Class 530/319 - Polymyxin; related peptides

Subclass of Class 530 - Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
Definition: Peptides containing at least half the amino acid residues
No. of patents: 24
Last issue date: 02/01/2011

Number	Title	Issue Date
7879798	Composition for indolent wound healing and methods of use therefor A topical ointment is described for use in the treatment of indolent wounds composed of fat-soluble vitamins, namely, vitamin A, vitamin D, vitamin E, and a subantimicrobial amount of polypeptide antibiotic, which, in turn, acts as a proteinase inhibitor. The active...	02/01/2011
7435716	Compounds pharmaceutical compositions and methods for treatment of bacteremia and/or septicemia Novel conjugates of bacterial outer membrane binding peptides, preferably having bacterial sensitization activity, and immune cells chemotactic peptides, and pharmaceutical compositions containing same useful in the treatment of bacteremia and/or septicemia followin...	10/14/2008
7033580	Hair-growing agent Disclosed is a safe and effective hair-growing agent comprising a protein kinase C-specific inhibitor. ...	04/25/2006
6916784	Cyclic peptide antifungal agents and process for preparation thereof Provided are compounds of the formula (1): wherein R′ is hydrogen, methyl or NH2C(O)CH2—; R″ and R′″ are independently methyl or hydrogen; ...	07/12/2005
6913756	Monoclonal antibodies specific for anthrax and peptides derived from the antibodies thereof The present invention provides monoclonal antibodies which are highly specific for Bacillus spores. Also provided are peptides derived from those monoclonal antibodies. Both the antibodies and peptides are highly specific and can discriminate between spores of poten...	07/05/2005
6911455	Methods for preparing pharmaceutical formulations The invention relates to pharmaceutical formulations and methods for preparing pharmaceutical formulations of histamine releasers. The present invention provides methods for determining the concentration of physiologically acceptable excipients for use in the formul...	06/28/2005
6660267	Prevention and treatment of sepsis Compositions and methods are described for preventing and treating sepsis in humans and animals. Surgical patients, low birth weight infants, and burn and trauma victims can be treated prophylactically. Methods for treating acute infections are provided w...	12/09/2003
6586002	Enhanced circulation effector composition and method A liposome composition comprising small, surface-bound effector molecules is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal e...	07/01/2003
6506370	Hair-growing agent Disclosed is a safe and effective hair-growing agent comprising a protein kinase C-specific inhibitor....	01/14/2003
6380356	Multivalent polymyxin antibiotics Disclosed are multibinding compounds which are antibiotics effective against bacterial infections, in particular, Gram-negative bacterial infections. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one o...	04/30/2002
6326353	Enhanced circulation effector composition and method A liposome composition comprising small, surface-bound effector molecules is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal e...	12/04/2001
6214793	Method of treating tumors with thiodepsipeptide isolated from a marine actinomycete The present invention is directed to a novel depsipeptide has been isolated from a new marine strain L-13-ACM2-092 belonging to the family Micromonosporaceae. Its production by aerobic fermentation under controlled conditions of the strain, and the isolat...	04/10/2001
6180134	Enhanced ciruclation effector composition and method A liposome composition comprising small, surface-bound effector molecules is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal e...	01/30/2001
6140306	Method of treating gram-negative bacterial infection by administration of bactericidal/permeability-increasing (BPI) protein product and antibiotic The present invention relates to methods and compositions for treating gram-negative bacterial infections, using BPI protein products. Co-treatment, or concurrent administration, of BPI protein product with an antibiotic in treatment of gram-negative bact...	10/31/2000
5834430	Potentiation of antibiotics The present invention is concerned with methods of potentiating an antibiotic. The invention also includes compositions of an antibiotic and a peptide having units of the formula: (a) (A)n wherein A is Lysine or Arginine and n is an integer with a ...	11/10/1998
5696083	Personal care composition containing pyrithione and polymyxin This invention relates to personal care compositions, and, more specifically, to a composition comprising a pyrithione salt or acid, polymyxin antibiotic, and a suitable carrier. The pyrithione plus the polymyxin provide antimicrobial efficacy to the pers...	12/09/1997
5545721	Conjugates for the prevention and treatment of sepsis Compositions and methods are described for preventing and treating sepsis in humans and other animals. Surgical patients, low birth weight infants, burn and trauma victims, as well as other individuals at risk can be treated prophylactically. Methods for ...	08/13/1996
5523288	Method of treating gram-negative bacterial infection by administration of bactericidal/permeability-increasing (BPI) protein product and antibiotic The present invention relates to methods and compositions for treating gram-negative bacterial infections, using BPI protein products. Co-treatment, or concurrent administration, of BPI protein product with an antibiotic in treatment of gram-negative bact...	06/04/1996
5510242	Method for using polymyxin-coated substrate for lipopolysaccharide detection An improved device is provided which may be used, e.g. for immunoassay of lipopolysaccharides or for removing LPS pyrogens from aqueous solutions, or for removing LPS endotoxins from wounds. Such device comprises, in combination, a substrate, e.g. plastic...	04/23/1996
5358933	Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock Novel peptides are disclosed which are based on the formula: R1 (Lys-Phe-Leu)n --R wherein n is an integer of from 1-10 and R and R1 are H or an amino acid residue or a fatty acid residue which are useful in the treatment of se...	10/25/1994
5177059	Polymyxin B conjugates Polymyxin B carrier conjugates, especially polymyxin B-dextran, are water soluble, have a greater half-life in the bloodstream and are significantly less toxic than native polymyxin B....	01/05/1993
5132288	Method for controlling Salmonella enteritidis in poultry In vitro results indicate that trimethoprim may be ineffective against S. enteritides. However, in vivo results show that trimethoprim alone and in combination with polymyxin B sulfate is effective on S. enteritidis infections in poultry....	07/21/1992
4870158	Polymyxin lipopolysaccharide antigen and associated method Antigens that produce antibodies specific for the lipopolysaccharide or endotoxin are produced and characterized. A method of producing the antigen is disclosed. These specific antibodies may be used as immunodiagnostic agents to detect the presence of an...	09/26/1989
4039519	Broad spectrum antibiotics and method The present invention relates to the new antibiotic polymyxine methyl tetracycline wide spectrum salts of the general formula in which m and n represent positive integers of less than 6, A= and B- represent mineral or organic anions, T re...	08/02/1977

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Class 530/319 - Polymyxin; related peptides