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| Number | Title | Issue Date |
| 8030361 | Cell culture carrier implantable in vivo A cell cultivation carrier implantable in vivo having independent pore with opening of 100 μm-1000 μm on the surface thereof produced by neutralization•gellation of collagen acidic solution, said collagen acidic solution is preliminary prepared by passing throug... | 10/04/2011 |
| 7501455 | Pharmaceutical compositions containing plasma protein The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to ... | 03/10/2009 |
| 7348319 | Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same The present invention relates to nitric oxide-releasing amidine diazeniundiolates, compositions comprising same, methods of using same, and a method for preparing same from imidate diazeniumdiolates and primary or secondary amines. ... | 03/25/2008 |
| 7307142 | Leptin antagonists The invention relates to synthetic leptin antagonists in which at least two amino acid residues of the sequence LDFI/S of the hydrophobic binding site at positions 39-42 of a leptin polypeptide sequence are substituted with different amino acid residue... | 12/11/2007 |
| 7303756 | Multiphase system The invention relates to a preparation comprising a carrier phase and at least one further phase which cannot be mixed with the carrier phase or only partially mixed therewith, wherein the change in ambient conditions alters the viscosity of the carrier phase. The i... | 12/04/2007 |
| RE39713 | Polymerizable biodegradable polymers including carbonate or dioxanone linkages Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and methods of preparation and use thereof are described. The macromers a... | 07/03/2007 |
| 7229642 | Amino acid modulated extended release dosage form Disclosed herein is a oral extended release dosage form comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an intragranular polymer in which the granule is dispersed within a hydrophilic extr... | 06/12/2007 |
| 7186443 | Systems and methods for dispensing an anti-traction, mobility denial material Systems and methods for dispensing an anti-traction, mobility denial material on a target surface. In various exemplary embodiments, a method of dispensing an anti-traction material on a target surface includes providing a polymer particle powder to a first section ... | 03/06/2007 |
| 7172755 | Methods for making functionalized polymers Polymers containing amino acid and/or polypeptide moieties in their backbones or pendant to their backbones are made by metathesis. A method of making an amino acid or polypeptide containing polymer includes the steps of: providing a amino acid, amino alcohol, or po... | 02/06/2007 |
| 7169770 | Method of enhancing reproductive performance in sows The present invention relates to supplementing the diets to sows during the periods of gestation, lactation, and breeding by feeding L-carnitine and chromium. The supplementation enhances pork productivity by increasing the number of pigs born alive in the subsequen... | 01/30/2007 |
| 7122553 | Liposomal formulation of irinotecan The present invention is for novel compositions and methods for treating cancer, particularly, for treating cancer in mammals and more particularly in humans. The therapeutic compositions of the present invention include liposome entrapped irinotecan in which the li... | 10/17/2006 |
| 7119124 | Pharmaceutical compositions containing plasma protein The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to ... | 10/10/2006 |
| 7115586 | Non-inclusion cyclodextrin complexes The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization of the active ingredient is enhanced by combining it with β-cyclode... | 10/03/2006 |
| 7109166 | Sustained release formulation of a peptide This invention is directed to a sustained release composition comprised of Compound (A) having the formula or a pharmaceutically acceptable salt thereof, and a copolymer comprised of poly-(I)-lactic-glycolic-tart... | 09/19/2006 |
| 7109255 | Bioresorbable hydrogel compositions for implantable prostheses Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable functional groups per polymer chain. Crosslinking of these polymers c... | 09/19/2006 |
| 7084132 | Artemisinins with improved stability and bioavailability for therapeutic drug development and application A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic ... | 08/01/2006 |
| 7078378 | Method of tissue repair II A substantially solid biomolecular solder for joining tissue comprising a partially denatured biomolecule. The solder can be formed into shapes to suit the needs of a user. The invention also relates to methods for joining tissue and methods for preparing the solder... | 07/18/2006 |
| 7070797 | Method of treating hematologic tumors and cancers Multiple myeloma and other hematologic tumors and/or malignancies can be treated by administration of a G1 and/or S phase drug, which is preferably β-lapachone, or a derivative or analog thereof, combined with a G2/M phase drug such as a taxane derivative, which is... | 07/04/2006 |
| 7045552 | Pharmaceutical composition for improved administration of HIV gp41-derived peptides, and its use in therapy Provided is a pharmaceutical composition comprising a solution comprised of synthetic peptide in a final concentration of not less than 70 mg/ml in admixture with a polyol; wherein the synthetic peptide is an HIV fusion inhibitor, and wherein the polyol is in a fina... | 05/16/2006 |
| 7022318 | Kit of parts for treating urinary incontinence in mammals Disclosed are methods for treating urinary incontinence in a mammal wherein a composition comprising a biocompatible polymer, a biocompatible solvent, and a contrast agent is delivered to the periurethral tissue of the mammal. ... | 04/04/2006 |
| 7018654 | Pharmaceutical composition containing an active agent in an amino acid copolymer structure A method of protecting a chemical compound from degradation comprising combining the chemical compound with an amino acid polymer. Disclosed are methods of combining chemical compounds with synthetic amino acid polymers for protection from degradation of the chemica... | 03/28/2006 |
| 7019192 | Composition for filling bone defects The invention is directed toward a formable bone composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing compound of demineralized lyophilized allograft bone particles. The particle size ran... | 03/28/2006 |
| 7001604 | Cosmetic composition A cosmetic composition, especially for use on aged and/or stressed skin is described, whereby apart from water at least one substance forming lamellar structures with water is present in the composition. The composition further contains ... | 02/21/2006 |
| 7001881 | Tribonectins The invention features a tribonectin and a method of tribosupplementation carried out by administering tribonectins directly to an injured or arthritic joint. ... | 02/21/2006 |
| 6994873 | Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration This invention refers to: multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional release granules, suitable for once-a-day adm... | 02/07/2006 |
| 6960562 | Tribonectin polypeptides and uses thereof The invention features a lubricating polyeptide and methods of lubricating joints or other tissues by administering the polypeptide systemically or directly to tissues. ... | 11/01/2005 |
| 6951846 | Artemisinins with improved stability and bioavailability for therapeutic drug development and application A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation shields the peroxide portion of the artemisinin backbone from hydrolytic ... | 10/04/2005 |
| 6949625 | Injectable implant of insoluble globin A preparation is provided which can be injected or implanted into the human or animal body, and which comprises, as main component, globin that is insoluble at physiological pH, biocompatible and sterile. ... | 09/27/2005 |
| 6946499 | Bioresorbable hydrogel compositions for implantable prostheses Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable functional groups per polymer chain. Crosslinking of these polymers c... | 09/20/2005 |
| 6946145 | Block copolymers based on poly(ortho esters) containing amine groups Block copolymers based on poly(ortho esters) containing amine groups. These block copolymers have both hydrophilic and hydrophobic blocks. They form micelles in aqueous solution, making them suitable for encapsulation or solubilization of hydrophobic or water-insolu... | 09/20/2005 |
| 6936275 | Amino acid modulated extended release dosage form Disclosed herein is a oral extended release dosage form comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an intragranular polymer in which the granule is dispersed within a hydrophilic extr... | 08/30/2005 |
| 6936280 | Method for preparing a composition by extraction of mother-of-pearl, composition obtained by said method and use thereof in cosmetics and dermatology A method for preparing a composition, comprising a) reducing mother-of-pearl into powder with grain size distribution ranging between about 1 and about 300 μm; b) placing the obtained powder in close contact with an extracting agent in the form of a hydroglycol sol... | 08/30/2005 |
| 6929955 | Interactive system for presenting and eliminating substances The present invention relates to an interactive system comprising at least one active surface of plastic from monomers containing at least one structural element derived from a carbon dioxide (A), and at least one substance associated to a linker with at least one s... | 08/16/2005 |
| 6911478 | Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitric oxide-releasing amidine- a... | 06/28/2005 |
| 6893664 | Particle delivery techniques A method is provided for in vivo or ex vivo delivery of a preparation of powdered nucleic acid molecules into vertebrate tissue for transformation of cells in the tissue using needleless injection techniques. The method can be used to deliver therapeutically relevan... | 05/17/2005 |
| 6878389 | Azide method and composition for controlling deleterious organisms Disclosed is both a method and composition for controlling deleterious organisms, such as insects, nematodes and weeds by applying a compound comprised of a liquid medium comprising an azide and an azide stabilizer. The azide can be selected from the group consistin... | 04/12/2005 |
| 6867181 | Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing polymer and a free amino group-containing drug which are ionically bonded to each other. ... | 03/15/2005 |
| 6855727 | Muscular fatigue-controlling composition and method for providing muscular fatigue-controlling effect An antifatigue composition for reducing muscular fatigue or the like during or after exercise, which includes an imidazole compound obtained from extracts of fishes, shelifishes, fowl, flesh or the like, as an active ingredient. The imidazole compound in the antifat... | 02/15/2005 |
| 6838431 | Nutritional intervention composition containing a source of proteinase inhibitor extending post meal satiety The invention relates to a nutritional intervention composition in powder form that is taken before a meal and that extends post meal satiety. The compositions of the invention are comprised of at least one protein, C12-18 fatty acids, preferably oleic ac... | 01/04/2005 |
| 6828334 | Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition The present invention relates to pharmaceutical compositions containing fenofibrate in the form of an inclusion complex with cyclodextrin, having high dissolution profile and in vivo enhanced bioavailability as compared with plain micronized fenofibrate compositions... | 12/07/2004 |
