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| Number | Title | Issue Date |
| 6833445 | Guanidinylation, guanidinoglycosides, uses, and methods of assaying their activity Provided are reagents and methods useful for the synthesis of guanidinylated compounds. Also provided are methods for assaying molecules, including guanidinylated molecules that modulate viral infection and replication. ... | 12/21/2004 |
| 6525182 | Guanidinylation, guanidinoglycosides, uses, and methods of assaying their activity Provided are reagents and methods useful for the synthesis of guanidinylated compounds. Also provided are methods for assaying molecules, including guanidinylated molecules that modulate viral infection and replication.... | 02/25/2003 |
| 6500936 | Pluraflavins and derivatives thereof, process for their preparation and use thereof The invention relates to a compound of formula (I) ##STR1## wherein R1 is a sugar; R2 is --CH2 --O--(R7)m, R7 representing a sugar, or is --COOH; R3 is an epoxide-comprising group, or is C | 12/31/2002 |
| 6403777 | Metalloligands for cleaving nucleic acids Transition metal complexes, referred to hereinafter as "metalloligands", that catalyze the degradation of DNA and the cleavage of RNA at select sites are provided. In one embodiment, the metalloligand has the following structure: ##STR1## wherein R1 ... | 06/11/2002 |
| 5595977 | Salts of amino glycosides The present invention relates to novel amino glycoside salts of sucrose-octa-O-sulfonic acid of formula I: ([sucrose-octa-O-sulfonic acid8- ]-[R-(NH3+)x ]y -Mzn+) ... | 01/21/1997 |
| 5079234 | Inhibitors of aminoglycoside nephrotoxicity Certain water-soluble polyanionic organic acid polymers in the weight range of from about 1,000 to 30,000 daltons may be use to inhibit aminoglycoside nephrotoxicity. These polyanionic polymers are homopolymers or copolymers comprised of monomers selected... | 01/07/1992 |
| 5034515 | Staphylococcal fibronectin receptor, monoclonal antibodies thereto and methods of use A purified fibronectin receptor polysaccharide derived from Staphylococcus aureus is useful as an antigen for diagnostic tests and the preparation of monoclonal antibodies. The fibronectin receptor polysaccharide is prepared by gently removing expresed ma... | 07/23/1991 |
| 5030679 | Organic sulfide antioxidants and polymers stabilized therewith Organic sulfide antioxidants useful for stabilizing polyolefins against oxidative and thermal degradation during processing and use represented by Formula I: ##STR1## wherein n is an integer of 2 to 15; R is a substituted or unsubstituted alkyl group... | 07/09/1991 |
| 5003056 | Antibiotic NK86-0279, process for production of the same and application of the same This invention relates to an antibiotic NK86-0279 of the formula: ##STR1## which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.... | 03/26/1991 |
| 4617293 | Flavonoid phosphate salts of aminoglycoside antibiotics Flavonoid phosphates of aminoglycoside antibiotics are useful sparingly soluble salts, e.g., for achieving a depot effect.... | 10/14/1986 |
| 4593089 | Fluorescent polarization immunoassay utilizing substituted triazinylaminofluorescein aminoglycosides This disclosure relates to a method and reagents for determining ligands in biological fluids such as serum, plasma, spinal fluid, amnionic fluid and urine. In particular, this disclosure relates to a fluorescent polarization immunoassay procedure and to ... | 06/03/1986 |
| 4581166 | Method for isolating and purifying antibiotics A process is proposed for the isolation and purification of antibiotics wherein an antibiotic containing solution is extracted with an extraction agent at a temperature of from 0° to 40° C. and at a pressure which lies between the critical pressure and ... | 04/08/1986 |
| 4531000 | Processes for the preparation of branched, water soluble cellulose products A process for preparing n-amino-n-deoxy cellulose where n is 2 or 3 and has the same value at each occurrence in one molecule. When n is 2 cellulose is selectively oxidized by (a) reacting it with triphenylmethyl chloride; then (b) reacting the product fr... | 07/23/1985 |
| 4473557 | 3"-Deoxystreptomycin production thereof and pharmaceutical compositions containing same A new semi-synthetic antibiotic, 3"-deoxystreptomycin is now provided, which is useful as an antibacterial agent and is produced from 3"-deoxydihydrostreptomycin by a process comprising oxidizing the 3'-hydroxymethyl group of 2,5,6,4",6"-penta-O-acet... | 09/25/1984 |
| 4469683 | 3"-Epistreptomycin and its dihydro derivative, pharmaceutical compositions and production of the same New semi-synthetic antibiotics, 3"-epistreptomycin and 3"-epidihydrostreptomycin are now provided, which are useful as antibacterial agents. 3"-Epidihydrostreptomycin is produced by a process comprising hydrolyzing an appropriately N,O-protected 2",3... | 09/04/1984 |
| 4296203 | Xanthomonas bipolymer for use in displacement of oil from partially depleted reservoirs A mutant strain of the genus Xanthomonas produces a pyruvate-free biopolymer. This biopolymer and the deacetylated form of this new biopolymer provide mobility control solutions which are especially useful for enhanced oil recovery where high brine applic... | 10/20/1981 |
| 4268505 | Pharmaceutical composition comprising a nitrogen-containing polysaccharide and an antibiotic agent, and a method of treating an infectious disease therewith A nitrogen-containing polysaccharide, which is obtainable by extracting mycelia of a fungus belonging to the genus Coriolus of Polyporaceae of Basidiomycetes with an aqueous solvent, is effectively used in treating a bacterial infectious disease due to th... | 05/19/1981 |
| 4169197 | 6-Deoxyneamines aminoglycoside compounds 6-Deoxyneamine, 6-deoxy-5-epineamine, their 5-O-glycosyl derivatives, 6-deoxy-5-oxoneamine and the derivatives therefrom are useful as antibacterial agents and/or as intermediates in the synthesis of antibacterially active 6-deoxyneamines.... | 09/25/1979 |
| 4060682 | Process for the synthetic production of 3-deoxy derivative of an aminoglycosidic antibiotic 3'-Deoxy derivatives of neamine, 6'-N-alkylneamine, kanamycin B, 6'-N-alkylkanamycin B, ribostamycin, 6'-N-alkylribostamycin and paromamine may be produced by a new process comprising reducing the 3',4'--anhydro derivative (namely, the 3',4'-epoxid... | 11/29/1977 |
| 4029883 | Dehydroxylation of aminosugars Dehydroxylation of aminoglycoside antibiotics is carried out by halogenation of phosphorylated aminoglycoside antibiotics followed by reduction of thus halogenated antibiotics. The dehydroxylation process is entirely new and gives the final product in a h... | 06/14/1977 |
| 4002742 | 1-N-alkyl-4,6-di-(aminoglycosyl)-1,3-diaminocyclitols, methods for their manufacture, methods for their use as antibacterial agents, and compositions useful therefor 1-N-Alkyl-4,6-di-(aminoglycosyl)-1,3-diaminocyclitols, valuable as antibacterial agents, are prepared by treating an acid addition salt of a 4,6-di-(aminoglycosyl)-1,3-diamonocyclitol antibacterial agent in an inert solvent, preferably a protic solvent co... | 01/11/1977 |
| 3956275 | 2-Deoxystreptomycin A method of making new derivatives of streptomycin by mutational biosynthesis. A mutant of Streptomyces griseus makes streptomycin production dependent on streptidine addition. A new antibiotic, deoxystreptomycin, is disclosed.... | 05/11/1976 |
