present invention to provide a novel fluorescent protein and a novel chromoprotein. The present invention provides a novel fluorescent protein derived from Montipora sp., Acropora sp. and Lobophytum crassum, and a novel ch...	06/07/2011
7951931	Nucleic acid encoding sodium channel SCN3A alpha subunits The present invention relates to epilepsy. More particularly, the present invention relates to idiopathic generalized epilepsy (IGE) and to the identification of three genes mapping to chromosome 2, which show mutations in patients with epilepsy. The invention furth...	05/31/2011
7951930	Cultured cell lines expressing mutant gene Using protein visualization techniques, cell lines stably expressing GFP-fused full-length and mutant APCs were obtained from cultured Xenopus laevis renal epithelial A6 cells. The use of these cells showed that mutant APCs, whose C-terminal region is absent,...	05/31/2011
7951928	Gene encoding a protein and preventive/remedy for neurodegenerative diseases such as polyglutamine diseases by utilizing the same To provide a novel protein that can be a preventive/remedy in neurodegenerative diseases such as polyglutamine diseases based on the finding obtained by revealing the relationship between transcriptional dysfunction and neuronal death. Disclosed is a protein that is...	05/31/2011
7951929	Insecticidal compounds and methods for selection thereof A series of potent and highly specific insecticidal toxins characterized by an amino acid sequences SEQ ID NO: 2-35. ...	05/31/2011
7939650	Stra6 polypeptides The present invention is directed to novel polypeptides having sequence similarity to Stra6, a murine retinoic acid responsive protein, and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nuclei...	05/10/2011

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Class 536/23.5 - Encodes an animal polypeptide