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| Number | Title | Issue Date |
| 8093228 | Bisphosphonate formulation A bisphosphonate is formulated with an agent to reduce surface tension and/or reduce foaming in the stomach, leading to reduced reflux and oesophageal irritation in use and increased patient compliance. ... | 01/10/2012 |
| 7915237 | Production of pure stereoisomers of tricyclo[5.2.1.0]-dec-9-yl-xanthogenate and medicaments therefrom The invention relates to pharmaceutical formulations containing exo/exo-tricyclo[5.2.1.02.6]-dec-9-yl-xanthogenate, drugs containing exo/exo-tricyclo[5.2.1.02.6]-dec-9-yl-xanthogenate as active ingredient for the treatment of genital herpes, la... | 03/29/2011 |
| 7842679 | Phospholipid derivatives of DHA and methods for treating respiratory failure using the same Taught are pharmaceutical compositions comprising at least one phospholipid having at least one docosahexaenoyl (DHA) residue, such as a lecithin-DHA-type phospholipid, and methods for treating or preventing respiratory failure of a patient comprising administering ... | 11/30/2010 |
| 7838511 | Compositions and methods for treating, preventing and/or ameliorating cancers, the onset of cancers or the symptoms of cancers Compositions and methods are disclosed for treating, preventing and/or ameliorating the symptoms of cancers such as breast cancer, colon cancer, ovarian cancer, lung cancer, leukemia, skin cancer, prostate cancer, throat cancer, esophageal cancer etc., where the com... | 11/23/2010 |
| 7790702 | Lipid metabolism improving agent The present invention relates to a protein/phospholipid or protein hydrolyzate/phospholipid complex containing 10 wt % or more of bound phospholipid, a lipid metabolism improving agent comprising the complex, and a functional food comprising the complex. The ... | 09/07/2010 |
| 7767658 | Vaccine composition The present invention relates to a pharmaceutical composition comprising at least one vaccine antigen, which also comprises at least one phosphoric ester derivative of phosphatidylcholine having the structure: in which: | 08/03/2010 |
| 7759325 | Use of lecithin as a medication for the treatment of psoriasis Methods and compositions for the prevention and treatment of recent and old dermatitis, especially psoriasis, using lecithin or a lecithin-rich extract. According to one embodiment, phospholipids constituting the lecithin are esterified by Omega 3-type polyunsaturat... | 07/20/2010 |
| 7683044 | Sphingomyelin therapy of autoimmune disease Autoimmune disease therapy in a patient treated with apoptosis-inducing agents is enhanced by co-administration of sphingomyelin. The combination most likely enhances an autoimmune disease cell's ability to undergo ceramide-induced apoptosis by increasing the levels... | 03/23/2010 |
| 7674782 | Phosphorylcholine group-containing compound and method for producing same The present invention is a phosphorylcholine-containing chemical compound represented by the following formula (1) or (2). (CH3)3N+CH2CH2PO4−CH2COOH (1) | 03/09/2010 |
| 7473684 | Bisphosphonate formulation A bisphosphonate for treatment of osteoporosis is formulated with an amount of an antifoaming agent effective for reducing foaming in the stomach, leading to reduced reflux and oesophageal irritation in use and increased patient compliance. ... | 01/06/2009 |
| 7465717 | Process for releasing and extracting phosphatides from a phosphatide-containing matrix A process for releasing and extracting phosphatides from a phosphatide-containing matrix. The process includes (i) contacting the phosphatide-containing matrix with a solvent and a metal salt to release phosphatides from the matrix and form a phosphatide enriched so... | 12/16/2008 |
| 7354906 | Composition of anti-HIV drugs and anti-cortisol compounds and method for decreasing the side effects of anti-HIV drugs in a human The present invention is based, in part, upon the discovery that the use of an anti-HIV drug in combination with at least one cortisol blocker such as procaine, reduces the side effects associated with anti-HIV drugs. The invention also relates to a method of treati... | 04/08/2008 |
| 7354912 | Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced GI toxicity Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate and zwitterionic phospholipid. ... | 04/08/2008 |
| 7351428 | Phosphatidyl oligoglycerols In order to form liposomes with a longer half-life in blood, use is made of defined formula (A) ... | 04/01/2008 |
| 7344720 | Vaccine composition The present invention relates to a pharmaceutical composition comprising at least one vaccine antigen, which also comprises at least one phosphoric ester derivative of phosphatidylcholine having the structure: in which: | 03/18/2008 |
| 7338961 | Sphingosine kinase inhibitors The invention relates to substituted adamantane compounds, pharmaceutical compositions thereof, processes for their preparation, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angioge... | 03/04/2008 |
| 7318940 | Method for isolation of silymarin from seeds This invention relates to a method for the isolation of silymarin from silybum marianum seeds without precooling wherein the ground seeds are defatted using a hydrocarbon solvent, followed by extraction with a nontoxic medium polarity solvent, purification of... | 01/15/2008 |
| 7309692 | Inhibition of chronic myelogenous leukemic cell growth by liposomal-antisense oligodeoxy-nucleotides targeting to GRB2 or CRK1 The present invention provides novel compositions and methods for use in the treatment of cancer, specifically, in the treatment of chronic myelogenous leukemia (CML). The compositions contain antisense oligonucleotides that hybridize to Grb2 and Crk1 nucleic acids,... | 12/18/2007 |
| 7294621 | Lipid analogs for combating tumors The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294619 | Lipid analogs for inhibiting the activity of hepatitis B antigen The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294620 | Lipid analogs for inhibiting HIV-1 activity The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7288534 | Sphingomyelin enhancement of tumor therapy Cytotoxic tumor therapy in a patient is enhanced by co-administration of sphingomyelin. The invention most likely enhances a tumor cell's ability to undergo ceramide-induced apoptosis by increasing the levels of sphingomyelin in all cellular compartments, thereby pr... | 10/30/2007 |
| 7285288 | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides The present invention provides novel compositions and methods for use in the treatment of Bcl-2-associated diseases like cancer, specifically, in the treatment of follicular lymphoma (FL). The compositions contain antisense oligonucleotides that hybridize to Bcl-2 n... | 10/23/2007 |
| 7273604 | Anti-asthmatic combinations comprising surface active phospholipids Disclosed is a combination product for use in treating asthma and other respiratory conditions comprising a medicament comprising a surface active phospholipid composition in the form of a fine powder and an antiasthma drug. The product is arranged to be administere... | 09/25/2007 |
| 7265155 | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound Preparations and extracts of valerian, as well as isovaleramide, isovaleric acid, and certain structurally related compounds, exhibit clinically significant pharmacological properties that implicate a treatment for a variety of pathological conditions, including spa... | 09/04/2007 |
| 7262180 | Compositions and methods for the treatment of inflammatory conditions of mucosae, skin and the eye The present invention relates to compositions comprising telmesteine, glycyrrhetinic acid, and a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but not limited to, atopic dermatit... | 08/28/2007 |
| 7261903 | Lipid emulsions in the treatment of systemic poisoning Lipid emulsion compositions and methods of using such composition via intravenous infusion to reduce the bioavailability and toxicity of poisonous agents in the bloodstream. ... | 08/28/2007 |
| 7255869 | Anhydrous cosmetic compositions containing polyols Disclosed is anhydrous cosmetic compositions comprising: (a) a hydrophobic polyol; and (b) a hydrophilic polyol; which can provide improved conditioning benefits such as moisturizing benefit, and also can... | 08/14/2007 |
| 7244703 | Pharmaceutical compositions and methods for peptide treatment Compositions and methods for treating a patient with a pharmaceutically active peptide that combines a pharmaceutically active peptide, a permeation enhancer, and a carrier, are disclosed. ... | 07/17/2007 |
| 7241456 | Formulations for topical delivery of bioactive substances and methods for their use The invention relates to topical delivery of bioactive agents. More particularly, the invention relates to anhydrous formulations for percutaneous absorption. The invention provides formulations that allow efficient topical delivery of high concentrations of bioacti... | 07/10/2007 |
| 7235583 | Fatty acid-anticancer conjugates and uses thereof The invention provides conjugates of fatty acids and anticancer agents useful in treating cancer, and compositions and formulations thereof. Methods for using the conjugates also are provided. ... | 06/26/2007 |
| 7232514 | Method and composition for polishing a substrate Polishing compositions and methods for removing conductive materials from a substrate surface are provided. In one aspect, a composition includes an acid based electrolyte system, one or more chelating agents, one or more corrosion inhibitors, one or more inorganic ... | 06/19/2007 |
| 7220853 | Inhibition of chronic myelogenous leukemic cell growth by liposomal-antisense oligodeoxy-nucleotides targeting to Grb2 or Crk1 The present invention provides novel compositions and methods for use in the treatment of cancer, specifically, in the treatment of chronic myelogenous leukemia (CML). The compositions contain antisense oligonucleotides that hybridize to Grb2 and Crkl nucleic acids,... | 05/22/2007 |
| 7202276 | Use of 13-HODE as a regulator of vascular biocompatibility and an inhibitor of cell hyperplasia This invention relates to the regulation of vascular endothelium biocompatibility and to the inhibition of vessel wall cell and other types of cell hyperplasia following vessel wall dysfunction and/or injury. More particularly, the invention relates to the dietetic ... | 04/10/2007 |
| 7199102 | Orally administered peptides synergize statin activity This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis. The peptides typically range in length up to about 30 amino acids, comprise at least one class A amphipathic helix, and protect a phospholipid against oxidation by an oxi... | 04/03/2007 |
| 7199112 | Use of phospholipid arachidonic acids for increasing muscle mass in humans This invention discloses a method of increasing muscle mass comprising administering phospholipid arachidonic acid to a human in need thereof. ... | 04/03/2007 |
| 7166578 | Orally administered peptides synergize statin activity This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis. The peptides are highly stable and readily administered via an oral route. In addition, the peptides inhibit osteoporosis. When administered with a statin, the peptides e... | 01/23/2007 |
| 7160432 | Method and composition for polishing a substrate Polishing compositions and methods for removing conductive materials from a substrate surface are provided. In one aspect, a method is provided for processing a substrate to remove conductive material disposed over narrow feature definitions formed in a substrate at... | 01/09/2007 |
| 7148197 | Orally administered small peptides synergize statin activity This invention provides novel peptides for the treatment of atherosclerosis. In certain embodiments the peptide is X1-X2-X3-X4 where X1 and X4 are independently selected from the group consisting of a... | 12/12/2006 |
| 7144862 | Orally administered peptides to ameliorate atherosclerosis This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis. In certain embodiments, the peptide comprises an amino acid sequence that ranges in length from about 10 up to about 30 amino acids, that comprises at least one class A a... | 12/05/2006 |
