...During the Civil War, the Confederacy established its own Patent Office which issued 266 patents, a third of which concerned implements of war.
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| Number | Title | Issue Date |
| RE39705 | Method of treating glutathione deficient mammals Glutathione (GSH) is a tripeptide of extreme importance as a catalyst, reductan, and reactant. It can be depleted intra-cellularly either by forming a direct complex with an electrophilic agent (accomplished investigationally by agents such as bromobenzene or diethy... | 06/26/2007 |
| 7183108 | Selection and uses of lactic acid bacteria strains modulating non-specific immunity The invention concerns lactic acid bacteria strains capable of regulating the production of NO and inflammatory cytokines by enterocytes, depending on the inflammatory condition of said enterocytes. The strains can also be incorporated in food supplements such as fe... | 02/27/2007 |
| 7144855 | Protein complex from ion-exchange chromatography for treatment of bacterial infections The present invention relates to the use of alpha-lactalbumin in the preparation of preparations to be used in therapeutic or prophylactic treatment and/or for diagnostic use for infections, preferably of the respiratory tract, caused by bacteria, in particular S... | 12/05/2006 |
| 7129210 | Tissue adhesive sealant A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive with the aldehyde cross-links to form a seal. The sealant is well suited... | 10/31/2006 |
| 7053185 | Lactalbumin production process A method for producing an oligomeric form of α-lactalbumin which is in the molten globule-like state is described. The method suitably comprises exposing a source of α-lactalbumin in which the α-lactalbumin is preferably in the molten globule-like state, to an io... | 05/30/2006 |
| 6849593 | Bifidogenic peptides Pepetides having bifidogenic properties are obtainable by the process of adding proteases to cow'milk or human milk, followed by incubation, centrifugation, acidification, purification by reverse phase HPLC and cation-exchange HPLC, culturing Bifidobacterium bifi... | 02/01/2005 |
| 6815419 | Antiulcer agent The present invention provides antiulcer agents which can be orally administered while producing few side effects. These antiulcer agents contain α-lactalbumin as an active ingredient, preferably in an amount of at least 0.5 mg/g. ... | 11/09/2004 |
| 6808930 | Therapeutic agents An agent comprising a protein complex comprising an oligomeric form of α-lactalbumin (MAL) and a further reagent which is combined with MAL such that it is carried into the nucleoplasm of cells which are susceptible to MAL. Agents of the type, where the further rea... | 10/26/2004 |
| 6677433 | Stabilization of hypoallergenic, hyperdigestible previously reduced proteins Disulfide proteins showed mitigated allergenicity and increased digestibility by pepsin following reduction by thioredoxin. The sulfhydryl groups newly formed on reduction by thioredoxin (at 4° C.) or dithiothreitol (DTT) (at 55° C.) were blocked with a... | 01/13/2004 |
| 6620778 | Cysteine/glycine rich peptides Described is a method for the preparation of a mixture of peptides having a cysteine content between 7-20 w/w % from a protein source, comprising cysteine containing proteins, comprising the steps of: a) cleaving the proteins of the protein source into pep... | 09/16/2003 |
| 6599874 | Protein complex from ion-exchange chromatography of casein for treatment of bacterial infections Antibacterial protein complexes designated as Anti-adhesive Lactalbumin Like Protein (ALLP) are obtained by ion-exchange chromatography of casein and alpha-lactalbumin. Casein isolated from human milk by acid precipitation is subjected to ion-exchange chr... | 07/29/2003 |
| 6551636 | Modification of foaming properties of proteins The present invention provides methods for modifying whey protein preparations to improve their foaming and other functional properties utilizing limited proteolytic hydrolysis. The invention also provides modified whey protein preparations and and food p... | 04/22/2003 |
| 6518241 | Shock heat treatment of polypeptides The present invention relates to a method of shock heat treatment of polypeptides, to a stable polypeptide in a fluid medium, to a pharmaceutical composition comprising a stable polypeptide, to use of shock heat treatment for stabilizing a polypeptide, an... | 02/11/2003 |
| 6355612 | Protein material for slow digestion and its use The subject of the invention is the use of a protein material whose rate of digestion has been reduced, for the preparation of an enteral composition which makes it possible to modulate the postprandial plasma amino acid level, said protein material havin... | 03/12/2002 |
| 6270827 | Infant formula compositions and method of making Compositions containing human milk proteins, including the so-called host resistance factors of human milk, prepared by chemically synthesizing the human milk proteins or by genetic engineering techniques for producing recombinant human milk proteins, are... | 08/07/2001 |
| 6261624 | Thermal and PH stable protein thickening agent and method of making the same A dry protein product useful as a thickening agent and fat substitute is provided. The powder can be readily reconstituted at room temperature, or refrigerated conditions, and can be used in frozen or refrigerated foods, at room temperature, and in cookin... | 07/17/2001 |
| 6262019 | Method of treatment of glutathione deficient mammals Glutathione (GSH) is a tripeptide of extreme importance as a catalyst, reductan, and reactant. It can be depleted intracellulary either by forming a direct complex with an electrophilic agent (accomplished investigationally by agents such as bromobenzene ... | 07/17/2001 |
| 6165470 | Albumin derivatives with therapeutic functions Utilization of albumin as a stable plasma transporter with a therapeutic function that is derived from a membrane receptor. The present invention is exemplified by the description of new therapeutic agents that can be used in the treatment of Acquired Imm... | 12/26/2000 |
| 6020015 | Infant formula compositions and nutrition containing genetically engineered human milk proteins Compositions containing human milk proteins, including the so-called host resistance factors of human milk, prepared by chemically synthesizing the human milk proteins or by genetic engineering techniques for producing recombinant human milk proteins, are... | 02/01/2000 |
| 5952009 | Methods for preventing the transmission of or treating patients infected with herpesvirus A method of preventing the transmission of or treating herpesvirus, such as herpes simplex virus infection, or Chlamydia trachomatis comprising administering to a patient a composition which comprises: (i) a protein or peptide containing lysines and an N-... | 09/14/1999 |
| 5925737 | Whey protein fractionation using high pressure or supercritical carbon dioxide A process for the fractionation of proteins from an aqueous solution of whey is described. The process includes mixing the solution with carbon dioxide under pressure, heating the mixture to increase the pressure, releasing the pressure and lowering the t... | 07/20/1999 |
| 5888552 | Anti-cancer therapeutic compositions containing whey protein concentrate This invention relates to a method of treatment of patients having lesions resulting from cancer cells and to an application as an anti-cancer composition of undenatured whey protein concentrate.... | 03/30/1999 |
| 5780439 | Whey protein hydrolysates and mixtures thereof with casein and/or soy protein hydrolysates A whey protein hydrolysate is described which is free of allergenics while preserving the structures susceptible of exerting anticipatory regulations to maximize the tolerance and protein metabolism, and mixtures thereof with casein and/or soy protein hyd... | 07/14/1998 |
| 5747647 | Process for the fractionation of whey constituents A process for fractionation of dairy whey is described which enables various whey constituents, in particular, alpha-lactalbumin and beta-lactoglobulin, to be recovered in substantially pure form. Lactose may also be recovered. The mineral content of raw ... | 05/05/1998 |
| 5710132 | Use of bovine colostral milk as a preparation for the protection of the liver The invention relates to the use of colostral milk or colostral milk preparations from the cow, or fractions containing immunoglobulin prepared therefrom, as a liver protective preparation for the prevention and treatment of liver function disturbances in... | 01/20/1998 |
| 5707968 | Inhibition of attachment of H.influenzae to human cells The attachment of H. influenzae to human cells, such as oropharyngeal cells, may be inhibited by native human ଲ-casein, a recombinant form of human ଲ-casein, and hydrolysates of both. The human ଲ-casein or hydrolysate may be contained in... | 01/13/1998 |
| 5679780 | Method for obtaining high-quality protein products from whey High quality protein products are obtained from whey by subjecting whey to cross flow filtration in microfilter. The whey and retentate are brought to circulate in a circulation path on one side of the membrane area of the microfilter, while whey which ha... | 10/21/1997 |
| 5643880 | Product for inhibition of attachment of H. influenzae to human cells The attachment of H. influenzae to human cells, such as oropharyngeal cells, may be inhibited by native human ଲ-casein, a recombinant form of human ଲ-casein, and hydrolysates of both. The human ଲ-casein or hydrolysate may be contained in... | 07/01/1997 |
| 5561109 | Method for the healing of wounds caused by corneal injury A method for the healing of wounds caused by corneal injury, which includes administering to a mammalian patient in need thereof an effective wound healing amount of lactoferrin, lactoperoxidase or a combination of lactoferrin and lactoperoxidase as activ... | 10/01/1996 |
| 5538952 | Inhibition of infection of mammalian cells by respiratory syncytial virus The infection of mammalian cells by RSV may be inhibited by native human ଲ-casein, a recombinant form of human ଲ-casein, and hydrolysates of both. The human ଲ-casein or hydrolysate may be contained in a liquid enteral nutritional product... | 07/23/1996 |
| 5506209 | Product for inhibition of infection of mammalian cells by respiratory syncytial virus The infection of mammalian cells by RSV may be inhibited by native human ଲ-casein, a recombinant form of human ଲ-casein, and hydrolysates of both. The human ଲ-casein or hydrolysate may be contained in a liquid enteral nutritional product... | 04/09/1996 |
| 5496802 | Control of milk secretion A protein which inhibits milk secretion by lactating cows and which is present in the eighth (6B, Figure) significant peak when a nominally 10-30 KDa fraction of the whey proteins of the milk is resolved on a "Mono Q" anion exchange column using 10 mM imi... | 03/05/1996 |
| 5480973 | Gel products and a process for making them A proteinaceous product comprises a stable, substantially clear, thermally irreversible gel formed by the reaction product of protein and reducing sugar, preferably containing from 2 to 25% gel-forming protein by weight. Particles or pieces of edible mate... | 01/02/1996 |
| 5451412 | Biologically active undenatured whey protein concentrate as food supplement The present invention is concerned with a whey protein composition comprising a suitable concentration of whey protein concentrate wherein the whey protein concentrate contains proteins which are present in an essentially undenatured state and wherein the... | 09/19/1995 |
| 5420249 | Process for the recovery of -lactalbumin and ଲ-lactoglobulin from a whey protein product This invention relates to a process for the recovery of -lactalbumin and/or ଲ-lactoglobulin enriched whey protein concentrate from a whey protein product. The process comprises the following steps: a) incubating a solution comprising whey protein ... | 05/30/1995 |
| 5322836 | Bioactive agents, compositions and materials comprising said bioactive agents Bioactive agents, having growth-promoting activity upon Bifidobacteria, consisting of one or more lactoferrin-compounds selected from the group consisting of bovine lactoferrin, bovine apolactoferrin and bovine Fe-lactoferrin, which can be used as it is a... | 06/21/1994 |
| 5290571 | Biologically active whey protein concentrate The present invention is concerned with a whey protein composition comprising a suitable concentration of whey protein concentrate wherein the whey protein concentrate contains proteins which are present in an essentially undenatured state and wherein the... | 03/01/1994 |
| 5275814 | Allergen-thymic hormone conjugates for treatment of IgE mediated allergies A protein conjugate or mixture useful in immunotherapy composed of a biological response modifier (BRM) and an allergen is disclosed. In use the protein conjugate or mixture is combined with a pharmaceutically acceptable carrier. Cytokines, bacterial, fun... | 01/04/1994 |
| 5230902 | Undenatured whey protein concentrate to improve active systemic humoral immune response This invention provides a method of improving the humoral immune response or increasing the concentration levels of glutathione in mammals, which comprises administering orally to a mammal a therapeutically or a prophylactically effective amount of undena... | 07/27/1993 |
| 5219838 | Method for inhibiting tyrosinase activity in treatment of skin An agent for tyrosinase inhibition which contains the effective quantity of enzymatic hydrolyzates of milk proteins, having a decomposition rate from 6% to 55% as expressed by the percentage of formol nitrogen to total nitrogen.... | 06/15/1993 |