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| Number | Title | Issue Date |
| 7432355 | Apolipoprotein E stable folding intermediate and methods of use thereof The present invention provides isolated apolipoprotein E (apoE) stable folding intermediates. The invention further provides methods for identifying compounds that alter the structure or level or activity of an apoE stable folding intermediate, as well as methods of... | 10/07/2008 |
| 7368293 | Liver enriched transcription factor HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes (Costa et al., 1989; Costa et al., 1990; Leff et al., 1989). We have pur... | 05/06/2008 |
| 7285638 | Method of obtaining biologically active collagen from skins of the salmonidae fish The method of obtaining collagen as above, is characterized by this, that the process of cleaning the skins is done manually using tools made of natural materials such as glass and wood to remove from the skins scales, skills and meat tissue so prepared raw material... | 10/23/2007 |
| 7157004 | Freeze drying for gas chromatography stationary phase deposition The present disclosure relates to methods for deposition of gas chromatography (GC) stationary phases into chromatography columns, for example gas chromatography columns. A chromatographic medium is dissolved or suspended in a solvent to form a composition. The comp... | 01/02/2007 |
| 7144855 | Protein complex from ion-exchange chromatography for treatment of bacterial infections The present invention relates to the use of alpha-lactalbumin in the preparation of preparations to be used in therapeutic or prophylactic treatment and/or for diagnostic use for infections, preferably of the respiratory tract, caused by bacteria, in particular S... | 12/05/2006 |
| 7026445 | Human SDF-5 protein and compositions Purified human SDF-5 proteins and processes for producing them are disclosed. DNA molecules encoding the human SDF-5 proteins are also disclosed. The proteins may be used in regulating the binding of Wnt genes to their receptor. In preferred embodiments, the protein... | 04/11/2006 |
| 7026453 | Method of protein purification Purification methods are provided for proteins and peptides, employing silicon carbide to bind the proteins or peptides. The methods may also be used to recover and purify recombinantly expressed proteins sequestered in inclusion bodies. The method for purifying a p... | 04/11/2006 |
| 6921537 | Preparation and uses of los-depleted outer membrane proteins of gram-negative cocci Described herein is a method for removing toxic lipooligosaccharide (LOS) from outer membranes of Gram-negative cocci, such as Neisseria meningitidis. LOS-depleted outer membranes and LOS-depleted soluble outer membrane proteins can be prepared, which are abl... | 07/26/2005 |
| 6884771 | Angiotensin converting enzyme homolog and uses therefor The present invention relates to the discovery of novel genes encoding an angiotensin converting enzyme, Angiotensin Converting Enzyme-2 (ACE-2). The invention provides therapeutics, prognostic and diagnostics methods for treating blood pressure related disorders as... | 04/26/2005 |
| 6849593 | Bifidogenic peptides Pepetides having bifidogenic properties are obtainable by the process of adding proteases to cow'milk or human milk, followed by incubation, centrifugation, acidification, purification by reverse phase HPLC and cation-exchange HPLC, culturing Bifidobacterium bifi... | 02/01/2005 |
| 6830917 | Method of isolation and purification of trypsin from pronase protease and use thereof The present invention is directed to methods of isolation and purification of Streptomyces griseus trypsin (SGT) from PRONASE protease in a single affinity chromatography step and uses of the purified SGT. ... | 12/14/2004 |
| 6800449 | High throughput functional proteomics A method is disclosed which provides a high throughput method for assigning plausible functions to unknown sequence entries in a particular database. The method was used herein to identify lectin proteins which can be found in specific tissues of the rice plant.... | 10/05/2004 |
| 6599874 | Protein complex from ion-exchange chromatography of casein for treatment of bacterial infections Antibacterial protein complexes designated as Anti-adhesive Lactalbumin Like Protein (ALLP) are obtained by ion-exchange chromatography of casein and alpha-lactalbumin. Casein isolated from human milk by acid precipitation is subjected to ion-exchange chr... | 07/29/2003 |
| 6579849 | Antibiotic peptides from bovine milk A peptide having the amino acid sequence H2 N--X1 --R--X3 --X2 --COOH (formula I) wherein X1 is either zero or X1 and/or X2 are a residue representing at least five amino acid residues (s... | 06/17/2003 |
| 6555659 | Process for isolating glycomacropeptide from dairy products with a phenylalanine impurity of 0.5% w/w The present invention is related to a method for the purification of glycomacropeptide (GMP) with an amino acid composition containing no greater that 0.5% (w/w) phenylalanine, comprising the steps of contacting a GMP-containing feedstock with a first ani... | 04/29/2003 |
| 6506732 | Enzymatic hydrolysate of milk proteins The present invention relates to a mixture of soluble hydrophobic peptides of an enzymatic hydrolysate of milk having skin hydrating properties and percutaneous absorption levels of 4 to 5%. The mixture also exhibits wound healing properties but does not ... | 01/14/2003 |
| 6500672 | Liver enriched transcription factor HNF-4 (hepatocyte nuclear factor 4) is a protein enriched in liver extracts that binds to sites required for the transcription of the transthyretin (TTR) and apolipoprotein CIII (apoCIII) genes (Costa et al., 1989; Costa et al., 1990; Leff et al., 1989). ... | 12/31/2002 |
| 6462181 | Process for preparing a kappa-caseino glycomacropeptide or a derivative thereof Improved process for preparing a kappa-caseino glycomacropeptide which comprises adjusting the pH of a solution of a milk starting material to below 4, cold ultrafiltration and concentration of the starting material on a spiral filter. This process is usa... | 10/08/2002 |
| 6432407 | Antigenic protein originating in malassezia A substantially pure, isolated, antigenic protein from fungi of the genus Malassezia, characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergoses; an antigenic fragment derived from the antigenic prot... | 08/13/2002 |
| 6355253 | Preparation and uses of LOS-depleted outer membrane proteins of gram-negative cocci Described herein is a method for removing toxic lipooligosaccharide (LOS) from outer membranes of Gram-negative cocci, such as Neisseria meningitidis. LOS-depleted outer membranes and LOS-depleted soluble outer membrane proteins can be prepared, which are... | 03/12/2002 |
| 6183803 | Method for processing milk The present invention relates to methods for separating casein from milk, and for separating from milk proteins that can be associated or entrained within casein micelles, by contacting the milk with a chelating agent to disrupt the casein micelles and re... | 02/06/2001 |
| 6150506 | Modified hemoglobin-like compounds and methods of purifying same The present invention relates to modified hemoglobin-like polypeptides containing multiple dialpha (or dibeta) domains. The present invention also relates to multimeric hemoglobin-like proteins comprising covalently joined hemoglobin-like moieties. Anothe... | 11/21/2000 |
| 6121421 | Methods for isolating recombinant ଲ-casein The invention provides a method for isolating a protein, specifically ଲ-casein, recombinantly produced in cells that have been genetically engineered to produce the protein. The method involves forming a paste, homogenate or lysate of the cells foll... | 09/19/2000 |
| 6080844 | Process for the recovery and purification of a recombinant protein from a cell The present invention involves a process of purifying and recovering a recombinant protein from a suspension of cells. The process of the present invention involves extracting a recombinant protein from a concentrated suspension of cells using a water-mis... | 06/27/2000 |
| 6063902 | Ectoparasite histamine releasing factor, genes and uses thereof The present invention relates to ectoparasite histamine releasing factor (HRF) proteins; to ectoparasite HRF nucleic acid molecules, including those that encode such HRF proteins; to antibodies raised against such HRF proteins; and to compounds that inhib... | 05/16/2000 |
| 6010844 | Methods of preparing and recovering proteins There is disclosed the preparation and recovery of proteins, in particular of enzymes, by controlled proteolytic cleavage of pro-proteins, in particular pro-enzymes, in a single method step, wherein a pro-protein-containing solution is contacted with a pr... | 01/04/2000 |
| 5990081 | Purified APO A and APO E compounds and methods for using them A substantially endotoxin-free ApoA or ApoE is produced by recombinant DNA technique, suitably in E. coli. Medicaments and methods for treatment of atherosclerosis or cardiovascular diseases employ ApoA or ApoE purified by a process comprising contacting ... | 11/23/1999 |
| 5968901 | Antibacterial composition The present invention relates to a use of casein derived from milks, preferably human milk, and porcine milk, for the preparation of a substrate for the prophylactic and/or therapeutic treatment of infections of the respiratory tract caused by S. pneumoni... | 10/19/1999 |
| 5925736 | Collagen-based methods and formulations for the treatment of arthritis The invention provides novel methods and compositions for the treatment of immune system-mediated arthritis, including rheumatoid arthritis. The subject compositions comprise one or more different types of collagen or collagen derivatives and a mucosa bin... | 07/20/1999 |
| 5883227 | Multiple sclerosis associated polypeptide The present invention relates to the diagnosis of multiple sclerosis. More specifically, this invention relates to an assay for detecting antigen(s) associated with multiple sclerosis. The present invention also relates to the generation of hybridomas whi... | 03/16/1999 |
| 5834596 | Process for purifying ApoA or ApoE A process for purifying apolipoprotein A (ApoA) or apolipoprotein E (ApoE), or variants or mixtures thereof, comprises contacting a first aqueous solution comprising ApoA or ApoE and endotoxins with a matrix comprising an immobilized compound with an end ... | 11/10/1998 |
| 5798446 | Method of extracting proteins utilizable in foodstuff from a protein-containing substance In the method described, a protein-containing substance is first taken up in an alkaline solvent to give a solution. Insoluble constituents of the substance are separated off, the solution is neutralized and desalinated, and then the proteins contained in... | 08/25/1998 |
| 5780593 | Method of isolating biomolecules by ion exchange A method of isolating a biomolecule from a medium containing biomolecules by ion exchange wherein the ion exchange material consists of a material having ion exchanging groups which can be transformed from a charged form to an uncharged form; the eluant c... | 07/14/1998 |
| 5739407 | Human ଲ-casein, process for producing it and use thereof The present invention relates to a DNA sequence encoding the human milk protein ଲ-casein or an analogue or variant thereof which has either the calcium binding activity of human ଲ-casein, or opioid activity, or angiotensin converting enzyme (A... | 04/14/1998 |
| 5703212 | Preventive for circulatory diseases A preventive for circulatory diseases which can prevent the onset of circulatory diseases, particularly cerebral stroke, without causing adverse effects such as blood-pressure fluctuation. The preventive contains as the active ingredient a low-molecular-w... | 12/30/1997 |
| 5683984 | Enteral tube feeding composition with a native micellar casein protein component An enteral composition of protein, glucides, lipids and minerals, which is suitable for tube feeding, employs native micellar casein as the protein. The composition is prepared by obtaining native micellar casein and combining it with the glucides, lipids... | 11/04/1997 |
| 5681586 | Enzyme-modified soy and soy/casein combination healing compositions A pharmaceutical composition comprising an improved modified protein sol is used for treating and enhancing the healing of arthritis and cutaneous acne. Prior to being modified, a protein is solubilized and neutralized by an alkali solution containing a m... | 10/28/1997 |
| 5591443 | Synergistic insecticide composition The method of making a neurotoxic insecticide which comprises: 1. Extracting a relatively heat stable, lipophilic, calcium linked, free sufhydryl, proteinaceous extract from casein, in particular the kappa casein thereof, or a casein containing material, such ... | 01/07/1997 |
| 5473050 | Denatured bovine serum albumin milk products and method therefor A method of producing denatured bovine serum albumin (BSA) milk products is disclosed which provides a container for containing the milk products and a source of heating the container for a period of time and within a certain temperature range sufficient ... | 12/05/1995 |
| 5432265 | Process for the continuous removal of products from high pressure systems The continuous removal of solid products from a high-pressure system is achieved by operating a high-pressure pump in reverse to gradually reduce pressure at the exit line to atmospheric pressure. This process allows solid products to exit the system whil... | 07/11/1995 |
