Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 7271158 | Treatment of rumen acidosis with α-amylase inhibitors The invention described herein relates to: the use of an effective inhibitor of a bacterial α-amylase and/or α-glucosidase in the manufacture of a composition for the treatment of acidosis; a method of treatment of rumen acidosis which comprises administration of ... | 09/18/2007 |
| 7189843 | Production of carrageenan and carrageenan products The methods of the present invention prepare carrageenan products from processed seaweed material having a solids content of less than 25% by weight solids, using shear stress treatment. The carrageenan products comprise at least about 60% by weight of carrageenan a... | 03/13/2007 |
| 7148200 | Method for treating cancer A method for treating a cancer. The cancer excluding an adenocarcinoma and being epithelioma, glioma, sarcoma, melanoma, lymphoma or leukemia; or the cancer is an adenocarcinoma cancer excluding colon cancer, lung cancer and gastric cancer. The method comprises admi... | 12/12/2006 |
| 7071327 | Polysaccharide-based superabsorbent film A superabsorbent polysaccharide can be obtained by crosslinking a polysaccharide or derivative thereof with at least 1% by weight of a flexible spacer having a chain length of at least 9 chain atoms and having terminal activated coupling groups. The flexible spacer ... | 07/04/2006 |
| 7060685 | Compounds and methods for inhibiting selectin-mediated function Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 06/13/2006 |
| 7056898 | Hypersulfated disaccharides and methods of using the same for the treatment of inflammations Provided are compounds and compositions thereof that are useful for treating inflammation, particularly pulmonary inflammations including asthma and asthma-related pathologies such as allergy. Also provided are methods for using such compounds and compositions of th... | 06/06/2006 |
| 7034054 | Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols The present invention provides method for the treatment of a symptom of neuronal damage associated with cerebral ischemia comprising administering gamma-, beta-, or delta-tocopherol enriched tocopherol compositions. ... | 04/25/2006 |
| 7022684 | Treatment of rumen acidosis with α-amylase inhibitors The invention described herein relates to: the use of an effective inhibitor of a bacterial α-amylase and/or α-glucosidase in the manufacture of a composition for the treatment of rumen acidosis; a method of treatment of rumen acidosis which comprises administrati... | 04/04/2006 |
| 7019131 | Programmable one-pot oligosaccharide synthesis The reactivity of a number of p-methylphenyl thioglycoside (STol) donors which are either fully protected or have one hydroxyl group exposed has been quantitatively determined by HPLC in conjunction with the development of a broadly applicable approach for a facile ... | 03/28/2006 |
| 6969531 | Sodium hyaluronate microspheres The present invention relates to microspheres comprising hyaluronan derivatized with a bifunctional crosslinker to form microspheres. Methods of making such microspheres, comprising mixing hyaluronic acid and a dihydrazide with a crosslinker in an aqueous solution, ... | 11/29/2005 |
| 6927289 | Sulfated fucan oligosaccharide A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same. ... | 08/09/2005 |
| 6919316 | Immunosuppressive agent An immunosuppressive agent comprising, as an effective ingredient, at least one compound selected from the group consisting of compounds represented by general formula (1) below and pharmaceutically acceptable salts thereof: | 07/19/2005 |
| 6867194 | Enzyme activated nitric oxide donors Sugar-modified SIN-1 compositions are provided. The compositions are useful for generating NO in response to hydrolytic activity of a glycosidase specific for the O-glycosidic bond between the sugar and SIN-1 moieties. Pharmaceutical compositions containing the suga... | 03/15/2005 |
| 6844328 | Polysaccharidic esters of N-derivatives of glutamic acid The present invention is related to polysaccharide esters of N-derivatives of glutamic acid (N-GA derivatives). These polysaccharidic esters have antiproliferative activity and are characterized by a low systemic toxicity. The esters of the invention are used in the... | 01/18/2005 |
| 6770629 | Administration of a sulfopyranosylacylglycerol to treat certain cancers A medicament containing at least one compound selected from the group consisting of compounds represented by General formula (1): wherein R101 represents an acyl residue of an unsaturated higher fatty acid, an... | 08/03/2004 |
| 6767898 | Methods for using specific saccharides for treating alzheimer's disease and other amyloidoses A pharmaceutical agent for treating an amyloid disease in a patient, wherein the pharmaceutical agent comprises a glucose monosaccharide containing at least one anionic group, or a pharmaceutically acceptable salt thereof. The agent is directed to amyloid diseases i... | 07/27/2004 |
| 6759522 | Sulforhamnosylacyglycerol derivatives and use thereof as medicaments Novel sulforhamnosylacylglycerol derivatives represented by General Formula (1): where R101 represents an acyl residue of a higher fatty acid and R102 represents a hydrogen atom or an acyl residue o... | 07/06/2004 |
| 6740640 | Sulfofucosylacylglycerol derivatives and administration thereof as medicaments Sulfofucosylacylglycerol derivatives represented by General Formula (1): where R101 represents an acyl residue of a higher fatty acid and R102 represents a hydrogen atom or an acyl residue of a high... | 05/25/2004 |
| 6720419 | Sulfated fucan oligosaccharide A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same. ... | 04/13/2004 |
| 6686341 | Nutritional compositions which contain slightly negatively charged, non-digestible polysaccharides and use thereof for reducing transport through tight junctions A nutritional composition which contains slightly negatively charged non-digestible polysaccharides having a molecular weight of 8 kD to 40,000 kD, characterized in that the rise in the viscosity of the composition caused by the polysaccharides is less th... | 02/03/2004 |
| 6680304 | Disaccharides with anti-arthrosic properties The invention relates to novel disaccharides of formula (I), wherein R1 is selected from the group consisting of hydrogen, linear or branched (C1 -C4) alkyl, phenylalkyl with less than ten carbon atoms and --COCH3 | 01/20/2004 |
| 6664243 | Benzyllactobionamides as inhibitors of smooth muscle cell proliferation This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure ##STR1## wherein R1 -R13 are as defined herein.... | 12/16/2003 |
| 6632801 | Method and composition for inhibiting human cholesterol esterase A method and composition for inhibiting human cholesterol absorption comprising ingesting a therapeutic amount of an inhibitor of human cholesterol esterase comprising very high molecular weight sulfated polysaccharide having a sulfate to monomer ratio of... | 10/14/2003 |
| 6627744 | Synthesis of glycodendrimer reagents The present invention relates to a chemically modified mutant protein including a cysteine residue substituted for a residue other than cysteine n a precursor protein, the substituted cysteine residue being subsequently modified by reacting the cysteine r... | 09/30/2003 |
| 6590097 | Sulfated fucogalactan Sulfated fucogalactan or its salt useful as a reagent for sugar chain engineering or an HGF-production inducer; a degraded product or its salt obtained by treating the sulfated fucogalactan with a sulfated fucogalactan digesting enzyme; the sulfated fucog... | 07/08/2003 |
| 6570009 | Region-selective method for preparing cyclodextrin C-6 monosulphonyl derivatives The invention relates to a highly regioselective method for preparing a derivative of cyclodextrin, ଲ-cyclodextrin in particular, monosulfonylated at C-6, in which said cyclodextrin is caused to react with a sulfonylation agent, in an alkaline aqueo... | 05/27/2003 |
| 6528497 | Synthetic polysaccharides, their method of production and pharmaceutical compositions containing same Novel synthetic polysaccharides for use in the treatment of pathologies associated with a coagulation dysfunction.... | 03/04/2003 |
| 6518248 | Method of treating gastric or colon cancer by administration of a sulfoquinovosylacylglycerol ester An anticancer drug includes a compound represented by Formula (1): ##STR1## where R101 represents an acyl moiety of a saturated higher fatty acid, and R102 represents a hydrogen atom or an acyl moiety of a saturated higher fatty acid... | 02/11/2003 |
| 6518302 | Remedies ##STR1## Compounds represented by general formula (I) wherein X represents OH or OSO3 H; and R represents a substituent other than OH which allows, after leaving, the induction of unsaturated bonds into the 3- and 4-positions of 3,6-anhydrogala... | 02/11/2003 |
| 6518410 | Sulfoquinovosylacylglycerol derivative, and use thereof as medicaments A method for immunosuppression in a subject comprising administering to the subject in need thereof, a pharmaceutically effective amount of at least one sulfoquinovosylacylglycerol derivative represented by General formula (1-1): ##STR1## wherein R | 02/11/2003 |
| 6495678 | Immunosuppressant containing glucopyranose derivative as active ingredient An immunosuppressant comprising Glucopyranose derivatives of the formula (I): ##STR1## wherein R is H, OH etc; G is --CH2 CH(R1 --R2)(R3 --R4), in which R1 is a single bond, OCO-alkyl; R | 12/17/2002 |
| 6462215 | Sulfonation, sulfation, and sulfamation A process that can be used for sulfonating, sulfating, or sulfamating an organic compound is disclosed. The process can comprise, consist essentially of, or consist of, contacting the organic compound with sulfur trioxide under a condition sufficient to e... | 10/08/2002 |
| 6444795 | 1-0-(2-propenyl)-6-0-sulfonylpyranosides 1-O-(2-propenyl)-6-O-sulfonylpyranoside represented by the formula ##STR1## wherein R1, R2 and R3 each independently represents an alkyl or substituted silyl group, and R4 represents an alkylsulfonyl or arylsulf... | 09/03/2002 |
| 6395886 | 1-O-(2-propenyl)-6-deoxy-6-carbonylthiopyranosides 1-O-(2-propenyl)-6-deoxy-6-carbonylthiopyranoside represented by the formula ##STR1## wherein R1, R2 and R3 each independently represents an alkyl or a substituted silyl group, and R5 represents a hydrogen atom,... | 05/28/2002 |
| 6342367 | Method for the preparation of chondroitin sulfate compounds Disclosed is an economical method for the preparation of chondroitin sulfates A and C useful as an effective ingredient of medicaments from fish scales as a waste material discharged from fishery in large quantities. Fish scales are enzymatically decompos... | 01/29/2002 |
| 6229008 | -D-pentofuranosides, and a process for preparing the same -D-pentofuranoside derivatives have the general formula (D), in which R stands for (C1 -C4)alkyl that is non-substituted or substituted one or several times by halogen, (C1 -C4)alkyl, (C1 -C | 05/08/2001 |
| 6225450 | DNA sequencing by mass spectrometry The invention describes a new method to sequence DNA. The improvements over the existing DNA sequencing technologies are high speed, high throughput, no electrophoresis and gel reading artifacts due to the complete absence of an electrophoretic step, and ... | 05/01/2001 |
| 6207652 | Apoptosis inducers Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or de... | 03/27/2001 |
| 6207649 | Nucleoside analogs and uses in treating disease The invention relates to pharmaceutical compositions of nucleoside dimers containing an L-sugar in at least one of the nucleosides.... | 03/27/2001 |
| 6194192 | Method of purifying and removing viruses The present invention offers a method for the purification or removal of virus characterized in containing a step where the virus in the virus-containing sample is adsorbed with sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) th... | 02/27/2001 |
