Class 536/23.2 - Encodes an enzyme

Subclass of Class 536 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which are DNA fragments which encode specific
No. of patents: 6435
Last issue date: 03/02/2010

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Number	Title	Issue Date
7671190	Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthases and accessory proteins, and uses thereof The invention relates to recombinant polyketide synthase enzymes, polyketide modifying proteins, and other proteins involved in polyketide biosynthesis or function. The invention provides domains of geldanamycin and herbimycin polyketide synthases, polynucleotides t...	03/02/2010
7671189	Enzymes having dehalogenase activity and methods of use thereof The invention relates to haloalkane dehalogenases and to polynucleotides encoding the haloalkane dehalogenases. In addition methods of designing new dehalogenases and method of use thereof are also provided. The dehalogenases have increased activity and stability at...	03/02/2010
7671188	Cellulose synthase from pine and methods of use The present invention concerns isolated polynucleotides that encode a polypeptide with cellulose synthase activity and methods of producing a plant that expresses the cellulose synthase-encoding polynucleotides and thereby has a different phenotype compared to a non...	03/02/2010
7667017	Isolated mevalonate pathway enzyme nucleic acids Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl...	02/23/2010
7662946	Sequences encoding genes and proteins The present invention relates to a disintegrin and metalloproteinase containing thrombospondin 1-like domains (ADAMTS) and in particular to a novel ADAMTS13 protease and to nucleic acids encoding ADAMTS13 proteases. The present invention encompasses both native and ...	02/16/2010
7662945	Neostatins The invention provides fragments of type XVIII collagen termed neostatins, and methods for their use in the treatment of ophthalmological disorders associated with angiogenesis. ...	02/16/2010
7655780	Integrin-linked kinase and its uses ILK genetic sequences and methods of use are provided. In some embodiments, a fragment or portion of an ILK polynucleotide is provided, where the polynucleotide has a sequence consisting of contiguous nucleotides within the provided ILK sequences, which may be withi...	02/02/2010
7638617	Enzymatic production of glycolic acid Various methods are provided for the enzymatic production of glycolic acid from glycolonitrile. These methods include: 1) use of Acidovorax facilis 72W nitrilase mutants having improved nitrilase activity for converting glycolonitrile to glycolic acid, and 2)...	12/29/2009
7638616	Variants of beta-glucosidase The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 ...	12/29/2009
7629451	Acid fungal proteases The present invention is directed to novel acid proteases and more specifically to NSP24 family proteases and NSP25 family proteases including biologically active fragments thereof and to nucleic acid molecules encoding said proteases. Also provided are vectors and ...	12/08/2009
7629450	PUFA polyketide synthase systems and uses thereof Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from the bacterial microorganisms Shewanella japonica and Shewanella olleyana, and biologically active fragments and homologues thereof. More particularly, t...	12/08/2009
7626009	PUFA polyketide synthase systems and uses thereof Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from the bacterial microorganisms Shewanella japonica and Shewanella olleyana, and biologically active fragments and homologues thereof. More particularly, t...	12/01/2009
7619077	Nucleic acids encoding a galacturonosyl tranferase enzyme (GALAT1) from The invention provides an isolated nucleic acid molecule encoding the polypeptide GALAT1 having galacturonosyltransferase (GalAT) activity. The Arabidopsis GALAT1 sequence disclosed represents the first pectin biosynthetic glycosyltransferase gene isolated fr...	11/17/2009
7608702	PUFA polyketide synthase systems and uses thereof The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding bi...	10/27/2009
7608703	PUFA polyketide synthase systems and uses thereof The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding bi...	10/27/2009
7605245	PUFA polyketide synthase systems and uses thereof The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding bi...	10/20/2009
7605244	Gamma tocopherol methyltransferase coding sequence from and uses thereof The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with genes that encode polypeptides that have methy...	10/20/2009
7598365	Targeted DNA insertion in plants Methods and means are provided to improve targeted DNA insertion in plants using rare-cleaving “double stranded break” inducing enzymes. Also provided are improved I-SceI encoding nucleotide sequences. ...	10/06/2009
7595382	Gamma tocopherol methyltransferase coding sequences from and uses thereof The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with genes that encode polypeptides that have methy...	09/29/2009
7592436	Gene encoding a protein having aurone synthesis activity The present invention provides a protein having aurone synthase activity involved in the color of flowers such as snapdragons, a gene that encodes it, cDNA in particular, and its applications. This gene can give yellow color to the flowers of plants by introducing i...	09/22/2009
7585959	Feedback resistant acetohydroxy acid synthethase mutants The present invention provides nucleotide sequences coding for acetohydroxy acid synthetase (AHAS) mutants, the mutated enzymes themselves and a process for the fermentative production of branched-chain amino acids using these enzymes in specific hosts in which gene...	09/08/2009
7560539	PUFA polyketide synthase systems and uses thereof Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from the bacterial microorganisms Shewanella japonica and Shewanella olleyana, and biologically active fragments and homologues thereof. More particularly, t...	07/14/2009
7553951	Soybean isopentenyl transferase genes and methods of use Methods and compositions for modulating plant development are provided. Polynucleotide sequences encoding isopentenyl transferase (IPT) polypeptides are provided, as are the amino acid sequences of the encoded polypeptides. The sequences can be used in a variety of ...	06/30/2009
7553950	Chondroitinase ABC I polynucleotides The invention relates to chondroitinase ABC I and uses thereof. In particular, the invention relates to recombinant and modified chondroitinase ABC I, their production and their uses. The chondroitinase ABC I enzymes of the invention are useful for a variety of purp...	06/30/2009
7553952	Gamma tocopherol methyltransferase coding sequence identified in and uses thereof The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with genes that encode polypeptides that have methy...	06/30/2009
7538205	Regulation of human prostasin-like serine protease Reagents which regulate human prostasin-like enzyme activity and reagents which bind to human prostasin-like enzyme gene products can be used to regulate human prostasin-like enzyme activity. Such regulation is particularly useful for treating metastasis of malignan...	05/26/2009
7538204	Recombinant enzyme and uses therefor The present invention relates to an isolated nucleic acid molecule comprising a sequence of nucleotides encoding a β-ketoacyl ACP synthase II from a plant, or a variant, derivative, homolog or analog of said β-ketoacyl ACP synthase II. The invention also relates t...	05/26/2009
7528244	Regulators of apoptosis The invention provides methods and compositions relating to apoptosis regulating proteins, known as Casper proteins, and related nucleic acids. The proteins may be produced recombinantly from transformed host cells from the disclosed Casper encoding nucleic acid or ...	05/05/2009
7498427	Nucleotide sequences of a new class of diverged delta-9 stearoyl-ACP desaturase genes An isolated nucleic acid fragment encoding a diverged delta-9 fatty acid desaturase is disclosed. Also the construction of a chimeric gene encoding all or a portion of the diverged delta-9 fatty acid desaturase is disclosed, in sense or antisense orientation, wherei...	03/03/2009
7491807	Gene encoding a DNA repair enzyme and methods of use thereof An isolated nucleic acid molecule encoding a human DNA repair enzyme, MED1, is disclosed. Like other mismatch repair genes which are mutated in certain cancers, MED1, encoding nucleic acids, proteins and antibodies thereto may be used to advantage in genetic or canc...	02/17/2009
7485712	Protein kinase (NPK-110) The present invention relates to a DNA sequence encoding a novel neuronal protein kinase (NPK) which phosphorylates tau proteins as well as other microtubule associated proteins (MAPs) in positions crucial for the binding to microtubules. The invention further relat...	02/03/2009
7479552	Type-1 ribosome-inactivating protein The invention relates to a novel ribosome-binding protein derived from Bougainvillea spectabilis having a molecular weight of about 26,000 daltons by polyacrylamide gel electrophoresis under reducing and non-reducing conditions, a pI of about 9.0, and a speci...	01/20/2009
7476731	Variants of the alpha 1 subunit of human AMPK Variants of the α subunit of AMPK, nucleic acids encoding such variants, and methods for their use are provided. ...	01/13/2009
7476730	Sulfotransferase and DNA encoding the enzyme A glycosaminoglycan 6-O-sulfotransferase having an activity of transferring sulfate to a hydroxyl at position 6 of a glycosamine residue of a glycosaminoglycan, which has a ratio of relative activities to substrates satisfying completely desulfated N-acetylated (CDS...	01/13/2009
7468430	Transposase and method of gene modification A transposase encoded by the Tol2 element; a polynucleotide encoding the same; a method of modifying the gene structure of a cell (preferably a vertebrate cell) by using the above protein; a method of modifying the function of a cell by modifying the gene structure ...	12/23/2008
7465793	Synthetic Δ17 desaturase derived from and its use in making polyunsaturated fatty acids The present invention relates to Δ17 desaturases, which have the ability to convert ω-6 fatty acids into their ω-3 counterparts (i.e., conversion of arachidonic acid [20:4, ARA] to eicosapentaenoic acid [20:5, EPA]). Isolated nucleic acid fragments and recombinan...	12/16/2008
7456269	Alzheimer's disease secretase, APP substrates thereof, and uses thereof The present invention provides the enzyme and enzymatic procedures for cleaving the β secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays. An enzyme that cleaves the α-secretase site of APP...	11/25/2008
7456271	Glutamate 2,3-aminomutases and methods of use thereof There are provided nucleic acids, including isolated DNA molecules, which encode glutamate 2,3-aminomutase enzymes, polypeptides produced from such nucleic acids and methods of making the nucleic acids and polypeptides. There are further provided methods of producin...	11/25/2008
7456270	Δ6-desaturase genes and uses thereof The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 6 (i.e., “Δ6-desaturase”). In particular, Δ6-desaturase may be utilized, for example, in the conversion of linoleic acid to γ-li...	11/25/2008
7446188	Plant cyclopropane fatty acid synthase genes, proteins, and uses thereof The present invention provides cyclopropane fatty acid synthase genes and proteins, and methods of their use. The present invention encompasses both native and recombinant wild-type forms of the synthase, as well as mutants and variant forms, some of which possess a...	11/04/2008

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Class 536/23.2 - Encodes an enzyme