...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 7700660 | Method of treating chronic ulcers The invention provides a method of treating a chronic ulcer, such as a diabetic ulcer, comprising administering a therapeutic amount of a hydrogel matrix to the ulcer, the matrix composition comprising gelatin and a long chain carbohydrate. The matrix may further in... | 04/20/2010 |
| 7309502 | Pharmaceutical compositions for treating and saving and the method for the preparation thereof The present invention relates to a pharmaceutical composition and the method for the preparation thereof. The composition comprises 1.5˜6.9% (w/v) of one or more substances selected from sodium chloride, sodium bicarbonate, potassium chloride, magnesium sulfate, ca... | 12/18/2007 |
| 7118761 | Method for producing a silver-containing wound care device Wound care devices having a topically applied silver-based antimicrobial finish are provided. The finish comprises at least one silver ion-containing compound and at least one binder compound. The finish may be applied to a target substrate, such as a fiber, fabric,... | 10/10/2006 |
| 7063837 | Syrup composition containing phage associated lytic enzymes The present invention discloses a method and composition for the treatment of bacterial infections by the parenteral introduction of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for that bacteria and an appropriate carrier ... | 06/20/2006 |
| 6995164 | Methods of treating tumors The invention provides a method of inhibiting tumor growth in a mammal, by administering to the mammal composition containing taurolidine, taurultam, or a biologically active derivative thereof. The composition is administered to directly contact a tumor cell at a d... | 02/07/2006 |
| 6974594 | Method of preparing biological materials and preparations produced using same Methods for preparing products containing moisture-sensitive materials, including biological materials such as proteins, peptides or live cells, comprising at least the steps: (i) providing a coating liquid comprising at least one active, a sugar polymer and a water... | 12/13/2005 |
| 6964959 | Use of a methylol-containing compound to treat tumors The invention provides a method of inhibiting tumor growth in a mammal, by administering to the mammal composition containing methylol-containing compound. The composition is administered to directly contact a tumor cell at a dose sufficient to induce cell death by ... | 11/15/2005 |
| 6914051 | Penetrating antibiotic gel for soft tissue diseases A penetrating antibiotic gel for treating pain, inflammation and other pathological conditions affecting musculoskeletal tissues and other soft tissues of the body. The composition includes an antibiotic compound and a mobilizing agent in an amount sufficient to ena... | 07/05/2005 |
| 6878389 | Azide method and composition for controlling deleterious organisms Disclosed is both a method and composition for controlling deleterious organisms, such as insects, nematodes and weeds by applying a compound comprised of a liquid medium comprising an azide and an azide stabilizer. The azide can be selected from the group consistin... | 04/12/2005 |
| 6855334 | Controlled delivery of active agents Controlled release of active agents from sustained release push delivery devices having high drug loading are described wherein residual drug content in the device is minimized by the utilization of a flow-promoting layer between a semi-permeable wall and drug layer... | 02/15/2005 |
| 6797260 | Bleeding control and healing aid compositions and methods of use A composition is disclosed which has been shown to stop or control bleeding and seal open small blood vessels while accelerating the healing process of abraded oral “gum” and other “skin” (epithelial) tissues. The composition is preferably in the form of a p... | 09/28/2004 |
| 6790453 | Encapsulation compositions and process for preparing the same Encapsulation compositions in which an encapsulate (A) is encapsulated in a matrix (B) may be prepared by: (i) mixing matrix (B) with a liquid plasticizer and encapsulate (A) in an extruder, to obtain a melted mixture of encapsulate (A) and matrix (B); and | 09/14/2004 |
| 6703011 | Application of film forming technology to fragrance control release systems; and resultant fragrance control release systems Described is a fragrance control release system which is an emulsifier-free, single phase, nonporous, continuous, permeable polymeric film having a substantially uniform thickness of from about 1 up to about 150 microns, having entrapped and dissolved the... | 03/09/2004 |
| 6667059 | Odor-masking coating for a pharmaceutical preparation A coating for masking or reducing the detectable presence of certain characteristic odor or odors, taste or tastes of pharmaceutical preparations, particularly Valerian extracts, is described. The coating comprises from one to three coating compartments, ... | 12/23/2003 |
| 6652840 | Bleeding control and healing aid compositions and methods of use A composition is disclosed which has been shown to stop or control bleeding and seal open small blood vessels while accelerating the healing process of abraded oral "gum" and other "skin" (epithelial) tissues. The composition is preferably in the form of ... | 11/25/2003 |
| 6627224 | Low dose entecavir formulation and use Compositions containing a low dose of entecavir are administered on a daily basis to treat hepatitis B virus infection and/or co-infections. Formulations for the oral administration of a low dose of entecavir are provided. Other pharmaceutically active su... | 09/30/2003 |
| 6620432 | Phenytoin sodium pharmaceutical compositions A pharmaceutical composition is provided containing an admixture of phenytoin sodium and an erodible matrix which extends the release of the phenytoin sodium over about a two hour period. The erodible matrix comprises binder(s) and diluent(s) which contro... | 09/16/2003 |
| 6569454 | Simple tablet compression using gelatin The present invention comprises a method of tablet preparation. The invention provides a simple and cost effective method to compress good tablets.... | 05/27/2003 |
| 6491946 | Pharmaceutical levothyroxine preparation The invention relates to a pharmaceutical preparation comprising levothyroxine sodium, potassium iodide, microcrystalline cellulose and binding agent, which is free of antioxidants or further auxiliaries, and processes for its production.... | 12/10/2002 |
| 6485746 | Controlled-release sedative-hypnotic compositions and methods related thereto Controlled-release formulations providing a "pulsed" plasma profile of a sedative-hypnotic compound having a particularly short half-life are provided. The formulation contains a sedative-hypnotic compound or precursor thereof that is metabolized to gener... | 11/26/2002 |
| 6468959 | Peroral dosage form for peptide containing medicaments, in particular insulin There is provided a plural dosage form for peptide pharmaceuticals comprising a matrix of gelatin or gelatin derivative having distributed therein the peptide pharmaceutical in particular insulin, as well as, pharmaceutically conventional carriers and add... | 10/22/2002 |
| 6465010 | Means for creating a mass having structural integrity The present invention relates to a means for creating a mass having structural integrity, including a rapidly disintegratable tablet for administration with or without the use of water. The present invention has a wide variety of different uses and applic... | 10/15/2002 |
| 6419956 | Odor-masking coating for a pharmaceutical preparation A coating for masking or reducing the detectable presence of certain characteristic odor or odors, taste or tastes of pharmaceutical preparations, particularly Valerian extracts, is described. The coating comprises from one to three coating compartments, ... | 07/16/2002 |
| 6413541 | Disintegrating tablet in oral cavity and production thereof Method for producing intrabuccally disintegrating tablets, which comprises the following Steps (a), (b) and (c), wherein a medicament is mixed before granulation or tabletting: (a) a step of dissolving at least one saccharide having a high solubility in w... | 07/02/2002 |
| 6413713 | Method for preserving blood platelets A method for preserving blood platelets is described. The method uses 1%-3% gelatin in the platelet preservation medium, and storing the platelets in the preservation medium at temperatures below 0° C. and at least 70 atmospheres pressure for at least on... | 07/02/2002 |
| 6387391 | Bioresorbable polymeric clayey and sticky substance This invention provides a claycy and sticky substance as a new biomaterial that cannot be found in the current medical field, which is bioresorbable, shows tackiness, plasticity and shape holding ability at a temperature of approximately from 30 to 40° C... | 05/14/2002 |
| 6368626 | Controlled delivery of active agents Controlled release of active agents from sustained release push delivery devices having high drug loading are described wherein residual drug content in the device is minimized by the utilization of a flow-promoting layer between a semi-permeable wall and... | 04/09/2002 |
| 6352974 | Oral calcitonin pharmaceutical compositions and methods of making the same The present invention relates to novel compositions, in particular to compositions comprising calcitonin or a fragment or conjugate thereof and to methods for preparing such compositions. It also relates to oral formulations comprising the compositions an... | 03/05/2002 |
| 6350469 | Rapidly disintegrating methylcellulose tablets The present invention relates to a novel pharmaceutical composition and process for preparing swallowable methylcellulose tablets that disintegrate rapidly and meet USP standards in 0.1N hydrochloric acid as well as water.... | 02/26/2002 |
| 6346515 | Collegan-based matrix A collagen matrix comprises collagen fibrils which are cross-linked to one another by reducing sugar or a reducing sugar derivative. The collagen matrix may be formed into a membrane useful in guided tissue regeneration.... | 02/12/2002 |
| 6315994 | Medium and matrix for long-term proliferation of cells A cell culture medium and hydrogel matrix for long term storage and proliferation of cells is provided. The cell culture medium and hydrogel matrix include an effective amount of polar amino acids, the polar amino acids selected from the group consisting ... | 11/13/2001 |
| 6284270 | Means for creating a mass having structural integrity The present invention relates to a means for creating a mass having structural integrity, including a rapidly disintegratable tablet for administration with or without the use of water. The present invention has a wide variety of different uses and applic... | 09/04/2001 |
| 6277394 | Collagen-polymer matrices with differential biodegradability The current invention is a biomedical implant comprising a biomedical matrix material and a biodegradable porosifying agent. As the porosifying agent degrades in situ, an implant with an inter-connecting network is formed. The resultant mechanically stabl... | 08/21/2001 |
| 6274570 | Pesticidal compositions A liquid pesticidal composition, which is substantially free of water, comprising a hydrophobic pesticide or mixture of pesticides dissolved in an organic solvent and comprising as surfactants (a) a castor oil ethoxylate having 30-50 mol ethoxylate, (b) a... | 08/14/2001 |
| 6274168 | Phenytoin sodium pharmaceutical compositions A pharmaceutical composition is provided containing an admixture of phenytoin sodium and an erodible matrix which extends the release of the phenytoin sodium over about a two hour period. The erodible matrix comprises binder(s) and diluent(s) which contro... | 08/14/2001 |
| 6245350 | Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process A process for encapsulation of caplets in a capsule comprises the following steps: a. providing empty capsule parts; b. filling at least one of said capsule parts with one or more caplets; c. putting said capsule parts together; and d. treating the combin... | 06/12/2001 |
| 6231881 | Medium and matrix for long-term proliferation of cells A cell culture medium and hydrogel matrix for long term storage and proliferation of cells is provided. The cell culture medium and hydrogel matrix include an effective amount of polar amino acids, the polar amino acids selected from the group consisting ... | 05/15/2001 |
| 6224905 | Biconvex rapidly disintegrating dosage forms A method for preparing solid rapidly disintegrating dosage forms shaped as biconvex tablets having symmetrical top and bottom surfaces and dosage forms obtainable thereby.... | 05/01/2001 |
| 6221393 | Pharmaceutical compositions in the form of sustained-release tablets based on high molecular weight polysaccharide granules The present invention relates to a delayed-release pharmaceutical composition which is in the form of tablets prepared by direct tableting and consisting of at least one active principle and a matrix which gives the said composition its delayed-release ef... | 04/24/2001 |
| 6193986 | Oily composition with increased stability and process for producing the same An oily composition having excellent storability and forming no precipitate of an ingredient selected from the group of gelatin and gum arabic during the storage for a long period of time is provided. This composition is composed of a solid phase comprisi... | 02/27/2001 |