Class 536/16.9 - Purification or recovery

Subclass of Class 536 - Organic compounds -- part of the class 532-570 series
Definition: Processes which include separating the antibiotic(s) from
No. of patents: 36
Last issue date: 08/05/2008

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Number	Title	Issue Date
7407654	Antibiotics GE 81112 factors A,B,B1, pharmaceutically acceptable salts and compositions, and use thereof The invention relates to an antibiotic substances of microbial origin, arbitrarily denominated antibiotic GE 81112 factor A, factor B1 and factor B, which is produced by fermentation of Streptomyces sp. DSMZ 14386, the pharmaceutically acceptable salts and co...	08/05/2008
7375088	Polyene polyketides, processes for their production and their use as a pharmaceutical This invention relates to a new class of polyene polyketides, their pharmaceutically acceptable salts and derivatives, and to methods for obtaining the compounds. One method of obtaining these compounds is by cultivation of novel strains of Streptomyces aizunensi...	05/20/2008
7063976	Process for preparing beta-fructofuranosidase enzyme and a process for producing fructooligosaccharides A process for preparing beta-fructofuranosidase enzyme and a process for producing fructooligosaccharides, in which the preparation of the enzyme is obtained by cultivating the fungus Aspergillus niger, either wild or mutated, in a preferably semi-solid cultu...	06/20/2006
6693085	Macrolide compound JK Compound JK represented by the general formula (1): ##STR1## wherein R is H or --CH3 ; or a pharmaceutically acceptable salt thereof. Compound JK has an excellent antimicrobial activity even against resistant strains including MRSA and is useful as ...	02/17/2004
6391851	Hydrochlorides of vancomycin antibiotics and process for producing the same Process for producing a hydrochloride of a vancomycin antibiotic, comprising subjecting an aqueous solution of a hydrochloride of a vancomycin antibiotic to a primary freezing at from -1° C. to -20° C. for a time sufficient to grow ice crystals, to form...	05/21/2002
6388058	Method of purifying daunomycin The present invention relates to a method in which daunomycin is eluted from a hydrophobic porous synthetic resin carrier onto which daunomycin is adsorbed from crude daunomycin with a buffered aqueous solution containing a water-miscible organic solvent ...	05/14/2002
5942611	Process for natamycin recovery A new process for recovering high purity natamycin from fermentation broth containing natamycin comprises the steps of adjusting the pH of the broth to above about 10 and adding an amount of a water-miscible solvent, such as isopropanol, sufficient to dis...	08/24/1999
5712377	Glycosides isolated from pollen, their sugar-free decomposition products and derivatives thereof What are described are new glucosides and their sugar-free decomposition products, as well as synthetically produced derivatives, which can be used as active components of pharmaceutical compositions. The novel glucosides have been isolated from aqueous e...	01/27/1998
5639735	Antitumor antibiotic compounds: hayumicins and analogs thereof Hayumicin compounds, obtainable by cultivation of a strain of Actinomadura sp. designated ATCC 55432, and analogs of these compounds. The novel compounds have antitumor as well as antibiotic, particularly antibacterial, activity....	06/17/1997
5591438	Natamycin recovery A process for the recovery of high purity natamycin from fermentaion broth by extraction with methanol is disclosed. In one embodiment the process comprises the steps: (1) adding methanol to a natamycin feed stream comprising at least 2 g/L of solid suspe...	01/07/1997
5468849	Rebeccamycin analogs by tryptophan analogs feeding Addition of certain tryptophan analogs to the culture medium during fermentation of a rebeccamycin-producing strain of Saccharothrix aerocolonigenes results in production of new rebeccamycin analogs having advantageous antitumor properties....	11/21/1995
5441940	Process for the preparation of water soluble primycin and its components and pharmaceutical compositions containing them The invention relates to a process for the preparation of water soluble primycin and to the separation of its components of formulae (A1) and (A3) either as single components or as a mixture of the two components. According to the in...	08/15/1995
5360593	Heat sterilization of labile antibiotics Disclosed is a process for heat sterilizing pharmaceuticals, cosmetics, foodstuffs and other materials, which are labile to oxidation by atmospheric oxygen at elevated temperature and labile to other degradative changes through interaction with volatiles ...	11/01/1994
5270182	Antibiotic compounds and their production The novel compounds of formulas I and II ##STR1## have an antibiotic activity....	12/14/1993
5188945	Recovery process for antibiotics LL-E19020 alpha and beta The invention provides an improved process for the isolation and purification of antibiotics designated LL-E19020 alpha and beta which are derived from the microorganism Streptomyces lydicus ssp. tanzanius NRRL 18036. The invention is a method of recovery...	02/23/1993
5147860	TAN-1120, its derivatives, production and use thereof The present invention relates to a compound of the formula: ##STR1## wherein X is hydroxyl group or hydrogenatom, or a salt thereof. The compound (I) has an acitivity to inhibit angiogenesis, which is useful for prophylaxis and therapy of various dis...	09/15/1992
5108912	Antitumor antibiotics (LL-E33288 complex) Antibacterial and antitumor agents designated LL-E33288 complex and their production by new strains of Micromonospora echinospora spp. calichensis NRRL-15839, NRRL-15975 and NRRL-18149, are disclosed....	04/28/1992
5077398	Process for isolation of avermectin B1 components with improved purity and subsequent isolaton of B2 components This invention relates to a novel process for isolation and purification of avermectin compounds which are produced by the microorganism, Streptomyces avermitilis. The process disclosed herein involves two steps, namely, crude crystallization and recrysta...	12/31/1991
4996305	Process for producing the antibiotic and antitumor agents LL-E33288.epsilon . &3xb5;-Br Processes for producing antibacterial and antitumor agents designated LL-E33288&3xb5;I and LL-E33288&3xb5;-Br using triphenylphosphine or a sulfhydryl-containing reagent are disclosed. Processes for producing reductively aromatized derivatives of other an...	02/26/1991
4978748	Intermediate and process for producing the antibacterial and antitumor agents LL-E33288&3xb5;-I and LL-E33288Epsilon-Br Processes for producing antibacterial and antitumor agents designated LL-E33288&3xb5;-I and LL-E33288&3xb5;-Br using triphenylphosphine at ice bath temperature are disclosed. Novel intermediates prepared in the processes are also disclosed....	12/18/1990
4977143	Antibacterial and antitumor agents LL-E33288EPSILON-I and LL-E33288EPSILON-BR Antibacterial and antitumor agents designated LL-E333288&3xb5;-I and LL-E33288&3xb5;-Br and their production by strains of Micromonospora echinospora ssp. calichensis designated NRRL-15839, NRRL-15975 and NRRL-18149, are disclosed....	12/11/1990
4885275	Vancomycin-HCL solutions and the lyophilization thereof Gel-free concentrated aqueous formulations of vancomycin hydrochloride are provided which comprise the antibiotic salt at a concentration between about 12% and about 50% w/v and a gel-inhibiting compound, e.g., ethanol, at a concentration between about 1%...	12/05/1989
4861870	Process for purifying anthracyclinone glycosides by selective adsorption on resins Disclosed is a process for purifying an impure anthracyclinone glycoside by selective adsorption of a slightly acidic aqueous solution of an impure glycoside on at least one resin and subsequent de-absorption of the purified glycoside by elution with acid...	08/29/1989
4667024	Process for the preparation of purified vancomycin class antibiotics A novel process for the isolation and purification of vancomycin class antibiotics which utilized affinity chromatography by the formation of a sorption complex between the antibiotic and an immobilizing ligand selected from -D-alanyl-D-alanine or -X-D-al...	05/19/1987
4581166	Method for isolating and purifying antibiotics A process is proposed for the isolation and purification of antibiotics wherein an antibiotic containing solution is extracted with an extraction agent at a temperature of from 0° to 40° C. and at a pressure which lies between the critical pressure and ...	04/08/1986
4568740	Process for purifying Tylosin Disclosed is a process for purifying Tylosin by selective adsorption of the fermentation broth previously brought to 7.5-10.0 pH on polymeric resins and by subsequent deadsorption of the purified product with a aqueous-alcoholic or aqueous-acetonic soluti...	02/04/1986
4424344	2-N-Acylated and 2-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process Nickel salts are used to effect the regio-selective acylation and alkylation of the 2'-amino group of 4-O-substituted-2-deoxystreptamine containing aminoglycosides. The 2'-N-substituted derivatives of apramycin, certain ଱ or ଲ-(lower alkyl)apr...	01/03/1984
4424345	1-N-Acylated and 1-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process Zinc salts are used to effect the regio-selective acylation and alkylation of the 1-amino group of 4-O-substituted-2-deoxystreptamine-containing aminoglycosides. The 1-N-substituted derivatives of apramycin, 3'-hydroxyapramycin, certain ଱ or ଲ...	01/03/1984
4423211	Process for the whole broth extraction of avermectin A process for the whole broth extraction of avermectins wherein the pH of the whole broth is adjusted with mineral acid and then contacted with a solvent extractant so that the avermectic active component is taken up by the solvent. The now avermectin ric...	12/27/1983
4380625	Process for the preparation of purified aminoglycoside antibiotics The invention relates to an improved process for the isolation and purification of aminoglycoside antibiotics of Formula (I) as defined herein combining selective lipophilization of the compound of Formula (I) in the crude product obtained by fermentation...	04/19/1983
4308375	Method for purifying water-insoluble polyene antibiotics A method for purifying water-insoluble polyene antibiotics, such as amphotericin and nystatin, is provided which method includes the step of passing a mixture of the polyene antibiotic dispersed in methanol through an ion exchange column whereby gram posi...	12/29/1981
4252971	Chromatographic process A chromatographic process for separation of an aminoglycoside antibiotic from impurities. Illustratively, there is disclosed a chromatographic process for separation of the gentamicin complex (C1, C2 and C1a) from impuriti...	02/24/1981
4213966	Method for isolating polyether antibiotics A method is provided for recovering a polyether antibiotic, such as lonomycin, monensin or ionomycin from a fermentation broth, wherein the polyether is first extracted with a water-immiscible solvent, such as ethyl acetate, and the resulting extracts con...	07/22/1980
4189568	Antibiotic purification process Carminomycin 1, a known antibiotic, is obtained in a highly purified form from crude fermentation solids containing it by use of a novel multistep purification process involving solvent extraction, countercurrent distribution and adsorption chromatography...	02/19/1980
4137224	Process for the preparation of antibiotic W-10 complex and for the isolation of antibiotic 20561 and antibiotic 20562 therefrom A novel antibiotic complex exhibiting antifungal activity is produced by fermenting a novel species of bacteria from the genus Aeromonas, the bacterium being herein designated Aeromonas sp. W-10. The antibiotic complex is comprised of at least three and p...	01/30/1979
3986927	Process for the purification and sterilization of acidophilic biologicals by extreme acidification at cold temperatures Methods of sterilizing biologicals in which the biologicals are acidified to a pH of not higher than about 1.0, preferably 0.75 to about 0.5, and the acidified biologicals are stored at cold temperatures for a perod of time sufficient to inactivate microb...	10/19/1976

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Class 536/16.9 - Purification or recovery