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Patent No. 5970981

Mouthguard made at least partially from an edible candy

A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.

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Class 514/889 - INTERFERON INDUCER


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter involving the inducement of the production
No. of patents: 113
Last issue date: 11/16/2010


1      
NumberTitleIssue Date
7834064Clinical method for the immunomodulatory and vaccine adjuvant use of poly-ICLC and other dsRNAs
An improved understanding and method for the clinical adjuvant and immunomodulatory use of dsRNAs and ply-ICLC in particular, alone or in conjunction with other drugs and various vaccines designed to prevent or treat various microbial, viral, neoplastic, autoimmune ...
11/16/2010
7229614Interferon gamma in the detection and treatment of angiomyolipomas
The present invention is directed to methods of treating or preventing angiomyolipomas by administering interferon gamma. It also encompasses methods for assessing the risk of a patient developing angiomyolipomas based upon interferon gamma expression. ...
06/12/2007
6656924Immunopotentiating compositions
The invention provides an immunopotentiating composition and to a composition accelerating the production of interferon-γ, both comprising lactosuclose as an active ingredient. In particular, the invention provides such compositions in the form of a food...
12/02/2003
6455060S(+) desmethylselegiline and its use to treat immune system dysfunction
The present invention provides novel compositions and methods for using the S(+) enantiomer of desmethylselegiline (N-methyl-N-(prop-2-ynyl)-2-aminophenylpropane), for the treatment of selegiline-responsive diseases and conditions. Diseases and conditions...
09/24/2002
6410034Dermal absorption-promoting agent
A dermal absorption-promoting agent comprising p-methane-3,8-diol and 1,3-butylene glycol as well as a topical formulation containing the same; and a dermal absorption-promoting agent further comprising 1,3-butylene glycol, as well as a topical formulatio...
06/25/2002
6365166Gel formulations for topical drug delivery
Pharmaceutical gel formulations for topical drug delivery include drug, colloidal silicon dioxide, triacetin and, preferably, propylene glycol. The gel formulations are well suited for topical delivery of the drug 4-amino-2-ethoxymethyl-଱,଱-di...
04/02/2002
6337325Combined preparation for the therapy of immune diseases
A combination preparation comprising a compound which has a phosphodiesterase-inhibiting action, and a compound which reduces the biologically effective intracellular Ca2+ content, is suitable for the treatment of immunological diseases....
01/08/2002
6221893Administration of histamine for therapeutic purposes
Methods for obtaining beneficial stable levels of circulating histamine are disclosed for use in methods for enhancing natural killer cell cytotoxicity. In such methods, a beneficial level of circulating histamine is attained and an agent whose ability to...
04/24/2001
6083534Pharmaceutical compositions for controlled release of soluble receptors
A controlled release pharmaceutical composition includes a biocompatible polymeric material, preferably polyethylene-vinyl acetate or poly(lactic-glucolic acid), having incorporated therein a soluble receptor capable of binding to its ligand and thus affe...
07/04/2000
6080782Cyclohexyl dihydrobenzofuranes
Compounds of formula I are selective cyclic nucleotide phosphodiesterase (PDE) inhibitors (namely of type IV). They and pharmaceutical compositions in which they are active ingredients are useful as bronchial therapeutics, for elimination of erectile dysf...
06/27/2000
6063373Enhanced activation of NK cells using an NK cell activator and a hydrogen peroxide scavenger or inhibitor
An improved method for the prevention of the inactivation of natural killer (NK) cells and the enhanced activation of NK cells in the presence of monocytes using a combination of a natural killer cell activator and a compound effective to inhibit the prod...
05/16/2000
6024983Composition for delivering bioactive agents for immune response and its preparation
A method, and compositions for use therein capable, of delivering a bioactive agent to an animal entailing the steps of encapsulating effective amounts of the agent in a biocompatible excipient to form microcapsules having a size less than approximately t...
02/15/2000
5990103Combination preparation for use in immunological diseases
A combination preparation comprising a compound which has a phosphodiesterase-inhibiting action, and a compound which reduces the biologically effective intracellular Ca2+ content, is suitable for the treatment of immunological diseases....
11/23/1999
5976569Diketopiperazine-based delivery systems
Compositions useful in the delivery of active agents are provided. These delivery compositions include (a) an active agent; and either (b)(1) a carrier of (i) at least one amino acid and (ii) at least one diketopiperazine or (b)(2) at least one mono-N-sub...
11/02/1999
5952313LPS antagonists and methods of making and using the same
Compositions for antagonizing gram negative bacterial endotoxic activity. Methods of antagonizing gram negative bacterial endotoxic activity. Methods of treating septic or toxic shock in a patient. Methods of treating or preventing a lipopolysaccharide me...
09/14/1999
5876703Flavanonol derivatives and hair-nourishing, hair-growing compositions containing the derivatives
The present invention relates to flavanonol derivatives represented by formula (1): ##STR1## (wherein R1 represents an alkyl group, and each of R2 and R3 represents a hydrogen atom, an alkyl group which may have a ...
03/02/1999
58639052',5'-phosphorothioate/phosphodiester oligoadenylates and anti-viral uses thereof
Optically active antiviral compounds having the formula ##STR1## wherein m is 0, 1, 2, or 3; n and q are selected from the group of 0 and 1, provided that n and q may not both be zero; and R, R1, and R2 are independently of each...
01/26/1999
5679644Methods of treating diseases using triterpenoid acid derivatives
Triterpenoid acid derivatives are described that exhibit dual pharmacophobic activities, specifically selectin ligand and leukotriene biosynthetic inhibitory activities, and that thus have significant applications for the treatment or prevention of certai...
10/21/1997
5624938Use of chloroquine to treat multiple sclerosis
This invention provides a pharmaceutical composition which comprises an amount of chloroquine effective to block MHC Class I recycling and an amount of a CD8+ T cell stimulatory agent effective to stimulate proliferation of CD8+ T cells to a concentration...
04/29/1997
5620703Stimulating hematopoietic activity with carboplatin or lobaplatin
A process for stimulating hematopoietic activity in animals which comprises administering to a patient in need therefor a therapeutically effective amount of an agent containing as its active ingredient a water-soluble or lipid-soluble transition metal co...
04/15/1997
55568402',5'-phosphorothioate oligoadenylates as anitiviral agents
Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internecleotide phosphorothioate linkages is of the Sp configuration possess in...
09/17/1996
5550111Dual action 2',5'-oligoadenylate antiviral derivatives and uses thereof
Viral infection is inhibited in mammals by administration of metabolically stable, non-toxic 2', 5'-oligoadenylate (2-5A) derivatives that have a dual therapeutic effect. The compounds activate the intracellular latent 2-5A dependent endoribonuclease RNas...
08/27/1996
5514661Immunological activity of rhamnolipids
Methods for treating various autoimmune diseases and for providing immunorestoration, by administering, to a subject in need thereof, an effective amount of a composition having, as active ingredient, one or more rhamnolipids of formula (I) ##STR1## ...
05/07/1996
5512290Compositions containing 2-acetyl-1-pyrroline
A powder-form composition of 2-acetyl-1-pyrroline incorporated with a support of maltodextrin and/or cyclodextrin. The composition is prepared by hydrolyzing a 2-(1-alkoxyethenyl)-1-pyrroline with an acid to obtain a reaction medium, adding an equimolar a...
04/30/1996
5496810Pyrimidine deoxyribonucleoside potentiation of combination therapy based on 5-fluorouracil and interferon
The applicants have discovered a method of treating malignancies which comprises administering effective amounts of 5-fluorouracil, interferon-଱ and a compound formula (I): ##STR1## wherein R is selected is selected from the group consisting of...
03/05/1996
5466675Immunological activity of rhamnolipids
Methods for treating various autoimmune diseases and for providing immunorestoration, by administering, to a subject in need thereof, an effective amount of a composition having, as active ingredient, one or more rhamnolipids of formula (I) ##STR1## ...
11/14/1995
5409905Cure for commond cold
Present invention is a non-toxic, flavor stable, pleasant tasting composition releasing Zn2+ from compositions containing a highly ionizable zinc compound other than zinc gluconate that reduces the duration of common colds in humans. The compos...
04/25/1995
5348739Combined anti-tumor therapy with interleukin-2 and histamine, analogs thereof or H2 -receptor agonists
A method of inhibiting the development of malignant tumors and the formation of metastases of malignant tumor cells in a subject carrying the comprises administering to the subject IL-2 and an agent selected from the group consisting of histamine, a hista...
09/20/1994
5288704Synergistic composition comprising a fibroblast growth factor and a sulfated polysaccharide, for use as antiviral agent
A pharmaceutcial composition is provided for use in the prevention or treatment of viral infections caused by enveloped viruses. The composition comprises a fibroblast growth factor, a sulfated polysaccharide with antiviral activity, and one or more pharm...
02/22/1994
5209920Evaluative means for detecting inflammatory reactivity
Inbred Lewis (LEW/N) female rats develop an arthritis in response to Group A streptococcal cell wall peptidoglycanpolysaccharide (SCW) which mimics human rheumatoid arthritis. Histocompatible Fischer (F344/N) rats, on the other hand, do not develop arthri...
05/11/1993
5157024Method of enhancing the activity of phagocytes including macrophages, modulating the cellular or humoral immune response, and reducing the adverse effects of stress in warm blooded animals
In one variant, the invention provides a method of enhancing the activity of phagocytes including macrophages, and in a further variant, a method of modulating the cellular or humoral immune response to warm blooded animals. The invention also provides a ...
10/20/1992
5124145Method for the prevention and treatment of bovine mastitis
A method for treating or preventing mastitis in cows is disclosed. The method contemplates the intramammary injection of bovine interferon-gamma. Interferon-gamma can be administered prior to infection to effectively suppress the rate, severity, and durat...
06/23/1992
5104650Uses of recombinant colony stimulating factor-1
A colony stimulating factor, CSF-1, is a lymphokine useful in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the muri...
04/14/1992
5093116Method of treating viral infection utilizing inteferon ଱ and pipyridamole
A method of enhancing the antiviral activity of IFN-଱ and especially human IFN-଱ is disclosed which comprises administration of Dipyridamole or a pharmaceutically acceptable salt thereof to a subject receiving IFN-଱. Also disclosed are p...
03/03/1992
5071872Method for improving interleukin-2 activity using aci-reductone compounds
A method for improving interleukin-2 induced lymphocyte killing of cancer cells comprises administering to a patient having cancer an effective amount of at least one aci-reductone compound containing a --C(OH).dbd.C(OH)--C.dbd.O redox functionality or a ...
12/10/1991
5063209Modulation of aids virus-related events by double-stranded RNAs
The use of mismatched dsRNA, e.g., AMPLIGEN.RTM. for the manufacture of compositions for use in the selective activation of a latent natural defense system within human cells, both cells already infected with AIDS virus as well as cells at risk to infecti...
11/05/1991
5017587Treatment of plantar warts using cycloheximide
The invention consists in healing of plantar warts with cycloheximide. Cycloheximide is used in various topical forms and methods of application to treat plantar warts. The concentrations employed ranges from 0.01% to 5.0% and the duration of treatment fr...
05/21/1991
500111916-substituted androstanes and 16-substituted androstenes
Compounds of the formula: ##STR1## are useful as anti-cancer, anti-obesity, anti-diabetic, anti-coronary agents, anti-aging agents, anti-hypolipidemic agents and anti-autoimmune agents....
03/19/1991
4937327Derivative of D.25, process for its preparation, its use as an immunostimulant, and pharmaceutical compositions containing the derivative
The present invention relates to a polysaccharide derivative, which is a derivative of D.25 in which the galactofuranose (Galf) residues of the linear polysaccharide chain have been converted at least partly to arabinose. It also relates to the...
06/26/1990
4933440Immunomodulators obtained semisynthetically from a bacterial polysaccharide isolated from a non-encapsulated mutant strain of Klebsiella pneumoniae
The invention relates to a polysaccharide derivative which is an amide, an ester, an ether, a salt or a quaternary ammonium derivative of D.25 with an amine, an acid or an alcohol....
06/12/1990
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