Did You Know...
...that two musicians were responsible for the invention of color print film? Fascinated by photography, Leopold Godowsky and Leopold Mannes worked together to produce an easy-to-use, practical color film. They worked full time as music teachers and gave concerts while experimenting during their off hours in Mannes' kitchen. Their success earned them full-time, well-paying jobs at Kodak and their efforts resulted in Kodachrome film, which was introduced in 1935.
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| Number | Title | Issue Date |
| 7626004 | Protein purification The present invention relates to a method of purifying a protein of interest from its fusion analog, comprising obtaining a protein solution comprising a protein of interest and its fusion analog; adjusting the pH and/or ionic strength of the protein solution with a... | 12/01/2009 |
| 7547770 | Colostral fractionation process A method (100) and a system (200) for processing mammalian bodily fluids to isolate target peptides and proteins. The method can include the steps of passing a mammalian bodily fluid through at least one ion exchange column (204). The ion exchan... | 06/16/2009 |
| 7528240 | Method for producing human anti-thymocyte immunoglobulins Methods for producing improved anti-human thymocyte immunoglobulins from specific-pathogen-free animals are provided, without the need for an adsorption step on human tissues and the consequent drawbacks of such a step. ... | 05/05/2009 |
| 7442779 | Isolation of proteins The present invention relates to a novel method for the isolation or purification of immunoglobulins (a special class of proteins) from a solution containing immunoglobulins, e.g. hybridoma cell culture supernatants, animal plasma or sera, or colostrum. The method i... | 10/28/2008 |
| 7422863 | Molting hormone receptor and method for screening ligand to the receptor The present invention provides a completely novel molting hormone receptor, which is used for efficiently screening a substance that can be applied to a disinfestant or the like. An insect molting hormone receptor comprising the following polypeptide (a) and polypep... | 09/09/2008 |
| 7408045 | Adsorbent of high-mobility-group protein and body fluid-purification column An adsorbent of high-mobility-group proteins (HMG protein) which can remove HMG protein in body fluid is disclosed. The adsorbent according to the present invention has a water-insoluble carrier on which (a) substance(s) having (a) hydrogen-bondable functional group... | 08/05/2008 |
| 7396468 | Methods and system for protein separation The present disclosure relates to a system and method for membrane protein separation including: fractionating a membrane sample on a reversed-phase superficially porous stationary phase at a temperature of greater than or equal to about 40° C. to recover a protein... | 07/08/2008 |
| 7338935 | Chromatographic separation of therapeutic polypeptides The present invention is directed to the purification and commercialization of therapeutic polypeptides that have. In one aspect of the invention, a method of purifying Interferon β-1b using size exclusion chromatography is provided. In another aspect of the invent... | 03/04/2008 |
| RE40070 | Antibody purification This invention relates to the application of hydrophobic interaction chromatography combination chromatography to the purification of antibody molecule proteins.The questions raised in reexamination request, 09/006,966 filed Mar. 12, 2004 have been considered and th... | 02/19/2008 |
| 7329353 | LC/MS method of analyzing high molecular weight proteins The present invention is directed to a novel method of analysis of high molecular weight proteins. More specifically, it is directed to a novel reversed-phase LC/MS method of analysis of high molecular weight proteins including antibodies. ... | 02/12/2008 |
| 7329409 | Compositions and methods for treatment of microbial infections The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The invention comprises administration of an effective amount of bacterial lysate compositions for the treatment of pa... | 02/12/2008 |
| 7320728 | Rod-shaped apatite crystals having a specific length-to-width ratio The rod-shaped apatite crystals of the formula Ca5(PO4)3(OH)xFy have the following features a) the length-to-breadth ratio of the crystals is at least ≧5 and b) x+y=1, where if x or y... | 01/22/2008 |
| 7316919 | Composite materials comprising supported porous gels This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked... | 01/08/2008 |
| 7300772 | BMP products Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair. ... | 11/27/2007 |
| 7284668 | Microporous membrane substrate having caustic stable, low protein binding surface The present invention provides porous media or membranes having a surface coating that includes a first coating of a cross-linked terpolymer and a second coating comprising a copolymer or a terpolymer modified with a hydrophilic or hydrophobic functional group which... | 10/23/2007 |
| 7276590 | Ion exchange chromatography of proteins and peptides The present invention relates to an ion exchange chromatography process for purifying a peptide from a mixture containing the peptide and related impurities, and to an industrial method including such ion exchange chromatography process. ... | 10/02/2007 |
| 7268208 | Morphogen solubilizing peptides Disclosed are novel compositions of morphogenic proteins constituting soluble forms of these proteins, antibodies that distinguish between soluble and mature forms, and method for producing these morphogenic proteins and antibodies. ... | 09/11/2007 |
| 7229959 | Supplemented fibrin matrix delivery systems This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one antibody. The composition may be further supplemented with, for example, one... | 06/12/2007 |
| 7223848 | Methods for purifying Fc-containing proteins The present invention provides a process for dissociating Fc-containing molecules from complexes of Protein A/Fc-containing molecules or mixtures containing Fc-containing molecules and Protein A. The association, e.g., by hydrophobic interactions, between the Fc-con... | 05/29/2007 |
| 7223826 | Amide-functional polymers, compositions, and methods Amide-functional polymers, and compositions including such polymers, are disclosed. The compositions, which optionally may be hardenable, are useful for treating a surface. ... | 05/29/2007 |
| 7223561 | Process of high purity albumin production A process is provided for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, host proteins, fragments of albumin, polymers or aggregates of albumin and viruses, and which is essentially non-g... | 05/29/2007 |
| 7217691 | Methods of treatment of periodontal disease Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair. ... | 05/15/2007 |
| 7214778 | Glycoprotein with antidiabetic, antihypertensive, antiobesity and antihyperlipidemic effects from , and a method for preparing same A glycoprotein extracted from the fruiting body of Grifola frondosa is demonstrated to have antidiabetic, antihypertensive, antiobesity and antihyperlipidemic effects, and has great potential as an active component for pharmaceuticals, dietary supplements or ... | 05/08/2007 |
| 7208179 | Methods for treating disease and forming a supplemented fibrin matrix This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one oligonucleotide. The composition may be further supplemented with, for examp... | 04/24/2007 |
| 7208585 | Protein purification The present invention relates to a method of purifying a protein of interest from its fusion analog, comprising obtaining a protein solution comprising a protein of interest and its fusion analog; adjusting the pH and/or ionic strength of the protein solution with a... | 04/24/2007 |
| 7202211 | Methods of preventing or treating brain ischemia or brain injury The present invention relates to use of Narp inhibitor in order to promote or enhance recovery from ischemic events, particularly focal ischemia of the central nervous system, as well as for preventing or diminishing chronic degenerative changes. ... | 04/10/2007 |
| 7195923 | Ratiometric determination of glycated protein The present invention provides methods for determining a ratio of an amount of a glycated form of a protein to a total amount of the protein in a sample containing the glycated protein, the glycosylated protein, or the glycoprotein. The method incorporates lateral f... | 03/27/2007 |
| 7196054 | Methods for treating wound tissue and forming a supplemented fibrin matrix This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one antimicrobial composition. The composition may be further supplemented with,... | 03/27/2007 |
| 7193066 | Preparation of highly pure toxin fragments Toxin derivatives are prepared by proteolytic treatment of holotoxin, and their toxicity is reduced by contacting the preparation with a ligand, which can be a metal or an antibody or another ligand. This ligand selectively binds to the toxin but not to the toxin de... | 03/20/2007 |
| 7189324 | High-affinity, low molecular-mass displacers for ion-exchange chromotography A method for separating one or more components of a biomolecule mixture by means of an ion exchange chromatographic system operated in the displacement mode includes sequentially perfusing the system with a first solution including the biomolecule mixture, and a sec... | 03/13/2007 |
| 7189410 | Supplemented and unsupplemented tissue sealants, methods of their production and use This invention provides a fibrin sealant bandage, wherein said fibrin sealant may be supplemented with at least one composition selected from, for example, one or more regulatory compounds, antibody, antimicrobial compositions, analgesics, anticoagulants, antiprolif... | 03/13/2007 |
| 7186811 | Osteogenic device and a method for preparing the device The present invention is related to an osteogenic device and its preparation. Said device comprises a bone morphogenetic protein (BMP), preferably a modified BMP complex obtainable by a modification of the conventional guanidum hydrochloride extraction method and co... | 03/06/2007 |
| 7179592 | Size-exclusion-based extraction of affinity ligands and active compounds from natural samples The invention encompasses an improved, rapid, size-exclusive method for screening for small molecular weight ligands that bind specifically to a protein target, using size-exclusion separation, ultrafiltration, and mass spectrometry. ... | 02/20/2007 |
| 7169298 | Method and apparatus for separating polynucleotides using monolithic capillary columns Methods and devices based on capillary monolithic columns, preferably consisting of an underivatized poly(styrene-divinylbenzene) monolith, for separating a mixture of polynucleotides by ion pair-reverse phase-high performance chromatography (IP-RP-HPLC). In various... | 01/30/2007 |
| 7157557 | Increased recovery of active proteins The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase ... | 01/02/2007 |
| 7153482 | Rod shaped apatite crystals having a specific length-to-width ratio The rod-shaped apatite crystals of the formula Ca5(PO4)3(OH)xFy have the following features a) the length-to-breadth ratio of the crystals is at least ≧5 and b) x+y=1, where if x or y... | 12/26/2006 |
| 7136759 | Method for enhanced accuracy in predicting peptides using liquid separations or chromatography A method for predicting the elution time of a peptide in chromatographic and electrophoretic separations by first providing a data set of known elution times of known peptides, then creating a plurality of vectors, each vector having a plurality of dimensions, and e... | 11/14/2006 |
| 7122344 | Methods for the production of purified recombinant human uteroglobin for the treatment of inflammatory and fibrotic conditions The present invention relates generally to the production of recombinant human uteroglobin (rhUG) for use as a therapeutic in the treatment of inflammation and fibrotic diseases. More particularly, the invention provides processes, including broadly the steps of bac... | 10/17/2006 |
| 7119166 | Universal procedure for refolding recombinant proteins A universal folding method that has been demonstrated to be effective in refolding a variety of very different proteins expressed in bacteria as inclusion bodies has been developed. Representative proteins that can be dissolved and refolded in biologically active fo... | 10/10/2006 |
| 7098026 | Human desert hedgehog protein Disclosed are a novel hedgehog protein, i.e., a Desert hedgehog protein of human origin including mature and precursor forms, a DNA encoding the protein, a monoclonal antibody recognizing the protein, a process for producing the protein, and a method for detecting t... | 08/29/2006 |
