...During the Civil War, the Confederacy established its own Patent Office which issued 266 patents, a third of which concerned implements of war.
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| Number | Title | Issue Date |
| 7361743 | Lincomycin derivatives possessing antibacterial activity Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents.... | 04/22/2008 |
| 7256177 | Lincomycin derivatives possessing antibacterial activity Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents.... | 08/14/2007 |
| 7199106 | Lincomycin derivatives possessing antimicrobial activity Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including gram positive organisms, and may be useful antimicrobial agents.... | 04/03/2007 |
| 7199105 | Lincomycin derivatives possessing antibacterial activity Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Me... | 04/03/2007 |
| 7164011 | Lincomycin derivatives possessing antibacterial activity Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Me... | 01/16/2007 |
| 5182374 | Clindamycin phosphate synthesis An improved process for producing the antibiotic compound clindamycin phosphate through the use of novel intermediate, 7(S)-chloro-7-deoxylincomycin-2-bis(2,2,2-trichloroethyl)phosphochloridate and similar compounds.... | 01/26/1993 |
| 5091522 | Retinoic esters of D-desosamine, process for their preparation and their use in human or veterinary medicine and in cosmetic compositions Retinoic esters of D-desosamine have the formula ##STR1## wherein the ##STR2## radical is (all trans) retinoyl, (13 cis) retinoyl or etretinoyl, and R2 represents linear or branched alkyl having 1-24 carbon atoms; and the ... | 02/25/1992 |
| 5045533 | Retinoic esters of antibiotics and pharmaceutical and cosmetic compositions containing them All trans or 13-cis retinoic acid esters of macrolide and lincosamide antibiotics. These esters are useful in the therapeutic and cosmetic treatment of dermatosis and principally in the treatment of acne.... | 09/03/1991 |
| 5004729 | Aromatic esters of macrolidic and lincosamidic antibiotics and pharmaceutical and cosmetic compositions containing them Aromatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.... | 04/02/1991 |
| 5004730 | Polycyclic aromatic esters of macrolidic and lincosamidic antibiotics and pharmaceutical and cosmetic compositions containing them Polycyclic aromatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.... | 04/02/1991 |
| 5004731 | Unsaturated cycloaliphatic esters of macrolidic and lincosamidic antibiotics and pharmaceutical and cosmetic compositions containing them Unsaturated cycloaliphatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.... | 04/02/1991 |
| 5004732 | Polyaromatic esters of macrolidic and lincosamidic antibiotics and pharmaceutical and cosmetic compositions containing them Polyaromatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.... | 04/02/1991 |
| 5004733 | Esters of the etretinic type or related to macrolidic and lincosamidic antibiotics and pharmaceutical and cosmetic compositions containing said esters Esters of the etretinic type or related to macrolides and lincosamides are employed in the treatment of acne and psoriasis.... | 04/02/1991 |
| 5004734 | Diaromatic esters of macrolidic and lincosamidic antibiotics and pharmaceutical and cosmetic compositions containing them Diaromatic esters of macrolidic and lincosamidic antibiotics are employed in the treatment of acne.... | 04/02/1991 |
| 4895934 | Process for the preparation of clindamycin phosphate A method for the preparation of clindamycin phosphate by first preparing the novel intermediate, clindamycin phosphoryl benzylate. The method can be used to make other, structurally related compounds.... | 01/23/1990 |
| 4849515 | Clindamycin-2-phosphoryl benzylate A novel compound, also known as 7(s)-chloro-7-deoxylincomycin-2-phosphoryl benzylate, useful an an intermediate in the production of the antibiotic, clindamycin-2-phosphate.... | 07/18/1989 |
| 4710565 | Thesis of 7-halo-7-deoxylincomycins Process for preparing clindamycin and analogs thereof by reacting lincomycin or an analog thereof with a dimethylformamide and an excess of thionyl halide.... | 12/01/1987 |
| 4568741 | Synthesis of 7-halo-7-deoxylincomycins An improved process for preparing 7-halo-7-deoxylincomycins and analogs thereof. The compounds prepared have anti-bacterial activity.... | 02/04/1986 |
| 4430495 | Process for preparing lincomycin and clindamycin ribonucleotides Novel and useful ribonucleotides of analogs of the well known antibiotics lincomycin and clindamycin. These ribonucleotides are unexpectedly highly active against Streptococcus hemolyticus and Staphylococcus aureus in vivo. These ribonucleotides are prepa... | 02/07/1984 |
| 4393054 | Method of treating cardiac arrhythmia The 3-(5'-adenylate) of lincomycin- and clindamycin-type compounds in which the propyl hygric acid moiety has been replaced by different cyclic amino acids can be used to treat cardiac arrhythmia in humans and animals.... | 07/12/1983 |
| 4383109 | Lincomycin nucleotides Novel and useful ribonucleotides of analogs of the well known antibiotics lincomycin and clindamycin. These ribonucleotides are unexpectedly highly active against Streptococcus hemolyticus and Staphylococcus aureus in vivo.... | 05/10/1983 |
| 4091204 | Process for recovering lincomycin from fermentation beer A dry-down method for partially recovering biologically active substance from fermentation beers.... | 05/23/1978 |