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| Number | Title | Issue Date |
| 7402561 | Compositions and methods for inhibiting abnormal cell growth In the US about ⅓ of college women show evidence of HPV infection. The clinical problem may be even larger in developing countries. There are currently no effective therapies for HPV infections, aside from therapeutic cone biopsies, which often are followed by rec... | 07/22/2008 |
| 7357930 | Methods and formulations for targeting infectious agents bearing host cell proteins A formulation is disclosed for the treatment of diseases caused by an infectious agent which acquires host membranes protein during its life cycle. The formulation is a targeting pharmaceutical composition. It comprises a ligand capable of binding the host membrane ... | 04/15/2008 |
| RE40246 | Method for the suppression of viral growth A method for suppressing undesired viral growth in a host which comprises administering to the host an effective amount of a compound of the formula: wherein R1, R2, R3 and R4 are indep... | 04/15/2008 |
| 7202231 | β-Cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases Methods of reducing the risk of transmission of a sexually transmitted pathogen by contacting the pathogen or cells susceptible to infection by the pathogen with a β-cyclodextrin are provided. Methods for reducing the risk of transmission of a sexually transmitted ... | 04/10/2007 |
| 7151091 | Compositions and methods for preventing infection This invention relates to cholesterol-sequestering agents and methods of using cholesterol-sequestering agents to prevent infection. The compositions of the invention can be used to reduce or prevent maternal to fetal transmission of a microorganism and/or to reduce... | 12/19/2006 |
| 7135195 | Treatment of humans with colloidal silver composition We disclose a colorless composition comprising silver particles and water, wherein said particles comprise an interior of elemental silver and an exterior of ionic silver oxide, wherein the silver particles are present in the water at a level of about 5–40 ppm, an... | 11/14/2006 |
| 7087249 | Treatment of mucosal membranes The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and preferably in a nanocrystalline form, for reducing inflammation or infect... | 08/08/2006 |
| 7078392 | Cellulose sulfate and other sulfated polysaccharides to prevent and treat papilloma virus infection and other infections A method for treating and preventing various infections, including papilloma virus and fungal and parasitic infections is provided. In particular, an effective amount of a sulfated polysaccharide, such as cellulose sulfate and dextran sulfate are administered to pre... | 07/18/2006 |
| 7048924 | Combination antiviral and interleukin-2 therapy for HIV infection Methods for promoting immunologic control of human immunodeficiency virus (HIV) in an HIV-infected subject are provided. The methods comprise administering to the subject highly active antiretroviral therapy (HAART) for at least one cycle of an intermittent dosing r... | 05/23/2006 |
| 7018661 | Aluminum-zirconium compound-based treatment for herpes simplex virus lesions Aluminum-zirconium compounds applied topically, usually in a cream, gel, or other base, to lesions caused by any strain or type of Herpes simplex virus in humans and in other animals, will lessen the symptoms of the lesions, speed their healing, and possibly make th... | 03/28/2006 |
| 6911478 | Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitric oxide-releasing amidine- a... | 06/28/2005 |
| 6864244 | Anhydrous crystalline 1-[4(S)-azido-2(S),3(R)-dihydroxy-4-(hydroxymethyl)-1(R)-cyclopentyl]cytosine hemisulfate as useful as an antiviral agent The present invention relates to the hemisulfate salt of 1-[4(S)-azido-2(S),3(R)-dihydroxy-4-(hydroxymethyl)-1(R)-cyclopentyl]cytosine (Ia) with improved stability and physical properties which facilitate manufacturing, handling and formulating I and polymorphic cry... | 03/08/2005 |
| 6846810 | Antiviral nucleoside derivatives The present invention relates to nucleoside derivatives for the treatment of Hepatitis C viral infections including compounds of formula I, pharmaceutical compositions comprising these compounds and methods for treatment or prophylaxis of Hepatitis C Virus mediated ... | 01/25/2005 |
| 6835717 | β-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases Methods of reducing the risk of transmission of a sexually transmitted pathogen by contacting the pathogen or cells susceptible to infection by the pathogen with a β-cyclodextrin are provided. Methods for reducing the risk of transmission of a sexually transmitted ... | 12/28/2004 |
| 6770635 | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions Adverse inflammatory reactions can be treated by administrating to an organism a composition having diglucosylamine as the active ingredient. The preferred compound is di-Beta-D-glucopyranosylamine. A simple method for making diglucosylamine in high purity is obtain... | 08/03/2004 |
| 6750254 | Nitric oxide-releasing amidine—and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitric oxide-releasing amidine- a... | 06/15/2004 |
| 6730329 | Zinc containing compositions for anti-viral use One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one analgesic) at least one hydrocarbyl containing compound, and water. Anoth... | 05/04/2004 |
| 6709681 | Acidified nitrite as an antimicrobial agent The present invention provides a dosage form for the treatment of bacterial, viral or fungal conditions which comprises, a pharmaceutically acceptable acidifying agent in an amount sufficient to reduce the pH at an environment of use to below pH4, and a pharmaceutic... | 03/23/2004 |
| 6703049 | Angiogenesis inhibitor The present invention relates to a novel angiogenesis inhibitor, more particularly, arsenolite (solid As4 O6) and composition containing the same. The arsenolite of the present invention inhibits endothelial cell proliferation and tu... | 03/09/2004 |
| 6656936 | Carnitine analogues as topical, microbicidal spermicides Acylcarnitine analogues having alkyl side chains of 10 to 30 carbon atoms display excellent spermicidal and anti-HIV activity, a well as being potent inhibitors of the growth of Candida albicans.... | 12/02/2003 |
| 6652874 | Pharmaceutical preparations and methods for their regional administration Formulations have been developed for regional delivery of drugs, for example, into a cavity such as the pelvic region, peritoneal region, or directly on organs of interest. Regional delivery increases comfort and bioavailability of the drug, resulting in ... | 11/25/2003 |
| 6630477 | Therapeutic nucleoside compound The present invention relates to (1R,4S)-4-(6-amino-9H-purin-9-yl)-2-cyclopentene-1-methanol and its use in medical therapy for the treatment of hepatitis B infection.... | 10/07/2003 |
| 6627229 | Antiviral agent and method of producing the same An antiviral agent of an antiviral ability against various viruses and a method of producing the same are provided. A heat treatment is applied to a calcium-containing substance represented by calcium carbonate-containing substances originating from the a... | 09/30/2003 |
| 6579521 | Methods of therapy for HIV infection Methods for promoting immunologic control of human immunodeficiency virus (HIV) in an HIV-infected subject are provided. The methods comprise administering to the subject highly active antiretroviral therapy (HAART) for at least one cycle of an intermitte... | 06/17/2003 |
| 6541461 | Compounds having antiviral activity In order to provide the anti-retrovirus active compound with low anti-coagulant action and low cytotoxicity, compounds comprising glycoside or the salt thereof wherein lipid is linked to position 2 of sialic acid having all hydroxyl groups at positions 4,... | 04/01/2003 |
| 6514980 | Nucleoside analogs in combination therapy of herpes simplex infections A pharmaceutical product comprising a nucleoside analogue active against herpes simplex virus, such as acyclovir/valaciclovir or penciclorivir/famciclovir, and an immunosuppressant, as a combined preparation for simultaneous, separate or sequential use in... | 02/04/2003 |
| 6486166 | Suppression of cyclin kinase 2 activity for prevention and treatment of DNA viral infections An important aspect of the present invention is a method for inhibiting proliferation of a DNA virus dependent upon events associated with cell proliferation for replication. The DNA virus includes any of the herpesvirus family, and most particularly huma... | 11/26/2002 |
| 6475526 | Zinc containing compositions for anti-viral use One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one analgesic) at least one hydrocarbyl containing compound, and w... | 11/05/2002 |
| 6458346 | Broad spectrum microbicidal and spermicidal compositions, devices, and methods Microbicidal and spermicidal devices, methods, and compositions containing sodium dodecyl sulfate or related anionic surfactants as active ingredients for the prevention and control of pregnancy and sexually transmitted disease, including conditions cause... | 10/01/2002 |
| 6455565 | Method for inhibiting skin lesion formation using histamine as the active ingredient A pharmaceutical composition of water, water soluble vinyl polymer gel, amine alcohol dispersant and IEP is used topically to treat herpes labialis and aphthous stomatitis lesions, and also to treat herpes genitalis, chicken pox, allergic conjunctivitis, ... | 09/24/2002 |
| 6429208 | Methods and compositions for restoring impaired cellular immune function The effect of HIV components on lymphocytes, as exemplified by peripheral blood mononuclear cells (PBMC) in retarding their proliferation can be reversed by inhibiting the PKA/cAMP pathway. By using protocols which inhibit this pathway, the ability of lym... | 08/06/2002 |
| 6413938 | Benzimidazole derivatives for the treatment of viral infections According to a first aspect of the invention there is provided compounds of formula (I): ##STR1## wherein: R1 is hydroxy; O-acetyl; or a halo atom; R2 is hydroxy; O-acetyl; or a halo atom; R3 is hydrogen; a halo atom; azido; C | 07/02/2002 |
| 6410570 | Methods of inactivating a virus and controlling viral replication An antiproliferative, antiinflammatory, antiinfective, immunization agent of a metal ion chelating agent such as picolinic acid or derivatives thereof, and methods of using the same. The agents chelate metals in metal containing protein complexes required... | 06/25/2002 |
| 6368637 | Method and composition for topical treatment of viral lesions A process for treating active viral lesions, such as herpes lesions and warts, on persons or animals, in which an active lesion containing a virus is scrubbed or debrided, an aqueous reagent solution containing neutral red and free chlorine is applied to ... | 04/09/2002 |
| 6365166 | Gel formulations for topical drug delivery Pharmaceutical gel formulations for topical drug delivery include drug, colloidal silicon dioxide, triacetin and, preferably, propylene glycol. The gel formulations are well suited for topical delivery of the drug 4-amino-2-ethoxymethyl-,-di... | 04/02/2002 |
| 6350467 | Pharmaceutical preparations of glutathione and methods of administration thereof A method of increasing glutathione levels in mammalian cells comprising administering an oral bolus of encapsulated pharmaceutically stabilized glutathione in a rapidly dissolving formulation to a mammal on an empty stomach. Pharmaceutical formulations in... | 02/26/2002 |
| 6284249 | Fusion polypeptide having the C protein and E1 protein of hepatitis C virus The invention concerns a pharmaceutical composition for treating or preventing C hepatitis (HCV), induced infections, which in a preferred embodiment, comprises a main active principle, (i) a fusion polypeptide, including the HCV capsid polypeptide (C191)... | 09/04/2001 |
| 6274146 | Biologically active phytogenous proteoglycan and a method of making thereof A biologically active phytogenous proteoglycan not having hemagglutinating activity via water solution obtained by disintegration of divisible plant cells from young potato plants, Solanum tuberosum of the Family Solanaceae, fractionated and concentrated ... | 08/14/2001 |
| 6274132 | Method for treating HIV with chlorine dioxide and a phosphate compound A method and solution or gel composition containing activated chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for lubricating the vagina a... | 08/14/2001 |
| 6258385 | Tetrasilver tetroxide treatment for skin conditions The invention relates to the use of electron active molecular crystals comprising tetrasilver tetroxide (Ag4 O4) for the treatment and cure of dermatological skin conditions (diseases) ranging from dermatitis, acne and psoiasis to he... | 07/10/2001 |
