Quotables
"We are probably nearing the limit of all we can know about astronomy."
Simon Newcomb, astronomer ; 1888
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7608697 | Protein hydrolysates enriched in peptides having a carboxy terminal proline residue A method of enzymatically producing a protein hydrolysate from a protein substrate is described, wherein a proline-specific endoprotease or a composition containing a proline-specific endoprotease and optionally a subtilisin or a metallo endoprotease, and other enzy... | 10/27/2009 |
| 7358088 | Peptides and compositions which modulate apoptosis The present invention is directed to novel peptides and compositions capable of modulating apoptosis in cells, and to methods of modulating apoptosis employing the novel peptides and compositions of the invention. In one aspect, the invention is directed to a novel ... | 04/15/2008 |
| 7183391 | Kunitz domain polypeptide zkun10 We claim the proteinase inhibitors comprising a Kunitz domain, wherein the Kunitz domain comprises amino acid residues 57–107 of SEQ ID NO: 2. We also claim a fusion protein comprising said Kunitz domain. In addition, we claim a method of inhibiting protease degra... | 02/27/2007 |
| 7166708 | Process for preparing conjugate vaccines and the conjugate vaccines This invention relates to a process for preparing a hapten-protein-polysaccharide conjugate and a hapten-protein conjugate by reacting a protein with a hapten to produce a hapten-protein conjugate, followed by reacting the hapten-protein conjugate with a polysacchar... | 01/23/2007 |
| 7091180 | Hyaluronic acid and chondroitin sulfate based hydrolyzed collagen type II and method of making same Hydrolyzed collagen type II powder compositions for inducing cartilage formation in an individual, method of preparing the compositions and use of the compositions in treating connective tissue disorder, replenishing skin viscoelasticity. The compositions are admini... | 08/15/2006 |
| 7067483 | Pharmaceutical compositions containing a gycopeptide antibiotic and a cyclodextrin Disclosed are pharmaceutical composition containing a cyclodextrin and a therapeutically effective amount of a glycopeptide antibiotic or a salt thereof. Also disclosed are methods of treating a bacterial disease in a mammal by administering said pharmaceutical comp... | 06/27/2006 |
| 7026167 | Systems and methods for the analysis of protein phosphorylation The present invention relates to a method of applying mass spectrometry to analyzing peptides or proteins, especially in the proteome setting. More particularly, the invention relates to a mass spectrometry-based method for detection of protein/peptide phosphorylati... | 04/11/2006 |
| 7026288 | Pharmaceutical compositions containing a glycopeptide antibiotic and a cyclodextrin Disclosed are pharmaceutical compositions containing a cyclodextrin and a therapeutically effective amount of a glycopeptide antibiotic or a salt thereof. Also disclosed are methods of treating a bacterial disease in a mammal by administering such pharmaceutical com... | 04/11/2006 |
| 6858584 | Pharmaceutical compositions containing a glycopeptide antibiotic and a cyclodextrin Disclosed are pharmaceutical compositions containing a cyclodextrin and a therapeutically effective amount of a glycopeptide antibiotic or a salt thereof. Also disclosed are methods of treating a bacterial disease in a mammal by administering such pharmaceutical com... | 02/22/2005 |
| 6838259 | Process for producing kiss-1 peptide A KiSS-1 peptide or a salt thereof can be produced in a large scale by subjecting a fusion protein or peptide in which a KiSS-1 peptide is ligated to the N-terminal of a protein or peptide having cysteine at the N-terminal, to the reaction of cleaving the peptide bo... | 01/04/2005 |
| 6815533 | Cryogranulation of activated protein C The present invention is directed at a method of processing an aqueous solution of protein C into a state suitable for storage, handling, and recovery. The present invention provides aqueous activated protein C solutions and an improved method of processing such sol... | 11/09/2004 |
| 6800736 | Hydrolyzed jojoba protein Hydrolyzed jojoba protein is provided which can be used in a variety of cosmetic formulations to enhance the desirable properties thereof. The preferred hydrolyzed jojoba is in the form of an aqueous dispersion containing a mixture of amino acids, peptides and/or pr... | 10/05/2004 |
| 6756041 | Process for preparing conjugate vaccines including free protein and the conjugate vaccines, immunogens, and immunogenic reagents produced by this process A process for preparing a protein-polysaccharide conjugate includes reacting a protein with a polysaccharide to produce a mixture including a protein-polysaccharide conjugate and free protein. At least one unreacted reagent or low molecular weight component is remov... | 06/29/2004 |
| 6716599 | Method of hydrolyzing defatted jojoba meal with protease enzymes Hydrolyzed jojoba protein is provided which can be used in a variety of cosmetic formulations to enhance the desirable properties thereof. The preferred hydrolyzed jojoba is in the form of an aqueous dispersion containing a mixture of amino acids, peptides and/or pr... | 04/06/2004 |
| 6552171 | Hydrolyzed jojoba protein Hydrolyzed jojoba protein is provided which can be used in a variety of cosmetic formulations to enhance the desirable properties thereof. The preferred hydrolyzed jojoba is in the form of an aqueous dispersion containing a mixture of amino acids, peptide... | 04/22/2003 |
| 6551997 | Engineered polypeptides in personal care applications The present invention is directed to process for conditioning hair and skin in which the skin has applied to it a polypeptide having between 20 and 60 amino acids in a polypeptide, having cysteine as at least 10% of the amino acids units and proline as at... | 04/22/2003 |
| 6506577 | Synthesis and crosslinking of catechol containing copolypeptides The synthesis of moisture-resistant adhesive polypeptides, conditions for their use, and conditions for controlling characteristics of the crosslinked matrix are disclosed. By specifically manipulating the conditions under which these networks are formed,... | 01/14/2003 |
| 6395508 | Peptide mixture and products thereof A method for producing a peptide mixture from a starting protein by (1) adding at least one protease to an aqueous solution of at least one starting protein to hydrolyse the starting protein, (2) measuring the amount of a free amino acid selected from the... | 05/28/2002 |
| 6323319 | Method of making hydrolyzed collagen type II Hydrolyzed collagen type II powder compositions, method of preparing the compositions and use of the compositions in treating cartilage defects. The compositions are orally administered to an individual in need of cartilage augmentation in a daily dosage ... | 11/27/2001 |
| 6248334 | Process for preparing conjugate vaccines including free protein and the conjugate vaccines, immunogens, and immunogenic reagents produced by this process A process for preparing a protein-polysaccharide conjugate includes reacting a protein with a polysaccharide to produce a mixture including a protein-polysaccharide conjugate and free protein. At least one unreacted reagent or low molecular weight compone... | 06/19/2001 |
| 6172262 | Amphiphilic agents for membrane protein solubilization Disclosed are amphiphilic compounds comprising Formula I: ##STR1## wherein R1, R2, and R3 are C2 -C12 straight or branched alkyl; unsubstituted phenyl, biphenyl, C3 -C8 cycloalky... | 01/09/2001 |
| 6132729 | Combined tissue factor and chemotherapeutic methods and compositions for coagulation and tumor treatment The invention embodies the surprising discovery that Tissue Factor (TF) compositions and variants thereof specifically localize to the blood vessels within a vascularized tumor following systemic administration. The invention therefore provides methods an... | 10/17/2000 |
| 6132730 | Combined tissue factor and factor VIIa methods and compositions for coagulation and tumor treatment The invention embodies the surprising discovery that Tissue Factor (TF) compositions and variants thereof specifically localize to the blood vessels within a vascularized tumor following systemic administration. The invention therefore provides methods an... | 10/17/2000 |
| 6103882 | Method of producing a 19P2 ligand The method of the present invention is suitable for the commercial high-level production of a protein or peptide which can be used as a prophylactic and therapeutic drug for various diseases such as senile dementia, cerebrovascular dementia (dementia aris... | 08/15/2000 |
| 6090912 | Topologically segregated, encoded solid phase libraries comprising linkers having an enzymatically susceptible bond The invention relates to libraries of synthetic test compound attached to separate phase synthesis supports. In particular, the invention relates to libraries of synthetic test compound attached to separate phase synthesis supports that also contain codin... | 07/18/2000 |
| 6077951 | Glycosylhydrazines preparation immobilization and reactions of glycoprotein analysis and O-glycan removal The present invention consists in methods of preparing derivatives either isolation or from glycopeptides or glycoproteins. The methods comprise producing sugar hydrazones, sugar pyrazoles, glycosylpyrazones, azoglycan dyes and hydrazoglycan dyes. The pre... | 06/20/2000 |
| 6074837 | Assays using a soluble fibrin-like monomer An assay method that requires a soluble fibrin monomer or a soluble fibrin monomer reagent as one of the components of the assay. The reagent is a fibrin-like material having a solubility and stability similar to fibrinogen in that it remains soluble and ... | 06/13/2000 |
| 6060269 | Method of producing a peptide mixture The present invention relates to a method for industrial production of a peptide preparation having specific specifications by hydrolysis of a protein material, preferably based on whey. The method comprises several steps, which makes it easy to control t... | 05/09/2000 |
| 6051687 | Purification of liquid protein hydrolysate and the resultant products A method for removing excess salts, sulfites, sulfates and fatty components from liquid protein hydrolysate is described. Purified liquid protein products having reduced concentrations of salts, sulfites, sulfates and fatty material are also described. Th... | 04/18/2000 |
| 5994518 | Method of producing a polypeptide having human granulocyte colony stimulating factor activity Novel hG-CSF polypeptide derivatives having an amino acid sequence derived from the amino acid sequence of the human granulocyte colony stimulating factor polypeptide by substitution of at least one amino acid by a different amino acid and/or deletion of ... | 11/30/1999 |
| 5986071 | Method for C-terminal degradation of peptides and proteins A method for C-Terminal degradation of peptides and proteins involves forming a thiohydantoin derivative of the C-Terminal amino acid and then cleaving the derivatized amino acid by reaction with methoxide or methiolate ions.... | 11/16/1999 |
| 5952193 | Peptide mixture and products thereof A method for producing a peptide mixture from whey protein by (1) adding at least one protease to an aqueous solution of at least one whey protein to hydrolyze the whey protein, (2) measuring the amount of a free amino acid selected from the group consist... | 09/14/1999 |
| 5935815 | Process for micro biological production of proteins The invention is based on the finding that furin belongs to a family of endoproteolytically active enzymes and relates to a process in the in vitro cleavage of a protein by treating the protein in the presence of Ca2+ ions with furin, or an en... | 08/10/1999 |
| 5849882 | Methods for the preparation of bioactive peptides by protein hydrolysis The present invention relates to improved methods for the production of bioactive peptides. Specifically the present invention relates to improved methods for the chemical hydrolysis of proteins by organic acids in the presence of metallic ions.... | 12/15/1998 |
| 5834596 | Process for purifying ApoA or ApoE A process for purifying apolipoprotein A (ApoA) or apolipoprotein E (ApoE), or variants or mixtures thereof, comprises contacting a first aqueous solution comprising ApoA or ApoE and endotoxins with a matrix comprising an immobilized compound with an end ... | 11/10/1998 |
| 5827934 | Cytotoxic diphtheria toxin fragments This invention relates to a modified diphtheria toxin (DT) and method of preparing the same in which two carboxy-terminal truncated forms of DT are prepared by specific chemical proteolysis generating two new proteins HA51DT and HA48DT which can be chemic... | 10/27/1998 |
| 5817764 | Cell culture substrates and methods of making such substracts Cell culture substrates comprising dried films of native fibrillar collagen produced by a method in which collagen fibers are hydrolyzed in acid, solubilized, and reformed as gels on porous surfaces under non-physiologic salt conditions to produce large f... | 10/06/1998 |
| 5780439 | Whey protein hydrolysates and mixtures thereof with casein and/or soy protein hydrolysates A whey protein hydrolysate is described which is free of allergenics while preserving the structures susceptible of exerting anticipatory regulations to maximize the tolerance and protein metabolism, and mixtures thereof with casein and/or soy protein hyd... | 07/14/1998 |
| 5750374 | Process for producing hydrophobic polypeptides and proteins, and fusion proteins for use in producing same Methods are disclosed for the production and purification of hydrophobic fusion proteins production and purification of said hydrophobic polypeptides, proteins or peptides. Homogeneous monomeric ଲ-amyloid peptide and tests for screening amyloid toxi... | 05/12/1998 |
| 5731417 | Cell culture substrates and method of making Cell culture substrates comprising dried films of native fibrillar collagen produced by a method in which collagen fibers are hydrolyzed in acid, solubilized, and reformed as gels on porous surfaces under non-physiologic salt conditions to produce large f... | 03/24/1998 |
