"Flight by machines heavier than air is unpractical and insignificant, if not utterly impossible."
Simon Newcomb, astronomer ; Said in 1902, less than two years before the first flight at Kitty Hawk
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| Number | Title | Issue Date |
| 7390508 | Use of xenon with hypothermia for treating neonatal asphyxia The present invention relates to the use of xenon in the preparation of a medicament for the treatment of neonatal asphyxia in a neonatal subject, wherein said medicament is for use in combination with hypothermia. ... | 06/24/2008 |
| 7279457 | Rapid acting drug delivery compositions Drug formulations for systemic drug delivery with improved stability and rapid onset of action are described herein. The formulations may be administered via buccal administration, sublingual administration, pulmonary delivery, nasal administration, subcutaneous adm... | 10/09/2007 |
| 7235264 | Cerebral protection with a gas comprising xenon Xenon or xenon-containing gases and, where appropriate, an NO source are employed as medicament for cerebral protection. Cerebral protection is defined as reducing or preventing impairments of cerebral function of various causes, but especially secondary to perfusio... | 06/26/2007 |
| 7045152 | Treating pulmonary disorders with gaseous agent causing repletion of GSNO Pulmonary disorders in which the GSNO pool or glutathione pool in the lung is depleted and where reactive oxygen species in lung are increased, are treated by delivering into the lung as a gas, agent causing repletion or increase of the GSNO pool or protection again... | 05/16/2006 |
| 7029656 | Methods and formulations for the efficient delivery of water-insoluble drugs by nebulizer Formulations, methods and devices for producing formulations and methods for nebulizer delivery of formulations of water-insoluble drugs are provided. Also provided are methods for minimizing wastage of drugs administered by nebulizer, and for the achievement of qua... | 04/18/2006 |
| 7022685 | Very high molecular weight β-glucans The invention pertains to compositions and therapeutic and prophylatic methods for treating/preventing infections in an animal or human by administering a soluble β-glucan composition comprising β-glucan molecules having an average molecular weight of at least 1,0... | 04/04/2006 |
| 7011854 | Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g., rheumatoid arthritis, and of diseases with a strong inflammatory component, such as atherosclerosis, stroke... | 03/14/2006 |
| 6680284 | Method for producing powdery particle-reduced formulations with the aid of compressed gases For the preparation of pulverulent particle-reduced formulations with the aid of compressed gases, the solid compound to be formulated, a poorly soluble and usually bioactive active compound, is homogeneously ground together with 10-99% by weight (based o... | 01/20/2004 |
| 6653354 | NMDA antagonist comprising xenon The present invention relates to the use of xenon as a neuroprotectant and/or as an inhibitor of synaptic plasticity. In a preferred aspect, the xenon acts as an NMDA antagonist. The present invention also provides a method of reducing the level of activa... | 11/25/2003 |
| 6558618 | Anti-infection formulation and delivery method A method of dispersing, in water vapor, an anti-infective therapeutic composition (10) into the air in a room (36), in order to treat or prevent transmission of upper respiratory infections, includes: adding to a reservoir of liquid water in a vaporizer (... | 05/06/2003 |
| 6482391 | Medicaments for asthma treatment A method and apparatus is disclosed for treating asthma and other respiratory conditions. A medicament comprising a surface active phospholipid (SAPL) is prepared in the form of a fine powder and administered to the lungs in a gas stream. A preferred SAPL... | 11/19/2002 |
| 6365209 | Confectionery compositions and methods of making A novel encapsulated product is provided and includes: at least one active ingredient; at least one compressible material; and at least one tableting material; wherein the encapsulated product is in the form of a caplet having a diameter of from about 1 m... | 04/02/2002 |
| 6362225 | Target therapies for treating common viral infections Therapies and compositions are described for use in the treatment of a variety of common viral infections such as those of the upper respiratory tract, eye, stomach and intestines, and such viral lesions as cold sores, canker sores and those caused by gen... | 03/26/2002 |
| 6333057 | Composition and method for topical treatment of androgenic alopecia This invention relates to the topical and oral treatment of hair loss, especially androgenic alopecia, by providing formulations that include anti-androgens, especially extracts of the saw palmetto plant, co-enzyme Q, and acetyl carnitine, and optionally ... | 12/25/2001 |
| 6303156 | Noninvasive method for increasing or decreasing the body temperature of a patient The present invention is directed to a method for changing the body temperature of a patient by having them hyperventilate a gas mixture containing sulfur hexafluoride and oxygen. The method may be applied to cool patients in any clinical situation where ... | 10/16/2001 |
| 6274633 | NMDA antagonist The present invention relates to the use of xenon as an NMDA antagonist. In particular, the invention relates to a method of treatment comprising modulating the activity of an NMDA receptor in a mammal, the method comprising modulating the activity of the... | 08/14/2001 |
| 6174873 | Oral administration of adenosine analogs Disclosed are compositions including an adenosine analog, wherein the composition comprises a dosage form suitable for oral (co)administration. Also disclosed are compositions including adenosine analogs, wherein the composition is in a dosage form includ... | 01/16/2001 |
| 6138683 | Smokeless tobacco products containing antioxidants A composition for inclusion within a quantity of smokeless tobacco. The composition of antioxidants is capable of reducing free radical damage to the oro-pharyngeal cavity of a user resulting from consumption of smokeless tobacco. The composition includes... | 10/31/2000 |
| 6060045 | Vitaminized air freshener and room deodorizer pad Wicks or pads for use in vitaminized air fresheners and room deodorizer devices are disclosed, which permit devices occupants to directly receive and enjoy the benefits of vitamins with little or no effort intra-nasally as they breath the released volatil... | 05/09/2000 |
| 6001332 | Medical gas mixture A medical gas mixture which comprises from 20 to 70% oxygen, from 1 to 10% carbon dioxide and the balance, except for incidental constituents not adversely affecting the basic properties of the gas mixture, being helium. The subject mixtures are useful in... | 12/14/1999 |
| 5891427 | Vitaminized air freshner and room deodorizer Vitaminized air fresheners and room deodorizers are disclosed which permit occupants to directly receive and enjoy the benefits of vitamins with little or no effort intra-nasally. A method for the continuous release of a vitamin containing composition for... | 04/06/1999 |
| 5733939 | Fluorocarbons as anti-inflammatory agents A method for reducing the inflammatory response in tissues of a patient, by contacting the tissue with an effective, inflammation-reducing amount of a liquid or gaseous fluorocarbon.... | 03/31/1998 |
| 5660835 | Method of treating adenosine depletion A method of treating adenosine depletion in a subject in need of such treatment is disclosed. The method comprises administering to the subject folinic acid or a pharmaceutically acceptable salt thereof in an amount effective to treat adenosine depletion.... | 08/26/1997 |
| 5654288 | Stable NADH and NADPH compositions for sublingual administration NADH and/or NADPH is applied topically to the skin. It was surprising and totally unexpected to discover that NADH and NADPH are absorbed by the skin and penetrate the cutis to be taken up by the skin cells, where they stimulate certain enzymes which are ... | 08/05/1997 |
| 5593672 | Method of preparing and maintaining the immune system for lymphokine, cytokine and biological response modifier administration A method is provided for increasing and maintaining the quantity and activity of immune leukocyte effector cells in preparation for lymphokine and cytokine administration before and during treatment for disease pathogens. The method simultaneously up-regu... | 01/14/1997 |
| 5525347 | Composition and methods for treating performance anxiety The invention provides a pharmaceutical composition for treating performance anxiety and social phobia comprising a therapeutic amount for the treatment of a patient of a ଲ-adrenergic receptor blocking compound and an anti-diaphoretic compound. The ... | 06/11/1996 |
| 5470885 | Fluorocarbons as anti-inflammatory agents A method for reducing the inflammatory response in tissue of a patient, by contacting the tissue with an effective, inflammation-reducing amount of a liquid or gaseous fluorocarbon.... | 11/28/1995 |
| 5332727 | Stable, ingestable and absorbable NADH and NADPH therapeutic compositions A stable, ingestable and intestine-absorbable therapeutic composition comprising NADH or NADPH, or physiologically acceptable salts thereof, in a pill form. The pill has an outer surface covered by an acid stable protective coating. This oral form of NADH... | 07/26/1994 |
| 5320841 | Oral pharmaceutical compositions containing anthocyanosides Oral pharmaceutical compositions containing high content anthocyanosides, preferably higher than 80% w/w, suspended in fractionated coconut oil have higher bioavailability than water solutions or suspensions in other lipophilic carriers.... | 06/14/1994 |
| 5290540 | Method for treating infectious respiratory diseases A method of treating pneumonia caused by a microorganism by administering directly into the lower respiratory tract of a host an amount of an anti-inflammatory agent effective to reduce inflammation is provided. The method may further include administerin... | 03/01/1994 |
| 5130412 | Electrochemical drug release and article An electrically conducting self-doped carbazole polymer of the formula: ##STR1## wherein A is a bifunctional molecule capable of bonding to a positively charged molecule at one end and is capable of bonding to a flexible spacer group Z at another end... | 07/14/1992 |
| 4994441 | Dental anti-plaque and anti-caries agent Adhesion of bacteria in the buccal cavity which are responsible for the formation of dental plaque and caries is inhibited by kappa-caseino-glycopeptide compounds and desialylated derivaties thereof contained in compositions having a form suitable for bei... | 02/19/1991 |
| 4992420 | Dental anti-plaque and anti-caries agent Kappa-caseino-glycopeptide compounds and desialylated derivatives thereof and compositions containing the same are employed for treating bacteria in the buccal cavity which are responsible for the formation of dental plaque and caries.... | 02/12/1991 |
| 4963367 | Drug delivery compositions and methods Drug delivery compositions yeild new and unexpected degrees of stabilization, solubilization and delivery of incorporated medicaments, drugs, or other physiologically-active compounds. The compositions enable administration of drugs and other medically us... | 10/16/1990 |
| 4895719 | Method and apparatus for administering dehydrated liposomes by inhalation A system and method for administering a drug, at a selected dose, via the respiratory tract. Spray-dried liposome particles containing the selected dose of the entrapped drug are released into the air in aerosolized form, either by entrainment in an air o... | 01/23/1990 |
| 4832994 | Anti-smoking oral composition Anti-smoking oral preparations are provided containing a silver compound as the anti-smoking agent and a sweetener in which the silver compound is present in amounts of from 0.1 mg. to 2.5 mg. and the ratio of sweetness intensity based on sucrose to silve... | 05/23/1989 |
| 4794000 | Coacervate-based oral delivery system for medically useful compositions The present invention provides for an oral drug delivery system based on a two phase liquid coacervate system prepared from water and one or more surfactants selected from anionic, cationic, amphoteric, and non-toxic surfactants, polysaccharides, syntheti... | 12/27/1988 |
| 4650667 | Gas-emitting bath additive composition Gas-emitting bath additive compositions are stably preserved over a long term. They comprise a carbonate, an organic acid, and a stabilizer which is selected from magnesium oxide, sodium aluminate and a mixture thereof. Magnesium oxide and sodium aluminat... | 03/17/1987 |
| 4626427 | Cardamom seed preparation being effective against bad breath Preparation being effective against bad breath, particularly caused by strongly smelling food stuffs or cigarettes, alcohol and the like, consisting of cardamom seeds which are individually or jointly coated by a shell mass comprising a sugar mass or the ... | 12/02/1986 |
| 4557754 | Bis-(N,N-dimethyl-N-carbodecyloxymethyl-N-ethylene-ammonium)-sulphide dichloride and use thereof A novel compound bis-(N,N-dimethyl-N-carbodecyloxymethyl-N-ethyleneammonium)-sulphide dichloride of the formula ##STR1## A method for preparing said novel compound comprising quaternization of bis-(ଲ-dimethylaminoethyl)-sulphide with monoc... | 12/10/1985 |