"We live in a society exquisitely dependent on science and technology, in which hardly anyone knows anything about science and technology."
|6929924||C-peptide specific assay procedure|
The present invention relates to a specific C-peptide assay method which can eliminate all interference due to proinsulin and its intermediates, in particular des-31,32-proinsulin and/or des-64,65-proinsulin. It also relates to antibodies for carrying out this assay...
|6391651||Materials and methods for detection of insulin dependent diabetes|
The method and compositions of this invention provide an effective and reliable substitute for the currently employed ICA assay for diabetes. By providing a method for detecting autoantibodies to both GAD65 and IA-2 auto-antigens, the method pr...
|5356781||Zymogen activation peptides (ZAP) in the diagnosis of disease|
Pancreatic disease can be diagnosed by assaying a patient's body fluid such as serum or urine, for pancreatic activation peptides (PAP) released from zymogens by proteolytic activation. Particularly useful are peptides having C-terminal D4 K se...
|5328986||Smooth muscle mitogen|
A novel growth factor (BTC-GF) was purified from the conditioned medium of pancreatic beta tumor cells initially derived from transgenic mice (RIPI-Tag2). The purification scheme included BioRex 70 chromatography, phenyl-Sepharose chromatography, TSL-GEL ...
|5298605||Antibodies to islet amyloid polypeptide (IAPP) and subunits thereof|
This invention is directed to antibodies which react with human islet amyloid polypeptide and which do not significantly react with insulin or calcitonin gene-related peptides. Preparations of antibodies are provided which bind to islet amyloid polypeptid...
|5229493||Smooth muscle mitogen|
A novel growth factor (BTC-CG) was purified from the conditioned medium of pancreatic beta tumor cells initially derived from transgenic mice (RIPl-Tag2). The purification scheme included BioRex 70 chromatography, phenyl-Sepharose chromatography, TSL-GEL ...
|5122594||Modified human pancreatic secretory trypsin inhibitor|
DNA sequences encoding modified varieties of human PSTI possessing excellent stability in terms of decreased susceptibility to decomposition by proteolytic enzymes such as trypsin, as compared with natural human PSTI, as well as the modified varieties of ...
|5112945||Preparation of islet amyloid polypeptides (IAPP) and antibodies to IAPP|
Subunits of the full length 37 amino acid residue human Islet Amyloid Polypeptide, and feline Islet Amyloid Polypeptide essentially free of unpolymerized amyloid are provided. Islet Amyloid Polypeptide (IAPP) may be isolated and purified from amyloid fibr...
|4952507||Production and diagnostic use of antibodies against pancreatic alpha-amaylase|
Antibodies specific for pancreatic alpha-amylase and methods for their production are described. These antibodies may be used for the detection and quantification of pancreatic alpha-amylase in biological fluids, tissue extracts, or extracts of stains of ...
|4563352||Human pancreatic GRF|
Human pancreatic GRF has been synthesized. The invention provides synthetic peptides which are extremely potent in stimulating the release of pituitary GH in mammals and which have the formula: H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-R
|4446240||Pancreas specific protein systems|
Pancreas specific protein systems, including Pan Ag purified antigen having molecular mass of about 2.25×105 daltons and pancreas specific antibodies to such antigen, and methods for providing and utilizing such antigen and antibodies....
|4438104||Endorphins having placental or pancreatic origin|
An endorphin peptide is described that has a molecular weight by amino acid analysis of about 14,000 daltons, an infrared spectrum substantially as shown in FIG. 5, and an amino acid analysis substantially as follows: The peptide is immunoreactive against ...
|4316895||Endorphins having placental or pancreatic origin|
A peptide endorphin having a molecular weight in the range of about 4500 to 5000 daltons is described. This peptide endorphin has ଲ-endorphin-like activity, reacting immunologically to rabbit antisera prepared against ଲ-endorphin and displacin...
|4029641||Process for the simultaneous obtention of insulin and pancreatin from swine pancreases|
A process for the simultaneous obtention of insulin and pancreatin from fresh or deep frozen swine pancreases by extracting the glands at a pH of about 5 to 7 with a reaction mixture containing at least 40% of acetone, separating the extracted substance a...