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| Number | Title | Issue Date |
| 6770741 | Brandykinin antagonist peptides The substitution of the L-Pro at the 7-position of the peptide hormone bradykinin or other substituted analogs of bradykinin with a D-configuration hydroxyproline ether or thioether converts bradykinin agonists into bradykinin antagonists. The invention further incl... | 08/03/2004 |
| 6387391 | Bioresorbable polymeric clayey and sticky substance This invention provides a claycy and sticky substance as a new biomaterial that cannot be found in the current medical field, which is bioresorbable, shows tackiness, plasticity and shape holding ability at a temperature of approximately from 30 to 40° C... | 05/14/2002 |
| 6288036 | Bradykinin type peptides The substitution of the L-Pro at the 7-position with D-Phe or D-Tic and substitution of the L-Phe at the 8-position with hydroxyproline ethers and thioethers of the peptide hormone bradykinin and other additional substituted analogs of bradykinin converts... | 09/11/2001 |
| 6218364 | Fluorinated neurokinin A antagonists Peptide derivatives which are antagonists of neurokinin A. The derivatives have a modified peptide bond having a reduced amide and a fluorinated alkyl attached to the nitrogen atom of the modified peptide bond. For example, Asp-Ser-Phe-Val-Gly-Leu.PSI.[CH... | 04/17/2001 |
| 6159985 | Imidazo-isoquinoline compounds, their compositions and uses The subject invention involves compounds having the structure: wherein the C --Nଲ and C5 -C6 bonds are independently single or double bonds, R1 is selected from alkyl, aryl, and heterocycle; R2-R13... | 12/12/2000 |
| 6083534 | Pharmaceutical compositions for controlled release of soluble receptors A controlled release pharmaceutical composition includes a biocompatible polymeric material, preferably polyethylene-vinyl acetate or poly(lactic-glucolic acid), having incorporated therein a soluble receptor capable of binding to its ligand and thus affe... | 07/04/2000 |
| 5792466 | Mimetic insect kinin analogs for insect control Novel pseudopeptide analogs of the insect kinin neuropeptide family which possess biological activity mimicking that of the naturally occurring neuropeptides are disclosed. By substituting a sterically hindered amino acid which is compatible with a turn c... | 08/11/1998 |
| 5648333 | Peptides having bradykinin antagonist action Peptides of the formula I A-B-C-E-F-K-P-G-M-F'-I (I), wherein the terms A, B, C, E, F, K, P, G, M, F', and I are defined in the specification, have bradykinin antagonist action. Their therapeutic utility includes all patholo... | 07/15/1997 |
| 5385889 | Bradykinin antagonist peptides The substitution of the L-Pro at the 7-position of the peptide hormone bradykinin or other substituted analogs of bradykinin with a D-configuration hydroxyproline ether or thioether converts bradykinin agonists into bradykinin antagonists. The invention f... | 01/31/1995 |
| 5162497 | Bradykinin analogs with non-peptide bond A bradykinin analog which contains nine or ten amino acid residues and at least one [CH2 NH] pseudopeptide bond, the analog being useful as an antagonist or agonist of the naturally occuring bradykinin.... | 11/10/1992 |
| 4923963 | Bradykinin antagonist peptides The substitution of the L-Pro at the 7-position of the peptide hormone bradykinin or other substituted analogs of bradykinin with an aliphatic, cyclic or aromatic amino acid of the D-configuration converts bradykinin agonists into a bradykinin antagonist.... | 05/08/1990 |
| 4152425 | Glucose containing infusion solution There is disclosed an infusion solution which is particularly useful for intravenous feeding. This solution comprises from about 100 to about 600 grams of glucose per liter of solution and from about 10 to about 3,000 μ grams of at least one kinin per li... | 05/01/1979 |
| 4146613 | Oral anti-diabetic drug composition There is provided an anti-diabetic drug to be taken orally. This drug comprises a sulfonyl urea and a kinin in retarded form. The kinin may be a Brady kinin or kallidin and is used in retarded form in an amount of from about 10μ grams to about 20 millig... | 03/27/1979 |
