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| Number | Title | Issue Date |
| 7425543 | Microencapsulated materials and method of making same A method of forming microspheres of a bioactive material, such as a protein polymer or drug by nebulizing a solubilized form of a material to be encapsulated and an encapsulating material, such as albumin, in a stirred chilled solvent system comprising a vegetable o... | 09/16/2008 |
| 7229949 | Safe delivery system for agriculturally active material A safe delivery system of agriculturally active material is formed using an encapsulation process. A microencapsulated suspension of agriculturally active material includes an encapsulating agent formed from a graft copolymer of starch and at least one vinyl monomer... | 06/12/2007 |
| 7223724 | Use of vascular endothelial growth factor to treat photoreceptor cells The present invention is directed to VEGF-2 polynucleotides and polypeptides and methods of using such polynucleotides and polypeptides. In particular, provided are methods of treating retinal disorders with VEGF-2 polynucleotides and polypeptides. ... | 05/29/2007 |
| 7144585 | Cilostazol preparation Provided is a cilostazol preparation which comprises incorporating a fine powder of cilostazol into a dispersing and/or solubilizing agent thereby to enhance the dispersibility and/or solubility. Further, provided is a process for improving absorbability of a slight... | 12/05/2006 |
| 7119062 | Methods and compositions for improved articular surgery using collagen The invention provides methods for treating post-surgical articular or incisional pain and/or discomfort in a patient. The invention further provides improved surgical methods and controlled release formulations for treating an articular injury of a joint in a patie... | 10/10/2006 |
| 7067153 | Microcapsule powder A process for making hydrophobicized powders of micro- and/or nanocapsules involving the steps of: (a) providing an aqueous polymer solution containing at least one active ingredient and at least one hydrophilic polymer; (b) providing an oil component heated to a te... | 06/27/2006 |
| RE39104 | Process for the production of dry pharmaceutical forms and the thus obtained pharmaceutical compositions A process for the production of a solid dispersion of at least one therapeutic agent in a hydrophilic carrier having enhanced solubility in an aqueous media comprising dissolving at least one therapeutic agent in a volatile organic solvent containing a very hydrophi... | 05/23/2006 |
| 7045496 | Use of vascular endothelial growth factor to treat photoreceptor cells The present invention is directed to VEGF-2 polynucleotides and polypeptides and methods of using such polynucleotides and polypeptides. In particular, provided are methods of treating retinal disorders with VEGF-2 polynucleotides and polypeptides. ... | 05/16/2006 |
| 6992047 | Method of microencapsulating an agricultural active having a high melting point and uses for such materials A method of producing a controlled release form of an agricultural active material includes the provision of an organic liquid composition in which the active is present, but where the liquid composition is free from aromatic solvents and is maintained below the nor... | 01/31/2006 |
| 6921538 | Therapeutic treatments for neuropsychiatric disorders Methods for treating psychiatric disorders include intracranial administration of a therapeutically effective amount of a neurotoxin, such as a botulinum toxin type A, to a human patient. ... | 07/26/2005 |
| 6916640 | Multi-layer cell encapsulation for tissue engineering A multi-layered microcapsule has an inner extracellular matrix and an outer shell. The inner extracellular matrix includes a first inner layer of biopolymer and a second intermediate layer of polymer that provides partial immune-protection and holds the first layer ... | 07/12/2005 |
| 6905875 | Non-disruptive three-dimensional culture and harvest system for anchorage-dependent cells A non-disruptive three-dimensional culture system allows cell growth and proliferation in three dimensions, permitting cell splitting without subjecting cells to disruptive conditions that affect cell structure and functions. An extracellular matrix provides a good ... | 06/14/2005 |
| 6878309 | Controlled release cooling additive composition A controlled-release additive composition for use in aqueous systems. The composition comprises a core containing at least one additive component and a polymeric coating encapsulating said core. The controlled released cooling additive composition slowly releases th... | 04/12/2005 |
| 6841515 | Production and use of biosolid granules This invention relates to the production and use of encapsulated and/or concentrically-constructed fertilizer or bioremediation granules such as, for example, granules of 0.5 mm to 10 mm in diameter constructed so that there are at least two components to the granul... | 01/11/2005 |
| 6821532 | Methods and compositions for the treatment of benign prostatic hypertrophy This invention relates to a composition for use in treating benign prostatic hyperplasia including a saw palmetto extract provided in an oral controlled release formulation which allows release of active ingredients in the intestinal tract and which allows the maint... | 11/23/2004 |
| 6730635 | Microcapsule suspensions The invention relates to microcapsule suspensions containing (A) a particulate disperse phase of microcapsules comprising: (1) sleeves that are reaction products of mixtures of toluylene diisocyanate and 4,4′-methylenebis-(cyclohexyl isocyanate) with... | 05/04/2004 |
| 6699500 | Sustained-release preparation capable of releasing a physiologically active substance Disclosed is a sustained-release preparation comprising 1) a polymer of lactic acid having a weight-average molecular weight of about 25,000 to about 60,000 and 2) a physiologically active substance, and which releases the physiologically active substance... | 03/02/2004 |
| 6692773 | Treatment of hyperproliferative skin disorders and diseases The invention relates to the use of one or more noble metals selected from silver, gold, platinum, and palladium but most preferably silver, in a nanocrystalline form, for the treatment of a hyperproliferative skin disorder or disease such as psoriasis. A... | 02/17/2004 |
| 6649151 | Cosmetic formulation The present invention includes a cosmetic formulation. The cosmetic formulation comprises a plurality of spheres having a first desiccated volume and having a second hydrated volume. The hydrated volume is greater than the desiccated volume.... | 11/18/2003 |
| 6645525 | Ionically formulated biomolecule microcarriers Compositions for sustained delivery of a biomolecule including an anionic polymer and a cationic polymer which ironically interact with each other and, optionally, with the biomolecule. Methods for making the compositions, including the step of combining ... | 11/11/2003 |
| 6620415 | Parkinson's disease treatment Methods for treating a movement disorder by intracranial administration to a human patient of a therapeutically effective amount of a neurotoxin, such as a botulinum toxin type A.... | 09/16/2003 |
| 6576677 | Medicinal compositions with relieved bitterness The present invention provides a composition alleviated in a bitter taste or the like of a medicament. The present invention relates to a composition comprising a basic medicament having an unpleasant taste and polyvinylpyrrolidone and/or copolyvidone; or... | 06/10/2003 |
| 6569809 | Package-mix agricultural chemical compositions having improved stability A concentrate package-mix composition comprising a water-soluble pesticide or plant growth regulator, for example a salt of the herbicide glyphosate, and a solid water-insoluble pesticide or plant growth regulator, for example the herbicide flumioxazin, i... | 05/27/2003 |
| 6562835 | Method for the treatment of urinary incontinence Urinary incontinence is alleviated in a mammal by administering to the mammal a urinary incontinence alleviating amount of dextromethorphan, dextrorphan, their mixtures and/or pharmaceutically acceptable salts, alone or in combination with a pharmacologic... | 05/13/2003 |
| 6544538 | Insecticidal composition An insecticidal bait composition which is particularly useful against social insects, such as cockroaches and ants is disclosed. The bait composition comprises a solid or semi-solid bait matrix including a food material for an insect and one or more non-m... | 04/08/2003 |
| 6540991 | Stabilized active materials A stabilized insect mating disruption pheromone compositions comprising an insect pheromone and 2,2'-Methylenebis(6-t-butyl-p-cresol). Methods of use and microcapsules containing these compositions are also provided.... | 04/01/2003 |
| 6534094 | Manufacturing process of microcapsules for sustained release of water soluble peptides A process for the manufacturing of microcapsules for sustained release of water soluble peptides, with adjustable release periods of between 1 to 18 weeks. The microcapsule wall are made of a biodegradable polymer. The process is based on the formation of... | 03/18/2003 |
| 6517859 | Microcapsules for administration of neuroactive agents The present invention relates to polymeric microspheres as injectable, drug-delivery vehicles for use to deliver bioactive agents to sites within the central nervous system, and for the stimulation of nerve fiber growth by implanting such microspheres wit... | 02/11/2003 |
| 6491953 | Controlled release compositions and method A controlled release composition comprising an adsorbent polymer, an active agent, and a release retardant is disclosed. The composition has an improved ability to release the active agent over an extended time period.... | 12/10/2002 |
| 6486099 | Microcapsule and process for production thereof A microcapsule (or microencapsulated product) having a uniform and smooth coating film and also an excellent performance of gradually liberating the content material is produced at a good particle size distribution while suppressing the occurrence of isol... | 11/26/2002 |
| 6479040 | Cosmetic formulation The present invention includes a cosmetic formulation. The cosmetic formulation comprises a plurality of spheres having a first desiccated volume and having a second hydrated volume. The hydrated volume is greater than the desiccated volume.... | 11/12/2002 |
| 6461545 | Method of solubilizing and encapsulating itraconazole Methods for preparing microspheres containing imidazole derivatives are provided. Also provided is the use of imidazole derivatives containing microspheres for treating fungal infections. Oral dosage forms for oral administration are also provided.... | 10/08/2002 |
| 6406689 | Compositions and methods for treatment of tumors and metastatic diseases Compositions and methods are provided which can be utilized in active immunization as a prophylactic treatment or a therapeutic treatment for tumors. The compositions are employed as injectable tumor vaccines or as preparations for intratumoral administra... | 06/18/2002 |
| 6379683 | Nanocapsules based on dendritic polymers The present invention relates to nanocapsules consisting of a lipid core forming or containing a lipophilic active principle, and of a water-insoluble continuous envelope comprising at least one dendritic polymer of polyester type containing optionally modified ter... | 04/30/2002 |
| 6344209 | Apatite-coated solid composition An apatite-coated solid composition which contains a biodegradable polymer and an apatite-coated solid composition which contains a biodegradable polymer and a medicinal substance have properties of sustained release and of osteoconductive activity.... | 02/05/2002 |
| 6306403 | Method for treating parkinson's disease with a botulinum toxin Methods for treating a movement disorder by intracranial administration to a human patient of a therapeutically effective amount of a neurotoxin, such as a botulinum toxin type A.... | 10/23/2001 |
| 6294192 | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents The present invention relates to triglyceride-free pharmaceutical compositions for delivery of hydrophobic therapeutic agents. Compositions of the present invention include a hydrophobic therapeutic agent and a carrier, where the carrier is formed from a ... | 09/25/2001 |
| 6287587 | Process for producing sustained-release preparation by in-water drying The present invention is to provide sustained-release microcapsules which contains high amount of a drug, suppresses initial release and shows stable release, and the production method of which comprises adding a physiologically active substance to biodeg... | 09/11/2001 |
| 6228291 | Process for preparing controlled-released chitosan microcapsule The present invention relates to a process for preparing the controlled-release chitosan microcapsule, more specifically to a process for preparing the sustained-release chitosan microcapsule capable of releasing at an appropriate rate for a long time, wh... | 05/08/2001 |
| 6228894 | Softgel-compatible composition containing retinol A softgel-compatible composition containing retinol comprises retinol-impregnated microparticles. The composition may include an optionally thickened silicone oil, or may include an emulsion comprising a silicone oil. Ascorbic acid may be present as ascor... | 05/08/2001 |
