Quotables
"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 8158720 | Crosslinkable polymer compositions and associated methods Crosslinkable polymer compositions are provided that may be useful for, among other things, reducing, stopping, or diverting the flow of fluids in subterranean formations. The crosslinkable polymer compositions may comprise an aqueous fluid, a chitosan-reacting poly... | 04/17/2012 |
| 8153725 | Supports for oligomer synthesis Universal linkers, their facile processes of manufacture and methods of using the same are provided. ... | 04/10/2012 |
| 8058344 | Glycodendrimers having biological activity The present invention relates to new anionic glycodendrimers having new biological activity, processes for preparing them and their use in medicine including veterinary medicine. ... | 11/15/2011 |
| 7977427 | Method involving 1-benzotriazolyl carbonate esters of polymers The invention provides a method comprising the steps of (i) reacting a water-soluble and non-peptidic polymer having two or more terminal hydroxyl groups with di(1-benzotriazolyl)carbonate to form a water-soluble and non-peptidic polymer having two or more 1-benzotr... | 07/12/2011 |
| 7723432 | Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol) The invention provides a method for preparing a 1-benzotriazolylcarbonate ester of a water-soluble and non-peptidic polymer by reacting a terminal hydroxyl group of a water-soluble and non-peptidic polymer with di(1-benzotriazolyl)carbonate in the presence of an ami... | 05/25/2010 |
| 7544738 | Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol) The invention provides a method for preparing a 1-benzotriazolylcarbonate ester of a water-soluble and non-peptidic polymer by reacting a terminal hydroxyl group of a water-soluble and non-peptidic polymer with di(1-benzotriazolyl)carbonate in the presence of an ami... | 06/09/2009 |
| 7473734 | Michael addition compositions A functional composition is provided that comprises at least one multi-functional Michael acceptor, at least one multi-functional Michael donor, and at least one weakly basic catalyst. ... | 01/06/2009 |
| 7473733 | Cationic graft-copolymer for non-viral gene delivery vector A cationic graft-copolymer for a non-viral gene delivery vector comprising a unit derived from a cationic derivative of a water-soluble linear polymers having a hydroxyl groups, namely, a cationic polysaccharide of the following formula (1) [C6H7O2(OH)3-a (OX)a]x H2... | 01/06/2009 |
| 7416845 | pH dependent ion exchange material, solid substrate having the material immobilized on its surface, and method of isolating a nucleic acid using the material or the solid substrate Provided are a pH dependent ion exchange material having a carboxyl group, an amino group, and a polyethylene oxide moiety, which is used for isolating a nucleic acid, a solid substrate having the material immobilized on its surface, and a method of isolating a nucl... | 08/26/2008 |
| 7393503 | Emissive polymers and devices incorporating these polymers The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable pr... | 07/01/2008 |
| 7390497 | Poly(ester amide) filler blends for modulation of coating properties Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom. The PEA polymer blend is formed of a PEA polymer and a material capable of hydrogen bonding with the PEA. The PEA polymer blend can form a coating on an implantable device, ... | 06/24/2008 |
| 7385004 | Enhanced lubrication in polyolefin closure with polyolefin grafted cyclodextrin Thermoplastic polymer compositions in a closure can comprise a polymer, a modified vinyl polymer and a slip agent or polymer lubricant said modified polymer having a moiety comprising a cyclodextrin compound. The cyclodextrin compound, locked into the polymer struct... | 06/10/2008 |
| 7378469 | Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol) The invention provides a method for preparing a 1-benzotriazolylcarbonate ester of a water-soluble and non-peptidic polymer by reacting a terminal hydroxyl group of a water-soluble and non-peptidic polymer with di(1-benzotriazolyl)carbonate in the presence of an ami... | 05/27/2008 |
| 7368502 | Hydroxyphenyl cross-linked macromolecular network and applications thereof A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, such as artificial or synthetic cartilage. The network is made by first providing a polyamine or polycarboxylate macromolecule ... | 05/06/2008 |
| 7365123 | Grafted cyclodextrin Thermoplastic polymer compositions, films, continues, closures, laminates can comprise a modified vinyl polymer said modified polymer having a moiety comprising a cyclodextrin compound. The cyclodextrin compound, locked into the polymer structure, can absorb impurit... | 04/29/2008 |
| 7361726 | Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles Polymers containing poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles are disclosed along with methods of fabricating medical articles comprising these polymers. The medical articles generally comprise an implantable substrate having a ... | 04/22/2008 |
| 7361725 | Process of producing low molecular weight poly(hydroxyalkanoate)s from high molecular weight poly(hydroxyalkanoate)s In this invention, a process of thermal degradation of biodegradable bacterial polyesters poly(hydroxyalkanoate)s (PHAs) to lower molecular weight PHAs in controllable manner has been developed. The process involves using at least one additional component to ‘dilu... | 04/22/2008 |
| 7357940 | Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents Implantable or insertable medical devices are described. The medical devices comprise (a) a therapeutic agent and (b) a polymeric release region that controls the release of the therapeutic agent upon administration to a patient. The polymer release region comprises... | 04/15/2008 |
| 7351787 | Process for the preparation of activated polyethylene glycols A process for preparing activated polyethylene glycols is disclosed. In some embodiments, the process includes reacting a molten polyethylene glycol with an activator. In other embodiments, the process includes reacting a polyethylene glycol with an activator in the... | 04/01/2008 |
| 7335500 | Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides... | 02/26/2008 |
| 7332566 | Biocompatible crosslinked polymers with visualization agents Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having electrophilic and nucleophilic functional groups capable of reacting and cros... | 02/19/2008 |
| 7323184 | Compositions and methods for the treatment of wounds and the reduction of scar formation The present invention relates to methods and compositions for inhibiting scar formation on wound region. In certain embodiments, the methods include administering an alkalinization agent in combination with hyaluronic acid to a wound site to reduce the formation of ... | 01/29/2008 |
| 7291673 | Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments. ... | 11/06/2007 |
| 7261735 | Local drug delivery devices and methods for maintaining the drug coatings thereon Local drug delivery medical devices are utilized to deliver therapeutic dosages of drugs, agents or compounds directly to the site where needed. The local drug delivery medical devices utilize various materials and coating methodologies to maintain the drugs, agents... | 08/28/2007 |
| 7250461 | Organic formulations of conductive polymers made with polymeric acid colloids for electronics applications, and methods for making such formulations Organic compositions of conductive polymers are provided. The compositions have at least one polymer selected from polypyrrole, polythiophene, or combinations and at least one colloid-forming polymeric acid dispersed in a liquid medium that is at least 60% by weight... | 07/31/2007 |
| 7247314 | Biocompatible material composition adaptable to diverse therapeutic indications A biocompatible material genus serves as the foundation for multiple material composition species, each adapted to a specific therapeutic indication. ... | 07/24/2007 |
| RE39713 | Polymerizable biodegradable polymers including carbonate or dioxanone linkages Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and methods of preparation and use thereof are described. The macromers a... | 07/03/2007 |
| 7238364 | Compliant tissue sealants An improved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment, the system is compliant, in that it is capable of conforming to the three... | 07/03/2007 |
| 7232861 | Enzyme-mimicking polymers The present invention provides synthetic polymers having novel catalytic functions which mimic enzymatic reactions. The invention also provides a method for measuring glycated proteins such as glycated hemoglobin (HbA1c) and glycated albumin and for measuring their ... | 06/19/2007 |
| 7226972 | Process for cross-linking hyaluronic acid to polymers The present invention provides a process for the production of hyaluronic acid (HA) derivatives cross-linked with another polymer, in particular multiple e.g. double cross-linked hyaluronic acid derivatives. The invention also provides novel cross-linked derivatives... | 06/05/2007 |
| 7226615 | Expandable foam-like biomaterials and methods Liquid, injectable, aqueous solutions are transformed in situ to an expandable foam-like, space filling, and adherent biomaterial. Preferably, the foam-like biomaterial is the reaction product of a two-part liquid system to achieve the in situ formation thereof. The... | 06/05/2007 |
| 7217769 | Medical device with plasma cross-linked hydrophilic coating A medical device with a hydrophilic and lubricious coating, wherein the coating includes a hydrophilic polymeric unit layer deposited on the medical device and cross-linked with a plasma deposited double bond monomer. The hydrophilic polymeric unit can include ethyl... | 05/15/2007 |
| 7217845 | Bifunctional polyethylene glycol derivatives The present invention provides novel heterobifunctional and monobifunctional polyethylene glycol derivatives for the pegylation of therapeutically active proteins. The heterobifunctional PEGs which bear two different functional groups as well as the monobifunctional... | 05/15/2007 |
| 7208086 | Saccharide and support for chromatography A novel conjugate of a support material and an oligomer or polymer of a saccharide that is linked to the support material via urea linkages, and in which the oligomers or polymers are cross-linked via urea linkages provides a valuable stationary phase for chromatogr... | 04/24/2007 |
| 7202325 | Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles Polymers containing poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles are disclosed along with methods of fabricating medical articles comprising these polymers. The medical articles generally comprise an implantable substrate having a ... | 04/10/2007 |
| 7195640 | Coated medical devices for the treatment of vulnerable plaque Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of bioc... | 03/27/2007 |
| 7196059 | Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith Pharmaceutical compositions that include insulin, an insulin drug-oligomer conjugate, a fatty acid component, and a bile salt component or a bile salt component without a fatty acid component are described. The insulin drug is covalently coupled to an oligomeric moi... | 03/27/2007 |
| 7192984 | Compositions of polyacids and polyethers and methods for their use as dermal fillers The present invention relates to improved methods for filling the skin for cosmetic or medical purposes. Compositions comprising carboxymethyl cellulose (CMC), polyethylene oxide (PEO) and calcium ions can be made and have physical properties that depend on the amou... | 03/20/2007 |
| 7169178 | Stent with drug coating Coatings for stents that include a polymer and a drug are provided. A method of forming the coatings is also provided. ... | 01/30/2007 |
| 7169889 | Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin The present invention relates generally to hydrolyzable drug-oligomer conjugates, pharmaceutical compositions comprising such conjugates, and to methods for making and using such conjugates and pharmaceutical compositions. For example, a conjugate of insulin, PEG, a... | 01/30/2007 |
