3M employee and church chorister Art Fry needed something to temporarily mark pages in his hymnal. He was in luck because his colleague, Spencer Silver, accidentally developed a glue that was too weak for other purposes. After initially discouraging consumer response, Post-it Notes became a hit in 1979.
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| Number | Title | Issue Date |
| 6946426 | Process to prepare aqueous formulations Provided is a method of formulating hydrophobic pesticides comprising emulsifying an aqueous phase and a water-immiscible phase to form a formulation; wherein the aqueous phase is comprised of water and optionally a freeze/thaw agent, one or more emulsifiers, or com... | 09/20/2005 |
| 6946120 | Pharmaceutical composition A pharmaceutical composition for topical administration, including, as the pharmaceutically active component, at least 5% by weight, based on the total weight of the composition of a piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; an a... | 09/20/2005 |
| 6896897 | Flexible applicator for applying oil-in-water emulsion with improved stability A flexible applicator for applying an oil-in-water emulsion comprises: (1) an allantoin-containing oil-in-water emulsion; and (2) a flexible element that adsorbs or absorbs the emulsion such that the emulsion is applied to the skin of a patient on whom the flexible ... | 05/24/2005 |
| 6864274 | Allantoin-containing skin cream An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The pH of the composition is in a range of from about 3.0 to about 6.0; preferably, the p... | 03/08/2005 |
| 6673826 | Methods for treatment of inflammatory diseases An improved method of treating skin diseases comprises applying to the skin of a patient suffering such a skin disease an allantoin-containing composition in a therapeutically effective quantity. The allantoin-containing composition is a water-in-oil emul... | 01/06/2004 |
| 6531500 | Methods for treatment of inflammatory diseases An improved method of treating skin diseases comprises applying to the skin of a patient suffering such a skin disease an allantoin-containing composition in a therapeutically effective quantity. The allantoin-containing composition is a water-in-oil emul... | 03/11/2003 |
| 6465442 | Topical application of muscarinic and opioid agents for treatment of tinnitus The present invention relates to a compositions and methods for treating tinnitus. In preferred embodiments of the invention, muscurinic and/or opioid agents are administered to the affected ear in amount effective to relieve one or more tinnitus symptoms... | 10/15/2002 |
| 6458383 | Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin A delayed release pharmaceutical dosage form for oral administration of a hydrophilic drug, e.g., a polysaccharide drug such as low molecular weight heparin, are provided. The dosage form comprises a composition of: (a) a therapeutically effective amount ... | 10/01/2002 |
| 6451339 | Compositions and methods for improved delivery of hydrophobic agents The present invention relates to triglyceride-free pharmaceutical compositions for delivery of hydrophobic therapeutic agents. Compositions of the present invention include a hydrophobic therapeutic agent and a carrier, where the carrier is formed from a ... | 09/17/2002 |
| 6329413 | Allantoin-containing skin cream An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The pH of the composition is in a range of from about 5.0 to about 6.5. The co... | 12/11/2001 |
| 6309663 | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents The present invention relates to pharmaceutical compositions, pharmaceutical systems, and methods for enhanced absorption of hydrophilic therapeutic agents. Compositions and systems of the present invention include an absorption enhancing carrier, where t... | 10/30/2001 |
| 6113921 | Topical and transdermal delivery system utilizing submicron oil spheres The present invention relates to a delivery system which includes a bioactive drug or cosmetic substance presented in the form of submicron oil spheres alone, or drugs or cosmetic substances in a combination with the oil spheres in an aqueous suspension o... | 09/05/2000 |
| 6106848 | Topically applicable O/W emulsions having high glycol content and at least one biologically active agent Stable, topically applicable oil-in-water bioaffecting emulsions having intermediate viscosity, characteristically ranging from 3 to 10 Pa.multidot.s, comprise (a) from 30% to 50% by weight of at least one pro-penetrating glycol, (b) at least one emulsify... | 08/22/2000 |
| 6066328 | Cosmetic or dermatological composition comprising an oil-in-water emulsion comprising oily globules with a lamellar liquid crystal coating The present invention relates to a cosmetic or dermatological composition comprising an emulsion of oil-in-water type formed of oily globules which are each provided with a lamellar liquid crystal coating and are dispersed in an aqueous phase. Each oily g... | 05/23/2000 |
| 6011022 | Topical application of muscarinic analgesic drugs such as neostigmine The invention is directed to methods and pharmaceutical compositions for the topical administration of analgesic drugs which affects peripheral muscarinic receptors such as neostigmine. In particular, the invention relates to topical administration of an ... | 01/04/2000 |
| 6001346 | Aqueous emulsion comprising biodegradable carrier for insect pheromones and methods for controlled release thereof A sprayable or solid biodegradable wax carrier for insect pheromones and a method for constant release rate of the pheromone from the biodegradable wax. A composition comprising a pheromone and paraffin wax formulated as an aqueous emulsion or a solid sui... | 12/14/1999 |
| 5964691 | Composition useful for gelled cosmetic stick A dispersion of dibenzylidene sorbitol acetal (DBS) in an organic liquid selected from alkylene glycols and polyalkylene glycols is provided wherein the DBS has a moisture content of greater than 2 wt. %, to inhibit the dispersion from gelling prematurely... | 10/12/1999 |
| 5928632 | Surfactant free rinse-off skin conditioning formulation A surfactant free skin conditioning composition comprising a primary emollient of a gelled mineral oil, and emulsion stabilizer including at least one of a high molecular weight homopolymer of polyacrylic acid or a copolymer having a major proportion of a... | 07/27/1999 |
| 5925681 | Blooming, disinfectant concentrate compositions Concentrated aqueous liquid disinfectant compositions which exhibit a blooming effect when diluted in a larger volume of water are provided. The concentrate compositions include non-phenolic constituents to provide a disinfecting effect, and are non pine-... | 07/20/1999 |
| 5925364 | Cosmetic or dermatological composition comprising an oil-in-water emulsion comprising oily globules with a lamellar liquid crystal coating The present invention relates to a cosmetic or dermatological composition comprising an emulsion of oil-in-water type formed of oily globules which are each provided with a lamellar liquid crystal coating and are dispersed in an aqueous phase. Each oily g... | 07/20/1999 |
| 5679351 | Clove oil as a plant fungicide A clove oil formulation which inhibits soil-borne fungal diseases is disclosed. The formulation includes about 70-90% by weight rectified clove oil, and about 2-30% by weight surfactant. The surfactant includes about 15-95% by weight nonionic compounds su... | 10/21/1997 |
| 5607698 | Method of preserving ophthalmic solution and compositions therefor A preservative for ophthalmic solutions having an active ingredient is provided, having a hydrogen peroxide content of about 0.001% to about 0.10% by weight; and diethylene triamine penta(methylene phosphonic acid) or a physiologically compatible salt the... | 03/04/1997 |
| 5478561 | Process for the preparation of stable complex multiple emulsions of the water-oil water systems The invention relates to a novel process for the preparation of stable complex multiple emulsions of the water-oil-water type which are well suited for use in cosmetic preparations. The primary emulsions of the W/O type are prepared in the presence of bot... | 12/26/1995 |
| 4781914 | Sunscreen and moisturizer Skin treatment compositions such as sun screen compositions and moisturizer compositions are provided which include polyglyceryl-8 oleate to impart moisture resistance or substantivity to the compositions.... | 11/01/1988 |
| 4695450 | Anhydrous emulsions and the use thereof Anhydrous emulsion with an oil phase (o) and a hydrophilic phase (p) of water-soluble, but anhydrous liquids, particularly as a filler matrix for medicinal preparations in capsules, which on the one hand does not attack the capsule wall and on the other p... | 09/22/1987 |
| 4515810 | Composition of matter A pharmaceutical composition of matter useful as a topical medicament which comprises an E-type prostaglandin compound or other water unstable active ingredient in a quick-breaking foam formulation to be dispensed from a pressurized container through a me... | 05/07/1985 |