Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 7851512 | Composition containing artemisinin for treatment of malaria The present invention provides a novel combination comprising artemisinin in the form of tablets and related dosage forms for pediatric use, such as granules, suppository, suspension syrup and dry powder, for the treatment of human malarias including multiple-resist... | 12/14/2010 |
| 7157449 | Medicament for the treatment of diseases caused by parasitic protozoa The present invention relates to the use of an inhibitor of CTP synthetase, such as a glutamine analogue, and a substance capable of suppressing toxic effects thereof in vivo, in the manufacture of a medicament for the treatment of a disease caused by a parasitic pr... | 01/02/2007 |
| 7135195 | Treatment of humans with colloidal silver composition We disclose a colorless composition comprising silver particles and water, wherein said particles comprise an interior of elemental silver and an exterior of ionic silver oxide, wherein the silver particles are present in the water at a level of about 5–40 ppm, an... | 11/14/2006 |
| 7084132 | Artemisinins with improved stability and bioavailability for therapeutic drug development and application A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic ... | 08/01/2006 |
| 6951846 | Artemisinins with improved stability and bioavailability for therapeutic drug development and application A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic ... | 10/04/2005 |
| 6645966 | Treatment of malaria with farnesyl protein transferase inhibitors Disclosed is a method of treating Malaria comprising administering an effective amount of an FPT inhibitor to a patient in need of such treatment alone or in combination with an additional antimalarial agent and/or agent for reversing antimalarial resista... | 11/11/2003 |
| 6531487 | Indolo[2,1-b] quinazole-6, 12-dione antimalarial compounds and methods of treating malaria therewith Compounds, compositions and methods are provided for treating malaria parasites in vitro and in vivo by administering indolo[2,1-b]quinazoline-6,12-dione compounds of Formula I. ##STR1## wherein A, B, C, D, E, F, G and H are independently selected from ca... | 03/11/2003 |
| 6528519 | Use of tetrandrine and its derivatives to treat malaria The specification discloses the treatment of malaria through the use of tetrandrine and its derivatives.... | 03/04/2003 |
| 6428983 | Histone deacetylase as target for antiprotozoal agents Histone deacetylase inhibition provides a target for identifying potential antiprotozoal compounds. Histone deacetylase inhibitors are useful as therapeutic agents against protozoal infections.... | 08/06/2002 |
| 6362219 | Process for the preparation of a formulation of dihydroartemisinin for the control of wide spectrum of malaria The present invention relates to a synergistic formulation useful for the control of wide spectrum of malarial infections, which comprises a pharmaceutically effective amount of dihydroartemisinin and a vegetable oil.... | 03/26/2002 |
| 6306896 | Pharmaceutically active composition containing artemisinine and/or derivative of artemisinine The invention relates to a pharmaceutically active composition containing a substance which is active against malaria parasites and shows a high level of activity against multiresistant lines of Plasmodium falciparum. The inventive composition is characte... | 10/23/2001 |
| 6291488 | Preventing protozoal infections The invention relates to combinations of atovaquone and proguanil, their use in the treatment and prophylaxis of parasitic infections such as protozoal parasitic infections, e.g., malaria and toxoplasmosis, and infections caused by P. carinii and their us... | 09/18/2001 |
| 6284772 | Indolo[2,1-B] quinazole-6,12-dione antimalarial compounds and methods of treating malaria therewith Compounds, compositions and methods are provided for treating malaria parasites in vitro and in vivo by administering indolo[2,1-b]quinazoline-6,12-dione compounds of Formula I. ##STR1## wherein A, B, C, D, E, F, G and H are independently selected from ca... | 09/04/2001 |
| 6242428 | Nucleoside analogs and uses in treating Plasmodium falciparum infection The invention relates to novel nucleosides and nucleoside dimers containing an L-sugar in at least one of the nucleosides, and their pharmaceutical compositions.... | 06/05/2001 |
| 6214864 | Formulation of dihydroartemisinin for the control of wide spectrum of malaria The present invention relates to a synergistic formulation useful for the control of wide spectrum of malarial infections, which comprises a pharmaceutically effective amount of dihydroartemisinin and a vegetable oil.... | 04/10/2001 |
| 6214350 | Process for preparing an anti-viral medicinal product from plant extracts This invention relates to compositions derived from Chinese herbal medicines, medicinal plants and extracts thereof, and to their use for the treatment of animals infected with viruses, especially with hepatitis B virus (HBV), hepatitis C virus (HCV), and... | 04/10/2001 |
| 6194401 | Pharmaceutical compositions containing cyclosporine and a carrier comprising at least an ester of -glycerophosphoric acid A description is given of new pharmaceutical compositions containing cyclosporine, combined with a carrier comprising at least a derivative of -glycerophosphoric acid, such as -glycerophosphorylcholine, -glycerophosphorylserine, ... | 02/27/2001 |
| 6166046 | Combination of atovaquone with proguanil for the treatment of protozoal infections The invention relates to combinations of atovaquone and proguanil, their use in the treatment and prophylaxis of parasitic infections such as protozoal parasitic infections, e.g., malaria and toxoplasmosis, and infections caused by P. carinii and their us... | 12/26/2000 |
| 6114393 | Use of inhibitors of the sodium-hydrogen exchanger for the production of a pharmaceutical for the treatment of disorders which are caused by protozoa Inhibitors of the sodium-hydrogen exchanger are suitable on their own or in combination with other classes of active compound for the production of a medicament for the treament of diseases which are caused by protozoa; thus of diseases which are caused b... | 09/05/2000 |
| 6110697 | Histone deacetylase as target for antiprotozoal agents Histone deacetylase inhibition provides a target for identifying potential antiprotozoal compounds. Histone deacetylase inhibitors are useful as therapeutic agents against protozoal infections.... | 08/29/2000 |
| 6068987 | Histone deacetylase as target for antiprotozoal agents Histone deacetylase inhibition provides a target for identifying potential antiprotozoal compounds. Histone deacetylase inhibitors are useful as therapeutic agents against protozoal infections.... | 05/30/2000 |
| 6066623 | Polynucleotide vaccine protective against malaria, methods of protection and vector for delivering polynucleotide vaccines A first embodiment is a specific plasmid vector, pDIP/PyCSP.1, into which nucleotides encoding the targets of specific immune responses are inserted. These targets include, but are not limited to proteins and peptides. These plasmid constructs are incorpo... | 05/23/2000 |
| 6048867 | Biologically active rupununines A method of therapy wherein there is administered to a person in need of such therapy a pharmacologically effective amount of a rupununine having the formula: ##STR1##... | 04/11/2000 |
| 6043231 | Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines A method for treating mammals suffering from conditions associated with excess phospholipase A2 activity and/or production comprising administering to the mammal an effective amount of a non-antimicrobial tetracycline sufficient to inhibit exce... | 03/28/2000 |
| 5998476 | Synthetic polyunsaturated fatty acid analogues The invention provides polyunsaturated fatty acid compounds having antimalarial and/or neutrophil stimulatory activity, or anti-inflammatory activity. The polyunsaturated fatty acids contain a 16-26 carbon chain, 3-6 double bonds and are covalently couple... | 12/07/1999 |
| 5998449 | Combination of atovaquone with proguanil for the treatment of protozoal infections The invention relates to combinations of atovaquone and proguanil, their use in the treatment and propinylaxis of parasitic infections, such as protozoal parasitic infections, e.g. malaria and toxoplasmosis, and infections caused by P.carinii and their us... | 12/07/1999 |
| 5968987 | Halofantrine free base for the treatment of malaria and compositions The present invention relates to the use of halofantrine free base in the treatment of malarial infections. In particular, lipid-based formulations for oral and injectable use are disclosed.... | 10/19/1999 |
| 5955490 | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted... | 09/21/1999 |
| 5939402 | Nucleoside analogs and uses against parasitic infection The invention relates to novel nucleosides and nucleoside dimers containing an L-sugar in at least one of the nucleosides, and their pharmaceutical compositions.... | 08/17/1999 |
| 5928636 | Use of IL-12 and IFN for the treatment of infectious diseases The present invention provides a combination of IL-12 and IFN together with a pharmaceutically acceptable carrier useful for treatment and prophylaxis of infectious diseases, preferably chronic infectious diseases and more preferably viral infectio... | 07/27/1999 |
| 5902793 | Method for proliferating Vγ2Vδ2 T cells This invention is directed to a method for stimulating, the proliferation of Vγ2Vδ2 T cells comprising contacting Vγ2Vδ2 T cells with a Vγ2Vδ2 T cell proliferation stimulating amount of a compound selected from the group-consisting of a monoalkyl ph... | 05/11/1999 |
| 5885996 | Antiproliferative quinazolines Quinazoline compounds which demonstrate antiproliferative activity, such as antitumor activity, processes of preparing these compounds, pharmaceutical compositions containing these compounds, and the use of these compounds. These compounds inhibit the gro... | 03/23/1999 |
| 5883132 | 15-deoxyspergualin analogs, their use in therapeutics and their method of preparation The present invention relates to compounds selected from the group consisting of: (i) the compounds of the formula ##STR1## in which: R is a hydrogen atom, a group OH, a group OCH3 or a group CH2 OH, *C, in the case where R is n... | 03/16/1999 |
| 5874477 | Method of treatment for malaria utilizing serotonin receptor ligands The invention provides a method of preventing or treating malaria comprising administering a therapeutically effective amount of serotonin receptor ligand to reduce the pathological consequences of malaria infection in a patient, said serotonin receptor l... | 02/23/1999 |
| 5798106 | Protein This invention relates to a novel protein capable of inducing an immune response protective against human malarial infection caused by Plasmodium falciparum, and to the cloning and expression of a gene encoding the said protein. The invention further rela... | 08/25/1998 |
| 5753632 | Use of colloidal silica for the treatment of sickle-cell anaemia, malaria and exogenously induced leucopenias The use of colloidal silica for the treatment of sickle-cell anaemia, malaria and exogenously induced leucopenias leads to a significant improvement in the condition of the patients.... | 05/19/1998 |
| 5711966 | Method of treating malaria with desbutylhalofantrine This invention provides a method of treating patients suffering from malaria whilst avoiding cardioarrhythmias, the improvement thereof comprising the administration of desbutylhalofantrine in place of halofantrine. Dosage of 500 mg every six hours for th... | 01/27/1998 |
| 5683692 | Use of RIPonucleases for treating parasitic and viral diseases A method of treating viral and protozoal infections using RIPonucleases is provided.... | 11/04/1997 |
| 5677331 | Antimalarial compositions The invention relates to a synergistic antimalarial composition which comprises the antimalarial agent benflumetol and also an antimalarial agent from the artemisinine group such as artemether. The composition can be formulated into solid dosage forms suc... | 10/14/1997 |
| 5672624 | Endoperoxides useful as antiparasitic agents The present invention relates to novel biologically-active organic peroxides and to novel uses of both known and new organic peroxides. More specifically, this invention details organic endoperoxides having antiparasitic activity, methods for their prepar... | 09/30/1997 |