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Pet Toilet-Like Water Disk and Food Storage
One pet-friendly inventor patented "a device for watering pets, e.g., a dog or cat." The device, he helpfully noted, "has the general shape of a toilet."
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| Number | Title | Issue Date |
| 7678889 | Compositions and methods relating to ovarian specific genes and proteins The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic ovarian cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antib... | 03/16/2010 |
| 7674883 | Antibodies against cancer antigen TMEFF2 and uses thereof Described herein are methods and compositions that can be used for diagnosis and treatment of cancer. ... | 03/09/2010 |
| 7666999 | Neutral amino acid transporter and gene thereof A novel amino acid transporter molecule mediating transportation of amino acids, which are nutrients essentially required in the survival and proliferation of various normal cells constituting a living body and various pathology-associated abnormal cells such as tum... | 02/23/2010 |
| 7666998 | Cell growth inhibitor containing anti-PepT antibody The present inventors extensively studied and found that an antibody binding to PepT has cytotoxic activity and inhibits cell growth. These results suggest that an antibody binding to PepT, particularly an antibody having a cytotoxic activity, can be used as a cell ... | 02/23/2010 |
| 7666997 | Methods of treatment using NBS-1, antibodies and proteins thereto, and uses of the antibodies Antibodies that will specifically bind to NBS-1 are described. It is also shown that NBS-1 will interact with p53 responsive elements in a p53 promoter. Thus, NBS-1 can be used in subjects having a p53-dependent tumor to inhibit growth of that tumor. ... | 02/23/2010 |
| 7667000 | Antibodies to Zcytor 16 Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.” ... | 02/23/2010 |
| 7667001 | Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that... | 02/23/2010 |
| 7662924 | Beta chain-associated regulator of apoptosis The present invention provides β-subunit-Associated Regulator of Apoptosis, or BARA, polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, non-human transgenic animals, devices and meth... | 02/16/2010 |
| 7662926 | Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor The present application describes antibodies that selectively bind human FcγRIIB, with little or no binding to other human FcγRs, e.g., human FcγRIIA. The invention also provides isolated bispecific antibodies comprising an antibody that selectively binds FcγRII... | 02/16/2010 |
| 7662925 | Optimized Fc variants and methods for their generation The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants. ... | 02/16/2010 |
| 7659374 | Eph receptor Fc variants with enhanced antibody dependent cell-mediated cytotoxicity activity The present invention relates to novel Fc variants that immuno-specifically bind to an Eph receptor. The Fc variants comprise a binding region that immunospecifically binds to an Eph receptor and an Fc region that further comprises at least one novel amino acid resi... | 02/09/2010 |
| 7659375 | Human IL-1 epsilon DNA and polypeptides The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented pe... | 02/09/2010 |
| 7638603 | Antibodies against interleukin 17 receptor-like protein The present invention relates to a novel IL17RLP protein which is a member of the interleukin (IL)-17 receptor family. In particular, isolated nucleic acid molecules are provided encoding the human IL17RLP protein. IL17RLP polypeptides are also provided as are vecto... | 12/29/2009 |
| 7635758 | Antibodies directed to G-protein coupled receptor HGPRBMY29sv1 The present invention provides novel polynucleotides encoding HGPRBMY28 and HGPRBMY29 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding splice variants of HGPRBMY29 polypeptides, HGPRBMY29v1 and HGPRBMY29v2.... | 12/22/2009 |
| 7635757 | B7-4 Antibodies and uses therefor The invention provides isolated nucleic acids molecules, designated B7-4 nucleic acid molecules, which encode novel B7-4 polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing B7-4 nucleic acid molecules... | 12/22/2009 |
| 7632922 | Osteoprotegerin The present invention discloses a novel secreted polypeptide, termed osteoprotegerin, which is a member of the tumor necrosis factor receptor superfamily and is involved in the regulation of bone metabolism. Also disclosed are nucleic acids encoding osteoprotegerin,... | 12/15/2009 |
| 7619069 | Antibodies to TGF-beta 1 TGF-beta 1 binding compositions and reagents related thereto are provided. Methods of using such compositions for therapeutic purpose are also provided. ... | 11/17/2009 |
| 7619068 | Ovr110 antibody compositions and methods of use The invention provides isolated anti-ovarian, pancreatic, lung or breast cancer antigen (Ovr110) antibodies that internalize upon binding to Ovr110 on a mammalian in vivo. The invention also encompasses compositions comprising an anti-Ovr110 antibody and a carrier. ... | 11/17/2009 |
| 7615616 | Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can then be utilized in method... | 11/10/2009 |
| 7612178 | Anti-IGF-1R antibodies and uses thereof The invention relates to antibodies which bind to insulin like growth factor receptor-1 (IGF-1R) and uses thereof, in particular in the diagnosis and treatment of cancer. Specific human and murine monoclonal antibodies which inhibit IGF-1R-mediated pro-survival and ... | 11/03/2009 |
| 7608690 | IL-B30 antibodies Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided. ... | 10/27/2009 |
| 7608691 | Antibodies against IL-16 antagonist peptides The present invention has found that a series of peptides having sequences that substantially correspond to specific regions of the C-terminus of IL-16 can inhibit the activity of IL-16. The present invention has demonstrated that such IL-16-inhibiting peptides can ... | 10/27/2009 |
| 7605233 | Tumour necrosis factor binding ligands The present invention relates to ligands which bind to human tumour necrosis factor alpha (TNF) in a manner such that upon binding of these ligands to TNF the biological activity of TNF is modified. In preferred forms the ligand binds to TNF in a manner such that th... | 10/20/2009 |
| 7601813 | Anti-GL50 antibodies The invention provides isolated nucleic acids molecules, designated GL50 nucleic acid molecules, which encode novel GL50 polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing GL50 nucleic acid molecules... | 10/13/2009 |
| 7598349 | Antibodies to peptide fragments having cell death-inhibitory activity The present invention provides a peptide fragment or a series of peptide fragments having a cell death-inhibitory activity, having the amino acid sequence consisting of 103 amino acid residues at the C-terminal of selenoprotein P, or having said amino acid sequence ... | 10/06/2009 |
| 7589179 | IL-7 variants with reduced immunogenicity Modified interleukin-7 (IL-7) polypeptides are disclosed. The modified IL-7 polypeptides have alterations to one or more potential T-cell epitopes, thereby to reduce a T-cell response. ... | 09/15/2009 |
| 7582734 | Functional antibodies that specifically bind to the Chemerin receptor The present invention relates to a G-protein coupled receptor and a novel ligand therefor. The invention provides screeing assays for the identification of candidate compounds which modulate the activity of the G-protein coupled receptor, as well as assays useful fo... | 09/01/2009 |
| 7582733 | Humanized antibodies that recognize beta amyloid peptide The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Aβ in the brain of a patient. Preferred agents include humanized antibodies. ... | 09/01/2009 |
| 7582735 | Feline immunoglobulin E molecules and related methods The invention relates to: nucleic acid molecules encoding the light chain and heavy chain of feline immunoglobulin E (IgE), including species-specific regions of feline IgE; proteins encoded by the nucleic acid molecules; inhibitors to the nucleic acids and proteins... | 09/01/2009 |
| 7579445 | Reagents and methods for inducing an immune response to prostate specific antigen The invention is an apparatus and method for the treatment of prostate cancer, and involves administering an antibody that specifically binds with prostate antigen. ... | 08/25/2009 |
| 7576184 | Allergenic proteins of natural rubber latex, their production and use in assays This invention relates to allergenic proteins of natural rubber latex in substantially purified form, their production and their use, together with monoclonal antibodies developed against those allergenic proteins, in assays for the qualitative and quantitative dete... | 08/18/2009 |
| 7576182 | Compositions and methods for the treatment of immune related diseases The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases. ... | 08/18/2009 |
| 7576183 | Structure-based receptor MIMICS targeted against bacterial superantigen toxins The invention provides therapeutic compositions useful in the treatment of bacterial superantigen mediated conditions, such as Toxic Shock Syndrome. The compositions comprise genetically engineered bifunctional polypeptides containing a specific T-cell receptor bind... | 08/18/2009 |
| 7576185 | PRO34128 antibodies The present invention is directed to novel polypeptides having sequence similarity to GDNFR and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molec... | 08/18/2009 |
| 7572895 | Transferrin receptor antibodies The invention provides further characterization of the disease and cancer-associated antigen, transferrin receptor. The invention also provides a novel family of antibodies that bind to the transferrin receptor, methods of diagnosing and treating various human cance... | 08/11/2009 |
| 7572896 | Antibodies to oncostatin M receptor The invention provides characterization of the disease and cancer-associated antigen, OSM-Rβ The invention also provides modulators of OSM-R.beta, including a family of monoclonal antibodies that bind to antigen OSM-R.beta, and methods of diagnosing and treating va... | 08/11/2009 |
| 7569672 | Antibodies that bind to EphA2 and methods of use thereof Provided herein is disclosure about the development and characterization of an antibody that binds to antigen EphA2 which is present on a variety of human cancers from breast, lung, prostate, and colons. Methods of diagnosing and treating various cancers by using su... | 08/04/2009 |
| 7566770 | Humanized collagen antibodies and related methods The invention provides an antibody, or functional fragment thereof, a grafted antibody, or functional fragment thereof, comprising one or more complementarity determining regions (CDRs) having at least one amino acid substitution in one or more CDRs of a heavy chain... | 07/28/2009 |
| 7560531 | Cln101 antibody compositions and methods of use alone and in combination with prostate specific antigen and other cancer markers This invention relates to a method for assessing risk of prostate and/or ovarian cancer. Specifically, in one embodiment it relates to utilizing both Cln101 and Prostate Specific Antigen (PSA) in combination to determine the risk of prostate cancer. In an alternativ... | 07/14/2009 |
| 7560532 | Smad6 and uses thereof The invention includes nucleic acids encoding the Smad6 protein, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such nucleic acids, and antibodies relating thereto. Methods and produc... | 07/14/2009 |