Class 536/122 - Sulfur or halogen containing

Subclass of Class 536 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which include sulfur, fluorine, chlorine, bromine,
No. of patents: 320
Last issue date: 09/15/2009

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Number	Title	Issue Date
7589193	C-aryl glucoside SGLT2 inhibitors and method A compound of the formula I A method is also provided for treating diabetes and related diseases employing the above compound alone or in combination with another therapeutic agent. ...	09/15/2009
7417109	Polymers for delivering nitric oxide in vivo Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is prepared by reacting a polythiolated polymer with a nitro...	08/26/2008
7378519	Adduct of topiramate and tramadol hydrochloride and uses thereof Processes for isolation and purification of enantiomerically enriched compositions comprising tramadol and topiramate, and also for the subsequent isolation of 1S,2S-tramadol hydrochloride, are disclosed herein. ...	05/27/2008
7345166	Water soluble biodegradable polymeric photocatalysts Novel antenna polymers characterized by a polymeric background of a biodegradable water soluble polymer and chromophores chemically bonded to the polymeric background have been found to be useful as photocatalysts in aqueous media. On completion of the desired photo...	03/18/2008
7345117	Sulphated hyaluronic acid and sulphated derivatives thereof covalently bound to polyurethanes, and the process for their preparation The present invention relates to the synthesis of a haemocompatible polymer, consisting of a polyurethane bound covalently to sulphated hyaluronic acid. These sulfated derivatives have anticoagulative, non-thrombogenic, antiviral and anti-inflammatory properties. Th...	03/18/2008
7244830	Glycopolymers and free radical polymerization methods A glycopolymer composition is provided comprising glycopolymer molecules having a polymer backbone; a first pendent unit comprising a linking group connected to said polymer backbone and a saccharide moiety connected to said linking group, optionally a second penden...	07/17/2007
7189843	Production of carrageenan and carrageenan products The methods of the present invention prepare carrageenan products from processed seaweed material having a solids content of less than 25% by weight solids, using shear stress treatment. The carrageenan products comprise at least about 60% by weight of carrageenan a...	03/13/2007
7115586	Non-inclusion cyclodextrin complexes The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization of the active ingredient is enhanced by combining it with β-cyclode...	10/03/2006
7087709	Polymers for delivering nitric oxide in vivo Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is prepared by reacting a polythiolated polymer with a nitro...	08/08/2006
7087571	Alkyl polyglycoside derived sulfosuccinates The invention relates to a series of polyglycoside derivatives that contain water-soluble sulfosuccinate groups introduced into the molecule by reaction with the hydroxyl groups present in the starting polyglycoside molecule, with the chloro material. The preferred ...	08/08/2006
7084132	Artemisinins with improved stability and bioavailability for therapeutic drug development and application A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic ...	08/01/2006
7060685	Compounds and methods for inhibiting selectin-mediated function Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med...	06/13/2006
7049435	Extractive methods for purifying sucralose The present invention relates to novel extractive methods for purifying sucralose. The present invention also relates to compositions comprising the sucralose preparations made by the methods of the present invention. ...	05/23/2006
7022682	Method for the treatment of diabetes The present invention provides for a method for treatment and prevention of Type II Diabetes Mellitus and its complications comprising the step of administering to a patient a therapeutically-effective amount of Rhamnan Sulphate, its functional analogs, or its physi...	04/04/2006
7001893	Inclusion complex of Rifampicin, an anti-tubercular drug, with β-cyclodextrin or 2-hydroxypropyl β-cyclodextrin and a process thereof The present invention relates to an inclusion complex of Rifampicin and cyclodextrin (CD) that can be used as an anti-tubercular drug. The present invention also relates to a process for synthesizing inclusion complexes of the anti-tubercular drug, Rifampicin, with ...	02/21/2006
6998480	Process for improving sucralose purity and yield This invention relates to processes for purifying sucralose by the use of an initial non-crystallization purification procedure followed by three or more sequential crystallization steps and recycle of the mother liquor remaining from each crystallization step to th...	02/14/2006
6984732	High-intensity sweetener composition and delivery of same A composition for sweetening ingestable solids or liquids. The composition is compressed and comprises less than about 7.5 weight-% sucralose and one or more diluents. The composition is compressed at a pressure of greater than 2 pounds per square inch. A method of ...	01/10/2006
6951934	Method for preparing functionalized β-(1,3)-glucan derivatives The present invention relates to a novel method of chemically preparing functionalized derivatives of β-(1,3)-glucans, enabling obtaining oligosaccharides which are free or which comprise specific groups such as, for example, sulphate, phosphate, methyl, in pre-def...	10/04/2005
6951846	Artemisinins with improved stability and bioavailability for therapeutic drug development and application A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic ...	10/04/2005
6943248	Crystalline form of sucralose, and method for producing it A crystalline form of sucralose, and a method of making it. The method involves continuously crystallizing sucralose from an aqueous solution by a process providing continuous removal and recirculation of the vessel contents, and providing a long residence time for ...	09/13/2005
6927209	5-thio-β-D-xylopryanoside derivatives, preparation, method, pharmaceutical compositions containing them and their therapeutic use The present invention relates to novel compounds of formula (I): in which: R1, R2 and R3, which are identical or different, are each independently: a (...	08/09/2005
6923950	System and method for radiographic imaging of tissue System and method for radiographic imaging of tissue using a non-radioactive, radio-opaque imaging agent that accumulates intracellularly in tissue in proportion to its functional, or physiological, activity. In one embodiment, the imaging agent is a cell-membrane p...	08/02/2005
6906190	Inhibitors for de novo-RNA polymerases and methods of identifying targets for same A polymerase inhibitor has first moiety coupled to a second moiety via an optional linker in which the first moiety binds to an initiation nucleotide binding site of a polymerase and forms at least two hydrogen bonds with an RNA template strand that is associated wi...	06/14/2005
6891035	Process for bulk autoclaving Process for bulk autoclaving of polysaccharides, wherein the process includes: a) dissolving the polysaccharides in an aqueous solution and mixing until a homogeneous solution is obtained; b) filling the resulting solution in at least one container; c) placing the f...	05/10/2005
6875840	Polymers for delivering nitric oxide in vivo Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is prepared by reacting a polythiolated polymer with a nitro...	04/05/2005
6844329	Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing avidin or streptavidin which makes it possible to neutralize these polys...	01/18/2005
6828334	Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition The present invention relates to pharmaceutical compositions containing fenofibrate in the form of an inclusion complex with cyclodextrin, having high dissolution profile and in vivo enhanced bioavailability as compared with plain micronized fenofibrate compositions...	12/07/2004
6812223	Crystalline glucosamine sulfate metal salts and processes for preparing the same The present invention relates to novel crystalline glucosamine sulphate metal salts for use in the treatment of acute and chronic forms of rheumatic and arthritic diseases and of all the pathological conditions originating from metabolic disorders of the osteo-artic...	11/02/2004
6809198	Sucralose composition and process for its preparation The present invention provides an improved form of sucralose and a process for making it. ...	10/26/2004
6720419	Sulfated fucan oligosaccharide A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same. ...	04/13/2004
6673891	Polymers for delivering nitric oxide in vivo Disclosed are novel polymers derivatized with at least one --SNO group per 1200 atomic mass unit of the polymer. In one embodiment, the S-nitrosylated polymer has stabilized --S-nitrosyl groups. In another embodiment the S-nitrosylated polymer prepared by...	01/06/2004
6670338	Pentasaccharides processes for their preparation and pharmaceutical compositions containing them Pentasaccharides in acidic form and their pharmaceutically acceptable salts, the anionic form thereof having the formula: ##STR1## wherein: R represents hydrogen or an --SO3-, (C1 -C3)alkyl or (C2...	12/30/2003
6660722	Therapeutical treatments Therapeutical method comprising administration to a patient of an effective amount of especially soluble laminarin for the treatment of tumors and more generally of cancers of the group comprising breast cancer, lung cancer, oesophagus cancer, stomach can...	12/09/2003
6656922	Oral delivery of macromolecules Polysaccharides, which are widely used as an anticoagulation drugs, especially heparin, are clinically administered only by intravenous or subcutaneous injection because of their strong hydrophilicity and high negative charge. Amphiphilic heparin derivati...	12/02/2003
6642366	Process for making morphine-6-glucuronide and its analogues using haloglucuronate ester intermediates A process for manufacturing morphine-6-glucuronide and related compounds of the general structure of Formula 1: ##STR1## wherein optionally substituted morphine is conjugated with an optionally substituted member of a new class of intermediates, namely, ...	11/04/2003
6638916	Use of sulfated oligosaccharides as inhibitors of cardiovascular disease A method for the inhibition of vascular smooth muscle cell hyperplasia in a human or other warm-blooded animal patient in need of such treatment, comprises administration to the patient of an effective amount of at least one sulfated oligosaccharide, wher...	10/28/2003
6627744	Synthesis of glycodendrimer reagents The present invention relates to a chemically modified mutant protein including a cysteine residue substituted for a residue other than cysteine n a precursor protein, the substituted cysteine residue being subsequently modified by reacting the cysteine r...	09/30/2003
6627751	Hydrophobically modified anionic cellulose ethers A hydrophobically modified anionic cellulose ether obtainable by a process comprising reacting an alkali metal cellulose with at least three alkylating reagents A, B, and C. Reagent A is selected from the group of haloacetic acids, alkali metal haloacetat...	09/30/2003
6589943	Formulation of amphiphilic heparin derivatives for enhancing mucosal absorption Formulations for enhanced mucosal absorption of heparin are disclosed. In one embodiment, a powdered heparin composition is made by dissolving an amphiphilic heparin derivative including heparin covalently bonded to a hydrophobic agent in a water phase, d...	07/08/2003
6528497	Synthetic polysaccharides, their method of production and pharmaceutical compositions containing same Novel synthetic polysaccharides for use in the treatment of pathologies associated with a coagulation dysfunction....	03/04/2003

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Class 536/122 - Sulfur or halogen containing