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Class 514/924 - TUBERCULOSIS


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter involving the treatment or prevention of
No. of patents: 46
Last issue date: 10/28/2008


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NumberTitleIssue Date
7442393Herbal extracts of Salicornia species, process of preparation thereof, use thereof against tuberculosis
The present invention relates to extracts of Salicornia species. The present invention particularly relates to extracts of Salicornia species which show antitubercular activity. The present invention also relates to a process for the preparation of nov...
10/28/2008
7214364Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, ...
05/08/2007
7150888Methods and apparatus to prevent colds, influenzaes, tuberculosis and opportunistic infections of the human respiratory system
Strong vapors from eucalyptus oil and tea tree oil are inhaled periodically to prevent respiratory system diseases including colds, flus, pneumonia, tuberculosis, and opportunistic infections in individuals having cystic fibrosis. Apparatus for the periodic inhalati...
12/19/2006
7135195Treatment of humans with colloidal silver composition
We disclose a colorless composition comprising silver particles and water, wherein said particles comprise an interior of elemental silver and an exterior of ionic silver oxide, wherein the silver particles are present in the water at a level of about 5–40 ppm, an...
11/14/2006
7122577Composition comprising a carrier and a purified mycobacterial lipid cell-wall component and its use in the treatment and diagnosis of disease
A composition including a purified lipid cell-wall component or analog or derivative thereof and a suitable pharmaceutical carrier, medium, excipient or adjuvant is described. The composition is useful in prophylactic and therapeutic methods of treating a microbial ...
10/17/2006
6989157Dry powders of metal-containing compounds
Dry powders of metal-containing compounds are disclosed. Methods of preparing and using the dry powders, particularly in the treatment of a subject having a condition, are also disclosed. The metal-containing material can be, for example, an antimicrobial material, ...
01/24/2006
6951961Methods of use and compositions for the diagnosis and treatment of infectious disease
Methods and compositions for treating disease caused by microorganisms, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the treatment of infectious diseases are provided. In one embodiment, these method...
10/04/2005
6866871Dry powders of metal-containing compounds
Dry powders of metal-containing compounds are disclosed. Methods of preparing and using the dry powders, particularly in the treatment of a subject having a condition, are also disclosed. The metal-containing material can be, for example, an antimicrobial material, ...
03/15/2005
6852484Methods for the identification of inhibitors of asparagine synthase as antibiotics
The present inventors have discovered that Asparagine Synthase is essential for fungal pathogenicity. Specifically, the inhibition of Asparagine Synthase gene expression in fungi results in no signs of successful infection or lesions. Thus, Asparagine Synthase can b...
02/08/2005
6835755Naphthoquinone derivatives and their use in the treatment and control of tuberculosis
Naphthoquinone derivatives of Formula (1): wherein R, represents an OH group, methyl ether, ethyl ether or a similar ether, R1 represents a methyl, ethyl or similar aliphatic hydrocarbon derivative: R2 and R3 each independently represent hydrogen or a group selected...
12/28/2004
6733963Methods for the identification of inhibitors of 3-isopropylmalate dehydratase as antibiotics
The present inventors have discovered that 3-Isopropylmalate dehydratase is essential for fungal pathogenicity. Specifically, the inhibition of 3-Isopropylmalate dehydratase gene expression in fungi results in no signs of successful infection or lesions. Thus, 3-Iso...
05/11/2004
6566354Method for treatment of bacterial infections with once or twice-weekly administered rifalazil
A method for treatment of bacterial infections with rifalazil administered once-weekly or twice-weekly. A method for treatment of tuberculosis caused by Mycobacterium tuberculosis, infections caused by Mycobacterium avium complex, infections caused by Chl...
05/20/2003
6517845Mycobacterium tuberculosis superoxide dismutase
The invention relates to Mycobacterium tuberculosis superoxide dismutase antibodies, methods of using them for detection of M. tuberculosis, methods of testing for an inhibitor of an M. tuberculosis superoxide dismutase, and methods of detecting tuberculo...
02/11/2003
6514541Formulation comprising thymol useful in the treatment of drug resistant bacterial infections
A formulation useful in the treatment of drug resistant bacterial infections comprising an effective amount of thymol obtained from the plant Trachyspermum ammi, mint oil containing an appropriate amount of monoterpenes obtained from a hybrid of Mentha sp...
02/04/2003
6433013Composition comprising a carrier and a purified mycobacterial lipid cell-wall component and its use in the prevention, treatment and diagnosis of disease
A composition comprising a purified lipid cell-wall component or analog or derivative thereof and a suitable pharmaceutical carrier, medium, excipient or adjuvant is described. The composition is useful in prophylactic and therapeutic methods of treating ...
08/13/2002
6403623Heterocyclic antituberculosis agents
Method for treating tuberculosis with 2-(2-substituted-phenyl)-2-oxazolines and related 5-membered heterocycles represented by the formula ##STR1## Y1 is e.g. an ester or amide forming group, and X is O, S, or NH; and pharmaceutically acceptabl...
06/11/2002
6316433Method for treatment of bacterial infections with once or twice-weekly administered rifalazil
A method for treatment of bacterial infections with rifalazil administered once-weekly or twice-weekly. A method for treatment of tuberculosis caused by Mycobacterium tuberculosis, infections caused by Mycobacterium avium complex, infections caused by Chl...
11/13/2001
6284255Compounds and methods for treatment and diagnosis of mycobacterial infections
The present invention provides polypeptides comprising an immunogenic portion of a M. vaccae soluble protein and DNA molecules encoding such polypeptides, together with methods for their use in the diagnosis and treatment of mycobacterial infection. Metho...
09/04/2001
6238661Use of bacterial phage associated lysing enzymes for treating various illnesses
Compositions and methods for the prophylactic and therapeutic treatment of bacterial infections are disclosed which comprise administering to an individual an effective amount of a composition comprising an effective amount of lytic enzyme and a carrier f...
05/29/2001
6214789Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products
The present invention relates to methods for treating a subject suffering from infection with Mycobacteria, such as M. leprae or M. tuberculosis comprising administering to the subject a composition comprising a bactericidal/permeability-inducing (BPI) pr...
04/10/2001
6203822Gallium-containing compounds for the treatment of infections caused by intracellular pathogens and pathogens causing chronic pulmonary infection
This invention relates to the use of gallium-containing compounds, to inhibit intracellular pathogens including pathogens that are members of the genus Mycobacteria, Legionella, Histoplasma, and Leishmania and to organisms causing chronic pulmonary infect...
03/20/2001
6083922Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis
A method for treatment, prevention and containment of acute and chronic tuberculosis using a preservative-free concentrated tobramycin aerosol formulation delivering tobramycin to the lung endobronchial space including alveoli in an aerosol having mass me...
07/04/2000
5998420Method for treating Mycobacterium tuberculosis
The present invention is directed to a method for treating tuberculosis in a mammal which comprises administering to the mammal a therapeutically effective amount of an inhibitor compound that inhibits an enzyme in the branched chain amino acid biosynthet...
12/07/1999
5837732Antimycobacterial compounds and method of using same
The present invention provides a compound having the structure: ##STR1## wherein R is a branched or unbranched C1-C30 alkyl, alkenyl or alkynl; or a branched or unbranched C1-C30 alkyl, alkenyl or alkynl substituted with S, O, N, P, SO2, F...
11/17/1998
5798391Injectable solution of benzalkonium fluoride
Solution administrable by intravascular injection in a human or an animal which comprises an effective amount up to 0.23% by weight of a benzalkonium fluoride having the formula: ##STR1## where R is an alkyl radical which may vary between C8
08/25/1998
5648392Antimycobacterial compounds and method of using same
The present invention provides a compound having the structure: ##STR1## wherein R is a branched or unbranched C1-C30 alkyl or alkenyl; or a branched or unbranched C1-C30 alkyl or alkenyl substituted with S, O, N, P, SO2, F, C1, Br, or I, ...
07/15/1997
5624912Method of treating HIV infection and related secondary infections with defibrotide
Oligonucleotides, polynucleotides and derivatives thereof, such as defibrotide, are agents of genetic modulation at the levels of transcription, translation, secondary messengers and cellular signal transduction systems. Such agents can be used to treat H...
04/29/1997
5565473Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists
Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in t...
10/15/1996
5529778Ayurvedic composition for the prophylaxis and treatment of AIDS, flu, TB and other immuno-deficiencies and the process for preparing the same
An ayurvedic composition for prophylaxis and treatment of AIDS, flu, TB, and other immuno-deficiency conditions, and for liver diseases such as hepatitis and sclerosis, includes prescribed doses of extracts or isolates of two multi-component drugs in sele...
06/25/1996
5439891Process for preparation of pharmaceutical composition with enhanced activity for treatment of tuberculosis and leprosy
A new pharmaceutical composition for the treatment of tuberculosis and leprosy, said composition comprising piperine in combination with known antituberculosis or antileprosy drugs or the mixtures thereof....
08/08/1995
5162361Method of treating diseases associated with elevated levels of interleukin 1
The present invention relates to a method of treating diseases associated with elevated levels of interleukin 1 (IL-1) including inflammatory diseases such as arthritis, skin hypersensitivity and endotoxemia. More specifically, the invention relates to a ...
11/10/1992
5089475Treatment of ventilator dependency with growth hormone
The invention relates to a method of treating pulmonary dysfunction in a mammal comprising administration of growth hormone to said mammal. In one embodiment wherein the pulmonary dysfunction results in ventilator dependency, the use of the method of this...
02/18/1992
4962111Pyrazinoic acid esters as antituberculosis agents
Pyrazinoic esters have been prepared. Compounds of this group are effective against mycobacteria including Mycobacteria tuberculosis, pyrazinamide-resistant Mycobacteria tuberculosis, Mycobacteria bovis and Mycobacteria kansasii....
10/09/1990
4851437Tung oil compositions and use for treatment of body deficiencies
Various tung oil or tung oil fatty acid compositions and use thereof for treating at least some symptoms of body defense deficiencies in patients having said symptoms....
07/25/1989
4353826Substituted rifamycins
Antibiotically active compounds derived from rifamycin S or from the corresponding hydroquinone, rifamycin SV, or from derivatives at least partially hydrogenated in positions 16, 17; 18, 19; 28, 29, such as the 16, 17; 18, 19--tetrahydro- or the 16, 17; ...
10/12/1982
4352800Adjuvant for promoting absorption of therapeutically active substances through the digestive tract
The enamine derivatives having following formula ##STR1## promote absorption of therapeutically active substances through the digestive tract into the blood stream and are able to effectively elevate the concentration of such active substances in the...
10/05/1982
43270963-Amidino ansamycins
Novel 3-amidino rifamycins having the formula: ##STR1## wherein Y is --H or --COCH3 ; R1 and R2 may be linear or branched alkyl having from 1 to 7 carbon atoms and alkenyl having 3 or 4 atoms and R2 may be ...
04/27/1982
43072296,6'-Diesters of trehalose and process for the synthesis thereof
An improved process is described for synthesizing simple and complex 6,6'-diacyl esters of trehalose and intermediates useful therein. Novel 6,6'-diacyl esters of trehalose and novel intermediates useful in the process of the invention are also disclosed....
12/22/1981
42936963-Substituted phenylthiazolo[3'2':1,2]imidazo[4,5-b]pyridine-2-alkanoic acids
3-Substituted phenythiazolo[3'2':1,2]imidazo[4,5-b]pyridine-2-alkanoic acids and their use as immunomodulating agents are disclosed....
10/06/1981
4123533Fused pyrimidine derivatives and compositions for treating atherosclerosis containing them
Compounds of the formula: ##STR1## or pharmaceutically acceptable salts thereof are disclosed wherein R is hydrogen or C1 to C6 alkyl; R2 and R3 are each hydrogen or together form a valency bond; R6 i...
10/31/1978
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