Quotables
"It is my heart-warmed and world-embracing Christmas hope and aspiration that all of us, the high, the low, the rich, the poor, the admired, the despised, the loved, the hated, the civilized, the savage (every man and brother of us all throughout the whole earth), may eventually be gathered together in a heaven of everlasting rest and peace and bliss, except the inventor of the telephone. "
Mark Twain ; Christmas greetings, 1890
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| Number | Title | Issue Date |
| 6541453 | Peptide derivatives Novel peptide derivatives, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing then are useful in treating MHC class II dependent T-cell method autoimmune or inflammatory diseases, such as rheumatoid arthritis.... | 04/01/2003 |
| 6509316 | Pharmaceutical compositions, methods, and kits for treatment and diagnosis of lung cancer The present invention relates to pharmaceutical compositions, methods and kits that provide for the early diagnosis and treatment of lung cancer. More particularly, the present invention relates to pharmaceutical compositions containing uteroglobin for pr... | 01/21/2003 |
| 6143867 | Human eosinophil-derived basic protein The present invention provides a human eosinophil-derived basic protein (EBPH) and polynucleotides which identify and encode EBPH. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences e... | 11/07/2000 |
| 6004586 | Molecule involved in binding of sperm to egg surfaces and procedures for use of this molecule to enhance or decrease potential fertility A purified polypeptide which provides for initial binding of sperm to oocyte investments and has an active amino acid sequence of SEQ ID NO:12 (Cys-Gln-Ser-Leu-Gln-Glu-Tyr-Leu-Ala-Glu-Gln-Asn-Gln-Arg-Gln-Leu-Glu-Ser-A sn-Lys-Ile-Pro-Glu-Val-Asp-Leu-Ala-Arg... | 12/21/1999 |
| 5969125 | Secreted proteins and polynucleotides encoding them Novel polynucleotides and the proteins encoded thereby are disclosed.... | 10/19/1999 |
| 5864011 | Cancer related antigen A method of determining the prognosis of a solid tumor is provided, in which a sample from a patient bearing a tumor is assayed for the presence of a protein which is immunologically cross-reactive with the hpr gene product, but not with haptoglobin 1 or ... | 01/26/1999 |
| 5783396 | Method of detecting rupture of the amniotic membranes in pregnant mammals The present invention relates to the method of detecting rupture of the amniotic membranes in pregnant mammals including humans using an immunoassay and reagents useful in such an assay. The method describes how to prepare a suitable protein antigen from ... | 07/21/1998 |
| 5690966 | Process for the preparation of an extract from human placenta containing glycosphingolipids and endothelin-like constituent peptides useful for the treatment of vitiligo A process for the preparation of an extract from human placenta containing glycosphingolipids and endothelin-like peptides useful for the treatment of vitiligo is disclosed.... | 11/25/1997 |
| 5580960 | KS-laminin and methods of use KS-laminin and a KS-laminin-kalinin adduct are disclosed. The molecules of the invention are useful for promoting the adhesion of keratinocytes to a substrate.... | 12/03/1996 |
| 5554595 | Selective regulation of B lymphocyte precursors by hormones Based on the discovery that normal pregnant mice have a striking reduction in committed precursors of B lymphocytes, which could be documented in mice as early as day 6 of gestation, when IL-7 responding colony forming cells were reduced as much as two-th... | 09/10/1996 |
| 5516754 | Method for the selective dissolution of cancer cells using a composition derived from the photosynthetic system of plants and mammalian embryonic tissue By the combined use of an agent which selectively dissolves tumor cells and which contains a protein fraction which has oxygen-liberating action and which is derived from the photosynthetic system of plants, together with a further agent which inhibits th... | 05/14/1996 |
| 5494899 | Selective regulation of B lymphocyte precursors by hormones It has been determined that estrogen and other hormones elevated in pregnancy induce a specific modulation of lymphocyte precursor cell production. The immune system of an animal or bone marrow cells in culture can therefore be modulated in a specific man... | 02/27/1996 |
| 5391380 | Thromboplastin extract, reagent, and preparation thereof A thromboplastin extract including an aqueous thromboplastin extract of a powdered thromboplastin source including a metal ion chelator. A thromboplastin reagent for use in blood coagulation tests, the thromboplastin reagent includes the extract and calci... | 02/21/1995 |
| 5352668 | Product and method for improving keratinocyte adhesion to the dermis A purified protein kalinin is disclosed that provides adhesion between epidermal keratinocytes and the underlying dermis. Purified kalinin localizes to the anchoring filaments of basement membranes or human subepithelial skin, trachea, esophagus, cornea a... | 10/04/1994 |
| 5312900 | 23K protein with binding specificity for queuine The invention generally relates to the discovery of a 23 kD protein, designated herein as Queb, that has specific binding affinity for the purine base Queuine. The invention particularly relates to polypeptides having specific binding reactivity with Queu... | 05/17/1994 |
| 5290915 | Placenta-derived coagulation inhibitor A monoclonal antibody specific to a human placenta-derived coagulation inhibitor is disclosed. The antibody is produced by culturing a hybridoma which secretes it. A human placenta-derived coagulation inhibitor can be purified by using the monoclonal anti... | 03/01/1994 |
| 5264550 | Human anti-inflammatory phospholipase inhibitor protein Cloning and expression of the gene encoding human phosphlipase inhibitory protein (hPIP) permits production of an anti-inflammatory protein in practical quantities using recombinant techniques.... | 11/23/1993 |
| 5210185 | Human nerve growth factor The present invention is directed to a method for the isolation of Human Nerve Growth Factor (HNGF) from human placenta. More particularly, the invention is directed to the method of isolation of the ଲ-subunit of Human Nerve Growth Factor and Compos... | 05/11/1993 |
| 5202419 | Anticoagulative protein PP4-X The protein PP4-X, whose amino acid sequence and the DNA sequence coding for this have been determined, has anticoagulative properties and can be prepared by genetic manipulation. PP4-X is used for therapeutic and diagnostic purposes.... | 04/13/1993 |
| 5179195 | Human relaxin polypeptides Genes and DNA transfer vectors for the expression of human preprorelaxin; sub-units thereof, including genes and transfer vectors for expression of human prorelaxin and the individual A, B and C peptide chains thereof; and equivalents of all such genes. M... | 01/12/1993 |
| 5175005 | Method of controlling lung tumor cell metastasis A method of controlling tumor cell metastasis comprising administering to a human a therapeutically effective amount of a ribonuclease inhibitor.... | 12/29/1992 |
| 5145962 | Human pro relaxin polypeptides Genes and DNA transfer vector for the expression of human preprorelaxin; subunits thereof, including genes and transfer vectors for expression of human prorelaxin and the individual A, B and C peptide chains thereof; and equivalents of all such genes. Met... | 09/08/1992 |
| 5140100 | Protein that inhibits production of human choriogonadotropin A substance having an inhibitory effect on the production of human choriogonadotropin (hCG) is described, which comprises a protein isolated from human decidual cells with a molecular weight of about 7,000 to about 10,000 daltons, and useful for use in in... | 08/18/1992 |
| 5053488 | Molecular cloning and characterization of a gene sequence coding for human relaxin Genes and DNA transfer vectors for the expression of human preprorelaxin; sub-units thereof, including genes and transfer vectors for expression of human prorelaxin and the individual A, B and C peptide chains thereof; and equivalents of all such genes. M... | 10/01/1991 |
| 5023321 | Molecular cloning and characterization of a further gene sequence coding for human relaxin Genes and DNA transfer vectors for the expression of human preprorelaxin; sub-units thereof, including genes and transfer vectors for expression of human prorelaxin and the individual A, B and C peptide chains thereof; and equivalents of all such genes. M... | 06/11/1991 |
| 5019556 | Inhibitors of angiogenin An inhibitor of angiogenin and method of use of the inhibitor, wherein the inhibitor inhibits the angiogenic activity of angiogenin. The inhibitor is dispensed at a suitable concentration within a physiologically compatable medium, suitable for administra... | 05/28/1991 |
| 4994559 | Human basic fibroblast growth factor An angiogenic factor is disclosed which is a purified, single-polypeptide-chain protein having at least one active site possessing an activity selected from the group consisting of mitogenic activity, chemotactic activity, the ability to stimulate proteas... | 02/19/1991 |
| 4990597 | Process for the purification of placental tissue protein PP4 A process for the purification of tissue protein PP4 which can be obtained from placenta is described. This process makes use of the property of binding to saccharide polysulfates or to sulfated sugars in the presence of calcium ions.... | 02/05/1991 |
| 4937324 | Chromatographic purification of human proteins having anticoagulant and anti-inflammatory activity Proteins having therapeutic potential as both anticoagulants and as anti-inflammatory agents are disclosed. The present invention also discloses the use of lipocortins in reducing blood coagulation in warm-blooded animals.... | 06/26/1990 |
| 4847363 | Physiologically active glycoprotein and process for production thereof A new glycoprotein ZP-0 originating from the oviduct of a mammal having a molecular weight of about 200,000 to 240,000, as determined by SDS-polyacrylamide gel density-gradient electrophoresis having an isoelectric point of about 4 to 6.2, as determined b... | 07/11/1989 |
| 4801689 | Physilogically active glycoprotein and process for production thereof A new glycoprotein ZP-0 originating from the oviduct of a mammal having a molecular weight of about 200,000 to 240,000, as determined by SDS-polyacrylamide gel density-gradient electrophoresis having an isoelectric point of about 4 to 6.2, as determined b... | 01/31/1989 |
| 4732891 | Placenta-derived anticoagulating substance, process for preparing same and anticoagulant comprising same as an effective component Novel human placenta-derived anticoagulating substances having the following properties: (1) molecular weight of 34,000&#b1;2,000 determined by SDA-polyacrylamide gel electrphoresis under reduced state; (2) isoelectric point of 4.7&#b1;0.1 determined by isoele... | 03/22/1988 |
| 4638050 | Thrombin-binding substance and process for its production A thrombin-binding substance derived from human tissue and having the characteristics of (a) molecular weight: 88,000&#b1;20,000 in reduced condition and 71,000&#b1;20,000 in unreduced condition; (b) isoelectric point: p H 4.2&#b1;0.5; (c) affi... | 01/20/1987 |
| 4597899 | Process for obtaining a factor XIII preparation, and its use A process for obtaining a factor XIII preparation is described, in which the factor XIII is precipitated from a placental extract using an alcohol, and is adsorbed onto an anion exchanger, and the exchanger is washed and the factor XIII is eluted. The fac... | 07/01/1986 |
| 4592863 | Protein PP20, a process for obtaining it, and its use The protein PP20 is described, this having the following characteristics: (a) an electrophoretic mobility which is somewhat larger than that of albumin, (b) an isoelectric point of 4.65&#b1;0.1, (c) a sedimentation coefficient s20,w of 4.... | 06/03/1986 |
| 4558035 | Material for use in the treatment of spontaneous abortions This invention relates to a material for use in preventing recurrent spontaneous abortions in women, comprising material selected from isolated syncytiotrophoblast microvillous plasma membrane and protein- and glycoprotein-containing fractions derived the... | 12/10/1985 |
| 4541953 | Preparation of anti-T-lymphocyte globulin Anti-T-lymphocyte globulin is prepared from the serum of immunized animals. Cells of the cell line JM are used for immunization. Anti-T-lymphocyte globulin is prepared by means of hybrid cells, which are obtained by a hybridization of myeloma cells capabl... | 09/17/1985 |
| 4524027 | Membrane-associated proteins (MP2), a process for obtaining them, and their use Membrane-associated proteins, called MP2, and a process for obtaining them are described. The proteins have the following parameters: (a) an electrophoretic mobility in the range between that of 댒 and that of 댡 gl... | 06/18/1985 |
| 4511653 | Process for the industrial preparation of collagenous materials from human placental tissues, human collagenous materials obtained and their application as biomaterials This process of preparation consists in subjecting said placental tissue after pressing, grinding and washing in a neutral and acid medium to a treatment in alkaline medium at a temperature less than or equal to 10° C. and in then subjecting the portions... | 04/16/1985 |
| 4507277 | Composition and method for stimulating the synthesis of the melanotic pigment of the skin A composition useful in the treatment of vitiligo, a method for preparing said composition and a method of treating vitiligo with said composition wherein said composition comprises a placental alpha lipoprotein component extracted from placental cotyledo... | 03/26/1985 |
