Did You Know...
...that two musicians were responsible for the invention of color print film? Fascinated by photography, Leopold Godowsky and Leopold Mannes worked together to produce an easy-to-use, practical color film. They worked full time as music teachers and gave concerts while experimenting during their off hours in Mannes' kitchen. Their success earned them full-time, well-paying jobs at Kodak and their efforts resulted in Kodachrome film, which was introduced in 1935.
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| Number | Title | Issue Date |
| 7153519 | Implantable substrate coated with a macromer having free radical polymerizable substituents Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The... | 12/26/2006 |
| 6872576 | Antigens embedded in thermoplastic The invention relates to an immunoassays, binding assays, solid phase substrates (12) and other devices with an antigen or antibody or ligand or receptor (11) embedded into a solid phase substrate (12). The antigen or antibody is mixed with a mo... | 03/29/2005 |
| 6685957 | Preparation of fibrous polymer implant containing bioactive agents using wet spinning technique A fibrous polymer implant loaded with one or more bioactive agents is prepared using a wet spinning technique. Preferably, an aqueous solution of bioactive agent is added to a solution of amphiphilic block copolymer containing hydrophilic blocks such as p... | 02/03/2004 |
| 6680184 | Encapsulating liquid with hydrocolloid membrane stable from about -20 to 90 degrees C without bursting A temperature-stable droplet is provided containing a temperature-stable hydrocolloid membrane. The hydrocolloid membrane encapsulates a liquid that contains at least one enzyme, a cell, a biological agent, a pharmaceutical agent, an immunological agent, ... | 01/20/2004 |
| 6632446 | Coating substrates by polymerizing macromers having free radical-polymerizable substituents Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active mat... | 10/14/2003 |
| 6616946 | Triblock copolymer hollow particles for agent delivery by permeability change Polymeric hollow particles for delivery of an agent are provided that change permeability in response to a change in an external stimulus such as pH, temperature, light, ionic strength, electric field, magnetic field and/or solvent composition. The partic... | 09/09/2003 |
| 6465001 | Treating medical conditions by polymerizing macromers to form polymeric materials Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active mat... | 10/15/2002 |
| 6444261 | Storage-stable particle, in particular carrier for carrier-bound reactions, and methods of producing said particle A particle resistant to storage of at least one first and at least one second component, wherein said second component of at least one crosslinkable polymer as a shell at least partially envelops and/or encloses said first component as a core and said fir... | 09/03/2002 |
| 6399750 | IGG separation medium A separation medium having a base matrix and matrix-bound groups which exhibit recombinant Protein A containing a cysteine. The groups are of formula: --B--X--rProtein A-cys where B is a bridge which binds to the base matrix and X includes a heteroatom N ... | 06/04/2002 |
| 6384188 | Lipopolysaccharide-binding and neutralizing peptides Substance which bind with high affinity to endotoxin (lipopolysaccharide [LPS]), and which are useful for the prevention or treatment of, for example, Gram-negative and Gram-positive bacterial sepsis, and for the treatment of bacterial and fungal infectio... | 05/07/2002 |
| 6312942 | Apparatus for encapsulating substances in small spherical particles formed from an encapsulating fluid Substances such as chemical substances and biological substances including animal, vegetable and microbial cells are encapsulated using a process and an apparatus wherein a coil through which alternating current flows causes a magnet to vibrate creating v... | 11/06/2001 |
| 6306959 | Rapid purification by polymer supported quench Novel polymer-supported quenching reagents of Formula (I): P-L-Q, wherein P is a polymer of low chemical reactivity which is soluble or insoluble; Q is one or more quenching reagents, or an acid or base addition salts thereof, that are capable of selectiv... | 10/23/2001 |
| 6291582 | Polymer-protein composites and methods for their preparation and use A method of preparing a polymer-protein composite based upon placing a protein in solution in an organic phase via the ion-pairing of the protein with a surfactant. The polymer-protein composites are useful, for example, as highly active and stable cataly... | 09/18/2001 |
| 6287558 | Devices containing cells or tissue and an agent that inhibits damage by a host cell molecule A device that includes a living cell or tissue and an agent that inhibits the ability of a host molecule to damage the cell or tissue. The device can be constructed in various forms including an implantable device, a composite microreactor and a double co... | 09/11/2001 |
| 6204256 | Acylated cyclodextrin derivatives A cyclodextrin derivative, wherein at least 60 percent of the free hydroxy groups of said cyclodextrin are acylated with acyl groups where at least one of said acyl groups comprise a free carboxylic group.... | 03/20/2001 |
| 6150472 | Multi-functional site containing polymers, and applications thereof Polymers having multi-functional sites and a gel comprising a solvent swollen network of cross-linked polymer(s), of which at least one polymer comprises at least one multi-functional site. A multi-functional site is a sequence of more than one functional... | 11/21/2000 |
| 6096825 | Electrically conductive electroactive functionalized conjugated polymers, and uses thereof There are electrically conductive, electroactive functionalized conjugated polymers having formula (I): ##STR1## These electrically conducive, electroactive conjugated polymers may be covalently bonded to a first biological molecule or antiligand. Po... | 08/01/2000 |
| 6066331 | Method for preparation of vesicles loaded with biological structures, biopolymers and/or oligomers A composition useful for preparing vesicles loaded with biological cell-structures, biopolymers and/or -oligomers is prepared by solubilizing amphiphatic material such as a phospholipid in a polar-protic solvent miscible with water, solubilizing biologica... | 05/23/2000 |
| 6020175 | Multiple layered functional thin films Multiple layered functional thin films fixed on a solid support are provided which comprise multiple layers of functional molecules (such as enzymes and other proteins, pigments and dyes) admixed with polymer ions in combination with multiple layers of po... | 02/01/2000 |
| 5969040 | Factor IX -- polymeric conjugates Conjugates containing a substance with coagulant activity, such as recombinant Factor IX, non-antigenic polymers, such as poly(ethylene glycol), are disclosed. Also disclosed are methods of forming the novel conjugates of this invention.... | 10/19/1999 |
| 5968729 | Use of centrifugation to prepare a retractable seal over reagents in a reaction container A method is provided using centrifugation to prepare a seal of solidified wax, grease or polymer mix over an aqueous reagent in a reaction container such that the reagent is separated from contact with the atmosphere. The amount of solidified wax, grease ... | 10/19/1999 |
| 5965454 | Automated histo-cytochemistry apparatus and encapsulation system for processing biological materials There is disclosed an automated apparatus, reagents and process for immunocytochemical staining of biological materials using ligand pairing. The present invention provides a method for storing a ligand in a macroscopic solid support and releasing the lig... | 10/12/1999 |
| 5948889 | Compositions and methods for screening antimicrobials A method for screening compounds for antimicrobial activity is described that utilizes bacterial protein-protein binding in vitro. The method may be performed using immobilized elements and the immobilization may be carried out using a variety of immobili... | 09/07/1999 |
| 5902799 | Methods of modulating tissue growth and regeneration Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a heparin binding growth factor. These compositions are of low sol... | 05/11/1999 |
| 5807757 | Preparation of ionically cross-linked polyphosphazene microspheresy by coacervation A method is provided for preparing polyphosphazene microspheres wherein the polyphosphazene microspheres are produced by coacervation. A solution containing a polyphosphazene is admixed with a solution containing a salt of a monovalent ion such as a salt ... | 09/15/1998 |
| 5723588 | Protein-enriched thermoplastics Thermoplastics interdispersed with a variety of functional thermostable polypeptides, including proteins, and methods of making such thermoplastics are provided. The disclosure demonstrates that certain polypeptides can retain functional activity through ... | 03/03/1998 |
| 5700783 | Method of treating urinary incontinence A method for treating urinary incontinence consisting of injecting human fibrin glue at or near the bladder neck until the urethral outflow resistance is restored. Human fibrin glue is the reaction product of human fibrinogen and thrombin in the presence ... | 12/23/1997 |
| 5656450 | Activation of latent transforming growth factor ଲ by matrix vesicles A latent growth factor such as transforming growth factor beta (TGFଲ) is converted to active form by matrix vesicles or an extract from matrix vesicles. The matrix vesicles may be stimulated with a Regulator of Enhancing Factor (REF) such as 1,25-di... | 08/12/1997 |
| 5650489 | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof The instant invention provides a library of bio-oligomers of defined size and known composition, in which the library contains all of the possible sequences of the bio-oligomers, and a method of synthesis thereof. The bio-oligomers of the library may be p... | 07/22/1997 |
| 5643773 | Preparation of elongated seamless capsules containing a coaxial rod and biological material Elongated seamless capsules containing biological material are prepared by a method in which a coagulant, which includes a cell suspension or other biological material, and a polymeric casting solution are extruded through a common extrusion port having a... | 07/01/1997 |
| 5643764 | Reactions using heat-releasable reagents in wax beads A reagent such as a heat resistant enzyme is entrapped in a material such as wax or a liposome that releases the reagent when heated so the reagent is available for reaction. In a preferred embodiment, wax beads containing the reagent are prepared by inje... | 07/01/1997 |
| 5563056 | Preparation of crosslinked matrices containing covalently immobilized chemical species and unbound releasable chemical species A chemical specie is immobilized in a three dimensional, crosslinked matrix by bringing together in covalent bonding proximity a desired chemical specie and a polymeric coupling compound such as a photoderivatized polymer having at least two latent photoc... | 10/08/1996 |
| 5550044 | Preparation of wax beads containing a reagent using liquid nitrogen for cooling and solidifying Droplets of molten wax or waxy polymer containing a reagent are dropped onto the surface of liquid nitrogen, the droplets remain on the surface until solidified and the droplets are removed from the surface before they sink into the liquid nitrogen to pro... | 08/27/1996 |
| 5418154 | Method of preparing elongated seamless capsules containing biological material Elongated seamless capsules containing biological material are prepared by a method in which a coagulant, which includes a cell suspension or other biologically active factor, and a polymeric casting solution are extruded through a common extrusion port h... | 05/23/1995 |
| 5413924 | Preparation of wax beads containing a reagent for release by heating A reagent such as an enzyme is entrapped in a material such as wax or a liposome that releases the reagent when heated. In a preferred embodiment, wax beads containing the reagent are prepared by injecting the reagent into beads of molten wax and cooling ... | 05/09/1995 |
| 5310885 | Process for immobilizing a protein containing substance on a solid phase The present invention provides a process for immobilizing a protein or protein containing substance. The material to be immobilized is aggregated, contacted in a liquid with a hydrophilic solid phase and the solid phase, after contact has taken place, is ... | 05/10/1994 |
| 5283186 | Preparation of a compressed membrane containing immobilized biologically acting material A porous carrier containing an immobilized biologically active material is prepared in which a relatively large amount of an enzyme or an antibody has been immobilized in a manner that produces a low diffusion resistance toward reagents and products. The ... | 02/01/1994 |
| 5223435 | Amino acid sequence determination with mobile peptide Sequential degradation of peptides for sequencing purposes by successive cleavage of amino acids from one end of the peptide chain is performed in an adsorption column with flows of the degradation reagents and wash liquids passing through the column in b... | 06/29/1993 |
| 5104931 | Process for the production of immobilized antibodies A single-step procedure for the immobilization of antibodies, comprising reacting a purified antibody with buffered periodate in an amount sufficient to produce aldehyde groups in the presence of a polymer carrier material which has been modified with adi... | 04/14/1992 |
| 5089407 | Encapsulation of biological material in non-ionic polymer beads Biological materials such as enzymes, proteins and peptides are encapsulated by forming a mixture of the material and an aqueous non-ionic polymer solution, spraying the mixture into a circulating water-immiscible nonsolvent for the polymer at a temperatu... | 02/18/1992 |
