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Class 530/320 - Bacitracin; related peptides


Subclass of Class 530 - Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Definition: Peptides containing at least half the amino acid sequence
No. of patents: 32
Last issue date: 12/07/2010


NumberTitleIssue Date
7847062Pharmacokinetic modulation and compositions for modified FN3 polypeptides
The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure...
12/07/2010
7279458Cross-linked glycopeptide-cephalosporin antibiotics
This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacter...
10/09/2007
7109323Formulation of boronic acid compounds
The invention relates to the formulation of pharmaceutical compounds. More particularly, the invention provides stable, pharmaceutically acceptable compositions prepared from boronic acid compounds and methods for preparing the compositions. The invention also provi...
09/19/2006
7067482Cross-linked glycopeptide-cephalosporin antibiotics
This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacter...
06/27/2006
RE39071Anhydro-and isomer-a-21978c cyclic peptides
Two new groups of A-21978C cyclic peptides, anhydro- and isomer-A21978C peptide derivatives, have antibacterial activity and are useful as intermediates. The two groups are prepared via transpeptidation of the parent cyclic peptides. Pharmaceutical formulations cont...
04/18/2006
6913756Monoclonal antibodies specific for anthrax and peptides derived from the antibodies thereof
The present invention provides monoclonal antibodies which are highly specific for Bacillus spores. Also provided are peptides derived from those monoclonal antibodies. Both the antibodies and peptides are highly specific and can discriminate between spores of poten...
07/05/2005
6849714Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
A method of synthesizing a modified therapeutic peptide capable of forming a peptidase-stabilized therapeutic peptide conjugate, the peptide having between 3 and 50 amino acids, is k. In a first step of the method, a therapeutic peptide having a carboxy terminal ami...
02/01/2005
6692919Activated forms of notch and methods based thereon
The present invention is directed to methods for detecting or measuring Notch activation by observing or measuring the appearance of Notch on the cell surface or by observing or measuring Notch cleavage products that are indicative of Notch activation. Th...
02/17/2004
6686443Chemical reagents for formation of disulfide bonds in peptides
This invention pertains to the discovery of a class of reagents that effectively form intramolecular disulfide bonds in peptides. Intermolecular disulfide linkage formation is low or essentially non-existent. In addition, preferred reagents of this invent...
02/03/2004
6660267Prevention and treatment of sepsis
Compositions and methods are described for preventing and treating sepsis in humans and animals. Surgical patients, low birth weight infants, and burn and trauma victims can be treated prophylactically. Methods for treating acute infections are provided w...
12/09/2003
6562785Method for overcoming bacterial antibiotic resistance
The present invention is drawn to methods of killing bacteria, including antibiotic resistant bacteria, by contacting said bacteria with a membrane permeabilizing compound or combination of compounds and a membrane impermeant toxic agent or combination of...
05/13/2003
6488932Method for treating cancer by administering MAGE-derived peptides
The invention involves the reception of particular nonapeptides by HLA molecules. The nonapeptides are derived from expression products of the MAGE gene family. The resulting complexes are identified by cytolytic T cells. Such recognition may be used in d...
12/03/2002
6355788Follistatin-related protein zfsta2
The present invention relates to polynucleotide and polypeptide molecules for zfsta2, a novel member of the follistatin family. The polypeptides, and polynucleotides encoding them are useful for binding to members of the TGF-ଲ family and mediating c...
03/12/2002
6241965Somatostatin derivatives and their radiolabelled products
This invention relates to therapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for producing labelled radiodiagnostic agents. Specifically, the invention relates to linear peptide derivatives and analogs of somatostatin, a...
06/05/2001
6214793Method of treating tumors with thiodepsipeptide isolated from a marine actinomycete
The present invention is directed to a novel depsipeptide has been isolated from a new marine strain L-13-ACM2-092 belonging to the family Micromonosporaceae. Its production by aerobic fermentation under controlled conditions of the strain, and the isolat...
04/10/2001
6103493Streptavidin muteins
The invention concerns a polypeptide selected from muteins of streptavidin which is characterized in that it (a) contains at least one mutation in the region of the amino acid positions 44 to 53 with reference to wild type-(wt)-streptavidin and (b) has a ...
08/15/2000
6063612Antiviral reagents based on RNA-binding proteins
The present invention describes the generation of site-directed RNA cleaving agents. These agents consist of RNA-binding proteins, or polypeptides derived thereof, which are modified to contain a moiety capable of cleaving RNA backbones. Alternatively, th...
05/16/2000
6063758Substance P-Saporin (SP-SAP) conjugates and methods of use thereof
This invention provides a conjugate comprising Substance P, and analogs thereof, and Saporin. This invention provides a method of reducing the perception of pain by a subject comprising administering to the subject an effective dose of the pharmaceutical ...
05/16/2000
6001967Herpes virus proteinase and method of assaying
A herpes virus proteinase has been found to be encoded by a member of a family of four nested genes in simian cytomegalovirus. Another member of the nested genes encodes the assembly protein precursor, which is a substrate for the proteinase. Homologous g...
12/14/1999
5968513Method of promoting hematopoiesis using derivatives of human chorionic gonadotropin
The present invention relates to methods of treating or preventing diseases or disorders associated with hematopoietic deficiency by administration of human chorionic gonadotropin, ଲ-human chorionic gonadotropin or a peptide containing a sequence of...
10/19/1999
5750135Stabilized feed additive and process for the preparation thereof
The invention relates to a stabilized feed additive, more particularly containing zinc bacitracin, and processes for the preparation thereof....
05/12/1998
5344765DNA encoding polypeptides with activity against gram-positive and gram-negative bacteria
The invention relates to cecropin-like polypeptides with a variety of C-terminus modifications. Conversion of the terminal carboxy group to a homoserine extended neutral, negatively charged or positively charged form results in the polypeptides of the inv...
09/06/1994
5116817LHRH preparations for intranasal administration
The present invention relates to a novel nasal composition comprising a nona- or decapeptide having LHRH agonist or antagonist activity and a surfactant which is a bile acid or a pharmaceutically acceptable salt thereof in a buffered aqueous solution....
05/26/1992
5002932Antiviral pharmaceutical compositions and method of treating herpes
Disclosed herein is a combination of bacitracin and acyclovir or equivalent derivatives thereof. The combination, as well as bacitracin itself, are useful for treating herpes viral infections....
03/26/1991
4600705Gonadoliberin derivatives containing a ଲ-aspartyl group, a process for the preparation thereof and pharmaceutical preparations containing them
The invention relates to novel gonadoliberine derivatives of the general formula (I) ##STR1## wherein X represents an --O--R group wherein R is a benzyl group or a C1-4 alkyl group, an ##STR2## group wherein R1 and R2 independen...
07/15/1986
4461725Protein compounds
The present invention is directed to certain multiprotein compounds and methods for using such compounds in the treatment of psoriasis, arthritis, erythropoietic protoporphyria, and scar tissue and wounds. These multiprotein compounds include beta-lactogl...
07/24/1984
4237045N-substituted cyclopeptide derivatives and preparation thereof
The N-substituted cyclopeptide derivatives of formula I ##STR1## in which R1 is lower alkyl, R2 is lower alkyl or cyclo(lower)alkyl, R3 is a neutral amino acid side chain and Y is a peptide residue having three to nin...
12/02/1980
4218437Animal feeds containing a mixture of virginiamycin, zinc bacitracin or flavophospholipol and proteolytic enzymes
Animal feeds based on carbohydrates, protein and fats containing from 5 to 150 ppm of one of the antibiotics Virginiamycin, zinc Bacitracin or flavophospholipol and a content of proteolytic enzymes in such an amount that the enzymatic activity is from 0.0...
08/19/1980
4164572Zinc bacitracin composition for use as a feed supplement and method for making the same
A zinc bacitracin composition for use as a feed supplement which possesses improved stability to heat, mechanical mixing and moisture when used in substantially dry animal feeds. Zinc bacitracin is precipitated by the addition of zinc cations, as in the r...
08/14/1979
4101539Bacitracin recovery process
A process for the recovery of bacitracin from a fermented beer containing it comprising the steps of: A. screening the fermented beer through a 100-150 mesh screen, B. adjusting the pH of the fermented beer to about 7.5 to about 8.7, C. ultrafiltering the fermented...
07/18/1978
3966699Reduced bacitracin
Reduced bacitracin and pharmaceutically acceptable salts thereof obtained by treating bacitracin with a reducing agent. The resulting product has improved stability....
06/29/1976
3937694Process for the recovery of zinc bacitracin free from zinc hydroxide
A process for the recovery of bacitracin in the form of a zinc complex wherein the pH is raised to precipitate the zinc bacitracin complex. The zinc bacitracin complex is precipitated in the presence of ammonium ion which complexes the excess zinc and mai...
02/10/1976
 
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