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Class 530/422 - Solvent extraction


Subclass of Class 530 - Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Definition: Process in which a protein is separated from a solid or
No. of patents: 202
Last issue date: 03/27/2012


1            
NumberTitleIssue Date
8143381Use of ionic liquids for membrane protein extraction
The present invention relates to the use of ionic liquids or of mixtures comprising at least one ionic liquid and at least one further solvent for the extraction of membrane proteins from biological samples, to methods for the extraction of membrane proteins, to a k...
03/27/2012
7365173Method for the production of pure virally inactivated butyrylcholinesterase
The present invention provides a method for purifying butyrylcholinesterase from various biological fluids. Biological fluids include, e.g., blood, blood fractions, plasma, and bioreactor broths, and other such mixtures containing butyrylcholinesterase. In one embod...
04/29/2008
7358342Preparation derived from shark cartilage for treatment of diseased related to excessive PHF or excessive intracellular calcium
A preparation derived from shark cartilage for the treatment of diseases related to excessive PHF or Excessive intracellular calcium. ...
04/15/2008
7335739Methods for the purification and aqueous fiber spinning of spider silks and other structural proteins
Methods are described for the purification and spinning of recombinant and non-recombinant proteins. Specifically, the lysis of bacteria and purification of silk proteins occur in a single solution of organic acid. Bacterial proteins are hydrolyzed while the silk pr...
02/26/2008
7229789Methods and compositions for extracting proteins from cells
A process is disclosed for releasing proteins from cells and/or inactivating viruses. In the process, a host cell containing a protein of interest is contacted with a solution of an effective amount of a detergent. ...
06/12/2007
7193056Process for purifying a compound
The present invention relates to a process for purifying a hydrophobic or amphiphilic compound, by first mixing a starting material containing the hydrophobic or amphiphilic compound with a first polymeric material, water and at least one of a second polymeric mater...
03/20/2007
7134954Method for producing modified natural intestines
The present invention is to provide a method for producing an animal natural intestine having improved texture and hardness by treatment with a solution containing a food emulsifier. ...
11/14/2006
7098026Human desert hedgehog protein
Disclosed are a novel hedgehog protein, i.e., a Desert hedgehog protein of human origin including mature and precursor forms, a DNA encoding the protein, a monoclonal antibody recognizing the protein, a process for producing the protein, and a method for detecting t...
08/29/2006
7067639Method to provide bacterial ghosts provided with antigens
Methods for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium are disclosed. The proteinaceous substance includes an AcmA cell-wall binding domain, homolog or functional derivative thereof. The method includes treating...
06/27/2006
7048930Expression of core-glycosylated HCV envelope proteins in yeast
The present invention relates to the general field of recombinant protein expression, purification of recombinant proteins, diagnosis of HCV infection, prophylactic treatment against HCV infection and to the prognosing/monitoring of the clinical efficiency of treatm...
05/23/2006
7029707Method of producing a processed kava product having an altered kavalactone distribution and processed kava products produced using the same
A method of producing a processed kava product involves using an extraction solvent, such as liquid CO2, to preferentially extract different kavalactones from the source material at different rates. By controlling the extraction parameters and stopping th...
04/18/2006
7019120Cloud-point extraction of enzymes and polypeptides from a fermentation broth using a non-ionic surfactant
A method of extracting a polypeptide of interest from a fermentation broth comprising: i) adjusting the pH close to pI of the polypeptide of interest; ii) adding a non-ionic surfactant with a hydrophile-lipophile b...
03/28/2006
6994847Stabilized interferon compositions
Stabilized pharmaceutical formulations comprising IFN-β and highly purified mannitol are provided. The highly purified mannitol stabilizes the compositions by reducing the formation of IFN-β adducts in comparison with IFN-β formulated with mannitol that has not b...
02/07/2006
6967239Method of filtering viruses from a factor VIII solution
Method for preparing a factor VIII solution that is essentially free of viruses and essentially devoid of vWF (von Willebrand factor) and factor VIII-vWF complexes by (a) obtaining a starting factor VIII solution devoid of factor VIII-vWF complexes; and (b) filterin...
11/22/2005
6967241Process for protein extraction
The invention includes a process for extracting a target protein from E. coli cells that includes lowering the pH of a whole E. coli cell solution to form an acidic solution, disrupting the cells to release the protein into the acidic solution, and sep...
11/22/2005
6924267Methods and active substances for protecting organs
The present invention comprises a method of protecting organs or tissue susceptible to reperfusion-induced dysfunction after ischemia. The method comprises parenterally administering to a patient a therapeutical composition containing natural alpha-1 acid glycoprote...
08/02/2005
6916914Purification of somatotropin from transformed microorganisms
This invention discloses a commercially advantageous process for extraction and purification of protein from microorganisms. The initial steps of the process are useful for purifying many insoluble proteins while later steps are designed to renature denatured somato...
07/12/2005
6894023Growth hormone crystals and a process for production of these GH-crystals
A process for producing cation crystals of growth hormone or growth hormone derivatives, as well as growth hormone and growth hormone derivatives. The process of producing the growth hormone crystals includes the steps of (a) adding cations of inorganic or organic n...
05/17/2005
6894029Use of jellyfish collagen (type II) in the treatment of rheumatoid arthritis
Compositions of substantially homogeneous type II-like collagen from invertebrates belonging to the class Scyphozoa, phylum Coelenterata, i.e., jellyfish, particularly Stomolophus meleagris, and methods for its extraction are provided. Methods for the treatme...
05/17/2005
6861505Method for recovering soluble protein
The present invention relates in providing a process for recovering a soluble protein having a higher recovery rate by suppressing the aggregation of the protein when a denaturing agent is removed from the solubilization treatment solution containing a solubilized p...
03/01/2005
6852833Artificial chaperon kit
The present invention provides an artificial chaperon useful for refolding the proteins having low voluntary folding ability and being difficult or unable to be a native form without a second (or assistant) of a molecular chaperon in a short time, and folding said p...
02/08/2005
6844321Crystallization of a GLP-1 analogue
Crystals of glucagon-like peptide-1 (GLP-1) and GLP-1 analogues, and processes for preparation of crystals of GLP-1 and GLP-1 analogues. ...
01/18/2005
6844424Method for obtaining avian biological products
This invention provides a method for separating and extracting biological products of avian origin. The method allows for the production of avian cartilages and of active ingredients which can be extracted from the cartilages thus obtained. ...
01/18/2005
6844427Method for removing the transforming growth factor-β by adsorption
An adsorbent suitable for adsorption of a transforming growth factor-β (TGF-β) comprising a compound which has a log P value of at least 2.50 wherein P is a partition coefficient in an octanol-water system and which is immobilized on a water-insoluble carrier. TGF...
01/18/2005
6821752Methods and compositions for extracting proteins from cells
The present invention relates to a process of releasing a protein, recombinant or otherwise, from a cell. The process of the present invention involves contacting a host cell containing a protein of interest with a solution comprising one or more detergents and one ...
11/23/2004
6803454Method for extraction and purification of cartilage type proteoglycan
The present invention relates to a new method for extraction and purification of cartilage type proteoglycan, and is to provide a method for extraction of crude proteoglycan characterizing to use acid as eluting solvent of cartilage. ...
10/12/2004
6767994Process for purifying a compound
The present invention relates to a process for purifying a hydrophobic or amphiphilic compound, by first mixing a starting material containing the hydrophobic or amphiphilic compound with a first polymeric material, water and at least one of a second polymeric mater...
07/27/2004
6756482Purified human activin and process for producing the same
The present invention provides a process for purifying human activin by cation exchange chromatography and chaotropic ion concentration gradient elution. ...
06/29/2004
6756041Process for preparing conjugate vaccines including free protein and the conjugate vaccines, immunogens, and immunogenic reagents produced by this process
A process for preparing a protein-polysaccharide conjugate includes reacting a protein with a polysaccharide to produce a mixture including a protein-polysaccharide conjugate and free protein. At least one unreacted reagent or low molecular weight component is remov...
06/29/2004
6756484IGF-I purification process
Disclosed is an improved process for obtaining purified, monomeric, intact, correctly-folded insulin-like growth factor-I (also known as somatomedin-C). The improvements, consisting primarily of the addition of an IGF-I unfolding/refolding step and the substitution ...
06/29/2004
6686456Method for the elimination of Kunitz and Bowman-Birk trypsin inhibitors and carboxypeptidase inhibitor from potato proteins
A method for removing protein impurities from extracts of protease inhibitor-containing plant material. Plant materials containing protease inhibitors, such a potato tubers that contain protease inhibitor II, are extracted using an alcohol-free solvent. T...
02/03/2004
6686455Tumor necrosis factor
A cytotoxic protein designated tumor necrosis factor is identified in nature. It is recovered in substantially homogeneous form by treatment with hydrophobic substances and ion exchange resins. The protein is conclusively identified by its amino acid sequ...
02/03/2004
6649740Hydratable form of keratin for use as a soil amendment
A hydratable oxidized keratin composition comprising one or more metal ion species capable of absorbing water to form a hydrogel. The keratin material is useful as a soil amendment providing organic and inorganic nutrients. The keratin material is also us...
11/18/2003
6638749Carbon dioxide soluble surfactant having two fluoroether CO2-philic tail groups and a head group
There is provided a process for the extraction of water soluble biomaterials such as enzymes or proteins into carbon dioxide utilizing certain carbon dioxide-soluble surfactants. Also provided are certain carbon dioxide-soluble surfactants useful in the e...
10/28/2003
6635746Chlamydial vaccines and immunogenic compositions containing an outer membrane antigen and methods of preparation thereof
Immunogenic compositions including vaccines are described that comprise an outer membrane antigen extract of a strain of Chlamydia and are effective in protection against disease caused by Chlamydia infection The immunogenic compositions may comprise the ...
10/21/2003
6635285Shark cartilage extract: process of making, methods of using, and compositions thereof
The present invention relates to cartilage extracts and to a method of producing the same. Shark cartilage extracts having anti-angiogenic, anti-tumor, anti-inflammatory and anti-collagenolytic activities have been obtained by an improved process. The pro...
10/21/2003
6620917Method for the purification and aqueous fiber spinning of spider silks and other structural proteins
Methods are described for the purification and spinning of recombinant and non-recombinant proteins. Specifically, the lysis of bacteria and purification of silk proteins occur in a single solution of organic acid. Bacterial proteins are hydrolyzed while ...
09/16/2003
6610831Methods and apparatus for recovering zein from corn
Methods and apparatus for recovering zein from substrates are disclosed. The method includes extracting a zein-containing substrate such as whole corn with ethanol to yield a crude zein alcoholic dispersion and treating this dispersion with an adsorbent t...
08/26/2003
6602985Extraction of zein protein from gluten meal
Zein is recovered from gluten meal prepared by wet milling procedures by washing the gluten with clean water to remove water-soluble components; separating the water-soluble components and recovering the water-insoluble components; extracting the water in...
08/05/2003
6566329Freeze-dried preparation of human growth hormone
A readily-soluble freeze-dried solid preparation of hGH with a minimal content of degradation products in terms of deamidation, dimers, polymers, and sulphoxide forms, obtainable by a method comprising a single lyophilization of an aqueous slurry of an am...
05/20/2003
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