Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8071554 | Tissue protective peptides and uses thereof The present invention is directed to novel tissue protective peptides. The tissue protective peptides of the invention may bind to a tissue protective receptor complex. In particular, the present invention is drawn to tissue protective peptides derived from or shari... | 12/06/2011 |
| 7858581 | PMMA binding peptides and methods of use Combinatorially generated peptides are provided that have binding affinity for polymethylmethacrylate (PMMA). The peptides may be used to deliver benefit agents to various PMMA surfaces. ... | 12/28/2010 |
| 7442308 | Process for removing viruses in fibrinogen solutions and fibrinogen obtained by said process A process for removing viruses in fibrinogen solutions and fibrinogen obtained thereof wherein the process starts with an adjusted purified fibrinogen solution, the adjusted purified solution is frozen and then thawed at a temperature between 5 and 20° C., the undi... | 10/28/2008 |
| 7439336 | Process for the purification of IL-18 binding protein The invention relates to a process for the purification of IL-18 binding protein (IL-18BP) from a fluid using aqueous two-phase partitioning. ... | 10/21/2008 |
| 7407932 | Methods for glucagon suppression using modified exendins Methods for use of an exendin, an exendin agonist, or a modified exendin or exendin agonist having an exendin or exendin agonist linked to one or more polyethylene glycol polymers, for example, for lowering glucagon levels and/or suppressing glucagon secretion in a ... | 08/05/2008 |
| 7247239 | Method for biological treatment of water by adding macromolecular carbohydrates The invention relates to a method for biological treatment of water, wherein macromolecular carbohydrates are added to the water to be treated, optionally together with vitamins and other additives, whereby a great reduction in residues is already achieved after add... | 07/24/2007 |
| 7211650 | Purification of fibrinogen from fluids by precipitation and hydrophoic chromatography The present invention provides a method for the part purification of fibrinogen from milk, the method comprising the transfer of protease enzyme which is present in the milk, into the whey phase with the removal or partition if fibrinogen into another phase of the m... | 05/01/2007 |
| 7193056 | Process for purifying a compound The present invention relates to a process for purifying a hydrophobic or amphiphilic compound, by first mixing a starting material containing the hydrophobic or amphiphilic compound with a first polymeric material, water and at least one of a second polymeric mater... | 03/20/2007 |
| 7141262 | Method for obtaining a TGF-beta enriched protein fraction in activated form, protein fraction and therapeutic applications The invention concerns a method for obtaining a highly enriched TGF-beta protein fraction in activated form, from a liquid solution rich in proteins said to be soluble in the aqueous phase of milk and/or of whey, said method comprising the following steps; a) adjust... | 11/28/2006 |
| 7101376 | Interlocking IM Nails with threaded guidewire A new method for locking Intramedullary Nails (IM Nails) with Threaded Guidewire. The present invention is practiced in conjunction with specifically designed tapered screws with segmented threads. This new design uses the screws to begin locking the IM Nail, follow... | 09/05/2006 |
| 7087719 | Method for the crystallization of human serum albumin The present invention relates to the purification and production of human albumin from various sources through crystallization and repeated crystallization. Basic features of the invented process include providing specific reaction conditions and precipitating reage... | 08/08/2006 |
| 7060299 | Biodegradable microparticles that stabilize and control the release of proteins Disclosed herein are biodegradable microparticle compositions, and methods for the generation of biodegradable and biocompatible microparticles that stabilize proteins and also control the kinetics of release of proteins over a period of several weeks to several mon... | 06/13/2006 |
| 7038016 | Methods for purification of an activated PEG solution and for the synthesis of a modified hemoglobin solution The present invention employs a dissolved activated polyethylene glycol (aPEG) or related molecule that has been passed through a filtration means for the substantial reduction of bioburden or endotoxin levels in the aPEG solution. The resulting filtered aPEG soluti... | 05/02/2006 |
| 7022673 | Method for increasing the serum half-life of a biologically active molecule A method is provided for preparing a biologically active molecule having an increased serum half-life. The method involves conjugating a polymer such as polyethylene glycol to the biologically active molecule. Also provided are polypeptide drugs having an increased ... | 04/04/2006 |
| 6989436 | Stabilization of cardiac troponin I subunits and complexes The present invention provides methods for preparing, and compositions comprising, stabilized protein-polymer conjugates. More particularly, the present invention relates to the stabilization of individual and complexed subunits of multisubunit protein complexes by ... | 01/24/2006 |
| 6989373 | Method for restoring a fat-pad The present invention relates to a method for treating damaged or degenerated fat pads in a foot of a host in need thereof. The method comprises the step of injecting into the fat pad of the host a biocompatiable solution having physico-chemical and mechanical prope... | 01/24/2006 |
| 6884780 | Method for increasing the serum half-life of a biologically active molecule A method is provided for preparing a biologically active molecule having an increased serum half-life. The method involves conjugating a polymer such as polyethylene glycol to the biologically active molecule. Also provided are polypeptide drugs having an increased ... | 04/26/2005 |
| 6875848 | Process for the production of virus-inactivated human gammaglobulin G The gammaglobulin is extracted from a fraction isolated by fractionation with ethanol in the presence of a carbohydrate, and after reducing the content of contaminants with PEG, it is applied to an anionic resin exchange column, an effluent being obtained in which t... | 04/05/2005 |
| 6872700 | Methods for glucagon suppression Methods for use of an exendin, an exendin agonist, or a modified exendin or exendin agonist having an exendin or exendin agonist linked to one or more polyethylene glycol polymers, for example, for lowering glucagon levels and/or suppressing glucagon secretion in a ... | 03/29/2005 |
| 6767994 | Process for purifying a compound The present invention relates to a process for purifying a hydrophobic or amphiphilic compound, by first mixing a starting material containing the hydrophobic or amphiphilic compound with a first polymeric material, water and at least one of a second polymeric mater... | 07/27/2004 |
| 6709655 | Pharmaceutical composition of F(ab1)2 antibody fragments and a process for the preparation thereof The present invention is directed to a pharmaceutical composition comprising F(ab′)2 antibody fragments that are preferably free from albumin and of whole antibodies and also substantially free of pyrogens, and an effective amount of a pharmaceutically ... | 03/23/2004 |
| 6676840 | Fat and protein removal from process streams The precipitation and removal of suspended fat and protein components and other suspended solids from a given solution can be accomplished by the addition of an aluminate to complex with the fat and protein components and the addition of a flocculating ag... | 01/13/2004 |
| 6635746 | Chlamydial vaccines and immunogenic compositions containing an outer membrane antigen and methods of preparation thereof Immunogenic compositions including vaccines are described that comprise an outer membrane antigen extract of a strain of Chlamydia and are effective in protection against disease caused by Chlamydia infection The immunogenic compositions may comprise the ... | 10/21/2003 |
| 6605273 | Renal cell carcinoma treatment Methods for treating treatment-naive as well as treatment-experienced patients having RCC to achieve at least a partial tumor response involving administering a therapeutically effective amount of pegylated interferon-alpha, e.g., pegylated interferon alp... | 08/12/2003 |
| 6559284 | Process for purifying a protein The present invention relates to a composition for use in purification of apolipoprotein A (ApoA) or apolipoprotein E (ApoE), said composition comprising a first and a second polymeric material, wherein the first and second polymeric material are immiscib... | 05/06/2003 |
| 6491923 | Stabilized conjugates of uncomplexed subunits of multimeric proteins The present invention provides methods for preparing, and compositions comprising, stabilized protein-polymer conjugates. More particularly, the present invention relates to the stabilization of individual subunits of multisubunit protein complexes by con... | 12/10/2002 |
| 6485725 | Room temperature storable immunoglobulin preparation for intravenous injection A method for producing an immunoglobulin preparation for intravenous injection, which comprises the steps of: fractionating an immunoglobulin-containing solution with 4 to 10 w/v% of polyethylene glycol having a molecular weight of from 1,000 to 10,000, a... | 11/26/2002 |
| 6479300 | Metal loaded ligand bound membranes for metal ion affinity chromatography Methods, compositions and devices for purifying polypeptides and/or proteins using metal loaded ligand bound membranes by metal ion affinity chromatography are described.... | 11/12/2002 |
| 6444211 | Purification of a pertussis outer membrane protein Pertactin (formerly 69 kDa protein) is recovered in stable biologically pure form having no detectable adenylate cyclase activity from fermentation broth from the fermentation of Bordetella pertussis as well as from the cells. The broth is processed to se... | 09/03/2002 |
| 6437101 | Methods for protein purification using aqueous two-phase extraction Methods are provided in this invention for the isolation of human growth hormone, growth hormone antagonist, or a homologue of either, from a biological source. The methods of the invention use multi-phase extraction.... | 08/20/2002 |
| 6423685 | Method for increasing the serum half-life of a biologically active molecule A method is provided for preparing a biologically active molecule having an increased serum half-life. The method involves conjugating a polymer such as polyethylene glycol to the biologically active molecule. Also provided are polypeptide drugs having an... | 07/23/2002 |
| 6372145 | Fat and protein removal from process streams The precipitation and removal of suspended fat and protein components and other suspended solids from a given solution can be accomplished by the addition of an aluminate to complex with the fat and protein components and the addition of a flocculating ag... | 04/16/2002 |
| 6350730 | OB polypeptides and modified forms as modulators of body weight The present invention relates generally to the control of body weight of animals including mammals and humans, and more particularly to materials identified herein as modulators of body weight, and to diagnostic and therapeutic uses of such modulators. In... | 02/26/2002 |
| 6307013 | Clarification of protein precipitate suspensions using anionic polymeric flocculants Protein suspensions comprising soluble and insoluble components are purified via flocculation with anionic polymers, such as polyacrylamides, potato starch, or modified cellulose. The procedure improves the efficiency of solid/liquid separations and can m... | 10/23/2001 |
| 6284874 | Process for separating 댑-proteinase inhibitor from cohn fraction IV1 and IV4 paste The present invention is directed to a process for purifying 댑 -proteinase inhibitor. The process comprises providing an impure protein fraction which comprises 댑 -proteinase inhibitor. The impure protein fraction is pr... | 09/04/2001 |
| 6281336 | Process for producing immunoglobulins for intravenous administration and other immunoglobulin products The present invention relates to a process for purifying immunoglobulin G from a crude immunoglobulin-containing plasma protein fraction. Said process includes a number of steps of which the anion exchange chromatography and the cation exchange chromatogr... | 08/28/2001 |
| 6261803 | Process for preparing functional recombinant tissue factor The present invention relates to a process for preparing functional recombinant tissue factor in a prokaryotic host organism.... | 07/17/2001 |
| 6204362 | Method of purifying whey of lactic acid fermentation by electrodialysis In a method of purifying whey separated from lactic acid fermentation liquid by electrodialysis wherein said whey contains angiotensin-converting enzyme inhibiting peptides, the improvement which comprises using an anion exchange membrane having a permeab... | 03/20/2001 |
| 6166187 | Method of concentrating prion proteins in blood samples A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected to separation processing (e.g. centrifugation) to obtain ... | 12/26/2000 |
| 6159471 | Room temperature storable immunoglobulin preparation for intravenous injection A method for producing an immunoglobulin preparation for intravenous injection, which comprises the steps of: fractionating an immunoglobulin-containing solution with 4 to 10 w/v % of polyethylene glycol having a molecular weight of from 1,000 to 10,000, ... | 12/12/2000 |
