Did You Know...
...that to encourage use of his new invention, the shopping cart, market owner Sylvan Goldman hired fake shoppers to push the carts around his store in Oklahoma City? Seems his customers were reluctant to give up their hand-carried baskets.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7893212 | S-nitroso group-containing albumin, method for production, and anticancer agent The present invention provides an S-nitroso group-containing albumin, comprising an S-nitroso group introduced to at least one lysine in the amino acid sequence for albumin. The S-nitro group has been introduced into a lysine in the S-nitroso group-containing albumi... | 02/22/2011 |
| 7531631 | Method for preparing human serum albumin through heat-treatment in the presence of divalent cation The present invention herein discloses a method for purifying human serum albumin, which is characterized in that it comprises the steps of heat-treating a human serum albumin-containing solution including impurities originated from a host cell, in the presence of a... | 05/12/2009 |
| 7423124 | Method for albumin purification The present invention is a method of purifying recombinant human serum albumin (rHSA) from a solution, which method comprises to subject a cell culture supernatant (CCS) comprising rHSA cation exchange on a bimodal high salt tolerant matrix; hydrophobic interaction ... | 09/09/2008 |
| 7351801 | Method, use and kit for separating albumin from contaminants in a liquid The present invention is a method of separating recombinant human serum albumin (rHSA) from low molecular weight contaminants in a liquid, which method comprises the steps of: (a) providing a separation medium, which includes anion-exchanging ligands coupled to a ba... | 04/01/2008 |
| 7332577 | Therapeutic human albumin solutions with low prekallikrein activator (PKA) activity and process for obtaining them The invention discloses a purified albumin solution of human origin with low prekallicrein activator (PKA) activity and stability over time characterised in that it has an antithrombin content equal to or greater than 0.03 mg/g of albumin, and a process for producti... | 02/19/2008 |
| 7307148 | Method for purification of albumin conjugates The present invention relates to a method for separating albumin conjugate from unconjugated albumin in a solution comprising albumin conjugate and unconjugated albumin by loading the solution onto a hydrophobic support equilibrated in aqueous buffer having a high s... | 12/11/2007 |
| 7226609 | Sodium dodecyl sulfate compositions for inactivating prions An antiseptic composition useful in destroying the infectivity of infectious proteins such as prions is disclosed. The antiseptic composition is preferably maintained at either a low pH of 4.0 or less or a high pH of 10.0 or more either of which allows for an enviro... | 06/05/2007 |
| 7220356 | Method of purifying polypeptides by simulated moving bed chromatography Provided are methods of separating an immunoreactive compound from at least one immaterial component, using a simulated moving bed (“SMB”) system and a SMB apparatus for use in these methods. Also provided are purified immunoreactive compounds prepared using the... | 05/22/2007 |
| 7216113 | Remote Execution of Materials Library Designs Methods, apparatus, and business processes enabling individual chemists to design, order, and obtain data for multiple experiments or measurements in a timely and cost-effective manner. In particular implementations, the invention includes methods and apparatus for ... | 05/08/2007 |
| 7144487 | Factor VIII separation The claims describe methods for isolating functionally active Factor VIII using a membrane-based separation system containing a separation membrane to create a first and second interstitial volume between at least two restriction membranes. One or more stabilizing a... | 12/05/2006 |
| 7087719 | Method for the crystallization of human serum albumin The present invention relates to the purification and production of human albumin from various sources through crystallization and repeated crystallization. Basic features of the invented process include providing specific reaction conditions and precipitating reage... | 08/08/2006 |
| 7084240 | Crystallization of IGF-1 Crystalline IGF-1 is provided along with a method for production thereof. Crystallizing IGF-1 comprises the steps of mixing an aqueous solution comprising IGF-1 with a reservoir solution comprising a precipitant to form a mixture; and crystallizing the mixture, opti... | 08/01/2006 |
| 7070937 | Marker useful for detection and measurement of free radical damage and method The present invention teaches a marker useful for detection and measurement of free radical damage. Specifically, the invention takes advantage of alterations which occur to the N-terminus of the albumin molecule, a circulating protein in human blood, in the presenc... | 07/04/2006 |
| 7041798 | Method for the chromatographic fractionation of plasma or serum, preparations, so obtained, and their use The invention relates to the fractionation of plasma or serum into at least one albumin fraction and one immunoglobulin fraction by hydrophobic interaction chromatography. The fractionation is carried out using an incremental salt gradient, especially an ammonium su... | 05/09/2006 |
| 7001885 | Method for removing multimers of human serum albumin Multimers of human serum albumin are removed from a solution of human serum albumin containing the multimers by bringing the human serum albumin solution into contact with an anion-exchanger equilibrated with a buffer containing a salt in a concentration ranging fro... | 02/21/2006 |
| 6951644 | Adsorbent for peptidoglycan and method and apparatus for adsorptively removing peptidoglycan An adsorbent for peptidoglycan which comprises an water-insoluble porous material having an amino group and having a molecular weight of exclusion limit of at least 50,000, and a method for removing peptidoglycan by adsorption, which comprises a step of contacting t... | 10/04/2005 |
| 6919436 | Isolation of proteins The present invention relates to a novel method for the isolation or purification of immunoglobulins (a special class of proteins) from a solution containing immunoglobulins, e.g. hybridoma cell culture supernatants, animal plasma or sera, or colostrum. The method i... | 07/19/2005 |
| 6908749 | Method for preparing human serum albumin containing heat-treatment A method for preparing human serum albumin comprises the step of heat-treating a human serum albumin solution containing contaminants at a pH value in the proximity to the isoelectric point of the contaminants. ... | 06/21/2005 |
| 6906183 | Process for the separation of glycosylated and nonglycosylated proteins A process for the partial or complete separation of glycosylated and nonglycosylated proteins is described, in which: a) a triazine dye immobilized on a matrix is incubated with a mixture of glycosylated and nonglycosylated proteins, b) the matrix is then washed to ... | 06/14/2005 |
| 6867193 | Amino acid-containing albumin preparation An albumin preparation that prevents onset of hepatic encephalopathy caused by conventional amino acid preparations and enhances an effect of improving the symptoms is provided. The albumin preparation containing amino acids is characterized in that a content of alb... | 03/15/2005 |
| 6693173 | Method to remove citrate and aluminum from proteins A method is provided for removing citrate, aluminum, and other multivalent ions and contaminants from proteins by adjusting the pH of a solution containing the protein to a pH from about 7 to about 10, and diafiltering the pH-adjusted solution against aqu... | 02/17/2004 |
| 6638740 | Process of high purity albumin production The present invention relates to a process for purifying the protein human serum albumin extracted from serum or recombinant human albumin produced by transforming a microorganism with a nucleotide coding sequence encoding the amino acid sequence of human... | 10/28/2003 |
| 6617133 | Process for purifying recombinant human serum albumin The invention provides a process for purifying recombinant human serum albumin (rHSA) by heating a-culture medium containing rHSA and the rHSA-producing host cells, feeding said heated solution upwardly into a fluidized bed in which adsorbent particles ar... | 09/09/2003 |
| 6613884 | Method for the removal/purification of serum albumins and means for use in the method A method for removing a serum albumin from a mixture of other compounds by contacting said mixture with a ligand a) having affinity for and enabling selective binding of the serum albumin and b) being attached to a base matrix insoluble in the aqueous med... | 09/02/2003 |
| 6528622 | Method of separating and recovering proteins from a protein solution A preparative method of isolating a preselected whey protein or group of whey proteins from a solution is provided. The method comprises the following steps: (a) contacting a whey protein solution with the preselected ion exchanger for a time and at a tem... | 03/04/2003 |
| 6504011 | Process for the purification of serum albumin Recombinantly produced serum albumin is purified in a series of steps, optionally by incubation with an anion-exchange adsorbent, followed by affinity chromatography employing a hydrophobic solid phase and using a water-soluble lipid anion as desorbens in... | 01/07/2003 |
| 6500918 | Conjugate comprising an antinociceptive agent covalently bonded to a blood component Conjugates are prepared from antinociceptive agents, particularly opioids or opioid analogs, more particularly dynorphins, endorphins, deltorphins, enkephalins or analogs thereof, by combining said antinociceptive agent with a material providing a functio... | 12/31/2002 |
| 6489443 | Process for the preparation of a protein solution A process for the preparation of a protein solution is described which is not prone to flock or particle formation even on heat treatment, the heat treatment being carried out in a glass vessel which has been rinsed out beforehand with a detergent solutio... | 12/03/2002 |
| 6485935 | Structure of the ankyrin binding domain of a -Na, K-ATPase The present invention provides a polypeptide of 26 amino acid residues that comprises the minimal ankyrin binding (MAB) domain. The MAB domain is responsible for the interactions between a Na,K-ATPase and ankyrin. The present invention also provides the t... | 11/26/2002 |
| 6429259 | Water soluble polymeric complex comprising a conducting polymer and a biopolymer A molecular complex which comprises a biopolymer having a plurality of ionic functional groups and a conductive polymer having charges therein. The charges bind to the ionic functional groups to form the complex. The conductive polymer is selected from th... | 08/06/2002 |
| 6372510 | Method for removing unconventional transmissible agents from a protein solution The present invention is drawn to method for removing unconventional transmissible agents (UCTA) from aqueous protein solution. This method involves treating the aqueous protein solution with simultaneous electrostatic adsorption and hydrophobic chromatog... | 04/16/2002 |
| 6350589 | Compositions of highly-purified natural mixtures of type I interferon derived from leukocytes and methods This invention relates to methods for isolating highly-purified mixtures of natural type I interferons from white blood cells. The invention also relates to highly-purified mixtures of natural type I interferons which resemble natural type I interferon in... | 02/26/2002 |
| 6183121 | Hepatitis C virus helicase crystals and coordinates that define helicase binding pockets The invention relates to the X-ray crystal structure of the hepatitis C virus helicase domain. More specifically, the invention relates to crystallized complexes of HCV helicase and an oligonucleotide, to crystallizable compositions of HCV helicase and an... | 02/06/2001 |
| 6150504 | Process for the purification of serum albumin Recombinantly produced serum albumin is purified in a series of steps, optionally by incubation with an anion-exchange adsorbent, followed by affinity chromatography employing a hydrophobic solid phase and using a water-soluble lipid anion as desorbens in... | 11/21/2000 |
| 6034221 | High purity albumin A process is provided for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, fragments of albumin, polymers or aggregates of albumin, and viruses, and which is relatively non-glyca... | 03/07/2000 |
| 6028173 | Human chromosome 16 genes, compositions, methods of making and using same This invention provides an isolated human netrin polypeptide. Netrins define a family of diffusable factors involved in axon outgrowth.... | 02/22/2000 |
| 6022954 | Process for the preparation of purified albumin solutions The invention relates to a process for preparing purified albumin from a human or animal physiological solution, such as a plasma or a plasma fraction. The process includes a process of delipidation using an anionic detergent and two chromatographic separ... | 02/08/2000 |
| 6022722 | Renaturation of proteins The invention relates to a method for the renaturation of denatured proteins in which they are treated with a renaturant which has on vicinal carbon atoms a hydroxyl group and at least one fluorine atom.... | 02/08/2000 |
| 6001974 | Method of separating albumin from serum by ion-exchange chromatography with membrane adsorbers A method of separating albumin from serum by ion exchange chromatography with membrane adsorbers characterized by high productivity and yields of high purity albumin. The separation of the albumin is carried out on highly basic anion exchange membranes an... | 12/14/1999 |
| 5994507 | Method for binding albumin and means to be used in the method A method for binding albumin by contacting an aqueous liquid containing an albumin with an albumin-binding compound is selected from albumin-binding compounds containing the scaffold --CO--NH--C(.dbd.C--)--CO--, and conjugates that are capable of binding ... | 11/30/1999 |
