Quotables
"The idea that cavalry will be replaced by these iron coaches is absurd. It is little short of treasonous."
Aide-de-camp to Field Marshal Haig ; At a tank demonstration, 1916
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8088900 | Two-phase precipitation of proteins Provided are new methods for precipitating proteins comprising (a) providing a protein solution, (b) adding a salt to the solution, (c) either (i) adjusting pH of the composition to below the pI of the protein (in cases where the method is directed towards precipita... | 01/03/2012 |
| 7579448 | Purification of microbial cell fermentation homogenates A method for purifying a desired heterologous polypeptide from microbial fermentation broth or homogenate in which it is produced and solubilized is described. This method involves adding to the broth or homogenate an effective amount of a solution of 6,9-diamino-2-... | 08/25/2009 |
| 7264932 | Nuclease inhibitor cocktail Methods and compositions for inhibiting and/or inactivating nucleases by using nuclease inhibitors are provided. The nuclease inhibitors comprise anti-nuclease antibodies and non-antibody nuclease inhibitors. ... | 09/04/2007 |
| 7262058 | Method for determining lipid associated sialoprotein in body fluids The amount of lipid associated sialoprotein (LSP) in body fluids such as cerebrospinal fluid, peritoneal fluid, pleural fluid, bronchial washings, saliva and sputum samples, may be determined by a method which may be automated, involving the following steps to be pe... | 08/28/2007 |
| 7244828 | Agent for protein precipitation, a method of protein precipitation, a method of protein assay using protein precipitation agent, and a kit for protein assay A method of protein precipitation, concentration and removal of non-protein agents from the protein solution wherein the protein solution is treated with a protein-precipitation agent containing an acidic agent, a salt and a precipitate forming agent. After precipit... | 07/17/2007 |
| 7232894 | Method for the production of recombinant peptides with a low amount of trisulfides Methods for the production of recombinant peptides comprise fermenting cells to produce recombinant peptides. A metal salt is added to a concentrate of the fermented cells after the fermentation step, prior to peptide isolation, and the pH of the cell concentrate af... | 06/19/2007 |
| 7217784 | VP1 of foot-and-mouth disease virus A pure, water-soluble polypeptide containing one or more monomers of a VP1 protein of a foot-and-mouth disease virus; or a pure, water-insoluble polypeptide comprising two or more monomers of a VP1 protein of a foot-and-mouth disease virus. Also disclosed are a vacc... | 05/15/2007 |
| 7201901 | Capture, concentration and quantitation of abnormal prion protein from biological fluids using depth filtration Methods for producing biological solutions such as immunoglobulins and in particular anti-D immunoglobulin substantially free of abnormal prion protein resulting therefrom. Specifically provided are methods for aggregation of prions and depth filtration of the biolo... | 04/10/2007 |
| 7169908 | Purification of polypeptides A method for purifying a desired heterologous polypeptide from microbial fermentation broth or homogenate in which it is produced and solubilized is described. This method involves adding to the broth or homogenate an effective amount of a solution of 6,9-diamino-2-... | 01/30/2007 |
| 7166477 | Muscle sample prepared for prion assay A method of preparing a sample of muscle tissue and of assaying the prepared sample to determine the presence of prions in the sample is disclosed. The muscle tissue is homogenized and mixed with a complexing agent which forms a complex with a higher specific gravit... | 01/23/2007 |
| 7151000 | Method of concentrating proteins from serum A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected to separation processing (e.g. centrifugation) to obtain serum. The ... | 12/19/2006 |
| 7148343 | Compositions and methods for using a solid support to purify RNA Reagents, methods and kits for the purification of RNA from biological materials are provided. ... | 12/12/2006 |
| 7138507 | Method of determining a chemotherapeutic regimen based on glutathione-s transferase pi expression The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing GST-pi expression levels in fixed or fixed and paraffin embedded tissues and prognostica... | 11/21/2006 |
| 7132238 | Method of determining a chemotherapeutic regimen based on ERCC1 expression The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing ERCC1 expression levels in fixed or fixed and paraffin embedded tissues and determine a ... | 11/07/2006 |
| 7105638 | Product and process for the production, isolation, and purification of recombinant polypeptide Disclosed is a method for the isolation and purification of polypeptides expressed in host cells by recombinant DNA techniques. A fused polypeptide is produced containing a desired polypeptide fused to additional amino acids. The additional amino acids define a lead... | 09/12/2006 |
| 7098309 | Recombinant hepatitis B surface antigen The present invention provides an improved rHBsAg that exhibits a higher antigenicity and immunogenicity than that previously known in the art. A method of making the improved rHBsAg is also provided. The improved HBsAg is used to provide vaccines with lower amounts... | 08/29/2006 |
| 7098315 | Method of preparing a collagen sponge, a device for extracting a part of a collagen foam, and an elongated collagen sponge A method of preparing a collagen sponge comprises mixing air into a collagen gel, so as to obtain a collagen foam which is dried. From the dried product thereby obtained, collagen sponge is obtained by isolating parts of sponge with a chamber diameter of more than 0... | 08/29/2006 |
| 7087719 | Method for the crystallization of human serum albumin The present invention relates to the purification and production of human albumin from various sources through crystallization and repeated crystallization. Basic features of the invented process include providing specific reaction conditions and precipitating reage... | 08/08/2006 |
| 7057016 | Process for the production of biologically active protein The present invention relates to a folding process for the preparation of biologically active, dimeric, TGF-β (Transforming Growth Factor type β)-like protein in a detergent-free folding buffer. ... | 06/06/2006 |
| 7049059 | Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing TS and/or ERCC1 expression levels in fixed or fixed and paraffin embedded tissues and pr... | 05/23/2006 |
| 7045297 | Rapid prion-detection assay Assays are provided for rapid detection, with high specificity of the pathogenic form of prion protein responsible for neurodegenerative diseases affecting humans and animals, such as transmissible spongiform encephalopathy in bovine, sheep, and cats. Also provided ... | 05/16/2006 |
| 7033495 | Self contained dissolved air flotation system A dissolved air flotation system and method for purifying fresh water. The system is self-contained within a standard shipping container, with all components disposed in-line within the shipping container. Float is removed from the flotation tank with a skimmer that... | 04/25/2006 |
| 7030091 | Non-aqueous injectable formulation preparation with pH adjusted for extended release of somatotropin The present invention provides compositions of matter which allow for the extended release and enhanced bioavailability of biologically-active polypeptides following parenteral delivery to an animal. More particularly, it concerns compositions comprising biologicall... | 04/18/2006 |
| 7022822 | Highly purified gonadotropin compositions and process for preparing them Purification process of humanPurification process of human urinary gonadotropins of high biological activity and chemical purity absolutely free of foreign contaminating materials derived from the use of biological reagents or chromatography dyes, from crude of gona... | 04/04/2006 |
| 7011752 | Wastewater separator and method of using same A wastewater separator to separate waste from a mixed wastewater stream including one or more of heavy waste, light waste and water. The wastewater separator comprises a separation container, a inlet and an outlet. The separation container comprises (1) a wastewater... | 03/14/2006 |
| 7005278 | Method of determining dihydropyrimidine dehydrogenase gene expression The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing Dihydropyrimidine dehydrogenase (DPD) expression levels in tissues and prognosticate the... | 02/28/2006 |
| 6967239 | Method of filtering viruses from a factor VIII solution Method for preparing a factor VIII solution that is essentially free of viruses and essentially devoid of vWF (von Willebrand factor) and factor VIII-vWF complexes by (a) obtaining a starting factor VIII solution devoid of factor VIII-vWF complexes; and (b) filterin... | 11/22/2005 |
| 6956111 | Method of determining dihydropyrimidine dehydrogenase gene expression The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing Dihydropyrimidine dehydrogenase (DPD) expression levels in tissues and prognosticate the... | 10/18/2005 |
| 6936414 | Nucleic acid isolation method and kit Provided herein is a method for separating nucleic acid from a test sample comprising the steps of contacting a test sample with a metal oxide support material and a binding buffer to form nucleic acid/metal oxide support material complexes, separating the complexes... | 08/30/2005 |
| 6927282 | Clarification of protein precipitate suspensions using anionic polymeric flocculants Protein suspensions comprising soluble and insoluble components are purified via flocculation with anionic polymers, such as polyacrylamides, potato starch, or modified cellulose. The procedure improves the efficiency of solid/liquid separations and can minimize or ... | 08/09/2005 |
| 6921478 | Dissolved air flotation system A dissolved air flotation system and method for purifying fresh water. The system is self-contained within a standard shipping container, with all components disposed in-line within the shipping container. Float is removed from the flotation tank with a skimmer that... | 07/26/2005 |
| 6916914 | Purification of somatotropin from transformed microorganisms This invention discloses a commercially advantageous process for extraction and purification of protein from microorganisms. The initial steps of the process are useful for purifying many insoluble proteins while later steps are designed to renature denatured somato... | 07/12/2005 |
| 6905821 | Method of determining Dihydropyrimidine dehydrogenase gene expression The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing Dihydropyrimidine dehydrogenase (DPD) expression levels in tissues and prognosticate the... | 06/14/2005 |
| 6900034 | Method for purifying recombinant proteins expressed as insoluble aggregates The invention relates to a method for solubilising and purifying recombinant proteins which are expressed in bacterial host cells and are deposited as insoluble aggregates (inclusion bodies). The purification is based on conversion of the inclusion bodies into solub... | 05/31/2005 |
| 6893639 | Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates The method for immune serum globulin purification relates to the purification of immune globulins from blood plasma with a high degree of efficiency and a high rate of recovery. The immune globulin source is Cohn's fraction I+II+III or II+III prepared from plasma or... | 05/17/2005 |
| 6875848 | Process for the production of virus-inactivated human gammaglobulin G The gammaglobulin is extracted from a fraction isolated by fractionation with ethanol in the presence of a carbohydrate, and after reducing the content of contaminants with PEG, it is applied to an anionic resin exchange column, an effluent being obtained in which t... | 04/05/2005 |
| 6875617 | Agent for protein precipitation, a method of protein precipitation, a method of protein assay using protein precipitation agent, and a kit for protein assay A method of protein precipitation, concentration and removal of non-protein agents from the protein solution wherein the protein solution is treated with a protein-precipitation agent containing an acidic agent, a salt and a precipitate forming agent. After precipit... | 04/05/2005 |
| 6852833 | Artificial chaperon kit The present invention provides an artificial chaperon useful for refolding the proteins having low voluntary folding ability and being difficult or unable to be a native form without a second (or assistant) of a molecular chaperon in a short time, and folding said p... | 02/08/2005 |
| 6756482 | Purified human activin and process for producing the same The present invention provides a process for purifying human activin by cation exchange chromatography and chaotropic ion concentration gradient elution. ... | 06/29/2004 |
| 6737233 | Method for preparing HCV E2 binding protein A 24 kd percent capable of binding the E2 envelope protein of hepatitis C virus (HCV), and functionally equivalent variants or fragments of the 24 kd protein, are disclosed. Processes for production and purication of the 24 kd protein, and functionally equivalent va... | 05/18/2004 |
