Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8114963 | Fluorescent compounds Fluorescent dye compounds of formula (I) are disclosed. These compounds are useful as they interact with organic compounds in a manner such that excitation with certain wavelengths of light results in fluorescent emission. Detection and/or monitoring of the fluoresc... | 02/14/2012 |
| 8053560 | Modified human plasma polypeptide or Fc scaffolds and their uses Modified human plasma polypeptides or Fc and uses thereof are provided. ... | 11/08/2011 |
| 8022186 | Modified human plasma polypeptide or Fc scaffolds and their uses Modified human plasma polypeptides or Fc and uses thereof are provided. ... | 09/20/2011 |
| 7919591 | Modified human plasma polypeptide or Fc scaffolds and their uses Modified human plasma polypeptides or Fc and uses thereof are provided. ... | 04/05/2011 |
| 7879979 | Arginine analogs, and methods for their synthesis and use The present invention relates to novel arginine analogs, and methods for their synthesis and use. Such analogs are designed to provide a protected or free thiol (—SH) group, thereby providing a convenient linkage chemistry for coupling to a suitable group on a tar... | 02/01/2011 |
| 7732575 | Microparticles with enhanced covalent binding capacity and their uses Disclosed are proteins which are covalently bound to a solid support at a first temperature where they have a first configuration, and then biomolecules are attached to the bound proteins at a higher temperature at which the proteins have more exposed functional gro... | 06/08/2010 |
| 7528234 | Process for the preparation of doxorubicin conjugates with lactosaminated human albumin A procedure is described for conjugating the hydrazone derivatives of doxorubicin having a maleimide terminal group to lactosaminated human albumin (L-HSA). The procedure is based on the use of trialkyiphosphines to reduce the disulfide bonds of the protein and make... | 05/05/2009 |
| 7371829 | Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites The invention provides haptens, immunogens comprising such haptens coupled to an antigenicity-conferring carrier material, conjugates comprising such haptens bonded to a labelling agent as well as, antibodies raised against such immunogens and capable of binding wit... | 05/13/2008 |
| 7365162 | Stabilized bioactive peptides and methods of identification, synthesis, and use An intracellular selection system allows screening for peptide bioactivity and stability. Randomized recombinant peptides are screened for bioactivity in a tightly regulated expression system, preferably derived from the wild-type lac operon. Bioactive peptides thus... | 04/29/2008 |
| 7351800 | Stabilized albumin preparations This invention provides albumin preparations with safety and without any risk of side effects, which are free from viruses or contaminating proteins and can be stably stored over a long time while showing neither changes in appearance nor decrease in content. | 04/01/2008 |
| 7351591 | Surface modification of metals for biomolecule detection using surface enhanced Raman scattering (SERS) The present invention is based on the discovery that the methods described herein for the production of metallic colloids result in colloids exhibiting increased signal enhancement and reproducibility for the SERS detection of biomolecules. Thus, using the methods o... | 04/01/2008 |
| 7348312 | Albumin-based colloid composition and method of use in treating hypovolemia and multiorgan dysfunction A composition comprising an albumin-based colloid and its use in treating hypovolemic conditions such as capillary leak syndrome and shock are disclosed. ... | 03/25/2008 |
| 7332577 | Therapeutic human albumin solutions with low prekallikrein activator (PKA) activity and process for obtaining them The invention discloses a purified albumin solution of human origin with low prekallicrein activator (PKA) activity and stability over time characterised in that it has an antithrombin content equal to or greater than 0.03 mg/g of albumin, and a process for producti... | 02/19/2008 |
| 7332288 | Methods and reagents for the rapid and efficient isolation of circulating cancer cells A highly sensitive assay is disclosed which combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate and characterize carcinoma cells in the blood. The assay can detect one epithelial cell or less in... | 02/19/2008 |
| 7291122 | Hemofiltration methods for treatment of diseases in a mammal A hemofiltration system and method to treat an Inflammatory Mediator Related Disease in a mammal, including chronic and acute diseases, include a hemofilter and an adsorptive device. The hemofilter removes ultrafiltrate from a blood stream extracted from the mammal ... | 11/06/2007 |
| 7253259 | Protein containing serum albumin domain A protein produced by gene recombinant technology, including at least one domain selected from domains I, II, and III of serum albumin but having a different structure from that of native albumin; and a method of producing the protein. The protein has an enhanced fu... | 08/07/2007 |
| 7253147 | Modified serum albumin with reduced affinity for nickel and copper A modified serum albumin is provided which has been modified in the n-terminal region or binding region VI, such as through a truncation of at least three amino acids at the n-terminal end, so that it exhibits reduced or eliminated binding of trace metals such as ni... | 08/07/2007 |
| 7238667 | Albumin fusion proteins The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic ac... | 07/03/2007 |
| 7229782 | Antibodies specific to multiple beta blockers and methods for their use The present invention is directed antibodies specific to multiple beta blockers, as well as immunogens used to produce the antibodies and immunoassay kits and methods for using the antibodies. ... | 06/12/2007 |
| 7230085 | Anti-DOTA antibody The present invention relates to an antibody or antibody fragment that binds to 1,4,7,10-tetrazacyclododecane-N,N′,N″,N′″-tetraacetic acid (DOTA),which is bound to an alkyl-amino group through one of its pendant carb.oxyl groups. ... | 06/12/2007 |
| 7229967 | Oxygenated albumin for use as blood and blood extender The compositions described herein comprise oxygenated albumin in an aqueous sterile physiological or serum solution. The albumin is oxygenated to increase the oxygen content up to O2 saturation with clinically useful oxygen gas. The preferred oxygen-satur... | 06/12/2007 |
| 7223561 | Process of high purity albumin production A process is provided for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, host proteins, fragments of albumin, polymers or aggregates of albumin and viruses, and which is essentially non-g... | 05/29/2007 |
| 7220356 | Method of purifying polypeptides by simulated moving bed chromatography Provided are methods of separating an immunoreactive compound from at least one immaterial component, using a simulated moving bed (“SMB”) system and a SMB apparatus for use in these methods. Also provided are purified immunoreactive compounds prepared using the... | 05/22/2007 |
| 7216041 | Methods of using the structure coordinates of molecules comprising an IMPDH-like binding pocket The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site binding pockets of IMPDH. Such data storage material is capable of displaying such molecul... | 05/08/2007 |
| 7211395 | Serum albumin binding moieties Compositions comprising non-naturally occurring serum albumin binding moieties are described, together with methods of use thereof, e.g., for detecting or isolating serum albumin molecules in a solution, for blood circulation imaging, and for linking therapeutics or... | 05/01/2007 |
| 7208580 | Atomic structure of the hemalbumin complex and its use in designing therapeutic compounds A high resolution structure of the hemalbumin binding complex is provided which includes the detailed atomic coordinates which reflect the binding site and the binding characteristics of the structure. This high resolution structure can be used in methods of determi... | 04/24/2007 |
| 7186399 | Methods for targeted drug delivery A method for ligand-based binding of lipid encapsulated particles to molecular epitopes on a surface in vivo or in vitro comprises sequentially administering (a) a site specific ligand activated with a biotin activating agent; (b) an avidin activating agent; and (c)... | 03/06/2007 |
| 7182962 | Immunostimulator for animals and humans, and method of preventing animal and human infectious diseases and cancer The goal of the present invention is to provide substances to prevent diseases by activating inherently possessed functions, for cultured fishes and shellfishes and livestock with tendency of decreased immune function due to densely populated breeding environment, a... | 02/27/2007 |
| 7166577 | Albumin having enhanced antimicrobial activity The present invention provides a nitrosylated albumin variant wherein one or more amino acid residues of constituent amino acid sequences are substituted, or a different amino acid residue is inserted into a part of the constituent amino acid sequences. The albumin ... | 01/23/2007 |
| 7163805 | Human serum albumin-TIMP2 fusion protein, a polynucleotide encoding the same and a method of producing the human serum albumin-TIMP2 fusion protein The present invention provides a human serum albumin-TIMP2 fusion protein having the amino acid sequence set forth in SEQ ID NO. 10, a polynucleotide encoding the same and a vector comprising the polynucleotide, a host cell transformed with the vector, a method for ... | 01/16/2007 |
| 7163918 | Iodothyronine compositions The present invention relates to compositions comprising thyroxine (T4) and triiodothyronine (T3). More specifically, the invention relates to thyroxine (T4) and triiodothyronine (T3) compositions that include a peptide carrier and thyroxine (T4) and triiodothyronin... | 01/16/2007 |
| 7157616 | Method of selecting non-diabetogenic milk or milk products and milk or milk products so selected The invention is based on the discovery that certain variants of β-casein may induce Type-1 diabetes in susceptible individuals while other variants do not. The invention consists of the selection of non-diabetogenic milk producing cows and recovering and processin... | 01/02/2007 |
| 7151163 | Antiviral agents for the treatment, control and prevention of infections by coronaviruses The invention provides compositions and methods that are useful for preventing and treating a coronavirus infection in a subject. More specifically, the invention provides peptides and conjugates and pharmaceutical compositions containing those peptides and conjugat... | 12/19/2006 |
| 7141547 | Albumin fusion proteins comprising GLP-1 polypeptides The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic ac... | 11/28/2006 |
| 7129210 | Tissue adhesive sealant A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive with the aldehyde cross-links to form a seal. The sealant is well suited... | 10/31/2006 |
| 7115583 | Microbubble compositions and methods for oligonucleotide delivery The invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic agents. The methods and composition of the invention can be used with several therapeutic agents and can achieve site specific delivery of a therapeutic or ... | 10/03/2006 |
| 7115573 | Prodrug compounds with an isoleucine The compounds of the invention are modified forms of therapeutic agents. A typical prodrug compound of the invention comprises a therapeutic agent, an oligopeptide having an isoleucine residue, a stabilizing group and, optionally, a linker group. The prodrug is clea... | 10/03/2006 |
| 7115383 | Assays for amphetamine and methamphetamine Methods, compositions and kits are disclosed. The compounds disclosed comprise an amphetamine moiety and a methamphetamine moiety linked together by a first linking group. A second linking group depends from the first linking group and comprises a functional group. ... | 10/03/2006 |
| 7112563 | Therapies using hemoproteins Herein it is shown that hemoproteins (e.g., Ascaris hemoglobin, myoglobin, flavohemoglobins) have NO-consuming and deoxygenase activities. The invention provides a method of reducing the concentration of oxygen and/or nitric oxide in a mammal. The method of t... | 09/26/2006 |
| 7105160 | Antibody-serum protein hybrids Hybrid proteins are described which comprise one or more antigen-binding antibody fragments covalently linked to one or more serum carrier proteins. The hybrid proteins can bind antigens, have a long half-life in vivo and can be used in medicine for therapy and diag... | 09/12/2006 |
