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...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 7419793 | Flea octopamine receptor nucleic acid molecules, proteins and uses thereof The present invention relates to tick octopamine receptor nucleic acid molecules; to tick octopamine receptor proteins encoded by such nucleic acid molecules; to antibodies raised against such proteins; and to compounds that inhibit the activity of such proteins. Th... | 09/02/2008 |
| 7354993 | Insecticidal polypeptides and methods of use thereof The invention relates to isolated insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Methods of treating insects, insect larvae, and plants with the insecticidal polypeptides are al... | 04/08/2008 |
| 7259254 | Mutants and assay system to identify USP/RXR ligands The invention relates to mutant nuclear hormone receptors that encode mutant nuclear hormone receptors, in which particular amino acid residues are substituted with respect to wild type, so as to be able to detect ligand binding to the mutant receptor by either a ch... | 08/21/2007 |
| 7259145 | Mechanically activated channel blocker The present invention discloses a peptide of SEQ ID NO:1 and its variants that blocks stretch-activated ion channels. All amino acids in this peptide are D-amino acids. The peptide, designated as D-GsMTx4, is an enantiomer of a peptide GsMTX-4 present in the venom o... | 08/21/2007 |
| 7244837 | Insect monoamine transporter and methods of use thereof The present invention is directed to a lepidopteran octopamine/tyramine transporter. Nucleic acids encoding the transporter, and vectors and host cells comprising the nucleic acids are provided. The invention further provides a recombinant octopamine/tyramine transp... | 07/17/2007 |
| 7211652 | Protein from horn fly saliva that disrupts hemostasis Compositions and methods for preventing hematophagous infestation of cattle are provided, directed at isolated proteins that disrupt platelet aggregation. Also provided are nucleotide sequences encoding the proteins. The exemplary haematollogen protein was isolated ... | 05/01/2007 |
| 7211408 | Recombitope peptides The present invention provides peptides having T cell stimulating activity termed recombitope peptides. Recombitope peptides of the invention preferably comprise at least two T cell epitopes derived from the same or from different protein antigens, and more preferab... | 05/01/2007 |
| 7166693 | Ectoparasite saliva proteins The present invention is directed to a novel product and method for isolating ectoparasite saliva proteins, and a novel product and method for detecting and/or treating allergic dermatitis in an animal. The present invention includes a saliva protein collection appa... | 01/23/2007 |
| 7064184 | Mag1 antimicrobial polypeptides and their uses The methods and compositions of the present invention find use in impacting microbial pathogens and in enhancing disease resistance to pathogens, particularly by plants. The compositions of the invention include polypeptides that possess antimicrobial properties, pa... | 06/20/2006 |
| 7041808 | Antimicrobial proteins, genes encoding the proteins and method of using the same It is intended to provide thermotolerant and antimicrobial proteins having a broad antibacterial spectrum and being useful in the agricultural, medical and industrial field; and plants resistant to pathogenic microorganisms. Namely, DNAs comprising the base sequence... | 05/09/2006 |
| 6806358 | Peptide inhibitor of TGF-β growth factors A potent peptide inhibitor (SuperSog) of TGF-β family growth factor signalling, peptide variants thereof and nucleotide coding sequences therefor are provided by the invention. The Super-Sog peptide comprises a fragment of the Drosophilia short gastrulation (Sog) g... | 10/19/2004 |
| 6800290 | Variants of allergenic proteins of the group 2 of dermatophagoides Variants of allergens of Dermatophagoides pteronyssinus species with reduced allergenic activity. ... | 10/05/2004 |
| 6794360 | Treatment of allergic rhinitis The invention relates to the discovery that various proteins isolated from ticks are effective in the treatment and prevention of allergic rhinitis. These proteins may most suitably be applied to an effected area and are thus effective to treat this condition and to... | 09/21/2004 |
| 6787642 | Use of insect cell membrane transporters as novel target sites for inspection The present invention discloses the existence of novel insect transporters that can be used as targets for screening of new insecticides. This invention provides nucleic acids which encode the following insect cell membrane transporters: acetylcholine transporters, ... | 09/07/2004 |
| 6737399 | Treatment of conjunctivitis The present invention relates to the discovery that various proteins isolated from ticks are effective in the treatment of conjunctivitis. These proteins may most suitably be applied topically to an affected area and are effective to ameliorate the symptoms of this ... | 05/18/2004 |
| 6677443 | Insect monoamine transporter and methods of use thereof The present invention is directed to a lepidopteran octopamine/tyramine transporter. Nucleic acids encoding the transporter, and vectors and host cells comprising the nucleic acids are provided. The invention further provides a recombinant octopamine/tyra... | 01/13/2004 |
| 6653460 | Voltage-gated calcium channel antagonist and method A novel class of peptides selectively block class E voltage-gated calcium channels. The class is exemplified by HG peptides such as HG-1, which is isolated from the venom-producing cells of the tarantula Hysterocrates gigas. Also disclosed are methods of ... | 11/25/2003 |
| 6555109 | Analgesic from snake venom A substantially non-toxic fraction isolated from the venom of Vipera xanthina is disclosed which fraction has an analgesic effect. The fraction is preferably purified on an ion exchange column from Vipera xanthina palestinae. Also described are a pharmace... | 04/29/2003 |
| 6489140 | Flea ecdysone and ultraspiracle nucleic acid molecules, proteins and uses thereof The present invention relates to flea ecdysone receptor and ultraspiracle proteins; to flea ecdysone receptor and ultraspiracle nucleic acid molecules, including those that encode such flea ecdysone receptor and ultraspiracle proteins; to antibodies raise... | 12/03/2002 |
| 6432407 | Antigenic protein originating in malassezia A substantially pure, isolated, antigenic protein from fungi of the genus Malassezia, characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergoses; an antigenic fragment derived from the antigenic prot... | 08/13/2002 |
| 6406900 | Flea protease proteins, nucleic acid molecules and uses thereof The present invention relates to flea serine protease proteins and flea cysteine protease proteins; to flea serine protease and cysteine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins... | 06/18/2002 |
| 6358927 | Peptide fragments and analogs derived from PBAN 1-33 NH2 for controlling moths Synthetic peptide fragments from pheromone biosynthesis activating neuropeptide PBAN (1-33)-NH2 of Helicoverpa zea which have either pheromone biosynthesis stimulating or inhibiting activity.... | 03/19/2002 |
| 6316221 | Functional expression of pheromone binding protein A method which enable to provide sufficient amount of insect OBP, and moreover, to produce on a large scale under the condition of physiological activation is proposed. The functional expression of pheromone binding protein from B. mori, whereby it is exp... | 11/13/2001 |
| 6265376 | Insecticidal plectoxins from plectreurys tristis Novel plectoxins isolated from the Primitive Hunting Spider, Plectreurys tristis are described, and their amino acid sequences are presented. These are toxic to various groups of insects, including Lepidopterans. A particularly potent plectoxin is Plt-VI.... | 07/24/2001 |
| 6251862 | Insecticidal toxins from the parasitic wasp bracon hebeter Novel polypeptides are isolated from the venom of the parasitic wasp, Bracon hebetor, and are designated Brh-I to Brh-V. These polypeptides are paralytic and/or toxic to insects. The entire amino acid sequence of Brh-I and the DNA encoding it is also dete... | 06/26/2001 |
| 6235283 | DNA encoding a cell membrane glycoprotein of a tick gut This invention relates to an antigen isolated from the cattle tick Boophilus microplus and to the gene coding for that antigen and to the protein product of that gene. The antigen when used in part or in entirety as an immunogen administered to cattle as ... | 05/22/2001 |
| 6162430 | Insect control with multiple toxins A method is provided that accelerates the rate of kill of pests such as from the order Lepidoptera. The method comprises treating the pests or their loci with at least two different insect toxins which are expressed from at least one recombinant microbe. ... | 12/19/2000 |
| 6156726 | Voltage-gated calcium channel antagonist and method A novel class of peptides selectively block class E voltage-gated calcium channels. The class is exemplified by HG peptides such as HG-1, which is isolated from the venom-producing cells of the tarantula Hysterocrates gigas. Also disclosed are methods of ... | 12/05/2000 |
| 6106844 | Immunomodulatory peptides of vespid antigen 5 The present invention is directed to immunogenic peptides from vespid antigen 5. These immunogenic peptides can be used in immunotherapy for vespid venom allergic individuals. The present invention is thus directed to T cell epitopes of vespid antigen 5 t... | 08/22/2000 |
| 6074859 | Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein According to the present invention, there can be provided a bioluminescent protein, luciferase excellent in thermostability etc. and with high catalytic efficiency.... | 06/13/2000 |
| 6063902 | Ectoparasite histamine releasing factor, genes and uses thereof The present invention relates to ectoparasite histamine releasing factor (HRF) proteins; to ectoparasite HRF nucleic acid molecules, including those that encode such HRF proteins; to antibodies raised against such HRF proteins; and to compounds that inhib... | 05/16/2000 |
| 6034217 | Peptidoglycan recognition proteins and their production A gene coding for a peptidoglysan recognition peptide (PGRP) is cloned, a recombinant vector into which said gene is introduced is obtained, and a transformant transformed with said recombinant vector is cultivated, thereby producing the PGRP in large amo... | 03/07/2000 |
| 5958887 | Use of a hymenoptera venom for the manufacture of a medicament for treating DNA virus infections The present invention relates to the use of hymenoptera venom or proteinaceous or polypeptide components contained therein in the manufacture of a medicament for treating DNA virus infections, and to a method for treatment of mammalian DNA virus infection... | 09/28/1999 |
| 5955573 | Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same Stabilized ubiquitin-lytic peptide fusion polypeptides and a method of making the same by sub-cloning nucleic acid sequences coding for lytic peptides into a plasmid vector comprising a promoter and ubiquitin polypeptide coding sequence, wherein the ubiqu... | 09/21/1999 |
| 5904922 | Treatment with polyvalent antivenom containing immunoglobulin which is greater than 50% venom-reactive Antivenoms to snake, spider, scorpion and jelly fish venoms are produced for treatment of humans and animals, and for analytical use. Polyvalent antivenoms are produced containing immunoglobulin which is greater than fifty percent venom reactive. Purified... | 05/18/1999 |
| 5858970 | Polypeptide having Factor Xa inhibitory activity A novel polypeptide derived from the leech Hirudo medicinalis was found to be able to inhibit Factor Xa thereby reducing the extent of blood coagulation. The polypeptide is useful in treating conditions of excessive blood coagulation. A recombinant organi... | 01/12/1999 |
| 5827829 | Use of a hymenoptera venom for the manufacture of a medicament for treating DNA virus infections The present invention relates to the use of hymenoptera venom or proteinaceous or polypeptide components contained therein in the manufacture of a medicament for treating DNA virus infections, and to a method for the treatment of mammalian DNA virus infec... | 10/27/1998 |
| 5804201 | Immunomodulatory peptides of vespid antigen 5 The present invention is directed to immunogenic peptides from vespid antigen 5. These immunogenic peptides can be used in immunotherapy for vespid venom allergic individuals. The present invention is thus directed to T cell epitopes of vespid antigen 5 t... | 09/08/1998 |
| 5795857 | Mimetic insect pyrokinin analogs for insect control Novel pseudopeptide analogs of the insect pyrokinin neuropeptide family which possess biological activity mimicking that of the naturally occurring neuropeptides are disclosed. By addition of a hydrophobic moiety to an active portion of the pyrokinin pept... | 08/18/1998 |
| 5795862 | Ectoparasite saliva proteins and apparatus to collect such proteins The present invention is directed to a novel product and method for isolating ectoparasite saliva proteins, and a novel product and method for detecting and/or treating allergic dermatitis in an animal. The present invention includes a saliva protein coll... | 08/18/1998 |
