Class 530/328 - 8 to 10 amino acid residues in defined sequence

Subclass of Class 530 - Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Definition: Compounds comprising from 8 to 10 amino acid residues of
No. of patents: 2200
Last issue date: 05/29/2012

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Number	Title	Issue Date
8188220	Methods and compositions related to targeting wounds, regenerating tissue, and tumors Disclosed are compositions and methods useful for targeting regenerating tissue, wounds, and tumors. The compositions and methods are based on peptide sequences that selectively bind to and home to regenerating tissue, wound sites, and tumors in animals. The disclos...	05/29/2012
8188221	Peptide homing to brain tumors The present invention relates to a peptide, which specifically homes to the intracranial, early stage astrocytoma model that grows as islets and harbors co-opted tumor vessels in the brain. The peptide finds its use in targeted delivery of therapeutic substances to ...	05/29/2012
8178651	Somatostatin-dopamine chimeric analogs Disclosed is a series of somatostatin-dopamine chimeric analogs which retain both somatostatin and dopamine activity in vivo. An example is: 6-n-propyl-8β-ergolinglmethylthioacetyl-D-Phe-c(Cys-Tyr-D-Trp-Lys-Abu-Cys)-Thr-NH2. ...	05/15/2012
8168585	Purification of peptides from colostrum The invention relates to the purification of peptides from colostrum. The method involves the addition of an alcohol such as methanol or ethanol to the mixture in order to form an alcohol phase rich in the peptides, and a precipitate. The peptide-rich alcohol phase ...	05/01/2012
8153599	Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension The present invention relates to peptides which are highly biologically and pharmacologically active as therapeutic drug for the treatment of diseases related to hypertension, especially in medical interventions involving dilatation and remodeling of arterial blood ...	04/10/2012
8138140	Self-assembling peptide amphiphiles and related methods for growth factor delivery Amphiphilic peptide compounds comprising one or more epitope sequences for binding interaction with one or more corresponding growth factors, micellar assemblies of such compounds and related methods of use. ...	03/20/2012
8110554	Peptides whose uptake by cells is controllable A generic structure for the peptides of the present invention includes A-X-B-C, where C is a cargo moiety, the B portion includes basic amino acids, X is a cleavable linker sequence, and the A portion includes acidic amino acids. The intact structure is not signific...	02/07/2012
8101580	Therapeutic agent for irritable bowel syndrome It was shown that bombesin 2 (BB2) receptor antagonists typified by RC-3095 are therapeutic agents for irritable bowel syndrome (IBS), and show excellent efficacy in treating both an abdominal symptom and bowel movement disorder. Thus, the present invention provides...	01/24/2012
8080634	Immunogenic epitope for immunotherapy The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-helper cell peptide ...	12/20/2011
8076452	Streptavidin-binding peptide The invention relates to novel streptavidin binding peptides. ...	12/13/2011
8076453	Kinin Breceptor peptide agonists and uses thereof The present invention provides for novel kinin B1 receptors peptide agonists of formula (I) having very good to excellent affinities and selectivity for the B1 receptor, in vitro and in vivo increased resistance to enzymatic degradation, superior pharmaco...	12/13/2011
8071552	Peptides and peptidomimetics binding to CD23 The present invention describes compounds comprising new and useful peptides and peptidomimetics that can bind to CD23. They are capable of reducing inflammatory responses associated with auto-immune diseases, chronic inflammatory diseases, allergies and other infla...	12/06/2011
8067376	Pharmaceutical compositions for transdermal delivery The present invention relates to a pharmaceutical composition for transdermal administration comprising a conjugate of methotrexate and PTD (protein transduction domain). In accordance with the present invention, the methotrexate, which is widely used for the treatm...	11/29/2011
8067535	Identification of gene sequences and proteins involved in vaccinia virus dominant T cell epitopes The present invention relates to the identification of gene sequences and proteins involved in vaccinia virus dominant T cell epitopes. Three vaccinia virus CD8+ T cell epitopes restricted by the most common human M.C. class I allele, HLA-A0201, were iden...	11/29/2011
8067536	Kinase and phosphatase assays Compositions, methods, and kits for detecting and monitoring kinase, phosphatase and protein post-translational modification activity are described. The compositions typically include a peptide, a detectable moiety, and a protease cleavage site. Modification of a pe...	11/29/2011
8067378	Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells The embodiments include methods of treating conditions requiring removal or destruction of cellular elements, such as benign or malignant tumors in humans, using compounds based on small peptides. The method includes, but is not limited to, administering the compoun...	11/29/2011
8053557	SPARC-derived tumor rejection antigenic peptides and medicaments comprising the same It is an objective of the present invention to identify SPARC protein-derived peptides that are able to induce human killer T cells and helper T cells having cytotoxic activity to tumors, and to provide a means for carrying out a tumor immunotherapy of patients with...	11/08/2011
8053556	Glypican-3 (GPC3)-derived tumor rejection antigenic peptides useful for HLA-A2-positive patients and pharmaceutical comprising the same It is an object of the present invention to identify a glypican-3-derived peptide which can bind to HLA-A2 and activate human killer T cells, so as to provide a means for carrying out an immunotherapy which is able to target approximately 40% of Japanese patients su...	11/08/2011
8039585	Therapeutic administration of the scrambled anti-angiogenic peptide C16Y Unregulated angiogenesis is associated with a variety of pathological conditions. Tumor growth and metastasis is dependent on the development of new blood vessels. The development of new blood vessels in the eye, or ocular neovascularization, has been implicated in ...	10/18/2011
8030280	Melanoma antigens and their use in diagnostic and therapeutic methods The present invention provides an isolated or purified immunogenic peptide comprising 8-15 contiguous amino acids of gp100 (SEQ ID NO: 121) and related nucleic acids, expression vectors, host cells, populations of cells, and methods of use. The invention further pro...	10/04/2011
8026208	Peptide tyrosinase inhibitors and uses thereof Disclosed are peptides, which inhibit the enzymatic activity of tyrosinase, as well as formulations and methods for their use in the reduction of skin pigmentation, and methods of administering the inhibitory peptides in a topical formulation. The peptides are chara...	09/27/2011
8026218	Bifunctional analgesic compounds for opioid receptor agonists and neurokinin-1 receptor antagonists The present invention provides a novel chimeric compound comprising an agonist opioid receptor binding moiety at its N-terminus and an antagonist neurokinin-1 (NK1) receptor binding moiety at its C-terminus for producing analgesia, a pharmaceutical composition compr...	09/27/2011
8017729	Nanographite structure/metal nanoparticle composite The present invention makes it possible to efficiently recognize carbon nanotubes, carbon nanohorns or modifiers thereof and to support functional compounds by fusing the ability of ferritin molecules capable of forming nanoparticles of inorganic metal atoms or inor...	09/13/2011
8017578	Orally active peptides that prevent cell damage and death This invention provides an ADNF polypeptide comprising an active core site, the active core site comprising at least one D-amino acid. The invention also provides a pharmaceutical composition comprising an ADNF polypeptide comprising an active core site, the active ...	09/13/2011
8013117	Solution-phase synthesis of leuprolide and its intermediates A process for producing a nonapeptide leuprolide and an intermediate N-protected oligopetides, wherein at least one peptide bond of the compound is formed by reacting an activated carboxylic acid and an amine component in a continuous flow. ...	09/06/2011
8008260	Methods of protecting against apoptosis using lipopeptides The use of lipopeptides as inducers of NF-κB for the protection of mammals from the effects of apoptosis is described. ...	08/30/2011
7999071	Human cytotoxic T-lymphoctye epitope and its agonist eptiope from the non-variable number of tandem repeat sequence of MUC-1 Novel MUC-1 epitopes outside the VNTR region are identified. In addition, the first agonist epitope of MUC-1 is described. The employment of agonist epitopes in peptide, protein and vector-based vaccine may well aid in the development of effective vaccines for a ran...	08/16/2011
7994279	Altered peptide ligands of GAD65 Modified GAD65 compositions antagonize the activities of islet-specific T cells that contribute to the progression of one or more autoimmune disorders. The compositions are also antagonistic in humanized mice that express human HLA alleles associated with increased-...	08/09/2011
7964701	Alpha-fetoprotein peptides The invention relates to compounds that include peptides that inhibit estrogen receptor dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwa...	06/21/2011
7960348	Metastin derivatives and use thereof The present invention provides stable metastin derivatives having excellent biological activities (a cancer metastasis suppressing activity, a cancer growth suppressing activity, a gonadotropic hormone secretion stimulating activity, sex hormone secretion stimulatin...	06/14/2011
7960507	Tumor associated antigen peptides and use of same as anti-tumor vaccines The present invention relates to tumor associated antigen (TAA) peptides and to use of same, of polynucleotides encoding same and of cells presenting same as anti-tumor vaccines. More particularly, the present invention relates to tumor associated antigen peptides d...	06/14/2011
7951781	Methods and compositions related to PLUNC surfactant polypeptides Embodiments include compositions and methods for lower the surface tension of a liquid-air interface by contacting such interface with all or part of a PLUNC polypeptide. ...	05/31/2011
7939627	Peptides comprising an epitope of the wilms tumor gene product A compound of formula (1): wherein X is a tyrosine residue or a methionine residue; Y and Z each are a single bond; R1 is a hydrogen atom; R2 is a hydroxy group; R3 is a hydrogen atom, alkyl g...	05/10/2011
7932229	Compositions and methods for the control of mammary cell number The present invention provides new methods and uses of peptides in effecting a reduction in mammary cell number. The discovery that these peptides reduce mammary cell number further enables the use of these peptides in the treatment of cancer where the peptides can ...	04/26/2011
7928190	Methods and compositions for tumor vaccination and therapy The present invention relates to peptide vaccines, pharmaceutical compositions thereof, and associated methodologies that promote the immune-mediated regression of tumors expressing an onconeural antigen, e.g. a cdr-2 antigen, HuD antigen. The cancer peptide vaccine...	04/19/2011
7919581	Bi-dentate compounds as kinase inhibitors The present invention provides compound having the general structure A or pharmaceutically acceptable salts thereof: Het-L-P (A) wherein Het is an aromatic moiety comprising a heterocyclic structure mimicking ATP, P is a docking site derived...	04/05/2011
7915380	Compositions, systems and methods for the diagnosis, prevention and treatment of disorders associated with azetidine-2-carboxylic acid Methods and systems for detecting azetidine-2-carboxylic acid (Aze) in food consumable by humans and animals are provided. Also provided are methods and systems for inactivating Aze in food and byproducts, as well as other methods for the diagnosis, prevention, and ...	03/29/2011
7902330	Protein kinase inhibitors and methods for identifying same Inhibitors of protein kinase C (PKC)α, PKCδ and PKCζ are provided which are selective for those PKC isotypes. Combinatorial libraries for identifying protein kinases are also provided, as are methods of identifying protein kinases using those libraries. Additiona...	03/08/2011
7902331	Forisomes, method for their isolation, and their use as a molecular working machine A protein body derivable from Fabaceae has a reversible, anisotropic contractability such that the protein body becomes thicker perpendicular to a longitudinal axis of the protein body and shorter along the longitudinal axis of the protein body when increasing a cal...	03/08/2011
7851591	Cancer immunotherapy and diagnosis using universal tumor associated antigens, including hTERT The invention provides methods for conducting cancer immunotherapy and diagnosis using universal tumor associated antigens, such as the telomerase catalytic subunit (hTERT), and methods for identifying and characterizing universal tumor associated antigens. ...	12/14/2010

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Class 530/328 - 8 to 10 amino acid residues in defined sequence