Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 7935799 | Methods of treating diarrhea caused by small intestinal bacterial overgrowth Disclosed is a method of diagnosing irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, or Crohn's disease, which in... | 05/03/2011 |
| 7605240 | Methods of treating diarrhea and bloating caused by small intestinal bacterial overgrowth Disclosed is a method of diagnosing irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, or Crohn's disease, which in... | 10/20/2009 |
| 7482439 | Caprazene as novel compound and derivatives thereof, and caprazol as novel compound and derivatives thereof Caprazene and caprazol could be synthesized by hydrolysis of a caprazamycin. There could be synthesized a caprazene-1′″-amide derivative of the formula (II) and a caprazene-1′″-ester derivative of the formula (III) ... | 01/27/2009 |
| 7417129 | Combinatorial libraries of monosaccharides A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds involving the compound of formula I. ... | 08/26/2008 |
| 7407654 | Antibiotics GE 81112 factors A,B,B1, pharmaceutically acceptable salts and compositions, and use thereof The invention relates to an antibiotic substances of microbial origin, arbitrarily denominated antibiotic GE 81112 factor A, factor B1 and factor B, which is produced by fermentation of Streptomyces sp. DSMZ 14386, the pharmaceutically acceptable salts and co... | 08/05/2008 |
| 7375088 | Polyene polyketides, processes for their production and their use as a pharmaceutical This invention relates to a new class of polyene polyketides, their pharmaceutically acceptable salts and derivatives, and to methods for obtaining the compounds. One method of obtaining these compounds is by cultivation of novel strains of Streptomyces aizunensi... | 05/20/2008 |
| 7371733 | Anti bacterial compounds The invention relates to novel paranmycin compounds that have activity against gram positive and gram negative bacteria, preferably bacteria that are resistant to other antibiotics. Paranmycins are of the general formula ... | 05/13/2008 |
| 7368431 | Polypeptide, the conjugate thereof with doxorubicine and a pharmaceutical composition based thereon The inventive polypeptide is embodied in the form of a similar fragment of the epidermal growth factor of aminoacid ranging from 21 to 31 and capable of efficiently binding with the receptor of the epidermal growth factor as a vector for the directed supply of antic... | 05/06/2008 |
| 7365071 | Heterocyclic compounds, preparation process and intermediates, and use as medicaments, in particular as β-lactamase inhibitors and antibacterials The invention relates to novel heterocyclic compounds of general formula (I) and to their salts with a base or an acid: The invention also relates to processes and to intermediates for the preparation of these compounds, and ... | 04/29/2008 |
| 7358232 | Method for the antibiotic coating of bodies with interconnecting microcavities as well as coated bodies and their usage The invention relates to a method for the antibiotic coating of bodies with interconnecting microcavities as well as bodies coated this way and their usage. The invented method is characterized in that in the microcavities of non-metallic bodies an aqueous solution ... | 04/15/2008 |
| 7331920 | Glycopeptide antibiotics, combinational libraries of glycopeptide antibiotics and methods of producing same Methods for preparing a glycopeptide are disclosed. The methods comprise the steps of selecting a protected glycopeptide of the formula A1-A2-A3-A4-A5-A6-A7, wherein the groups A1 | 02/19/2008 |
| 7300921 | Polyene polyketides and methods of production Novel polyene polyketides, their pharmaceutically acceptable salts, prodrugs and derivatives have been found to have antibiotic activity. One method for obtaining the compounds is by cultivation of Amycolatopsis orientalis ATCC™ 43491 or a mutant or variant... | 11/27/2007 |
| 7291410 | Orientation independent liquid fuel reservoir A fuel reservoir for a liquid fuel cell particularly useful for portable electronic devices or for a reformer, includes (a) a container defining a volume for holding a liquid fuel; (b) a wicking structure positioned within the volume and into which at least one port... | 11/06/2007 |
| 7285653 | Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis The present invention relates to nucleic acid coding for enzyme activities of spinosyn biosynthesis and to the relevant enzymes per se. Furthermore, the invention relates to methods for preparing spinsoyn derivatives and spinosyn precursors. ... | 10/23/2007 |
| 7259141 | Vancomycin analogs and methods thereof The present invention provides vancomycin analogs and methods related to synthesis of these analogs via chemoenzymatic techniques. In a preferred embodiment, the vancomycin analogs have a structural moiety selected from the group consisting of: | 08/21/2007 |
| 7244712 | Aminoglycoside antibiotics and methods of using same The present invention relates to aminoglycoside compounds having antibiotic activity. Moreover, the present invention relates to L-aminoglycoside compounds and diastereomers thereof which posses antibiotic activity and are not susceptible to development of resistant... | 07/17/2007 |
| 7241595 | Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates The present invention relates to glycosyl-etoposide prodrugs, a process for the preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates for treating cancers. ... | 07/10/2007 |
| 7220727 | Aminoglycosides as antibiotics The present invention provides aminoglycosides and pharmaceutical compositions that include the aminoglycosides. The aminogylcosides are useful to treat or prevent infectious diseases (e.g., bacterial infections) in a mammal (e.g., human). ... | 05/22/2007 |
| 7166270 | Methods of screening compounds useful for prevention of infection or pathogenicity Screening procedures are disclosed for identifying compounds useful for inhibiting infection or pathogenicity. Methods are also disclosed for identifying pathogenic virulence factors. ... | 01/23/2007 |
| 7128897 | Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis Pharmaceutical compositions are described that contain one agent for treatment of sinusitis and a surfactant. The compositions are prepared to have a surface tension that renders the composition effective for treatment of sinusitis. ... | 10/31/2006 |
| 7034130 | Method for producing novel spinosyn derivatives The present invention relates to methods for producing novel spinosyn derivatives which are substituted with a 1-hydroxy-ethyl radical in the C-21 position and to novel spinosyn derivatives of this type per se and to their use for producing novel spinosyns. ... | 04/25/2006 |
| 7030093 | Antibiotic coating for porous bodies and method for its production as well as its use The invention describes an antibiotic coating for porous bodies and its use. Into the porous system of non-metallic porous bodies and of metallic porous bodies, a coating made of at least one antibiotic salt that is hardly soluble in water or in an aqueous environme... | 04/18/2006 |
| 7001903 | Synergistic insecticidal mixtures The invention relates to insecticidal mixtures of spinosyns and agonists or antagonists of nicotinic acetylcholine receptors for protecting plants against attack by pests. ... | 02/21/2006 |
| 6994932 | Liquid fuel reservoir for fuel cells The present invention concerns a fuel reservoir for a liquid fuel cell particularly useful for portable electronic devices in which the fuel reservoir can deliver the liquid fuel regardless of the orientation. The fuel reservoir comprises (a) a container defining a ... | 02/07/2006 |
| 6967242 | Antimicrobial 2-deoxystreptamine compounds The present invention is directed to analogs of aminoglycoside compounds of the class having a glycosylated 2-deoxystreptamine (2-DOS) ring as well as their preparation and use as prophylactic or therapeutics against microbial infection. Compounds of the invention c... | 11/22/2005 |
| 6927210 | Ectoparasiticidal aqueous suspension formulations of spinosyns The invention provides a stable ectoparasiticidal aqueous suspension formulation of a spinosyn, comprising the spinosyn, or a physiologically acceptable derivative or salt thereof, milled to an average particle size of 1 to 15 microns, a surfactant in an amount effe... | 08/09/2005 |
| 6906040 | Method for reducing toxicity of combined chemotherapies Compositions and methods are provided for use in the treatment of cancer. ... | 06/14/2005 |
| 6867230 | Hygromycin A derivatives This invention relates to compounds of the formula and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R2, R3 and R10 | 03/15/2005 |
| 6858589 | Methods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria The invention provides a method of potentiating the activity of antibacterial agents that act on bacterial cell walls, comprising the step of administering to a subject an antibacterial agent and an aminoglycoside to attain a peak concentration of at least 4 mg/l of... | 02/22/2005 |
| 6841661 | Glycopeptide antibacterial compounds, compositions containing same and methods of using same The present invention relates to vancomycin analogs in which the vancosamine residue is substituted with a lipid-like substituent that includes a first aryl moiety and a second aryl moiety joined together by a flexible linker moiety, that is not a single bond direct... | 01/11/2005 |
| 6812331 | Aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments A subject of the invention is the compounds of formula (I): R1═H, OH, alkyl, alkenyl or alkynyl optionally substituted or alkoxy, R2═H, Hal, ... | 11/02/2004 |
| 6759523 | Antimicrobial 2-deoxystreptamine compounds The present invention is directed to analogs of aminoglycoside compounds of the class having a glycosylated 2-deoxystreptamine (2-DOS) ring as well as their preparation and use as prophylactic or therapeutics against microbial infection. Compounds of the invention c... | 07/06/2004 |
| 6756489 | Substituted tetrahydropyrane derivatives, method for producing same, their use as medicine or diagnostic agent, as well as medicine containing same Substituted tetrahydropyran derivatives, processes for their preparation, their use as a pharmaceutical or diagnostic, and pharmaceutical comprising them. The invention relates to compounds of the formula I in which the ... | 06/29/2004 |
| 6709679 | Antineoplastic conjugates of transferin, albumin and polyethylene glycol Conjugates of transferrin, albumin and polyethylence glycol consisting of native or thiolated transferrin or albumin or of polyethylene glycol (MW between approximately 5,000 and 20,0000) with at least one HS—, HO— or H2N group and cytostatic compound... | 03/23/2004 |
| 6699836 | Vancomycin analogs Compounds that are vancomycin analogs bearing terminal carboxyl group modifications as well as modifications to the vancosamine nitrogen and, optionally, modifications to the C6 position of the glucose residue attached to the amino acid four of the vancom... | 03/02/2004 |
| 6693085 | Macrolide compound JK Compound JK represented by the general formula (1): ##STR1## wherein R is H or --CH3 ; or a pharmaceutically acceptable salt thereof. Compound JK has an excellent antimicrobial activity even against resistant strains including MRSA and is useful as ... | 02/17/2004 |
| 6683056 | O-aryl glucoside SGLT2 inhibitors and method ##STR1## wherein when Y is ##STR2## or heteroaryl; A is --O(CH2)m, S, --NH(CH2)m, or (CH2)n where n is 0-3 and m is 0-2; and R1 to R6 are as defined herein... | 01/27/2004 |
| 6562792 | Hygromycin derivatives The present invention relates to compounds of the formula 1 ##STR1## and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein X, Y, V, W1, W2, Z1 and Z2 are as defined herein. The inventi... | 05/13/2003 |
| 6548536 | Agent for inducing apoptosis Agents for inducing apoptosis comprising a tetrocarcin derivative represented by the following formula (I) or a salt thereof as an active ingredient (---- represents a single bond or a double bond; j and k represent 0 or 1; R1 to R3,... | 04/15/2003 |
| 6541456 | Antimicrobial 2-deoxystreptamine compounds The present invention is directed to analogs of aminoglycoside compounds of the class having a glycosylated 2-deoxystreptamine (2-DOS) ring as well as their preparation and use as prophylactic or therapeutics against microbial infection. Compounds of the ... | 04/01/2003 |