...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7419689 | Plant-based formulations for improving liver health The present invention is directed to plant based formulations for improving liver health by protecting the liver from alcohol and chemical insults and/or by inducing phase II enzymes. Formulations according to the present invention include wasabi root fiber powder, ... | 09/02/2008 |
| 7364758 | Pharmaceutical use of Graptopetalum and related plants The present invention relates to compositions comprising Graptopetalum and uses thereof Graptopetalum can protect animals from liver diseases and medical conditions, such as inflammation, steatosis, and fibrosis. In particular, Graptopetalum inh... | 04/29/2008 |
| 7335642 | Method for treating a viral infection related or a chemical toxin related hepatic injury with deltorphin D A method of modulating cytokine mediated hepatic injury by administering compound-D SEQ ID NO:1 to a mammal. A concentration of the compound in the range of about 0.5 mg/kg to about 20 mg/kg in a physiologically acceptable formulation blocks a cytokine cascade. A th... | 02/26/2008 |
| 7132450 | Hepatic disorder suppressant A hepatic disorder suppressant comprising extracts having hepatic disorder suppressing effect as effective ingredients, wherein the extracts is obtained by extracting an avocado plant and/or a processed product thereof with an organic solvent is disclosed. ... | 11/07/2006 |
| 7122541 | Methods of inhibiting metastases The invention relates to methods for preventing and treating disseminating cancers. Inhibition metastases of a primary tumor to a liver tissue is carried out by directly contacting a liver tissue with Taurolidine. ... | 10/17/2006 |
| 7101913 | Hepatic disorder suppressant A hepatic disorder suppressant comprising extracts having hepatic disorder suppressing effect as effective ingredients, wherein the extracts is obtained by extracting an avocado plant and/or a processed product thereof with an organic solvent is disclosed. ... | 09/05/2006 |
| 7081480 | Hepatic disorder suppressant A hepatic disorder suppressant comprising extracts having hepatic disorder suppressing effect as effective ingredients, wherein the extracts is obtained by extracting an avocado plant and/or a processed product thereof with an organic solvent is disclosed. ... | 07/25/2006 |
| 7078064 | Compositions and methods useful for treating and preventing chronic liver disease, chronic HCV infection and non-alcoholic steatohepatitis The invention relates generally to compositions comprising antioxidants useful for reducing oxidative stress and lipid peroxidation, and treating chronic liver disease, chronic hepatitis C virus infection and non-alcoholic steatohepatitis. In particular, the inventi... | 07/18/2006 |
| 7060262 | Stimulating neutrophil function to treat inflammatory bowel disease Immune stimulatory amounts of hematopoietic colony stimulating factors are administered to patients with inflammatory bowel disease. The factors include G-CSF and GM-CSF. These factors induce and maintain remission of the disease and its manifestations, whether with... | 06/13/2006 |
| 6995133 | Utilization of interferon alpha 5 in the treatment of viral hepatopathies The invention relates to the use of interferon alpha 5 in the treatment of viral hepatopathies. The invention describes the reduced synthesis of IFNα5 in the livers of patients with hepatitis C in comparison to healthy livers. The sub-type of IFN expressed in said ... | 02/07/2006 |
| 6989162 | Hepatoprotective agent of plant origin and a process thereof A process of isolation of pure Acteoside of high hepatoprotection from plant Colerbrookea oppositifolia, said process comprising steps of drying aerial parts of the plant, grounding the dried parts into powder, percolating the powder with water or ethanol for... | 01/24/2006 |
| 6942882 | Hepatic disorder suppressant A hepatic disorder suppressant comprising extracts having hepatic disorder suppressing effect as effective ingredients, wherein the extracts is obtained by extracting an avocado plant and/or a processed product thereof with an organic solvent is disclosed. ... | 09/13/2005 |
| 6875742 | Method for treating cytokine mediated hepatic injury A method of modulating cytokine mediated hepatic injury by administering compound-D SEQ ID NO:1 to a mammal. A concentration of the compound in the range of about 0.5 mg/kg to about 20 mg/kg in a physiologically acceptable formulation blocks a cytokine cascade. A th... | 04/05/2005 |
| 6863904 | Compositions and methods for prophylactic and therapeutic supplementation of nutrition in subjects The present invention relates to compositions without added iron and methods for prophylactic nutritional supplementation and therapeutic nutritional supplementation. Specifically, the method involves administering to an individual a composition comprising carotenoi... | 03/08/2005 |
| 6770635 | Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions Adverse inflammatory reactions can be treated by administrating to an organism a composition having diglucosylamine as the active ingredient. The preferred compound is di-Beta-D-glucopyranosylamine. A simple method for making diglucosylamine in high purity is obtain... | 08/03/2004 |
| 6753328 | Methods of inhibiting metastases The invention relates to methods for preventing and treating disseminating cancers. Inhibition metastases of a primary tumor to a liver tissue is carried out by directly contacting a liver tissue with Taurolidine. ... | 06/22/2004 |
| 6719969 | Treatment of liver disease and injury with CXC chemokines Disclosed is the surprising discovery that CXC chemokines function to induce rapid hepatocyte proliferation and liver regeneration after injury. The invention thus provides a range of compositions and methods for use in treating liver injury, including those suitabl... | 04/13/2004 |
| 6686332 | Method of treating depressed reticuloendothelial system function The present invention provides methods of treating adverse physiological effects associated with depressed reticuloendothelial system function comprising administering to a subject suffering from depressed reticuloendothelial system function an effective ... | 02/03/2004 |
| 6686375 | Composition useful as hepatoprotectants comprising extract of plant Cryptolepis buchanani and a method thereof The present invention relates to a composition useful for hepatoprotection, said composition comprising polar extract of plant Cryptolepis Buchanani and/or fractions of the said extract, and optionally pharmaceutically acceptable additives and a method of... | 02/03/2004 |
| 6685931 | Treatment of hepatitis C virus infections with interleukin-10 The hepatoprotective effect of IL-10 is described, in particular, the use of interleukin-10 in the treatment of liver damage (e.g. fibrosis or cirrhosis) in a difficult-to-treat patient afflicted with chronic hepatitis C virus infection who has failed to ... | 02/03/2004 |
| 6593364 | Triterpene derivatives and remedies for liver diseases A triterpene derivative useful for the treatment of hepatic disorders is disclosed. This compound comprises as an active ingredient a triterpene derivative represented by the following formula (I) or a salt thereof: ##STR1## wherein R1 represen... | 07/15/2003 |
| 6592910 | Methods of treating clinical diseases with isoflavones The present invention provides a method of treating or preventing certain medical conditions with isoflavones. More specifically, the invention provides a method of treating or preventing one or more of the following medical conditions: hepatic steatosis,... | 07/15/2003 |
| 6585974 | Preventives for hepatopathy An agent protective against drug-induced hepatopathy containing Lentinus edodes mycelium extract.... | 07/01/2003 |
| 6552070 | Health food useful for preventing liver and biliary dysfunctions containing an alkanoyl L-carnitine and Silybum marianum extract A health food/dietary supplement is disclosed, endowed with a protective action on liver function against exogenous and endogenous hepatoxic agents, the characterizing components of which are isovaleryl L-carnitine and/or propionyl L-carnitine and an extr... | 04/22/2003 |
| 6544954 | Stable galactose injection solutions The present invention provides stable galactose injection solutions, which contain 1 to 50% by weight of galactose, 0.01 to 1 M of a buffer solution, and 0.01 to 5% of an antioxidant. The preferred buffer solution is citrate buffer. The preferred anti-oxi... | 04/08/2003 |
| 6524610 | Nutritional composition made from conventional foods for mixing onsite in a blender and treating patients with hepatic disorders A nutritional composition made from conventional food mixed on-site in a blender and treating patients with hepatic disorders. The composition includes a vitamin A enriched conventional food, a vitamin D enriched conventional food, a vitamin E enriched co... | 02/25/2003 |
| 6514963 | Methods for the inhibition of egg production in trematodes The present invention comprises methods and compositions for use in inhibiting egg production by parasitic trematode worms comprising administering to an individual in need thereof an effective amount of an agent which transiently inhibits the influx of c... | 02/04/2003 |
| 6500418 | Stimulating neutrophil function to treat inflammatory bowel disease Immune stimulatory amounts of hematopoietic colony stimulating factors are administered to patients with inflammatory bowel disease. The factors include G-CSF and GM-CSF. These factors induce and maintain remission of the disease and its manifestations, w... | 12/31/2002 |
| 6495170 | Method of increasing the presence of glutathione in cells A method for increasing the presence of glutathione in cells including treating or preventing impaired liver function by administering a composition which includes a precursor of gluthathione, and enhancer of glutathione biosynthesis, and a third componen... | 12/17/2002 |
| 6468556 | Liver fat accumulation inhibitory composition, food additive for liver fat accumulation, inhibition, and method of inhibiting liver fat accumulation A method of inhibiting liver fat accumulation which comprises administering a conjugated linoleic acid homolog to a mammal or making the mammal ingest it; and a liver fat accumulation inhibitory composition characterized by containing an effective amount ... | 10/22/2002 |
| 6455078 | Medicinal herbal composition for treating liver diseases and HIV The present invention provides a herbal pharmaceutical composition for treating patients with liver diseases and/or HIV. The composition contains fifteen (15) ingredients, which are diffuse hedyotis, bistort rhizome, giant knotweed rhizome, Asiatic moonse... | 09/24/2002 |
| 6428821 | Oral micro-emulsion composition of silybin An oral micro-emulsion composition comprising a Carduus marianus extract, silybin or a silybin derivative; an organic solvent; a surfactant; and an oil provides a high in vivo bioavailability of silybin.... | 08/06/2002 |
| 6426329 | Immunosuppressant activity of insulin-like growth factor I (IGF-I) The invention provides a composition for improving an action of an immunosuppressant, comprising insulin-like growth factor I or its analog as an active ingredient.... | 07/30/2002 |
| 6426098 | Herbal compositions for hepatic disorders Compositions for treating hepatic disorders via oral or parenteral administration include Salvia miltiorrhiza and Polyporus umbellatus in proportions of about 1:1 to about 5:1, and may comprise from about 6% to about 30% of the total weight of the composi... | 07/30/2002 |
| 6416783 | Aspartic and malic acid inhibition of ss-glucuronidase Disclosed herein are infant dietary supplements containing L-aspartic and/or L-malic acid. The supplements are designed to inhibit ଲ-glucuronidase activity in breast feeding babies, and thereby suppress serum bilirubin levels and the incidence of ne... | 07/09/2002 |
| 6410009 | Pharmaceutical composition for treating hepatitis B virus (HBV) infection The invention provides a pharmaceutical composition for the treatment of hepatitis B virus (HBV) infection, comprising an amount of a soluble active agent which interacts with at least one of the binding sites between hIL6 and pS1 and between hIL6 and hep... | 06/25/2002 |
| 6380164 | Method for treating cytokine mediated hepatic injury A method of modulating cytokine mediated hepatic injury by administering deltorphins to a mammal. Deltorphin I SEQ ID NO:1, deltorphin II SEQ ID NO:2 or combinations of deltorphins I SEQ ID NO:1 and II SEQ ID NO:2 may be administered. A deltorphin concent... | 04/30/2002 |
| 6297229 | Use of ursodeoxycholic acid to treat nonalcoholic steatohepatitis A therapeutic method for the treatment of nonalcoholic steatohepatitis is provided, comprising administering to a patient in need of said treatment an effective amount of ursodeoxycholic acid or a pharmaceutically acceptable derivative thereof.... | 10/02/2001 |
| 6291521 | Anti-portal hypertensive agent The present invention provides an anti-portal hypertensive agent comprising a 15-keto-prostaglandin compound as an active ingredient.... | 09/18/2001 |
| 6274559 | Liver protection or treatment agents comprising asiatic acid derivatives as the active component Compositions and methods of treating or preventing hepatotoxicity utilizing asiatic acid derivatives of Formula 1 are disclosed. ##STR1##... | 08/14/2001 |